Nilstat 500mg Injection: Complete Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Difficulty breathing or swelling of face, lips, or throat
- Severe rash or hives
- Decreased urine output or swelling in legs
- Unusual bleeding or bruising
- Severe abdominal pain or bloody diarrhea
- Chest pain or irregular heartbeat
- Yellowing of skin or eyes
If experiencing severe symptoms, call emergency services immediately.
What is nilstat 500mg injection used for?
This medicine is a prescription antifungal injection used in hospitals to treat serious fungal infections like invasive candidiasis. It works by breaking down the fungal cell membrane. It must be given by a healthcare professional.
- Generic Name: Information coming soon
- Manufacturer: Multiple manufacturers
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 nilstat 500mg injection के बारे में (Hindi Summary)
उपयोग: यह दवा एक एंटीफंगल इंजेक्शन है जिसका उपयोग अस्पताल में गंभीर फंगल संक्रमणों जैसे कैंडिडा संक्रमण के इलाज के लिए किया जाता है। यह फंगस की कोशिका भित्ति को नष्ट करके उसे मार देती है। यह केवल डॉक्टर या नर्स द्वारा नस के माध्यम से दी जाती है।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में मतली, उल्टी, दस्त, पेट दर्द और इंजेक्शन की जगह पर दर्द शामिल हैं। गंभीर दुष्प्रभावों में एलर्जी, सांस लेने में कठिनाई, गुर्दे की समस्या और रक्त विकार हो सकते हैं। कोई भी असामान्य लक्षण दिखने पर तुरंत डॉक्टर को बताएं।
सुरक्षा सलाह: यह दवा केवल अस्पताल में डॉक्टर या नर्स द्वारा दी जानी चाहिए। इसे घर पर स्वयं न लगाएं। इससे पहले कि आपको यह इंजेक्शन दिया जाए, अपने डॉक्टर को अपनी सभी दवाओं और एलर्जी के बारे में बताएं। इलाज के दौरान शराब न पिएं। गुर्दे की कार्यप्रणाली की निगरानी के लिए नियमित जांच कराएं।
💊 nilstat 500mg injection Uses & Benefits
[{"condition":"Invasive candidiasis","description":"Used for the treatment of serious systemic infections caused by Candida species, including candidemia and deep-seated candidal infections.","evidence":"Well-established"},{"condition":"Candidemia","description":"Used in hospitalized patients with Candida bloodstream infections when other antifungals are not suitable.","evidence":"Well-established"},{"condition":"Disseminated fungal infections","description":"May be used for disseminated fungal infections in immunocompromised patients.","evidence":"Limited"}]
Off-label uses: [{"condition":"Aspergillosis","description":"Sometimes considered for invasive aspergillosis in patients who cannot tolerate other antifungals, though evidence is limited.","evidence":"Limited"}]
Primary treatment for: Invasive candidiasis
Also treats: Candidemia, Disseminated fungal infections
📋 Drug Information
| Generic Name(s) | Information coming soon |
| Brand Name | nilstat 500mg injection |
| Manufacturer | Multiple manufacturers |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | ANTI INFECTIVES |
| Action Class | Cephalosporins: 3 generation |
| Route of Administration | Parenteral (intravenous) |
| Storage | Store in a refrigerator at 2-8°C. Do not freeze. Protect from light. Keep in the original container. |
| Shelf Life | Not established from the available information. Refer to the product packaging for the expiration date. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
Nystatin binds to ergosterol, a key component of the fungal cell membrane. This binding creates pores or channels in the membrane, leading to leakage of intracellular ions and molecules, which results in fungal cell death. Because human cell membranes contain cholesterol rather than ergosterol, nystatin has selective toxicity for fungi.
Mechanism Steps
💡 How to Take nilstat 500mg injection
Strength: 500 mg injection
Dosage Information
| Adult Dosage | The dose of this medicine is determined by your doctor based on the type and severity of the fungal infection, your kidney function, and your overall health. It is given as an intravenous infusion over a period of time in a hospital setting. The usual adult dose ranges from 0.5 to 1.5 mg/kg per day, but this must be individualized by a qualified clinician. Do not attempt to self-administer. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients may have reduced kidney function and may require lower doses. Dose must be individualized by a qualified clinician. |
| Renal Impairment | Dose adjustment may be necessary in patients with kidney impairment. Your doctor will determine the appropriate dose based on your kidney function tests. |
| Hepatic Impairment | No specific dose adjustment is established for liver impairment. Use with caution and monitor liver function. |
| Maximum Daily Dose | Not established from the available information. The maximum dose should be determined by a qualified clinician. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of nilstat 500mg injection
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Aminoglycosides | Major | |
| Amphotericin B | Major | |
| Corticosteroids | Moderate | |
| Digoxin | Minor | |
| Warfarin | Minor |
🚨 Major Interactions
- Nephrotoxic drugs (e.g., aminoglycosides, amphotericin B)
- Neuromuscular blocking agents
⚡ Moderate Interactions
- Corticosteroids
- Digoxin
🍷 Alcohol Interaction
Avoid alcohol while receiving this medicine, as it may increase the risk of stomach upset, nausea, and liver problems.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Known hypersensitivity to nystatin or any component of the formulation","Not for use in patients with a history of severe allergic reactions to polyene antifungals"]
⚠️ Warnings & Precautions
["Administer only under medical supervision.","Use with caution in patients with kidney impairment.","Monitor for signs of allergic reactions during infusion.","Avoid concurrent use with other nephrotoxic drugs.","Inform your doctor if you are pregnant or breastfeeding."]
🤱 Lactation Safety
It is not known whether nystatin passes into breast milk when given intravenously. Consult your doctor before breastfeeding.
💊 Overdose Management
Overdose with this medicine is unlikely due to its administration by healthcare professionals. If overdose is suspected, treatment should be symptomatic and supportive. Contact a poison control center or emergency room immediately.
⏰ Missed Dose
Since this medicine is given by a healthcare professional in a hospital setting, missed doses are managed by your medical team. If you miss an appointment for your injection, contact your doctor as soon as possible to reschedule.
Additional Safety Advice
This medicine must only be given by a qualified healthcare professional in a hospital or clinic setting. Do not attempt to self-administer this injection. Before receiving this medicine, tell your doctor if you are allergic to nystatin or any other medicines. Inform your doctor about all prescription, over-the-counter, and herbal products you are taking, especially other antifungals, kidney-affecting drugs, and blood thinners. Your doctor may monitor your kidney function, blood counts, and liver function during treatment. If you are pregnant or breastfeeding, discuss the risks and benefits with your doctor. Avoid alcohol during treatment as it may worsen side effects. Report any signs of allergic reaction, such as rash, itching, swelling, or difficulty breathing, immediately.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients may have reduced kidney function and may require lower doses. Close monitoring is recommended.
🤰 Pregnancy Planning (TTC)
If you are planning pregnancy, discuss with your doctor. This medicine should be used during pregnancy only if clearly needed.
🏥 Post-Surgery Considerations
If you have surgery while on this medicine, inform your surgeon and anesthesiologist. They will manage your medication accordingly.
🦷 Dental Procedures
Inform your dentist if you are receiving this medicine. No specific precautions are established, but good hygiene is important.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Avoid strenuous exercise during treatment, especially if you feel weak or dizzy. Light activity may be okay, but consult your doctor first.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine is given in a hospital, so you may need to take time off work for treatment. You may feel tired or weak during treatment, so plan for rest.
🛑 When to Stop This Medicine
Do not stop this medicine without your doctor's advice. Stopping early may allow the infection to return. Your doctor will decide when to stop based on your progress.
📅 Long-Term Use Effects
Long-term use of this medicine may increase the risk of kidney damage and blood disorders. Regular monitoring of kidney function, liver function, and blood counts is recommended. The duration of treatment should be determined by your doctor based on your response and the type of infection.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Depending on the infection, other antifungals like fluconazole or amphotericin B may be used.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
No specific vaccine interactions are established. However, live vaccines should be avoided during treatment if you are immunocompromised. Consult your doctor.
📦 Storage Guide
✅ DO
Store in refrigerator at 2-8°C
❌ DON'T
Do not freeze
✅ DO
Keep in original container
❌ DON'T
Do not transfer to another container
✅ DO
Protect from light
❌ DON'T
Do not use if solution is discolored or contains particles
✈️ Traveling with This Medicine
This medicine is given in a hospital setting, so travel advice is not applicable. If you are traveling after treatment, carry a copy of your prescription and medical records. Store any remaining medication as directed by your doctor.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: Improvement in symptoms may be seen within a few days, but the full course must be completed as prescribed.
A: This medicine is given in a hospital setting. You should not drive immediately after receiving it, as you may feel dizzy or weak.
A: This medicine can affect kidney function. Your doctor will monitor your kidney function regularly.
🤔 Common Patient Concerns
🛑 Myths vs. Facts
- Myth: This medicine can be taken orally.
Fact: This medicine is an injection and must be given intravenously in a hospital setting. - Myth: This medicine is safe for self-administration.
Fact: It must only be administered by a qualified healthcare professional.