Inderal La 80mg Tablet: Complete Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Very slow heart rate (below 50 beats per minute)
- Severe dizziness or fainting
- Difficulty breathing or wheezing
- Chest pain or worsening angina
- Swelling of feet or ankles
- Unusual weight gain
- Severe fatigue or weakness
If experiencing severe symptoms, call emergency services immediately.
What is nigrain 80mg tablet tr used for?
This medicine is a long-acting beta-blocker used to treat high blood pressure, angina, and to prevent migraines. It works by slowing the heart rate and reducing the heart's workload.
- Generic Name: Propranolol (80mg)
- Manufacturer: Torrent Pharmaceuticals Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 nigrain 80mg tablet tr के बारे में (Hindi Summary)
उपयोग: यह दवा उच्च रक्तचाप, एनजाइना (सीने में दर्द), और माइग्रेन को रोकने के लिए इस्तेमाल की जाती है। यह हृदय की गति को धीमा करके और हृदय पर दबाव कम करके काम करती है। यह केवल डॉक्टर के पर्चे पर ही मिलती है।
साइड इफेक्ट्स: आम दुष्प्रभावों में थकान, ठंडे हाथ-पैर, चक्कर आना, और नींद में गड़बड़ी शामिल हैं। गंभीर दुष्प्रभावों में बहुत धीमी हृदय गति, निम्न रक्तचाप, और सांस लेने में कठिनाई हो सकती है। किसी भी गंभीर लक्षण पर तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। इसे अचानक बंद न करें। अस्थमा, मधुमेह, या हृदय रोग होने पर डॉक्टर को बताएं। शरूर न करें। गाड़ी चलाते समय सावधानी बरतें।
💊 nigrain 80mg tablet tr Uses & Benefits
[{"condition":"Hypertension","description":"Lowers blood pressure by reducing heart rate and cardiac output.","evidence":"Well-established"},{"condition":"Angina pectoris","description":"Reduces frequency and severity of angina attacks by decreasing myocardial oxygen demand.","evidence":"Well-established"},{"condition":"Migraine prophylaxis","description":"Prevents migraine headaches by modulating vascular tone and neuronal activity.","evidence":"Well-established"},{"condition":"Essential tremor","description":"Reduces tremor amplitude by blocking peripheral beta-adrenergic receptors.","evidence":"Well-established"},{"condition":"Performance anxiety","description":"Controls symptoms like rapid heartbeat and trembling in situational anxiety.","evidence":"Limited"}]
Off-label uses: [{"condition":"Infantile hemangioma","description":"Sometimes prescribed off-label for severe infantile hemangiomas.","evidence":"Limited"},{"condition":"Thyrotoxicosis","description":"Used off-label to control symptoms of hyperthyroidism.","evidence":"Limited"}]
Primary treatment for: Hypertension
Also treats: Angina, Migraine, Essential tremor, Anxiety
📋 Drug Information
| Generic Name(s) | Propranolol (80mg) |
| Brand Name | nigrain 80mg tablet tr |
| Manufacturer | Torrent Pharmaceuticals Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | CARDIAC |
| Action Class | Beta blocker- Non selective |
| Route of Administration | Oral |
| Storage | Store at room temperature (15-30°C) in a dry place, away from direct sunlight. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine works by blocking beta-adrenergic receptors, primarily beta-1 and beta-2 receptors, in the heart, blood vessels, and other tissues. By blocking these receptors, it reduces the effects of adrenaline and noradrenaline, leading to a slower heart rate, decreased force of heart contraction, and reduced blood pressure. This reduces the heart's oxygen demand and helps control angina. In migraine prevention, it is thought to stabilize blood vessel tone and modulate neuronal activity.
Mechanism Steps
💡 How to Take nigrain 80mg tablet tr
Strength: Extended-release tablet, 80 mg
Dosage Information
| Adult Dosage | The usual adult dose for hypertension is 80 mg once daily, which may be increased to 120-160 mg once daily as needed. For angina, 80-160 mg once daily. For migraine prophylaxis, 80-240 mg once daily. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Start with lower doses in elderly patients due to increased sensitivity. Dose must be individualized by a qualified clinician. |
| Renal Impairment | No specific dosage adjustment is generally required, but use with caution in severe renal impairment. |
| Hepatic Impairment | Reduce dose in patients with hepatic impairment. Dose must be individualized by a qualified clinician. |
| Maximum Daily Dose | The maximum daily dose is 640 mg for immediate-release, but for this extended-release formulation, doses above 320 mg are rarely used. Individualize by clinician. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of nigrain 80mg tablet tr
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Verapamil | Major | |
| Digoxin | Major | |
| Clonidine | Major | |
| NSAIDs | Moderate | |
| Fluoxetine | Moderate | |
| Antacids | Minor |
🚨 Major Interactions
- Verapamil
- Digoxin
- Clonidine
⚡ Moderate Interactions
- NSAIDs
- CYP2D6 inhibitors (e.g., fluoxetine)
🍷 Alcohol Interaction
Alcohol may increase the blood pressure-lowering effect of this medicine and cause dizziness. Avoid alcohol while taking this medicine.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Asthma or severe COPD","Severe bradycardia","Second or third-degree heart block","Cardiogenic shock","Uncontrolled heart failure","Severe peripheral arterial disease"]
⚠️ Warnings & Precautions
["Do not stop suddenly.","May mask symptoms of hypoglycemia in diabetics.","May worsen symptoms of Raynaud's phenomenon.","Use with caution in patients with liver disease.","May cause depression."]
🤱 Lactation Safety
This medicine passes into breast milk in small amounts. Consult your doctor before breastfeeding.
💊 Overdose Management
Overdose can cause severe bradycardia, hypotension, heart failure, and bronchospasm. Seek immediate medical attention. Treatment is supportive and may include atropine, glucagon, and vasopressors.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose.
Additional Safety Advice
Always take this medicine exactly as prescribed. Do not stop taking it suddenly, as this can cause serious heart problems. Inform your doctor if you have asthma, diabetes, thyroid disease, or liver problems. Avoid alcohol while taking this medicine. Use caution when driving or operating machinery until you know how this medicine affects you. Keep all follow-up appointments and monitor your heart rate and blood pressure regularly.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients may be more sensitive to the effects of this medicine. Start with lower doses and monitor closely.
🤰 Pregnancy Planning (TTC)
Consult your doctor if you are planning pregnancy or are pregnant. This medicine may affect the fetus.
🏥 Post-Surgery Considerations
Inform your surgeon and anesthesiologist that you are taking this medicine. It may interact with anesthetic agents.
🦷 Dental Procedures
Inform your dentist that you are taking this medicine, as it may interact with certain dental anesthetics.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
This medicine may reduce your exercise tolerance and cause fatigue. Start slowly and monitor your heart rate during exercise.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
May cause dizziness or fatigue, affecting driving or operating machinery. Adjust tasks as needed until you know how it affects you.
🛑 When to Stop This Medicine
Do not stop this medicine without consulting your doctor. Abrupt withdrawal can worsen angina or cause a heart attack.
📅 Long-Term Use Effects
Long-term use may require periodic monitoring of heart rate, blood pressure, and cardiac function. It may also mask symptoms of hypoglycemia in diabetics. Regular follow-up with your doctor is essential.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Diet, exercise, and stress management can complement medicine.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
No specific vaccine interactions reported. Consult your doctor before any vaccination.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
Carry this medicine in its original packaging with a copy of your prescription. Store at room temperature and protect from direct sunlight. If traveling across time zones, consult your doctor about adjusting the dosing schedule. Keep enough supply for the entire trip.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: This medicine starts working within 1-2 hours, but full effects may take several weeks.
A: No, stopping suddenly can cause serious heart problems. Always consult your doctor.
🤔 Common Patient Concerns
🔄 Substitutes for nigrain 80mg tablet tr
View AllAlternative brands with exact same active ingredient:
-
inderal la 80mg tabletAbbott ₹10.53 77.8% CHEAPER
-
proparise 80mg tabletSunrise Remedies Pvt Ltd ₹20.63 56.6% CHEAPER
-
mizral 80mg tablet srRyon Pharma ₹22.50 52.7% CHEAPER
-
promotil 80mg tablet trTorrent Pharmaceuticals Ltd ₹40.00 15.8% CHEAPER
-
betasav 80mg capsule trSaviour Medisciences ₹40.31 15.2% CHEAPER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can be stopped once blood pressure is normal.
Fact: It should not be stopped suddenly as it can cause serious heart problems. Always consult your doctor before stopping. - Myth: This medicine is safe for everyone with high blood pressure.
Fact: It is not safe for people with asthma or certain heart conditions. Always consult a doctor.
🔄 Alternative Options
Generic Alternatives
- Propranolol extended-release tablets
Brand Alternatives
- Inderal LA 80mg Tablet