Enteegee 25mg Injection (Nitroglycerin): Comprehensive Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Severe chest pain unrelieved by rest or other medications
- Sudden severe headache with confusion or vision changes
- Fainting or loss of consciousness
- Bluish discoloration of lips, skin, or nails
- Difficulty breathing or shortness of breath
- Rapid or irregular heartbeat
- Swelling of face, lips, or throat
If experiencing severe symptoms, call emergency services immediately.
What is ng-care 25mg powder for injection used for?
This medicine is a nitroglycerin injection used to treat acute angina, heart failure, and hypertensive emergencies. It works by dilating blood vessels, reducing the heart's workload. It is given intravenously under medical supervision.
- Generic Name: Nitroglycerin (25mg)
- Manufacturer: Sympar Life Sciences
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 ng-care 25mg powder for injection के बारे में (Hindi Summary)
उपयोग: यह दवा नाइट्रोग्लिसरीन का इंजेक्शन है, जिसका उपयोग तीव्र एनजाइना, दिल की विफलता और उच्च रक्तचाप की आपात स्थिति में किया जाता है। यह रक्त वाहिकाओं को फैलाकर दिल पर दबाव कम करती है। यह केवल अस्पताल में डॉक्टर की देखरेख में दी जाती है।
साइड इफेक्ट्स: आम दुष्प्रभावों में सिरदर्द, चक्कर आना, चेहरे पर लालिमा और कम रक्तचाप शामिल हैं। गंभीर दुष्प्रभावों में गंभीर निम्न रक्तचाप, धड़कन तेज होना और मेथेमोग्लोबिनेमिया हो सकता है। किसी भी असामान्य लक्षण पर तुरंत डॉक्टर को बताएं।
सुरक्षा सलाह: यह दवा केवल योग्य स्वास्थ्यकर्मी द्वारा निगरानी में दी जानी चाहिए। सिल्डेनाफिल या टैडालाफिल जैसी दवाओं के साथ इसका उपयोग बिल्कुल न करें। उपचार के दौरान शराब न पिएं। बिना डॉक्टर की सलाह के इंजेक्शन बंद न करें।
💊 ng-care 25mg powder for injection Uses & Benefits
[{"condition":"Acute angina pectoris","description":"This medicine is used to relieve acute attacks of angina by dilating coronary arteries and reducing cardiac workload.","evidence":"Well-established"},{"condition":"Acute heart failure","description":"It reduces preload and afterload, improving symptoms in acute decompensated heart failure.","evidence":"Well-established"},{"condition":"Hypertensive emergencies","description":"Used to rapidly lower blood pressure in hypertensive crises, especially during surgery.","evidence":"Well-established"},{"condition":"Controlled hypotension during surgery","description":"Induces deliberate hypotension to reduce bleeding during certain surgical procedures.","evidence":"Well-established"},{"condition":"Acute myocardial infarction","description":"May be used to reduce myocardial oxygen demand and improve coronary blood flow in selected patients.","evidence":"Moderate"}]
Off-label uses: [{"condition":"Esophageal spasm","description":"Sometimes used to relieve esophageal spasm due to its smooth muscle relaxant properties.","evidence":"Limited"},{"condition":"Biliary colic","description":"May be used off-label to relax biliary smooth muscle and relieve pain.","evidence":"Limited"}]
Primary treatment for: Acute angina pectoris
Also treats: Acute heart failure, Hypertensive emergencies, Controlled hypotension during surgery
📋 Drug Information
| Generic Name(s) | Nitroglycerin (25mg) |
| Brand Name | ng-care 25mg powder for injection |
| Manufacturer | Sympar Life Sciences |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | CARDIAC |
| Action Class | NO Donors |
| Route of Administration | Parenteral (intravenous or intra-arterial infusion) |
| Storage | Store at 20°C to 25°C (68°F to 77°F). Protect from light. Do not freeze. Keep in original container until use. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
Nitroglycerin is converted in the body to nitric oxide (NO), which activates guanylate cyclase. This leads to increased cyclic guanosine monophosphate (cGMP) levels, causing smooth muscle relaxation. The primary effect is vasodilation, which reduces preload and afterload, decreasing myocardial oxygen demand. It also dilates coronary arteries, improving blood flow to ischemic areas.
Mechanism Steps
💡 How to Take ng-care 25mg powder for injection
Strength: Injection: 25 mg in 5 mL (5 mg/mL) or as specified by the manufacturer.
Dosage Information
| Adult Dosage | The dose of this medicine is individualized by a qualified clinician based on the indication, patient's condition, and response. For acute angina or heart failure, a typical starting infusion rate is 5 to 10 mcg/min, titrated up to 200 mcg/min as needed. For controlled hypotension during surgery, the dose is adjusted to achieve the desired blood pressure. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients may be more sensitive to the hypotensive effects of nitroglycerin. Start with lower doses and titrate carefully. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. |
| Renal Impairment | No specific dose adjustment is recommended for renal impairment, but caution is advised. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. |
| Hepatic Impairment | Use with caution in patients with severe hepatic impairment. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. |
| Maximum Daily Dose | The maximum dose is not fixed and depends on the clinical response and indication. Doses up to 200 mcg/min have been used. Dose must be individualized by a qualified clinician. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of ng-care 25mg powder for injection
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Sildenafil | Major | |
| Tadalafil | Major | |
| Riociguat | Major | |
| Beta-blockers | Moderate | |
| Calcium channel blockers | Moderate | |
| Alcohol | Moderate | |
| Heparin | Minor | |
| Ergot alkaloids | Minor |
🚨 Major Interactions
- Phosphodiesterase-5 inhibitors (sildenafil, tadalafil, vardenafil)
- Riociguat
- Other nitrates or nitrites
⚡ Moderate Interactions
- Beta-blockers
- Calcium channel blockers
- Alcohol
🍷 Alcohol Interaction
Alcohol may potentiate the hypotensive effect of nitroglycerin, leading to severe dizziness, fainting, or cardiovascular collapse. Avoid alcohol consumption during treatment.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Hypersensitivity to nitroglycerin or other nitrates","Severe hypotension (systolic BP
⚠️ Warnings & Precautions
["Administer only in a setting with continuous monitoring.","Tolerance may develop with prolonged use; use lowest effective dose.","Avoid abrupt discontinuation to prevent rebound angina.","Use with caution in patients with glaucoma or increased intraocular pressure.","May cause methemoglobinemia; monitor if high doses or prolonged infusion.","Use with caution in patients with severe hepatic or renal impairment.","May impair ability to drive or operate machinery."]
🤱 Lactation Safety
It is not known whether nitroglycerin is excreted in human milk. Because many drugs are excreted in human milk, caution should be exercised when administered to a nursing woman.
💊 Overdose Management
Overdose can cause severe hypotension, tachycardia, bradycardia, and methemoglobinemia. Treatment includes discontinuation of the infusion, elevation of the legs, and administration of intravenous fluids. If methemoglobinemia is present, methylene blue may be used. Supportive care and monitoring are essential.
⏰ Missed Dose
This medicine is administered by healthcare professionals in a controlled setting. Missed doses are not applicable for patients self-administering. If a scheduled dose is missed in a hospital setting, the healthcare provider will determine the appropriate action based on the patient's condition.
Additional Safety Advice
This medicine must be administered only by a qualified healthcare professional in a setting equipped for continuous monitoring of blood pressure, heart rate, and other vital signs. The dose is titrated carefully to avoid severe hypotension. Patients should remain lying down during administration to prevent orthostatic hypotension. Do not use this medicine if you have taken sildenafil, tadalafil, or vardenafil within the last 24 to 48 hours, as this can cause a life-threatening drop in blood pressure. Inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding. This medicine may impair your ability to drive or operate machinery; avoid these activities until you know how it affects you. Do not stop the infusion suddenly without medical supervision, as this can cause rebound angina or hypertension. Always check the expiration date and inspect the solution for particles or discoloration before use.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients are more sensitive to the hypotensive effects of this medicine. Lower doses and careful titration are recommended. Monitor for dizziness and falls.
🤰 Pregnancy Planning (TTC)
If you are planning pregnancy, consult your doctor. This medicine should be used during pregnancy only if clearly needed. Discuss risks and benefits.
🏥 Post-Surgery Considerations
This medicine may be used during surgery for controlled hypotension. After surgery, your doctor will determine if continued use is necessary. Monitor for rebound hypertension if stopped.
🦷 Dental Procedures
Inform your dentist if you are on this medicine. It may interact with certain medications used in dental procedures, and you may need monitoring.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Avoid strenuous exercise while on this medicine, as it may worsen hypotension. Consult your doctor before starting any exercise program.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine is given in a hospital setting, so it does not directly impact daily work life. However, after treatment, you may need to avoid driving or operating machinery until your doctor says it is safe.
🛑 When to Stop This Medicine
This medicine is stopped by your healthcare provider based on your clinical response. Do not stop it abruptly on your own, as this can cause rebound angina or hypertension. Consult your doctor before stopping.
📅 Long-Term Use Effects
Long-term use of this medicine is not typical as it is used acutely. Prolonged continuous infusion can lead to tolerance, requiring higher doses. Rebound hypertension may occur if stopped abruptly. Monitoring for methemoglobinemia is advised with prolonged use.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
For long-term management of angina, oral nitrates like isosorbide mononitrate may be used.
Evidence: Well-establishedUsed for chronic angina and heart failure to reduce heart rate and oxygen demand.
Evidence: Well-establishedAlternative for angina if beta-blockers are not tolerated.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
No specific vaccine interactions are known. However, consult your doctor before receiving any vaccine while on this medicine.
📦 Storage Guide
✅ DO
Store at 20°C to 25°C (68°F to 77°F)
❌ DON'T
Do not freeze
✅ DO
Protect from light
❌ DON'T
Do not use if solution is discolored
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✈️ Traveling with This Medicine
This medicine is administered in a hospital setting and is not for self-administration during travel. If you are prescribed this medicine, ensure you have a copy of your prescription and medical records. Store it as directed by your healthcare provider. When traveling, carry it in its original packaging with the prescription label. Check with your airline about carrying injectable medications. For international travel, verify customs regulations regarding injectable drugs.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: This medicine starts working within 1 to 2 minutes after intravenous administration.
A: No, combining this medicine with sildenafil is contraindicated due to the risk of severe hypotension.
A: Common side effects include headache, dizziness, flushing, and low blood pressure.
A: It should be used during pregnancy only if clearly needed. Consult your doctor.
A: Store at 20°C to 25°C, protect from light, and do not freeze.
🤔 Common Patient Concerns
🔄 Substitutes for ng-care 25mg powder for injection
View AllAlternative brands with exact same active ingredient:
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nitrovir 25mg injectionChandra Bhagat Pharma Pvt Ltd ₹24.38 54.9% CHEAPER
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nitroplus 25mg injectionNeon Laboratories Ltd ₹32.44 39.9% CHEAPER
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nitrocin 25mg injectionSamarth Life Sciences Pvt Ltd ₹36.81 31.8% CHEAPER
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nig 25mg injectionVhb Life Sciences Inc ₹37.50 30.6% CHEAPER
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glynit 25mg injectionGeo Pharma Pvt Ltd ₹50.00 7.4% CHEAPER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: Nitroglycerin injection can be self-administered at home.
Fact: This medicine must be given by a healthcare professional in a monitored setting. - Myth: Nitroglycerin injection is safe to use with sildenafil.
Fact: Combining nitroglycerin with sildenafil can cause life-threatening hypotension and is contraindicated. - Myth: Nitroglycerin injection is addictive.
Fact: Nitroglycerin is not addictive, but tolerance can develop with continuous use.
🔄 Alternative Options
Generic Alternatives
- Nitroglycerin injection
Brand Alternatives
- Nitrostat
- Nitroject