Nitfuin 100mg Tablet Sr: Complete Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Blood in stool or vomit
- Severe abdominal pain
- Chest pain or difficulty breathing
- Severe headache with visual changes
- Sudden swelling of face, lips, or throat
- Yellowing of skin or eyes
- Decreased urine output
- Numbness or tingling in hands or feet
- Persistent cough or shortness of breath
- Unusual tiredness, easy bruising, or fever with sore throat
If experiencing severe symptoms, call emergency services immediately.
What is nitfuin 100mg tablet sr used for?
This medicine is a sustained-release tablet containing nitrofurantoin, an antibiotic used to treat and prevent uncomplicated urinary tract infections. It works by killing susceptible bacteria in the urine. Take it with food, swallow the tablet whole, and complete the full course prescribed by your clinician.
- Generic Name: Information coming soon
- Manufacturer: Multiple manufacturers
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 nitfuin 100mg tablet sr के बारे में (Hindi Summary)
उपयोग: यह दवा नाइट्रोफ्यूरेंटोइन का सस्टेन्ड-रिलीज़ टैबलेट है, जिसका उपयोग मूत्र मार्ग के संक्रमण (यूटीआई) के इलाज और रोकथाम के लिए किया जाता है। यह मूत्र मार्ग में बैक्टीरिया को मारकर काम करती है। यह दवा उन लोगों के लिए है जिन्हें बार-बार मूत्र मार्ग में संक्रमण होता है या जिन्हें तीव्र सिस्टाइटिस है। इसे भोजन के साथ लें और टैबलेट को पूरा निगलें, चबाएं या तोड़ें नहीं। डॉक्टर द्वारा बताई गई पूरी अवधि तक दवा लें, भले ही लक्षण जल्दी ठीक हो जाएं। गुर्दे की गंभीर बीमारी, गर्भावस्था के अंतिम चरण, एक महीने से छोटे शिशुओं और जी6पीडी की कमी वाले लोगों को यह दवा नहीं लेनी चाहिए।
साइड इफेक्ट्स: इस दवा से आमतौर पर मतली, सिरदर्द, पेट में गैस, ढीले दस्त और पेशाब का रंग भूरा या गहरा पीला हो सकता है। ये आमतौर पर हल्के होते हैं और अपने आप ठीक हो जाते हैं। कभी-कभी यह दवा फेफड़ों, नसों, लिवर या खून से जुड़ी गंभीर समस्याएं पैदा कर सकती है। अगर सांस लेने में तकलीफ, लगातार खांसी, हाथ-पैर में झुनझुनी, आंखों या त्वचा का पीलापन, असामान्य थकान या आसानी से चोट लगना महसूस हो, तो तुरंत डॉक्टर से मिलें। चेहरे, होंठ या गले में सूजन, गंभीर दाने या सांस लेने में कठिनाई हो तो तुरंत आपातकालीन चिकित्सा सहायता लें।
सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें और अपनी मर्जी से डोज न बदलें। सस्टेन्ड-रिलीज़ टैबलेट को एक गिलास पानी के साथ पूरा निगलें, इसे चबाएं, तोड़ें या कुचलें नहीं। इसे भोजन के साथ लें ताकि पेट की तकलीफ कम हो और दवा अच्छी तरह अवशोषित हो। दिन भर खूब पानी पिएं। मैग्नीशियम ट्राइसिलिकेट वाले एंटासिड को इस दवा से दो घंटे पहले या बाद में न लें। अगर आपको गुर्दे, लिवर, खून या नसों की बीमारी है, तो डॉक्टर को पहले बताएं। यह दवा किसी और के साथ साझा न करें।
💊 nitfuin 100mg tablet sr Uses & Benefits
[{"condition":"Acute uncomplicated urinary tract infection (cystitis)","description":"This medicine is used to treat first-time or occasional bladder infections caused by susceptible bacteria such as Escherichia coli, Enterococcus species, and Staphylococcus saprophyticus.","evidence":"Well-established"},{"condition":"Recurrent urinary tract infection prophylaxis","description":"This medicine is prescribed at a low dose for several weeks or months to prevent repeated urinary tract infections in people who experience frequent episodes.","evidence":"Well-established"},{"condition":"Urinary tract infection in pregnancy (selected cases)","description":"This medicine may be used in pregnancy for susceptible infections, but it is avoided near term and in women with glucose-6-phosphate dehydrogenase deficiency.","evidence":"Moderate"},{"condition":"Catheter-associated urinary tract infection prevention","description":"In selected patients, this medicine may be used to reduce the risk of urinary tract infections associated with long-term catheter use.","evidence":"Limited"}]
Off-label uses: [{"condition":"Prophylaxis before urological procedures","description":"Sometimes prescribed off-label to prevent infection before certain urinary tract procedures in patients with a history of recurrent infections.","evidence":"Limited"}]
Primary treatment for: Urinary tract infection
Also treats: Recurrent urinary tract infection, Catheter-associated urinary tract infection
📋 Drug Information
| Generic Name(s) | Information coming soon |
| Brand Name | nitfuin 100mg tablet sr |
| Manufacturer | Multiple manufacturers |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | UROLOGY |
| Action Class | Urinary Antiseptic-Nitrofurantoin |
| Route of Administration | Oral |
| Storage | Store this medicine at room temperature between 15°C and 30°C. Keep it in the original container, tightly closed, away from direct sunlight, heat, and moisture. Do not store it in the bathroom. |
| Shelf Life | The shelf life of this medicine is typically 24 to 36 months from the date of manufacture. Check the expiry date on the pack before use. Do not use this medicine after the expiry date. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine works by entering susceptible bacteria and being converted by bacterial enzymes into reactive intermediates that damage bacterial DNA, RNA, proteins, and cell wall components. This multi-target action disrupts bacterial metabolism and prevents the bacteria from growing and multiplying. Because this medicine acts at several sites, bacteria develop resistance to it very slowly, which is one reason it remains useful for urinary tract infections. The sustained-release formulation delivers the active ingredient gradually, maintaining effective antibacterial levels in the urine over a longer period.
Mechanism Steps
💡 How to Take nitfuin 100mg tablet sr
Strength: This medicine is available as a sustained-release tablet containing 100 mg of nitrofurantoin.
Dosage Information
| Adult Dosage | The usual adult dose of this medicine for treating acute uncomplicated urinary tract infection is 100 mg twice daily for 5 to 7 days, taken with food. For prevention of recurrent urinary tract infections, a lower dose such as 50 mg to 100 mg once daily at bedtime may be prescribed for several weeks or months. The exact dose and duration depend on the indication, the severity of infection, kidney function, and your clinician's judgment. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Do not adjust the dose on your own. |
| Pediatric Dosage | Pediatric dosing of this medicine is not established from available information for the sustained-release tablet form. Sustained-release tablets are generally not recommended for children. Consult a pediatrician for appropriate dosing and formulation. |
| Elderly Dosage | Older adults may need a lower dose of this medicine because kidney function often declines with age. Kidney function should be checked before and during treatment. Dose must be individualized by a qualified clinician based on kidney function and other health conditions. |
| Renal Impairment | This medicine should be avoided in people with significant kidney impairment because reduced excretion can lead to higher blood levels and increased risk of side effects, especially nerve damage. If used in mild kidney impairment, the dose may need to be reduced and kidney function monitored closely. Dose must be individualized by a qualified clinician based on kidney function. |
| Hepatic Impairment | This medicine is partly metabolized in the liver. In people with liver impairment, the dose may need to be adjusted and liver function monitored. Dose must be individualized by a qualified clinician based on liver function. |
| Maximum Daily Dose | The maximum recommended adult daily dose of this medicine for treating urinary tract infection is 200 mg per day in divided doses. For prevention, the maximum daily dose is usually 100 mg. Do not exceed the dose prescribed by your clinician. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of nitfuin 100mg tablet sr
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Magnesium trisilicate antacids | Major | |
| Fluoroquinolone antibiotics | Major | |
| Live typhoid vaccine | Major | |
| Warfarin | Moderate | |
| Sulfinpyrazone | Moderate | |
| Probenecid | Moderate | |
| Anticholinergic medicines | Minor | |
| Oral contraceptives | Minor |
🚨 Major Interactions
- Magnesium trisilicate antacids
- Fluoroquinolone antibiotics (for example, ciprofloxacin)
- Live typhoid vaccine
⚡ Moderate Interactions
- Warfarin
- Sulfinpyrazone
- Probenecid
🍷 Alcohol Interaction
Alcohol may worsen stomach upset and dizziness caused by this medicine. It is best to avoid alcohol while taking this medicine, especially if you have a urinary tract infection, because alcohol can dehydrate you and irritate the bladder.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Known allergy to nitrofurantoin or any component of this medicine","Significant kidney impairment with reduced creatinine clearance","Pregnancy at term (38 to 42 weeks)","Infants under one month of age","Glucose-6-phosphate dehydrogenase deficiency","History of cholestatic jaundice or liver injury due to nitrofurantoin"]
⚠️ Warnings & Precautions
["Do not crush, chew, or split the sustained-release tablet; swallow it whole with water.","Take this medicine with food to improve absorption and reduce stomach upset.","Avoid magnesium trisilicate antacids within two hours of this medicine.","Use with caution in people with anemia, diabetes, or nerve disorders.","Long-term use requires monitoring for lung, liver, nerve, and blood side effects.","Stop this medicine and seek medical help if you develop shortness of breath, persistent cough, numbness, tingling, or yellowing of the eyes or skin.","Do not use this medicine for infections outside the urinary tract.","Complete the full course prescribed by your clinician even if symptoms improve early."]
🤱 Lactation Safety
This medicine passes into breast milk in small amounts. It is generally considered compatible with breastfeeding, but it should be avoided in mothers with glucose-6-phosphate dehydrogenase deficiency and in infants under one month of age or with glucose-6-phosphate dehydrogenase deficiency. Consult your doctor before breastfeeding while taking this medicine.
💊 Overdose Management
Overdose of this medicine can cause nausea, vomiting, and diarrhea. In severe cases, it may lead to stomach irritation or other serious effects. If you suspect an overdose, contact your doctor or a poison control center immediately. Treatment is supportive and may include stomach emptying if the overdose was recent. Do not try to treat an overdose at home.
⏰ Missed Dose
If you miss a dose of this medicine, take it as soon as you remember if less than half the dosing interval has passed. If more than half the dosing interval has passed, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for a missed one.
Additional Safety Advice
Take this medicine exactly as prescribed by your clinician and do not adjust the dose on your own. Swallow the sustained-release tablet whole with a full glass of water; do not crush, chew, or split it, because doing so can release the entire dose at once and increase side effects. Taking this medicine with food improves absorption and reduces stomach upset. Drink plenty of water throughout the day to help flush the urinary tract and support the medicine's action. Avoid taking antacids that contain magnesium trisilicate within two hours of this medicine, as they can reduce its effectiveness. Do not use this medicine to treat any infection other than the one for which it was prescribed. If you have kidney problems, liver problems, anemia, diabetes, or a nerve disorder, tell your doctor before starting this medicine. Do not share this medicine with anyone else, even if they have similar symptoms.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Older adults may need a lower dose of this medicine because kidney function often declines with age. Kidney function should be checked before and during treatment. Older adults are also at higher risk of peripheral neuropathy and lung reactions with long-term use. Report any numbness, tingling, cough, or breathlessness promptly. Dose must be individualized by a qualified clinician.
🤰 Pregnancy Planning (TTC)
If you are planning pregnancy, discuss this medicine with your doctor before conception. This medicine may be used in pregnancy for susceptible urinary tract infections under medical supervision, but it is avoided near term and in women with glucose-6-phosphate dehydrogenase deficiency. Your doctor will weigh the benefits and risks for your specific situation.
🏥 Post-Surgery Considerations
After surgery, this medicine may be used to prevent or treat urinary tract infections, especially if you have a urinary catheter. Inform your surgeon and anesthesiologist about all medicines you are taking. Follow your doctor's instructions on when to resume this medicine after surgery. Monitor for signs of infection and report them promptly.
🦷 Dental Procedures
Inform your dentist that you are taking this medicine before any dental procedure. This medicine does not usually interfere with dental procedures, but your dentist may need to know about it, especially if you are taking other medicines or have a history of allergies. Continue taking this medicine as prescribed unless your doctor advises otherwise.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
This medicine may cause dizziness in some people. Avoid strenuous exercise or activities that require balance if you feel dizzy. Gentle walking and light activity are usually fine. If you have peripheral neuropathy symptoms such as numbness or tingling, avoid activities that could cause injury to your feet and consult your doctor.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause dizziness or headache in some people. Avoid driving or operating heavy machinery if you feel dizzy or unwell. Most people can continue their usual work activities while taking this medicine. If your work involves heavy physical exertion, take breaks and stay hydrated. Inform your employer if you need to take time off for rest during the infection.
🛑 When to Stop This Medicine
Stop this medicine only after completing the full course prescribed by your clinician, unless your doctor tells you to stop earlier. Seek immediate medical advice and stop the medicine if you develop signs of a serious reaction such as shortness of breath, persistent cough, numbness or tingling, yellowing of the eyes or skin, severe rash, or swelling of the face, lips, or throat. Do not stop the medicine on your own before completing the course, as this can lead to recurrence of infection and bacterial resistance.
📅 Long-Term Use Effects
Long-term use of this medicine, especially for prevention of recurrent urinary tract infections, requires regular monitoring for lung reactions, peripheral neuropathy, liver injury, and blood disorders. The risk of these serious effects increases with prolonged use, particularly in older adults and people with kidney impairment. Your doctor may check your kidney and liver function periodically. Report any new cough, breathlessness, numbness, tingling, or unusual tiredness promptly. Long-term use should be reviewed regularly to ensure it is still necessary.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Drinking plenty of water helps flush bacteria from the urinary tract and can complement antibiotic treatment.
Evidence: Well-establishedSome studies suggest cranberry products may help prevent recurrent urinary tract infections, but evidence is mixed.
Evidence: LimitedProbiotics may help restore healthy gut and vaginal flora, especially during and after antibiotic use.
Evidence: LimitedProper genital hygiene and urinating after intercourse can help reduce the risk of urinary tract infections.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
This medicine may inactivate the live typhoid vaccine and reduce its effectiveness. Complete this medicine course before receiving the live typhoid vaccine, or follow your doctor's advice on timing. Other vaccines are generally not affected, but always inform your healthcare provider about all medicines you are taking before vaccination.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✅ DO
Keep out of reach of children
❌ DON'T
Do not use after the expiry date
✈️ Traveling with This Medicine
Carry this medicine in its original packaging with the prescription label visible. Bring a copy of your prescription or a letter from your doctor, especially for international travel. Store it at room temperature and keep it away from direct sunlight and moisture. If you are crossing time zones, continue taking this medicine at the same intervals as prescribed; you may need to adjust the timing gradually. Do not pack it in checked luggage; keep it in your carry-on bag. Check customs rules for carrying prescription medicines in your destination country.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: This medicine begins to act against bacteria within a few hours, but noticeable relief of urinary symptoms usually takes one to two days. Complete the full course prescribed by your clinician.
A: Yes, this medicine should be taken with food. Taking it with food improves absorption and reduces stomach upset.
A: No. This is a sustained-release tablet and must be swallowed whole with water. Crushing, chewing, or splitting it can release the entire dose at once and increase side effects.
A: If less than half the dosing interval has passed, take the missed dose as soon as you remember. If more than half has passed, skip it and continue with your regular schedule. Do not double dose.
A: This medicine may be used in pregnancy for susceptible urinary tract infections under medical supervision, but it is avoided near term and in women with glucose-6-phosphate dehydrogenase deficiency. Consult your doctor.
A: It is best to avoid alcohol while taking this medicine, as it may worsen stomach upset and dizziness and can dehydrate you.
A: The duration depends on the indication. For acute urinary tract infection, it is usually 5 to 7 days. For prevention, it may be several weeks or months. Follow your clinician's prescription exactly.
A: This medicine is excreted by the kidneys and should be avoided in significant kidney impairment. Your doctor may check your kidney function before and during treatment.
🤔 Common Patient Concerns
🛑 Myths vs. Facts
- Myth: This medicine can be used for any type of infection.
Fact: This medicine is only effective for urinary tract infections caused by susceptible bacteria. It does not treat infections outside the urinary tract or viral infections. - Myth: You can stop this medicine as soon as you feel better.
Fact: You must complete the full course prescribed by your clinician, even if symptoms improve early, to prevent the infection from returning and to reduce the risk of bacterial resistance. - Myth: This medicine is safe for everyone with a urinary tract infection.
Fact: This medicine should not be used by people with significant kidney impairment, pregnant women at term, infants under one month of age, or people with glucose-6-phosphate dehydrogenase deficiency. - Myth: Crushing or splitting the tablet is fine if it is hard to swallow.
Fact: The sustained-release tablet must be swallowed whole. Crushing, chewing, or splitting it can release the entire dose at once and increase side effects.
🔄 Alternative Options
Generic Alternatives
- Nitrofurantoin sustained-release tablet
Brand Alternatives
- Nitfuin 100mg Tablet SR