Neftum Axt 250mg Tablet: Complete Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Blood in stool or vomit
- Severe abdominal pain
- Chest pain or difficulty breathing
- Severe headache with visual changes
- Sudden swelling of face, lips, or throat
- Yellowing of skin or eyes
- Decreased urine output
- Unusual bruising or bleeding
If experiencing severe symptoms, call emergency services immediately.
What is neftum axt 250mg tablet used for?
This medicine is a combination of aceclofenac and paracetamol used for short-term relief of acute pain and inflammation. It works by reducing prostaglandins that cause pain and swelling. Take it with food, avoid alcohol, and do not exceed the prescribed dose.
- Generic Name: Information coming soon
- Manufacturer: Multiple manufacturers
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 neftum axt 250mg tablet के बारे में (Hindi Summary)
उपयोग: यह दवा एसिफेनाक और पैरासिटामोल का संयोजन है, जिसका उपयोग तीव्र दर्द और सूजन के इलाज के लिए किया जाता है। यह जोड़ों के दर्द, मांसपेशियों के दर्द, दांत के दर्द, मासिक धर्म के दर्द और सर्जरी के बाद के दर्द में राहत देती है। यह दवा शरीर में प्रोस्टाग्लैंडिन नामक रसायन को कम करके दर्द और सूजन को कम करती है। इसे डॉक्टर के निर्देशानुसार ही लें।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में मतली, उल्टी, पेट दर्द, अपच, सिरदर्द, चक्कर आना और नींद आना शामिल हैं। गंभीर दुष्प्रभावों में पेट या आंतों में रक्तस्राव, अल्सर, एलर्जी प्रतिक्रिया, लिवर या किडनी की समस्या हो सकती है। यदि आपको काला मल, खून की उल्टी, त्वचा पर चकत्ते, सूजन या सांस लेने में कठिनाई हो तो तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: इस दवा को हमेशा डॉक्टर के निर्देशानुसार ही लें। खाली पेट न लें, भोजन के साथ लें। शराब का सेवन न करें। यदि आपको पेट अल्सर, गुर्दे या लिवर की गंभीर बीमारी है तो इस दवा का सेवन न करें। गर्भावस्था या स्तनपान के दौरान डॉक्टर से सलाह लें। दवा लेते समय वाहन चलाने या मशीनरी चलाने से बचें यदि आपको चक्कर या नींद आती है। दवा को बच्चों की पहुंच से दूर रखें।
💊 neftum axt 250mg tablet Uses & Benefits
[{"condition":"Osteoarthritis","description":"Provides symptomatic relief of pain and inflammation in joints affected by osteoarthritis.","evidence":"Well-established"},{"condition":"Rheumatoid arthritis","description":"Helps reduce joint pain and swelling in rheumatoid arthritis as an adjunct to disease-modifying therapy.","evidence":"Well-established"},{"condition":"Acute musculoskeletal pain","description":"Used for short-term relief of pain from muscle strains, sprains, and soft tissue injuries.","evidence":"Well-established"},{"condition":"Dental pain","description":"Effective for relief of post-dental procedure pain and toothache.","evidence":"Well-established"},{"condition":"Post-operative pain","description":"Used for short-term management of mild to moderate post-surgical pain.","evidence":"Well-established"},{"condition":"Dysmenorrhea","description":"Relieves menstrual cramps and associated pain.","evidence":"Moderate"}]
Off-label uses: [{"condition":"Migraine","description":"Sometimes used for acute migraine attacks, but not a first-line treatment.","evidence":"Limited"},{"condition":"Ankylosing spondylitis","description":"May be used for pain relief in ankylosing spondylitis, though evidence is limited.","evidence":"Limited"}]
Primary treatment for: Acute musculoskeletal pain
Also treats: Osteoarthritis, Rheumatoid arthritis, Dental pain, Post-operative pain, Dysmenorrhea
📋 Drug Information
| Generic Name(s) | Information coming soon |
| Brand Name | neftum axt 250mg tablet |
| Manufacturer | Multiple manufacturers |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | ANTI INFECTIVES |
| Action Class | Cephalosporins: 2nd generation |
| Route of Administration | Oral |
| Storage | Store at room temperature (15-30°C) in a cool, dry place. Protect from light and moisture. Keep out of reach of children. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine combines two active ingredients with complementary mechanisms. Aceclofenac, an NSAID, inhibits the cyclooxygenase (COX) enzymes, particularly COX-2, leading to decreased synthesis of prostaglandins, prostacyclin, and thromboxane from arachidonic acid. This results in reduced inflammation, pain, and fever. Paracetamol acts primarily in the central nervous system by inhibiting prostaglandin synthesis and possibly activating descending serotonergic pathways, producing analgesia and antipyresis. The combination provides enhanced pain relief through both peripheral anti-inflammatory and central analgesic actions.
Mechanism Steps
💡 How to Take neftum axt 250mg tablet
Strength: Tablet containing aceclofenac 100 mg and paracetamol 325 mg.
Dosage Information
| Adult Dosage | The usual adult dose is one tablet taken orally two to three times daily, preferably after meals. The maximum daily dose should not exceed three tablets in 24 hours. The dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Do not exceed the recommended dose or duration without medical advice. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients may be more sensitive to the effects of this medicine. Use the lowest effective dose for the shortest duration. Monitor renal and hepatic function closely. Dose must be individualized by a qualified clinician. |
| Renal Impairment | Use with caution in patients with renal impairment. Dose reduction may be necessary. Avoid in severe renal impairment (eGFR <30 mL/min). Consult a doctor for individualized dosing. |
| Hepatic Impairment | Use with caution in patients with hepatic impairment. Dose reduction may be necessary. Avoid in severe hepatic impairment. Consult a doctor for individualized dosing. |
| Maximum Daily Dose | Maximum daily dose is 3 tablets in 24 hours. Do not exceed the recommended dose. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of neftum axt 250mg tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | |
| Other NSAIDs | Major | |
| Corticosteroids | Major | |
| Methotrexate | Major | |
| ACE inhibitors/ARBs | Moderate | |
| Diuretics | Moderate | |
| Lithium | Moderate | |
| SSRIs | Moderate | |
| Antacids | Minor | |
| Cholestyramine | Minor |
🚨 Major Interactions
- Warfarin
- Other NSAIDs (e.g., ibuprofen, naproxen)
- Corticosteroids
- Methotrexate
- ACE inhibitors and ARBs
⚡ Moderate Interactions
- Diuretics (e.g., furosemide, hydrochlorothiazide)
- Lithium
- SSRIs
- Antihypertensives (beta-blockers, calcium channel blockers)
🍷 Alcohol Interaction
Avoid alcohol consumption while taking this medicine. Alcohol increases the risk of gastrointestinal bleeding, ulceration, and liver toxicity, especially with paracetamol. It can also enhance drowsiness and dizziness.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Hypersensitivity to aceclofenac, paracetamol, or any component of the formulation","Active peptic ulcer or history of recurrent peptic ulcer","Gastrointestinal bleeding or perforation","Severe heart failure","Severe renal impairment (eGFR
⚠️ Warnings & Precautions
["Take with food to minimize gastrointestinal irritation.","Avoid alcohol consumption.","Use with caution in elderly patients due to increased risk of side effects.","Monitor renal and hepatic function during prolonged use.","May impair ability to drive or operate machinery.","Discontinue if signs of gastrointestinal bleeding occur.","Not recommended for patients with aspirin-sensitive asthma.","Use with caution in patients with hypertension or cardiovascular disease."]
🤱 Lactation Safety
Aceclofenac and paracetamol are excreted in breast milk in small amounts. Consult your doctor before use during breastfeeding. Short-term use may be considered if benefits outweigh risks.
💊 Overdose Management
Overdose may cause nausea, vomiting, abdominal pain, drowsiness, and in severe cases, liver and kidney damage. Seek immediate medical attention. Treatment is supportive and symptomatic. For paracetamol overdose, N-acetylcysteine is the antidote and should be administered as soon as possible. Activated charcoal may be considered if presented within 1-2 hours of ingestion.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for a missed one.
Additional Safety Advice
Always take this medicine exactly as prescribed by your doctor. Do not exceed the recommended dose or duration of treatment. Take the tablet with food or milk to reduce the risk of stomach upset. Avoid alcohol consumption while taking this medicine, as it can increase the risk of gastrointestinal bleeding and liver damage. Do not use this medicine if you have a history of peptic ulcer, severe kidney or liver disease, or if you are allergic to any of its ingredients. Inform your doctor about all other medications you are taking, especially blood thinners, antihypertensives, and other pain relievers. Do not drive or operate heavy machinery if you experience dizziness or drowsiness. If you are pregnant, planning to become pregnant, or breastfeeding, consult your doctor before using this medicine. Keep this medicine out of the reach of children. Store it in a cool, dry place away from direct sunlight.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients are at higher risk of gastrointestinal bleeding, kidney impairment, and cardiovascular events. Use the lowest effective dose for the shortest duration and monitor renal and hepatic function closely.
🤰 Pregnancy Planning (TTC)
Consult your doctor before taking this medicine if you are planning to become pregnant. NSAIDs may affect ovulation and are generally avoided during pregnancy, especially in the third trimester.
🏥 Post-Surgery Considerations
This medicine may be used for post-operative pain relief. However, it may increase the risk of bleeding. Inform your surgeon if you are taking this medicine before any surgery.
🦷 Dental Procedures
Inform your dentist if you are taking this medicine before any dental procedure, as it may increase the risk of bleeding.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Avoid strenuous exercise or activities that may increase pain while taking this medicine. Consult your doctor before starting any exercise program.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause dizziness or drowsiness, which can affect your ability to drive or operate machinery. Avoid these activities until you know how the medicine affects you. It may also cause stomach upset, so take it with food.
🛑 When to Stop This Medicine
Stop taking this medicine and consult your doctor if you experience severe side effects such as gastrointestinal bleeding, allergic reactions, or if your pain does not improve within a few days. Do not stop abruptly if you have been on long-term therapy without medical advice.
📅 Long-Term Use Effects
Long-term use of this medicine may increase the risk of gastrointestinal bleeding, kidney impairment, liver toxicity, and cardiovascular events. Regular monitoring of kidney and liver function is recommended. Use the lowest effective dose for the shortest duration.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Can complement medicine for chronic pain and improve mobility.
Evidence: Well-establishedApplying heat or cold packs can help reduce pain and inflammation.
Evidence: ModerateMay provide pain relief for some individuals.
Evidence: Limited💉 Vaccination Considerations
💉 If You're Getting Vaccinated
No specific interactions with vaccines are established. However, if you are scheduled for vaccination, inform your healthcare provider about all medicines you are taking.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
Carry this medicine in its original packaging with a copy of your prescription. Store at room temperature and protect from light and moisture. If traveling across time zones, adjust dosing schedule as advised by your doctor. Check customs regulations for carrying prescription medicines.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: Pain relief typically begins within 30 to 60 minutes after taking the tablet.
A: It is best to take this medicine with food or milk to reduce stomach upset.
A: Do not take other NSAIDs or paracetamol-containing products without consulting your doctor, as it may increase the risk of side effects.
A: This medicine is usually prescribed for short-term use. Do not take it for longer than prescribed without medical advice.
🤔 Common Patient Concerns
🛑 Myths vs. Facts
- Myth: This medicine can be taken for any type of pain.
Fact: It is specifically for inflammatory and acute pain; it is not a first-line treatment for all pain types. - Myth: It is safe to take this medicine for long periods without monitoring.
Fact: Long-term use requires medical supervision and monitoring of kidney, liver, and gastrointestinal health. - Myth: Taking this medicine with alcohol is safe.
Fact: Alcohol increases the risk of gastrointestinal bleeding and liver damage.
🔄 Alternative Options
Generic Alternatives
- Aceclofenac 100 mg + Paracetamol 325 mg tablet
Brand Alternatives
- Neftum AXT 250mg Tablet