nfd retard 10mg tablet sr - Nifedipine (10mg) medicine

Angiblock 10mg Capsule: Complete Medicine Guide

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🏭 Johnlee Pharmaceuticals Pvt Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Oct 30, 2026
🤰 Pregnancy Category Nifedipine is classified as Pregnancy Category C by the FDA. It should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus. It is sometimes used off-label for preterm labor, but only under close medical supervision. 📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Well-established for hypertension and angina.
Reviewed by
SaathiMed Expert Panel | Oct 30, 2026
🩺
Medically Fact-Checked & Clinically Verified by SaathiMed Clinical Review Board
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026

When to Call Your Doctor IMMEDIATELY

  • Severe chest pain or worsening angina
  • Fainting or severe dizziness
  • Swelling of face, lips, tongue, or throat
  • Irregular or very fast heartbeat
  • Yellowing of skin or eyes
  • Severe abdominal pain or vomiting blood
  • Decreased urine output

If experiencing severe symptoms, call emergency services immediately.

What is nfd retard 10mg tablet sr used for?

This medicine contains Nifedipine 10mg, a calcium channel blocker used to treat high blood pressure and angina. It works by relaxing blood vessels, making it easier for the heart to pump blood.

  • Generic Name: Nifedipine (10mg)
  • Manufacturer: Johnlee Pharmaceuticals Pvt Ltd
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 nfd retard 10mg tablet sr के बारे में (Hindi Summary)

उपयोग: यह दवा निफेडिपिन 10mg कैप्सूल है, जिसका उपयोग उच्च रक्तचाप (हाइपरटेंशन) और एंजाइना (सीने में दर्द) के इलाज के लिए किया जाता है। यह रक्त वाहिकाओं को आराम देकर चौड़ा करती है, जिससे रक्त प्रवाह आसान हो जाता है और हृदय पर दबाव कम होता है। यह दवा डॉक्टर के पर्चे के बिना नहीं लेनी चाहिए।

साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में सिरदर्द, चेहरे पर गर्मी लगना, चक्कर आना, और टखनों या पैरों में सूजन शामिल हैं। कुछ लोगों को मतली, अपच या कब्ज हो सकती है। दिल की धड़कन तेज हो सकती है। गंभीर दुष्प्रभाव दुर्लभ हैं, लेकिन यदि आपको गंभीर कम रक्तचाप, सीने में दर्द बढ़ना, या एलर्जी की प्रतिक्रिया हो तो तुरंत डॉक्टर से संपर्क करें।

सुरक्षा सलाह: इस दवा को डॉक्टर के निर्देशानुसार ही लें। कैप्सूल को चबाएं या तोड़ें नहीं, पूरा निगल लें। इसे भोजन के साथ या बिना भोजन के ले सकते हैं, लेकिन एक समय पर लें। अंगूर का जूस न पिएं क्योंकि इससे दवा का स्तर बढ़ सकता है। डॉक्टर की सलाह के बिना दवा बंद न करें। यदि आप गर्भवती हैं या स्तनपान करा रही हैं तो डॉक्टर को बताएं। चक्कर आ सकते हैं, इसलिए वाहन चलाने या मशीन चलाने से बचें।

💡 Did You Know? Over 80% of the antiretroviral drugs used globally to combat AIDS are supplied by Indian pharmaceutical companies.

💊 nfd retard 10mg tablet sr Uses & Benefits

[{"condition":"Hypertension","description":"This medicine helps lower high blood pressure by relaxing blood vessels, reducing the risk of strokes and heart attacks.","evidence":"Well-established"},{"condition":"Angina pectoris","description":"It relieves chest pain by improving blood flow to the heart muscle and reducing the heart's workload.","evidence":"Well-established"},{"condition":"Raynaud's phenomenon","description":"Sometimes used to reduce the frequency and severity of attacks in Raynaud's phenomenon, a condition where fingers and toes feel numb and cold.","evidence":"Limited"},{"condition":"Preterm labor","description":"Used off-label to relax uterine muscles and delay premature labor, but only under close medical supervision.","evidence":"Limited"}]

Off-label uses: [{"condition":"Anal fissure","description":"Topical nifedipine is sometimes used to relieve pain and promote healing of anal fissures.","evidence":"Limited"},{"condition":"High-altitude pulmonary edema","description":"Nifedipine may be used to prevent or treat high-altitude pulmonary edema in susceptible individuals.","evidence":"Limited"}]

Primary treatment for: Hypertension

Also treats: Angina pectoris, Raynaud's phenomenon

📋 Drug Information

Generic Name(s)Nifedipine (10mg)
Brand Namenfd retard 10mg tablet sr
ManufacturerJohnlee Pharmaceuticals Pvt Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassCARDIAC
Action ClassCalcium channel blockers- Dihydropyridines (DHP)
Route of AdministrationOral
StorageStore at room temperature (15-30°C) in a dry place, away from direct sunlight and moisture. Keep in the original container.
Shelf Life24 months from the date of manufacture.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Take this medicine at the same time each day to maintain consistent blood levels.
2
Monitor your blood pressure regularly and keep a record to share with your doctor.
3
Avoid grapefruit juice and alcohol while taking this medicine.
4
Do not stop this medicine suddenly without consulting your doctor, as it can worsen your condition.
5
Report any swelling of ankles, feet, or sudden weight gain to your doctor.
6
If you experience dizziness, rise slowly from sitting or lying positions.
7
Inform your doctor about all other medicines you are taking, including over-the-counter drugs.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅
High blood pressure
This medicine is commonly prescribed for this.
Likely Use
✅
Chest pain (angina)
This medicine helps relieve angina.
Likely Use
❌
Fever
This medicine is not a fever reducer.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionThis medicine is rapidly and almost completely absorbed from the gastrointestinal tract after oral administration. However, it undergoes extensive first-pass metabolism in the liver, which reduces its systemic bioavailability.
DistributionNifedipine is highly bound to plasma proteins and distributes widely into body tissues. It crosses the placenta and is excreted in breast milk.
Protein BindingApproximately 92-98% bound to plasma proteins.
MetabolismThis medicine is extensively metabolized in the liver by the cytochrome P450 enzyme system, primarily CYP3A4. The metabolites are inactive.
Half-LifeThe elimination half-life is approximately 2 to 5 hours for immediate-release formulations.
ExcretionMetabolites are excreted mainly in the urine, with a small amount in the feces.
BioavailabilityThe oral bioavailability of immediate-release nifedipine is approximately 45-70% due to first-pass metabolism.
Onset of ActionThe onset of action for immediate-release nifedipine is within 20 to 30 minutes after oral administration.
Peak Plasma TimePeak plasma concentrations are reached within 30 to 60 minutes for immediate-release capsules.
Duration of ActionThe duration of action is approximately 4 to 8 hours for immediate-release formulations.

How It Works

This medicine works by blocking calcium channels in the smooth muscle cells of blood vessels. Calcium is needed for these muscles to contract. By blocking calcium entry, the medicine causes the muscles to relax, which widens the blood vessels (vasodilation). This lowers blood pressure and improves blood flow to the heart, reducing the frequency and severity of angina attacks.

Mechanism Steps

1
Calcium channel blockade: This medicine binds to L-type calcium channels on the surface of smooth muscle cells in blood vessels.
2
Reduced calcium influx: By blocking these channels, it prevents calcium from entering the cells, which is necessary for muscle contraction.
3
Smooth muscle relaxation: With less calcium, the smooth muscle cells relax, causing the blood vessels to widen.
4
Vasodilation and reduced blood pressure: The widening of blood vessels lowers peripheral resistance, which reduces blood pressure and improves blood flow to the heart.

💡 How to Take nfd retard 10mg tablet sr

Strength: Nifedipine 10mg immediate-release capsule

1Swallow the capsule whole with a glass of water.
2Do not crush, chew, or break the capsule.
3Take with or without food, but be consistent.
4Avoid grapefruit juice.
5Take at the same times each day.

Dosage Information

Adult DosageThe usual adult dose of this medicine is 10mg taken three times a day for immediate-release capsules. However, the dose may be adjusted by your doctor based on your condition and response. The maximum daily dose is typically 30mg to 60mg, but should not exceed 90mg per day. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageElderly patients may be more sensitive to the effects of this medicine, especially dizziness and hypotension. Start with a lower dose and monitor closely.
Renal ImpairmentNo specific dose adjustment is required for renal impairment, but use with caution and monitor blood pressure.
Hepatic ImpairmentUse with caution in patients with hepatic impairment. Dose reduction may be necessary. Monitor liver function.
Maximum Daily Dose90mg per day

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With food
Take with meals
Reduces stomach upset.
Grapefruit
Avoid
May increase drug levels.

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of nfd retard 10mg tablet sr

✅ Common Side Effects

Headache (Common (5-10%))
Usually resolves on its own. Consult doctor if persistent or severe.
Flushing (Common (5-10%))
This is a temporary effect. Stay hydrated and avoid alcohol.
Dizziness (Common (5-10%))
Rise slowly from sitting or lying position. Avoid driving if affected.
Peripheral edema (swelling of ankles/feet) (Common (5-10%))
Elevate legs when resting. Consult doctor if severe or persistent.
Nausea (Uncommon (1-5%))
Take with food to reduce nausea. Consult doctor if it continues.

🚨 Serious Side Effects

Severe hypotension (Rare (<0.1%))
Seek immediate medical attention if you feel faint, have blurred vision, or a very slow heartbeat.
Worsening angina or heart attack (Rare (<0.1%))
Get emergency help if chest pain worsens or you have symptoms of a heart attack.
Allergic reactions (Rare (<0.1%))
Seek immediate medical help if you experience rash, itching, swelling of face/lips/tongue, or difficulty breathing.
Hepatotoxicity (Very rare (<0.01%))
Report yellowing of skin or eyes, dark urine, or severe abdominal pain to your doctor immediately.

⚠️ Rare Side Effects

Gingival hyperplasia
Maintain good oral hygiene and consult a dentist if gums become swollen or bleed.
Photosensitivity
Use sunscreen and protective clothing when outdoors.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Ketoconazole Major
Rifampin Major
Beta-blockers Major
Grapefruit juice Major
Digoxin Moderate
Quinidine Moderate
Cimetidine Moderate
Tacrolimus Moderate
Antacids Minor
NSAIDs Minor

🚨 Major Interactions

  • CYP3A4 inhibitors (e.g., ketoconazole, itraconazole, clarithromycin)
  • CYP3A4 inducers (e.g., rifampin, carbamazepine, phenytoin)
  • Beta-blockers
  • Grapefruit juice

⚡ Moderate Interactions

  • Digoxin
  • Quinidine
  • Cimetidine
  • Tacrolimus

🍷 Alcohol Interaction

Alcohol may enhance the blood pressure-lowering effect of this medicine, leading to dizziness, fainting, or increased heart rate. It is advisable to avoid or limit alcohol consumption while taking this medicine.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Hypersensitivity to nifedipine or other dihydropyridine calcium channel blockers","Cardiogenic shock","Severe aortic stenosis","Unstable angina (immediate-release form)","Within 4 weeks of a myocardial infarction","Concurrent use with rifampin"]

⚠️ Warnings & Precautions

["May cause severe hypotension and dizziness; avoid driving or operating machinery until you know how it affects you.","Do not stop taking this medicine abruptly, as it can cause rebound angina or hypertension.","Use with caution in patients with heart failure or compromised cardiac function.","Grapefruit juice can increase drug levels; avoid it.","May cause peripheral edema; report persistent swelling to your doctor.","Use with caution in elderly patients and those with liver or kidney impairment."]

🤱 Lactation Safety

Nifedipine is excreted in breast milk in small amounts. It is generally considered safe during breastfeeding, but consult your doctor before use.

💊 Overdose Management

Overdose can cause severe hypotension, tachycardia, and loss of consciousness. Seek immediate medical attention. Treatment is supportive and may include intravenous fluids, vasopressors, and calcium gluconate.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up.

Additional Safety Advice

General Safety

Take this medicine exactly as prescribed by your doctor. Do not crush, chew, or break the capsule; swallow it whole with a glass of water. It can be taken with or without food, but taking it with food may reduce stomach upset. Avoid drinking grapefruit juice while taking this medicine, as it can increase the amount of medicine in your blood and cause side effects. Do not stop taking this medicine suddenly without consulting your doctor, as this can worsen your condition. Inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding. Also tell your doctor about all other medicines you are taking, especially blood pressure medicines, antibiotics, and antifungal drugs. Avoid driving or operating heavy machinery until you know how this medicine affects you, as it can cause dizziness.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients may be more sensitive to the blood pressure-lowering effects. Start with a lower dose and monitor closely for dizziness and falls.

🤰 Pregnancy Planning (TTC)

If you are planning to become pregnant, consult your doctor. This medicine should be used during pregnancy only if clearly needed. Your doctor may switch to a safer alternative.

🏥 Post-Surgery Considerations

Inform your surgeon and anesthesiologist that you are taking this medicine. It may interact with anesthesia and affect blood pressure during surgery.

🦷 Dental Procedures

Inform your dentist that you are taking this medicine, as it can cause gum swelling and may interact with certain dental anesthetics.

💚 Lifestyle Tips for Better Results

🏃
Maintain a healthy weight to reduce strain on your heart.
🥗
Engage in regular physical activity like walking or swimming, as advised by your doctor.
😴
Limit salt intake to help control blood pressure.
💧
Avoid smoking and limit alcohol consumption.
🧘
Manage stress through relaxation techniques like deep breathing or meditation.
🌞
Get adequate sleep.

🏋️ Exercise Considerations

Moderate exercise is generally safe, but avoid sudden strenuous activities that can cause a sudden drop in blood pressure. Stay hydrated and rise slowly after exercise.

🥗 Diet Recommendations

Include potassium-rich foods like bananas and oranges.
Reduce sodium intake.
Eat a balanced diet rich in fruits and vegetables.
Avoid grapefruit juice.
Limit caffeine and alcohol.

💼 Impact on Daily Work & Life

This medicine may cause dizziness, especially when you start taking it. Avoid driving or operating heavy machinery until you know how it affects you. Most people can continue their normal activities with caution.

🛑 When to Stop This Medicine

Do not stop this medicine without consulting your doctor. If you experience severe side effects, contact your doctor immediately. Your doctor may adjust the dose or switch to another medicine.

📅 Long-Term Use Effects

Long-term use of this medicine is generally safe when monitored by a doctor. Regular check-ups for blood pressure, heart rate, and signs of swelling are recommended. In rare cases, long-term use may cause gum swelling or liver problems. Do not stop the medicine without consulting your doctor.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Lifestyle modifications

Diet, exercise, and stress reduction can help manage hypertension and angina.

Evidence: Well-established
Other antihypertensive medicines

ACE inhibitors, ARBs, or beta-blockers may be alternatives.

Evidence: Well-established

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

No specific interactions with vaccines are known. However, consult your doctor before any vaccination.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

Carry this medicine in its original packaging with a copy of your prescription. Store it at room temperature and protect it from extreme heat or cold. If traveling across time zones, adjust your dosing schedule gradually under your doctor&#039;s guidance. Keep enough supply for the entire trip and carry it in your hand luggage.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 55-year-old man with high blood pressure
He was prescribed this medicine for hypertension. After taking it regularly for a month, his blood pressure stabilized. He experienced mild dizziness initially but it subsided. He learned to avoid grapefruit juice and to take the medicine at the same time daily.
💡 Lesson: Consistency and avoiding grapefruit juice are key to managing side effects and achieving good blood pressure control.
👤 A 62-year-old woman with angina
She had frequent chest pain on exertion. Her doctor prescribed this medicine. Within two weeks, her angina attacks reduced significantly. She was advised to monitor her blood pressure and report any swelling in her legs.
💡 Lesson: This medicine can effectively reduce angina attacks, but regular monitoring and reporting of side effects are important.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: This medicine starts working within 20-30 minutes after taking a dose, but it may take a few days to see the full effect on blood pressure.

Q: Can I take this medicine with food?

A: Yes, you can take it with or without food, but taking it with food may reduce stomach upset. Avoid grapefruit juice.

Q: What should I do if I miss a dose?

A: If you miss a dose, take it as soon as you remember. If it's almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my kidney function?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?

🔄 Substitutes for nfd retard 10mg tablet sr

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: This medicine can be stopped once blood pressure is normal.
    Fact: High blood pressure often has no symptoms, and stopping this medicine can cause a dangerous rise in blood pressure. Always consult your doctor before stopping.
  • Myth: This medicine can be taken with grapefruit juice.
    Fact: Grapefruit juice can increase the levels of this medicine in your blood, leading to side effects. Avoid it.

🔄 Alternative Options

Generic Alternatives

  • Nifedipine 10mg capsule

Brand Alternatives

  • Angiblock 10mg capsule

📊 Comparison with Similar Medicines

[{"medicine":"Nifedipine","class":"Calcium channel blocker","half_life":"2-5 hours","onset":"20-30 minutes","common_uses":"Hypertension, angina"},{"medicine":"Amlodipine","class":"Calcium channel blocker","half_life":"30-50 hours","onset":"6-12 hours","common_uses":"Hypertension, angina"}]

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