nilol tablet sr - Atenolol (50mg) + Nifedipine (20mg) medicine

Beta-nicardia Capsule Sr: Complete Medicine Guide

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🏭 Intas Pharmaceuticals Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Oct 29, 2026
🤰 Pregnancy Category This medicine is not recommended during pregnancy unless clearly needed. Both atenolol and nifedipine may affect the fetus. Consult your doctor for alternative options. 📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Well-established for hypertension and angina.
Reviewed by
SaathiMed Expert Panel | Oct 29, 2026
🩺
Medically Fact-Checked & Clinically Verified by SaathiMed Clinical Review Board
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026

When to Call Your Doctor IMMEDIATELY

  • Very slow heartbeat (less than 50 beats per minute)
  • Severe dizziness or fainting
  • Chest pain that worsens or is not relieved by rest
  • Shortness of breath or difficulty breathing
  • Swelling of face, lips, or throat
  • Yellowing of skin or eyes
  • Decreased urine output

If experiencing severe symptoms, call emergency services immediately.

What is nilol tablet sr used for?

This medicine is a combination of Atenolol and Nifedipine used to treat high blood pressure and prevent angina. It works by slowing the heart rate and relaxing blood vessels. It is taken once daily as prescribed by a doctor.

  • Generic Name: Atenolol (50mg) + Nifedipine (20mg)
  • Manufacturer: Intas Pharmaceuticals Ltd
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 nilol tablet sr के बारे में (Hindi Summary)

उपयोग: यह दवा उच्च रक्तचाप (हाइपरटेंशन) और एंजाइना (सीने में दर्द) के इलाज के लिए इस्तेमाल की जाती है। यह एटेनोलोल और निफेडिपिन का संयोजन है, जो हृदय की गति को धीमा करके और रक्त वाहिकाओं को आराम देकर रक्तचाप को कम करती है। इसे डॉक्टर के निर्देशानुसार ही लें।

साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में थकान, चक्कर आना, सिरदर्द, पैरों में सूजन और धड़कन धीमी होना शामिल हैं। गंभीर दुष्प्रभावों में बहुत धीमी धड़कन, बहुत कम रक्तचाप, और सांस लेने में कठिनाई हो सकती है। कोई भी गंभीर लक्षण होने पर तुरंत डॉक्टर से संपर्क करें।

सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। इसे अचानक बंद न करें, क्योंकि इससे एंजाइना या दिल का दौरा पड़ सकता है। शराब न पिएं। गाड़ी चलाने या मशीन चलाने से बचें जब तक आपको इसका असर पता न चल जाए। गर्भावस्था में इसका उपयोग न करें जब तक डॉक्टर सलाह न दें। नियमित रूप से रक्तचाप और हृदय गति की जांच कराएं।

💡 Did You Know? India is the largest provider of generic medicines globally, supplying over 50% of global vaccine demand.

💊 nilol tablet sr Uses & Benefits

[{"condition":"Hypertension","description":"Used to lower high blood pressure in adults when a single agent is insufficient.","evidence":"Well-established"},{"condition":"Angina pectoris","description":"Used to prevent chest pain episodes in patients with stable angina.","evidence":"Well-established"}]

Off-label uses: [{"condition":"Hypertensive urgency","description":"Sometimes used in specific clinical settings under close supervision.","evidence":"Limited"}]

Primary treatment for: Hypertension

Also treats: Angina pectoris

📋 Drug Information

Generic Name(s)Atenolol (50mg) + Nifedipine (20mg)
Brand Namenilol tablet sr
ManufacturerIntas Pharmaceuticals Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassCARDIAC
Action Class
Route of AdministrationOral
StorageStore at room temperature (15-30°C) in a dry place, away from direct sunlight. Keep in the original container.
Shelf Life24 months from the date of manufacture.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Take this medicine at the same time each day to maintain consistent blood levels.
2
Monitor your blood pressure and heart rate regularly and keep a log.
3
Do not stop this medicine abruptly; always consult your doctor before discontinuation.
4
Avoid alcohol as it can increase dizziness and low blood pressure.
5
Inform your doctor if you experience swelling in your ankles or feet.
6
Report any shortness of breath, unusual tiredness, or slow heartbeat immediately.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅
High blood pressure
This medicine is commonly prescribed for this.
Likely Use
✅
Chest pain (angina)
This medicine is used to prevent angina attacks.
Likely Use
❌
Fever
This medicine is not a primary fever reducer.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionAtenolol is rapidly but incompletely absorbed from the gastrointestinal tract, with an oral bioavailability of approximately 50%. Nifedipine is well absorbed, but the sustained-release formulation slows its absorption. Food may affect the absorption of both components.
DistributionAtenolol is hydrophilic and distributes mainly in extracellular fluid, with low protein binding. Nifedipine is highly lipophilic and distributes widely into tissues, including vascular smooth muscle.
Protein BindingAtenolol: approximately 3% bound to plasma proteins. Nifedipine: approximately 92-98% bound to plasma proteins.
MetabolismAtenolol is minimally metabolized in the liver. Nifedipine is extensively metabolized in the liver by cytochrome P450 3A4 enzymes to inactive metabolites.
Half-LifeAtenolol: approximately 6-7 hours. Nifedipine: approximately 2-5 hours for immediate-release, but the sustained-release formulation may have a longer apparent half-life.
ExcretionAtenolol is primarily excreted unchanged in the urine. Nifedipine metabolites are excreted mainly in the urine, with some in the feces.
BioavailabilityAtenolol: approximately 50%. Nifedipine: approximately 40-70% due to first-pass metabolism, but the sustained-release form may have different bioavailability.
Onset of ActionAtenolol: within 1 hour. Nifedipine: within 20-30 minutes for immediate-release, but the sustained-release form has a slower onset.
Peak Plasma TimeAtenolol: 2-4 hours. Nifedipine: 1-2 hours for immediate-release, but the sustained-release form may peak later.
Duration of ActionAtenolol: approximately 24 hours. Nifedipine: approximately 12-24 hours for sustained-release.

How It Works

This medicine combines two active ingredients with complementary actions. Atenolol selectively blocks beta-1 adrenergic receptors in the heart, reducing heart rate, contractility, and cardiac output, which lowers blood pressure and decreases myocardial oxygen demand. Nifedipine blocks L-type calcium channels in vascular smooth muscle, causing vasodilation and reduced peripheral resistance. The combined effect provides more effective blood pressure control and anti-anginal protection than either agent alone.

Mechanism Steps

1
Atenolol blocks beta-1 receptors: Atenolol binds to beta-1 adrenergic receptors in the heart, reducing the effects of adrenaline and noradrenaline.
2
Reduced cardiac output: This leads to a slower heart rate and reduced force of contraction, lowering cardiac output and blood pressure.
3
Nifedipine blocks calcium channels: Nifedipine inhibits calcium influx into vascular smooth muscle cells, causing relaxation and vasodilation.
4
Reduced peripheral resistance: Vasodilation decreases peripheral vascular resistance, further lowering blood pressure and improving blood flow.
5
Combined effect: The two mechanisms work together to provide effective blood pressure control and reduce angina episodes.

💡 How to Take nilol tablet sr

Strength: Sustained-release capsule containing Atenolol 50 mg and Nifedipine 20 mg.

1Take this medicine orally with a glass of water.
2Swallow the capsule whole; do not crush or chew.
3Take it at the same time each day, preferably in the morning.
4You may take it with or without food, but be consistent.
5Do not stop taking this medicine suddenly without consulting your doctor.

Dosage Information

Adult DosageThe usual adult dose is one capsule once daily, taken orally, preferably at the same time each day. The dose may be adjusted by your doctor based on your blood pressure response and tolerance. Do not exceed the prescribed dose. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageElderly patients may be more sensitive to the effects of this medicine. Start with a lower dose and monitor closely for hypotension and bradycardia. Dose must be individualized by a qualified clinician.
Renal ImpairmentAtenolol is excreted renally; dose adjustment is required in patients with renal impairment. Consult your doctor for appropriate dosing.
Hepatic ImpairmentNifedipine is metabolized in the liver; use with caution in patients with hepatic impairment. Dose adjustment may be needed. Consult your doctor.
Maximum Daily DoseThe maximum recommended daily dose is one capsule (Atenolol 50 mg + Nifedipine 20 mg) once daily. Do not exceed without medical advice.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With food
Take consistently
May reduce stomach upset and ensure consistent absorption.
Grapefruit
Avoid
May increase nifedipine levels and risk of side effects.

⏰ What to Do If You Miss a Dose

📌 Less than 12 hours have passed since the missed dose
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than 12 hours have passed since the missed dose
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of nilol tablet sr

✅ Common Side Effects

Fatigue (Common (5-10%))
Usually resolves with continued use. Consult doctor if persistent.
Dizziness (Common (5-10%))
Rise slowly from sitting or lying positions. Avoid driving if affected.
Headache (Common (5-10%))
May resolve on its own. Use paracetamol if needed, but consult doctor if severe.
Flushing (Common (5-10%))
Usually temporary. Stay hydrated and avoid alcohol.
Ankle swelling (Common (5-10%))
Elevate legs when resting. Consult doctor if severe or persistent.

🚨 Serious Side Effects

Severe bradycardia (Rare (<0.1%))
Seek immediate medical attention if you experience a very slow heartbeat, fainting, or severe dizziness.
Severe hypotension (Rare (<0.1%))
Seek immediate medical attention if you experience fainting, blurred vision, or confusion.
Worsening heart failure (Rare (<0.1%))
Report increased shortness of breath, swelling, or weight gain to your doctor promptly.
Bronchospasm (Rare (<0.1%))
Seek immediate medical attention if you develop wheezing or difficulty breathing.

⚠️ Rare Side Effects

Allergic reactions
Seek immediate medical attention if you notice rash, itching, swelling, or difficulty breathing.
Mood changes
Consult your doctor if you experience depression or unusual mood swings.
Sleep disturbances
Discuss with your doctor if sleep problems persist.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Verapamil Major
Clonidine Major
Ketoconazole Major
Digoxin Moderate
NSAIDs Moderate
Salbutamol Moderate
Antacids Minor
Grapefruit juice Minor

🚨 Major Interactions

  • Verapamil or diltiazem
  • Clonidine
  • CYP3A4 inhibitors (e.g., ketoconazole, ritonavir)

⚡ Moderate Interactions

  • Digoxin
  • NSAIDs
  • Beta-agonists (e.g., salbutamol)

🍷 Alcohol Interaction

Alcohol may increase the blood pressure-lowering effect of this medicine, leading to dizziness, fainting, and increased risk of falls. It is advisable to avoid alcohol while taking this medicine.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Severe asthma or COPD","Second- or third-degree heart block","Severe bradycardia","Cardiogenic shock","Severe hypotension","Pregnancy (unless advised by specialist)","Hypersensitivity to atenolol or nifedipine"]

⚠️ Warnings & Precautions

["Do not stop this medicine abruptly; taper gradually under medical supervision.","Use with caution in patients with diabetes, as it may mask hypoglycemia symptoms.","May worsen heart failure; monitor closely.","Use with caution in patients with peripheral vascular disease.","May cause dizziness; avoid driving or operating machinery until effects are known.","Avoid alcohol while taking this medicine.","Inform your doctor if you have kidney or liver problems."]

🤱 Lactation Safety

Atenolol and nifedipine are excreted in breast milk. Breastfeeding is not recommended while taking this medicine. Consult your doctor for safe alternatives.

💊 Overdose Management

Overdose may cause severe hypotension, bradycardia, heart failure, and shock. Seek immediate medical attention. Treatment is supportive and may include intravenous fluids, atropine, vasopressors, and glucagon. Hemodialysis may be considered for atenolol removal.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up.

Additional Safety Advice

General Safety

Take this medicine exactly as prescribed by your doctor. Do not stop taking it suddenly, as abrupt withdrawal of Atenolol can worsen angina or cause a heart attack. Avoid driving or operating heavy machinery until you know how this medicine affects you. Do not drink alcohol while taking this medicine, as it can increase dizziness and low blood pressure. Inform your doctor if you have asthma, diabetes, kidney problems, liver problems, or heart failure. Do not use this medicine during pregnancy unless specifically advised by your doctor. Keep all follow-up appointments for blood pressure and heart rate monitoring.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients are more prone to dizziness, falls, and electrolyte imbalances. Start with a lower dose and monitor closely. Regular follow-up is essential.

🤰 Pregnancy Planning (TTC)

This medicine is not recommended during pregnancy or when planning pregnancy. Consult your doctor to switch to a safer alternative before conception.

🏥 Post-Surgery Considerations

Inform your surgeon and anesthesiologist about this medicine before surgery. It may interact with anesthetic agents and affect blood pressure and heart rate during surgery.

🦷 Dental Procedures

Inform your dentist about this medicine before any dental procedure. It may cause dry mouth or affect blood pressure during the procedure. Local anesthetics with epinephrine should be used with caution.

💚 Lifestyle Tips for Better Results

🏃
Maintain a healthy weight to help control blood pressure.
🥗
Engage in regular physical activity as advised by your doctor.
😴
Reduce salt intake to help lower blood pressure.
💧
Avoid smoking and limit alcohol consumption.
🧘
Manage stress through relaxation techniques like yoga or meditation.
🌞
Get adequate sleep and follow a regular sleep schedule.

🏋️ Exercise Considerations

Avoid strenuous exercise initially as it may cause dizziness or fainting due to lowered blood pressure. Gradually increase activity as tolerated. Consult your doctor before starting any new exercise program.

🥗 Diet Recommendations

Follow a heart-healthy diet rich in fruits, vegetables, and whole grains.
Limit sodium intake to less than 2 grams per day.
Avoid grapefruit and grapefruit juice.
Include potassium-rich foods like bananas and spinach, unless advised otherwise.
Limit saturated fats and cholesterol.

💼 Impact on Daily Work & Life

This medicine may cause dizziness or fatigue, especially when starting treatment. Avoid driving or operating heavy machinery until you know how it affects you. It is usually safe to continue desk jobs, but take breaks if you feel dizzy.

🛑 When to Stop This Medicine

Do not stop this medicine without consulting your doctor. If you experience serious side effects or your doctor decides to change your treatment, they will provide a tapering schedule. Abrupt withdrawal can worsen angina or cause a heart attack.

📅 Long-Term Use Effects

Long-term use of this medicine may require regular monitoring of blood pressure, heart rate, and kidney function. It may also cause fluid retention and swelling. Periodic eye exams are recommended as nifedipine may rarely cause gum hyperplasia. Do not stop the medicine without medical advice.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Lifestyle modifications

Diet, exercise, and stress reduction can help manage blood pressure.

Evidence: Well-established
Other antihypertensive classes

ACE inhibitors, ARBs, or diuretics may be alternatives if this medicine is not suitable.

Evidence: Well-established

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

No specific vaccine interactions are known. However, inform your doctor about this medicine before receiving any vaccine.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

Carry this medicine in its original packaging with a copy of your prescription. Keep it in your hand luggage to avoid loss. Store at room temperature and protect from extreme heat or cold. If crossing time zones, consult your doctor about adjusting the timing of your dose. Check local customs regulations for carrying prescription medicines.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 55-year-old man with hypertension and angina
He was prescribed this medicine after his blood pressure remained high on a single drug. Within a few weeks, his blood pressure stabilized and angina episodes reduced. He experienced mild ankle swelling, which was managed by elevating his legs and reducing salt intake.
💡 Lesson: Combination therapy can be effective when single agents fail, but side effects should be reported and managed promptly.
👤 A 62-year-old woman with a history of asthma
She was started on this medicine but developed wheezing and shortness of breath. Her doctor discontinued it and switched to a different class of antihypertensive.
💡 Lesson: This medicine is not suitable for patients with asthma; alternative treatments should be considered.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: This medicine starts lowering blood pressure within a few hours, but full effects may take 1-2 weeks. It is important to take it regularly.

Q: Can I stop taking this medicine if I feel better?

A: No, you should not stop this medicine without consulting your doctor. Stopping suddenly can cause serious heart problems.

Q: What should I do if I miss a dose?

A: If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my kidney function?
  • Can I drive after taking this medicine?
  • Does it interact with my other blood pressure medicines?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?

🔄 Substitutes for nilol tablet sr

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: This medicine can be stopped once blood pressure is normal.
    Fact: High blood pressure often has no symptoms, and stopping this medicine suddenly can cause serious heart problems. Continue as prescribed.
  • Myth: This medicine is safe to take during pregnancy.
    Fact: This medicine is not recommended during pregnancy unless specifically advised by a doctor.

🔄 Alternative Options

Generic Alternatives

  • Atenolol + Nifedipine combination generics

Brand Alternatives

  • Beta-Nicardia Capsule SR

📊 Comparison with Similar Medicines

[{"medicine":"Amlodipine + Atenolol","difference":"Amlodipine is a longer-acting calcium channel blocker; may cause less reflex tachycardia."},{"medicine":"Metoprolol + Nifedipine","difference":"Metoprolol is beta-1 selective; may have different side effect profile."}]

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