Nimcef-az Tablet: Comprehensive Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Severe allergic reaction (difficulty breathing, swelling of face or throat)
- Persistent diarrhea with fever or abdominal cramps
- Yellowing of skin or eyes
- Severe abdominal pain
- Unusual bleeding or bruising
- Irregular heartbeat or palpitations
If experiencing severe symptoms, call emergency services immediately.
What is nimcef-az tablet used for?
This medicine is a combination antibiotic containing cefixime and azithromycin. It is used to treat various bacterial infections such as typhoid, pneumonia, and urinary tract infections. It works by killing bacteria and stopping their growth. Always take it as prescribed by your doctor.
- Generic Name: Information coming soon
- Manufacturer: Multiple manufacturers
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 nimcef-az tablet के बारे में (Hindi Summary)
उपयोग: यह दवा सेफिक्सिम और एज़िथ्रोमाइसिन का संयोजन है, जिसका उपयोग विभिन्न जीवाणु संक्रमणों जैसे टाइफाइड, निमोनिया, मूत्र मार्ग संक्रमण और क्लैमाइडिया के इलाज के लिए किया जाता है। यह दवा बैक्टीरिया को मारकर या उनकी वृद्धि को रोककर काम करती है। इसे डॉक्टर के निर्देशानुसार ही लें।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में दस्त, जी मिचलाना, पेट दर्द और सिरदर्द शामिल हैं। गंभीर दुष्प्रभाव दुर्लभ हैं, लेकिन एलर्जी, गंभीर दस्त, या यकृत की समस्या हो सकती है। यदि कोई असामान्य लक्षण दिखे तो तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: इस दवा को लेने से पहले अपने डॉक्टर को अपनी सभी एलर्जी और चिकित्सीय स्थितियों के बारे में बताएं। गुर्दे या यकृत की बीमारी, हृदय की समस्या, या मायस्थेनिया ग्रेविस हो तो सावधानी बरतें। एंटासिड के साथ इस दवा को न लें, कम से कम 2 घंटे का अंतराल रखें। शराब का सेवन न करें। गर्भावस्था या स्तनपान के दौरान डॉक्टर से परामर्श लें।
💊 nimcef-az tablet Uses & Benefits
[{"condition":"Typhoid fever","description":"Used to treat enteric fever caused by Salmonella typhi, often as a combination therapy to cover resistant strains.","evidence":"Well-established"},{"condition":"Community-acquired pneumonia","description":"Effective against common respiratory pathogens including Streptococcus pneumoniae and Haemophilus influenzae.","evidence":"Well-established"},{"condition":"Acute exacerbation of chronic bronchitis","description":"Helps reduce bacterial load and symptoms in patients with underlying chronic lung disease.","evidence":"Well-established"},{"condition":"Urinary tract infections","description":"Covers common uropathogens such as Escherichia coli and Klebsiella species.","evidence":"Well-established"},{"condition":"Uncomplicated gonorrhea","description":"Azithromycin component is effective against Neisseria gonorrhoeae, but resistance patterns should be considered.","evidence":"Moderate"},{"condition":"Chlamydia trachomatis infection","description":"Azithromycin is a first-line treatment for chlamydial urethritis and cervicitis.","evidence":"Well-established"}]
Off-label uses: [{"condition":"Helicobacter pylori eradication","description":"Sometimes included in combination regimens for H. pylori, though not a standard first-line choice.","evidence":"Limited"},{"condition":"Acne vulgaris","description":"Azithromycin has been used off-label for inflammatory acne, but not routinely recommended.","evidence":"Limited"}]
Primary treatment for: Bacterial infections
Also treats: Typhoid fever, Community-acquired pneumonia, Urinary tract infections, Chlamydia infection
📋 Drug Information
| Generic Name(s) | Information coming soon |
| Brand Name | nimcef-az tablet |
| Manufacturer | Multiple manufacturers |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | ANTI INFECTIVES |
| Action Class | |
| Route of Administration | Oral |
| Storage | Store at room temperature (15-30°C) in a dry place, away from direct sunlight. Keep in the original container. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine combines two antibiotics with distinct mechanisms. Cefixime, a third-generation cephalosporin, inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins, leading to cell lysis and death. Azithromycin, a macrolide antibiotic, binds to the 50S ribosomal subunit of susceptible bacteria, inhibiting protein synthesis and thereby stopping bacterial growth. The combination provides a broader spectrum of activity and may offer synergistic effects against certain pathogens.
Mechanism Steps
💡 How to Take nimcef-az tablet
Strength: Each tablet contains cefixime 200 mg and azithromycin 250 mg.
Dosage Information
| Adult Dosage | The usual adult dose of this medicine is one tablet taken orally once or twice daily, depending on the severity of the infection and the prescribing doctor's judgment. The duration of treatment varies by indication, typically 5 to 14 days. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients may require dose adjustment based on renal function. Use with caution and monitor for side effects. |
| Renal Impairment | In patients with renal impairment, dose adjustment of cefixime may be necessary. Azithromycin generally does not require adjustment. Consult your doctor. |
| Hepatic Impairment | No specific dose adjustment is established for hepatic impairment. Use with caution and monitor liver function. |
| Maximum Daily Dose | The maximum recommended daily dose is 400 mg of cefixime and 500 mg of azithromycin. Do not exceed the prescribed dose. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of nimcef-az tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | |
| Ergotamine | Major | |
| Digoxin | Major | |
| Antacids | Moderate | |
| Carbamazepine | Moderate | |
| Cyclosporine | Moderate | |
| Oral contraceptives | Minor | |
| Theophylline | Minor |
🚨 Major Interactions
- Warfarin
- Ergotamine
- Digoxin
⚡ Moderate Interactions
- Antacids
- Carbamazepine
- Cyclosporine
🍷 Alcohol Interaction
Alcohol may increase the risk of liver toxicity and gastrointestinal side effects. It is advisable to avoid alcohol while taking this medicine.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Hypersensitivity to cefixime, azithromycin, or any component of the formulation","History of cholestatic jaundice/hepatic dysfunction associated with prior azithromycin use","Concomitant use with ergotamine"]
⚠️ Warnings & Precautions
["Use with caution in patients with renal impairment; dose adjustment may be required.","Use with caution in patients with hepatic impairment.","May cause dizziness; avoid driving or operating machinery until you know how it affects you.","Avoid alcohol during treatment.","Complete the full course as prescribed to prevent resistance.","Inform your doctor if you develop diarrhea, as it may be a sign of C. difficile infection."]
🤱 Lactation Safety
Both cefixime and azithromycin are excreted in breast milk in small amounts. They are generally considered compatible with breastfeeding, but consult your doctor.
💊 Overdose Management
Overdose may cause severe nausea, vomiting, diarrhea, and abdominal pain. Seek immediate medical attention. Treatment is symptomatic and supportive. Hemodialysis does not effectively remove cefixime or azithromycin from the blood.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose.
Additional Safety Advice
Before taking this medicine, inform your doctor if you are allergic to penicillins, cephalosporins, or macrolide antibiotics. Provide a complete medical history, especially of kidney or liver disease, heart rhythm disorders, and myasthenia gravis. This medicine may interact with blood thinners, antacids, and certain cholesterol-lowering drugs. Avoid taking antacids within two hours of this medicine, as they can reduce its absorption. Do not skip doses or stop treatment early, even if you feel better, to prevent antibiotic resistance. Take this medicine with food to reduce stomach upset. Stay well hydrated. Avoid alcohol during treatment. If you are pregnant or breastfeeding, consult your doctor before use. This medicine may cause dizziness; avoid driving or operating machinery until you know how it affects you.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients may be more susceptible to side effects, especially renal and cardiac effects. Dose adjustment may be needed based on kidney function. Monitor closely.
🤰 Pregnancy Planning (TTC)
If you are planning pregnancy, consult your doctor before taking this medicine. Both components are generally considered safe in pregnancy, but use only if clearly needed.
🏥 Post-Surgery Considerations
Inform your surgeon if you are taking this medicine before surgery. It may interact with other medications used during surgery.
🦷 Dental Procedures
Inform your dentist if you are taking this medicine. It may affect bleeding risk and interact with other medications.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
If you experience dizziness or fatigue, avoid strenuous exercise until you feel better. Light activity is generally safe.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause dizziness or fatigue. Avoid driving or operating heavy machinery until you know how it affects you. Most people can continue their daily activities with caution.
🛑 When to Stop This Medicine
Do not stop this medicine without consulting your doctor, even if you feel better. Stopping early can lead to treatment failure and antibiotic resistance. If you experience severe side effects, contact your doctor immediately.
📅 Long-Term Use Effects
Long-term use of this medicine may lead to antibiotic resistance, fungal superinfections, and rarely, liver or kidney problems. Regular monitoring may be required if used for prolonged periods. Always consult your doctor before extending treatment.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Can help prevent antibiotic-associated diarrhea.
Evidence: ModerateFor viral infections, rest and fluids are recommended instead of antibiotics.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
Antibiotics may reduce the efficacy of live bacterial vaccines like typhoid vaccine. Consult your doctor about vaccination timing.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
Carry this medicine in its original packaging with a copy of your prescription. Store at room temperature and protect from direct sunlight. If traveling across time zones, adjust dosing times gradually. Check customs regulations for carrying antibiotics.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: You may start feeling better within 2-3 days, but you must complete the full course as prescribed.
A: Yes, you can take it with or without food. Taking it with food may reduce stomach upset.
A: Take it as soon as you remember. If it's almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose.
🤔 Common Patient Concerns
🛑 Myths vs. Facts
- Myth: This medicine can cure viral infections like the common cold.
Fact: This medicine is effective only against bacterial infections. It does not treat viral infections. - Myth: You can stop taking this medicine once you feel better.
Fact: You must complete the full course as prescribed to prevent the infection from returning and to avoid antibiotic resistance.
🔄 Alternative Options
Generic Alternatives
- Cefixime 200 mg + Azithromycin 250 mg tablet