Nicorace 10mg Tablet: Complete Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Severe chest pain that does not go away with rest or nitroglycerin
- Fainting or severe dizziness
- Sudden swelling of face, lips, tongue, or throat
- Difficulty breathing
- Black or bloody stools
- Vomiting blood
- Non-healing sores in the mouth, genitals, or anus
- Yellowing of skin or eyes
- Decreased urine output
- Irregular or very fast heartbeat
If experiencing severe symptoms, call emergency services immediately.
What is nicorace 10mg tablet used for?
This medicine is a prescription oral tablet containing nicorandil 10 mg, used to prevent angina chest pain by relaxing blood vessels and improving blood flow to the heart. It is taken twice daily and should not be used for acute attacks.
- Generic Name: Information coming soon
- Manufacturer: Multiple manufacturers
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 nicorace 10mg tablet के बारे में (Hindi Summary)
उपयोग: यह दवा एंजाइना पेक्टोरिस (सीने में दर्द) को रोकने और इलाज करने के लिए इस्तेमाल की जाती है। यह रक्त वाहिकाओं को फैलाकर दिल तक रक्त का प्रवाह बढ़ाती है और दिल पर दबाव कम करती है। यह उन वयस्कों के लिए है जिन्हें अन्य दवाओं के बावजूद एंजाइना के दौरे पड़ते रहते हैं। यह दवा तीव्र एंजाइना के दौरे के लिए नहीं है।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में सिरदर्द, चक्कर आना, चेहरे पर लालिमा, मतली और उल्टी शामिल हैं। गंभीर दुष्प्रभाव दुर्लभ हैं लेकिन इनमें बहुत कम रक्तचाप, त्वचा पर अल्सर, और गंभीर एलर्जी प्रतिक्रिया शामिल हो सकती है। कोई भी असामान्य लक्षण दिखने पर तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। शराब का सेवन न करें क्योंकि इससे रक्तचाप कम हो सकता है और चक्कर आ सकते हैं। अचानक उठने से बचें। यदि आप गर्भवती हैं, गर्भधारण की योजना बना रही हैं या स्तनपान करा रही हैं तो डॉक्टर को बताएं। अन्य दवाओं के साथ इसका सेवन करने से पहले डॉक्टर से सलाह लें।
💊 nicorace 10mg tablet Uses & Benefits
[{"condition":"Chronic stable angina pectoris","description":"This medicine is used to reduce the frequency and severity of angina attacks in patients with chronic stable angina who remain symptomatic despite treatment with beta-blockers or calcium channel blockers.","evidence":"Well-established"},{"condition":"Unstable angina pectoris","description":"This medicine may be used in the management of unstable angina to reduce the risk of cardiac events, often in combination with other anti-anginal therapies.","evidence":"Moderate"},{"condition":"Vasospastic angina (Prinzmetal's angina)","description":"This medicine can help relieve coronary artery spasm and is sometimes used in patients with vasospastic angina.","evidence":"Limited"}]
Off-label uses: [{"condition":"Prevention of contrast-induced nephropathy","description":"Some studies suggest that nicorandil may help protect kidney function in patients undergoing procedures with contrast dye, but this is not a standard approved use.","evidence":"Limited"},{"condition":"Heart failure with preserved ejection fraction","description":"Nicorandil has been investigated for potential benefits in heart failure, but evidence is not sufficient for routine use.","evidence":"Limited"}]
Primary treatment for: Angina pectoris
Also treats: Coronary artery disease, Vasospastic angina
📋 Drug Information
| Generic Name(s) | Information coming soon |
| Brand Name | nicorace 10mg tablet |
| Manufacturer | Multiple manufacturers |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | CARDIAC |
| Action Class | Potassium channel opener |
| Route of Administration | Oral |
| Storage | Store at room temperature between 15°C and 30°C (59°F to 86°F). Keep in the original container, away from moisture and direct sunlight. Do not refrigerate. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine works by opening adenosine triphosphate-sensitive potassium channels in vascular smooth muscle cells, which leads to relaxation of blood vessels. It also has a nitrate-like effect that increases cyclic guanosine monophosphate levels, further promoting vasodilation. This dual action improves blood flow to the heart and reduces the heart's oxygen demand, helping to prevent angina attacks.
Mechanism Steps
💡 How to Take nicorace 10mg tablet
Strength: This medicine is available as an immediate-release oral tablet containing 10 mg of nicorandil.
Dosage Information
| Adult Dosage | The usual adult dose of this medicine is 10 mg to 20 mg taken twice daily, with or without food. The dose may be increased gradually based on your response and tolerance, up to a maximum of 40 mg twice daily. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients may be more sensitive to the blood pressure-lowering effects of this medicine. Start with a lower dose and monitor blood pressure closely. Dose must be individualized by a qualified clinician. |
| Renal Impairment | No specific dose adjustment is established for mild to moderate renal impairment. In severe renal impairment, use with caution and monitor closely. Dose must be individualized by a qualified clinician. |
| Hepatic Impairment | No specific dose adjustment is established for mild to moderate hepatic impairment. In severe hepatic impairment, use is contraindicated. Dose must be individualized by a qualified clinician. |
| Maximum Daily Dose | The maximum recommended daily dose is 80 mg (40 mg twice daily). |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of nicorace 10mg tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Sildenafil | Major | |
| Nitroglycerin | Major | |
| Riociguat | Major | |
| Alcohol | Moderate | |
| Amlodipine | Moderate | |
| Metoprolol | Moderate | |
| Furosemide | Moderate | |
| Ibuprofen | Minor | |
| Grapefruit juice | Minor | |
| Aspirin | Minor |
🚨 Major Interactions
- Phosphodiesterase-5 inhibitors (e.g., sildenafil, tadalafil)
- Nitrates (e.g., nitroglycerin, isosorbide mononitrate)
- Riociguat
⚡ Moderate Interactions
- Alcohol
- Antihypertensives (e.g., ACE inhibitors, beta-blockers)
- Diuretics
🍷 Alcohol Interaction
Alcohol can increase the blood pressure-lowering effect of this medicine, leading to dizziness, fainting, and increased risk of falls. It is advisable to avoid alcohol or limit its consumption while taking this medicine.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Known allergy to nicorandil or any component of the tablet","Cardiogenic shock","Severe hypotension (low blood pressure)","Left ventricular failure with low filling pressure","Concomitant use with phosphodiesterase-5 inhibitors (e.g., sildenafil)","Concomitant use with riociguat","Severe dehydration","Severe liver disease"]
⚠️ Warnings & Precautions
["This medicine can cause severe low blood pressure, especially when standing up. Rise slowly.","Avoid alcohol while taking this medicine.","Do not use this medicine to treat an acute angina attack. Use a fast-acting nitrate for that.","Report any non-healing ulcers, especially in the mouth, genitals, or anus.","Use with caution in elderly patients and those with kidney or liver disease.","Inform your doctor if you are pregnant, planning pregnancy, or breastfeeding.","Do not stop this medicine abruptly without consulting your doctor."]
🤱 Lactation Safety
This medicine is excreted in breast milk in small amounts. It is not known if it is safe for the baby. Consult your doctor before breastfeeding while taking this medicine.
💊 Overdose Management
Overdose can cause severe hypotension, dizziness, and fainting. If you suspect an overdose, seek emergency medical attention immediately. Treatment is supportive and symptomatic, including measures to raise blood pressure and maintain vital functions.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for a missed one.
Additional Safety Advice
Take this medicine exactly as prescribed by your doctor. Do not change the dose or stop taking it without medical advice. Avoid alcohol while taking this medicine because it can increase the risk of low blood pressure and dizziness. Stand up slowly from a sitting or lying position to prevent dizziness. Inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding. Keep all your medical appointments and tell your doctor about all other medicines you are taking, especially those for erectile dysfunction, as the combination can cause a dangerous drop in blood pressure. Store this medicine in its original packaging at room temperature, away from moisture and direct sunlight.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients are more sensitive to the blood pressure-lowering effects of this medicine. Start with a lower dose and monitor blood pressure regularly. Watch for dizziness and falls.
🤰 Pregnancy Planning (TTC)
If you are planning pregnancy, consult your doctor before taking this medicine. The safety of this medicine during pregnancy is not well established. Your doctor may switch you to a safer alternative.
🏥 Post-Surgery Considerations
Inform your surgeon and anesthesiologist that you are taking this medicine before any surgery. It may need to be stopped temporarily, especially before procedures that can cause hypotension.
🦷 Dental Procedures
Inform your dentist that you are taking this medicine. It may cause low blood pressure during dental procedures. Your dentist may take precautions.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Moderate exercise is beneficial, but avoid strenuous activities that trigger angina. Always warm up and cool down. If you experience chest pain during exercise, stop immediately and rest. Consult your doctor before starting any new exercise program.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause dizziness or low blood pressure, which can affect your ability to drive or operate machinery. Avoid driving until you know how this medicine affects you. Take caution when standing up quickly. Most people can continue their daily activities with appropriate precautions.
🛑 When to Stop This Medicine
Do not stop this medicine without consulting your doctor. If you experience severe side effects such as fainting, severe dizziness, or signs of an allergic reaction, seek immediate medical attention. Your doctor may adjust the dose or switch to another medicine.
📅 Long-Term Use Effects
Long-term use of this medicine is generally well tolerated. However, regular monitoring of blood pressure, heart rate, and symptoms is advised. Rarely, it can cause ulcerations in the skin, mouth, or gastrointestinal tract. Liver and kidney function may need periodic checks. Do not stop the medicine without medical advice.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Heart-healthy diet, regular exercise, smoking cessation, and stress management can complement medicine for angina.
Evidence: Well-establishedAngioplasty or bypass surgery may be considered for severe coronary artery disease.
Evidence: Well-establishedSupervised exercise and education programs can improve heart health and reduce angina.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
No specific vaccine interactions are established. However, consult your doctor before receiving any vaccine while on this medicine.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
Carry this medicine in its original packaging with a copy of your prescription. Keep it in your hand luggage to avoid loss. Store at room temperature and protect from moisture. If traveling across time zones, adjust dosing times gradually in consultation with your doctor. Check customs regulations for carrying prescription medicines.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: This medicine starts working within 30 minutes, but its full benefits in reducing angina attacks may take a few days to weeks.
A: Yes, you can take it with or without food. Taking it with food may help reduce stomach upset.
A: If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double dose.
A: The safety of this medicine during pregnancy is not well established. Consult your doctor before taking it if you are pregnant or planning pregnancy.
A: No, do not stop this medicine without consulting your doctor, as it may worsen your angina.
🤔 Common Patient Concerns
🛑 Myths vs. Facts
- Myth: This medicine can be used to relieve an acute angina attack.
Fact: This medicine is for prevention of angina attacks, not for immediate relief. Use a fast-acting nitrate for acute attacks. - Myth: This medicine is safe to take with erectile dysfunction medicines.
Fact: Combining this medicine with erectile dysfunction medicines can cause a dangerous drop in blood pressure and is contraindicated. - Myth: You can stop taking this medicine once you feel better.
Fact: Do not stop this medicine without consulting your doctor, as it may worsen your condition.
🔄 Alternative Options
Generic Alternatives
- Nicorandil 10 mg tablet
Brand Alternatives
- Nicorace 10mg Tablet