Nicorandil 10mg Tablet: Complete Guide To Uses, Side Effects, And Safety
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Severe chest pain that does not respond to rest or nitroglycerin
- Fainting or severe dizziness
- Sudden swelling of face, lips, or throat
- Difficulty breathing
- Blood in stool or vomit
- Unusual sores or ulcers in mouth, skin, or genitals
- Yellowing of skin or eyes
If experiencing severe symptoms, call emergency services immediately.
What is ncrd 10mg tablet used for?
This medicine is a potassium channel opener used to prevent angina attacks. It works by relaxing blood vessels to improve blood flow to the heart. It is taken orally, usually twice daily, and is not for immediate relief of acute angina.
- Generic Name: Information coming soon
- Manufacturer: Multiple manufacturers
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 ncrd 10mg tablet के बारे में (Hindi Summary)
उपयोग: यह दवा एंजाइना (सीने में दर्द) को रोकने और इलाज के लिए इस्तेमाल की जाती है। यह रक्त वाहिकाओं को फैलाकर दिल तक रक्त का प्रवाह बढ़ाती है और दिल पर दबाव कम करती है। यह दवा तीव्र एंजाइना के दौरे के तत्काल राहत के लिए नहीं है, बल्कि दीर्घकालिक प्रबंधन के लिए है।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में सिरदर्द, चक्कर आना, फ्लशिंग और मतली शामिल हैं। ये आमतौर पर हल्के होते हैं और अपने आप ठीक हो जाते हैं। गंभीर दुष्प्रभाव दुर्लभ हैं, लेकिन अगर आपको गंभीर निम्न रक्तचाप, अल्सर, या एलर्जी की प्रतिक्रिया हो तो तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: इस दवा को लेने से पहले अपने डॉक्टर को अपनी सभी स्वास्थ्य समस्याओं और दवाओं के बारे में बताएं। गर्भावस्था या स्तनपान के दौरान डॉक्टर की सलाह के बिना न लें। शराब से बचें क्योंकि इससे रक्तचाप कम हो सकता है। जब तक आपको पता न चले कि यह दवा आपको कैसे प्रभावित करती है, वाहन न चलाएं। दवा को अचानक बंद न करें।
💊 ncrd 10mg tablet Uses & Benefits
- [{"condition":"Chronic stable angina","description":"This medicine is used for the long-term prevention of angina attacks in patients with coronary artery disease.
- It helps reduce the frequency and severity of chest pain episodes.","evidence":"Well-established"},{"condition":"Unstable angina","description":"In some cases, this medicine may be used as part of a treatment regimen for unstable angina, under close medical supervision.","evidence":"Moderate"},{"condition":"Post-myocardial infarction angina","description":"This medicine can be prescribed after a heart attack to reduce the risk of recurrent angina and improve outcomes.","evidence":"Moderate"}]
Off-label uses: [{"condition":"Prevention of contrast-induced nephropathy","description":"Some studies suggest nicorandil may help protect kidney function in patients undergoing procedures with contrast dye, but this is not a standard use.","evidence":"Limited"},{"condition":"Raynaud's phenomenon","description":"Rarely, nicorandil has been used to improve blood flow in patients with Raynaud's phenomenon, but evidence is limited.","evidence":"Limited"}]
Primary treatment for: Angina pectoris
Also treats: Coronary artery disease, Post-myocardial infarction
📋 Drug Information
| Generic Name(s) | Information coming soon |
| Brand Name | ncrd 10mg tablet |
| Manufacturer | Multiple manufacturers |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | CARDIAC |
| Action Class | Potassium channel opener |
| Route of Administration | Oral |
| Storage | Store at room temperature (15-30°C) in a dry place, away from direct sunlight and moisture. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine works by opening potassium channels in the smooth muscle cells of blood vessels, leading to hyperpolarization and relaxation of the vascular smooth muscle. This results in vasodilation, particularly of the coronary arteries and veins. Additionally, it has a nitrate-like effect that increases cyclic guanosine monophosphate (cGMP) levels, further promoting vasodilation. By dilating coronary arteries, it improves blood supply to the heart muscle, and by dilating peripheral veins, it reduces preload and cardiac workload. This dual mechanism helps relieve and prevent angina.
Mechanism Steps
💡 How to Take ncrd 10mg tablet
Strength: 10 mg tablet
Dosage Information
| Adult Dosage | The usual adult dose of this medicine is 10 mg to 20 mg taken twice daily. The dose may be adjusted by your doctor based on your condition and response to treatment. The maximum recommended daily dose is 40 mg. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients may be more sensitive to the effects of this medicine, especially hypotension and dizziness. Start with a lower dose and monitor closely. |
| Renal Impairment | No specific dose adjustment is recommended for mild to moderate renal impairment. Use with caution in severe renal impairment. |
| Hepatic Impairment | No specific dose adjustment is recommended for mild to moderate hepatic impairment. Use with caution in severe hepatic impairment. |
| Maximum Daily Dose | 40 mg |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of ncrd 10mg tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Sildenafil | Major | |
| Nitroglycerin | Major | |
| Metoprolol | Moderate | |
| Amlodipine | Moderate | |
| Alcohol | Moderate |
🚨 Major Interactions
- Phosphodiesterase-5 inhibitors (e.g., sildenafil, tadalafil)
- Nitrates (e.g., nitroglycerin, isosorbide mononitrate)
⚡ Moderate Interactions
- Beta-blockers
- Calcium channel blockers
- Alcohol
🍷 Alcohol Interaction
Alcohol may enhance the blood pressure-lowering effect of this medicine, leading to dizziness, lightheadedness, and increased risk of fainting. It is advisable to avoid alcohol while taking this medicine.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Allergy to nicorandil or any component of the tablet","Cardiogenic shock","Left ventricular failure with low filling pressure","Severe hypotension","Concomitant use with phosphodiesterase-5 inhibitors","Concomitant use with nitrates"]
⚠️ Warnings & Precautions
["May cause severe hypotension, especially in patients with low blood pressure or dehydration.","Rarely causes ulcerations in the mouth, intestines, skin, and genitals. Stop treatment and consult a doctor if ulcers occur.","Use with caution in patients with heart failure, recent myocardial infarction, or valvular heart disease.","Avoid abrupt withdrawal as it may worsen angina.","May impair ability to drive or operate machinery due to dizziness."]
🤱 Lactation Safety
It is not known whether this medicine passes into breast milk. Consult your doctor before breastfeeding.
💊 Overdose Management
Overdose may cause severe hypotension, tachycardia, and fainting. Seek immediate medical attention. Treatment is supportive and symptomatic. There is no specific antidote.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose.
Additional Safety Advice
Before taking this medicine, inform your doctor if you have low blood pressure, heart failure, or any liver or kidney problems. Do not take this medicine if you are pregnant or planning to become pregnant without consulting your doctor. It is not known if this medicine passes into breast milk, so breastfeeding mothers should consult their doctor. Avoid alcohol while taking this medicine as it can increase the risk of low blood pressure and dizziness. Do not drive or operate heavy machinery until you know how this medicine affects you. Do not stop taking this medicine abruptly without your doctor's advice, as this can worsen your angina. Always take this medicine exactly as prescribed. If you miss a dose, take it as soon as you remember, but if it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose. Keep this medicine out of reach of children. Store at room temperature away from moisture and heat.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients are more prone to hypotension and dizziness. Start with a lower dose and monitor blood pressure regularly.
🤰 Pregnancy Planning (TTC)
Consult your doctor if you are planning pregnancy. This medicine should be used during pregnancy only if clearly needed.
🏥 Post-Surgery Considerations
Inform your surgeon and anesthesiologist that you are taking this medicine, as it may affect blood pressure during surgery.
🦷 Dental Procedures
Inform your dentist that you are taking this medicine, as it may cause low blood pressure during procedures. Your dentist may need to take precautions.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Avoid strenuous exercise until you know how this medicine affects you, as it may cause dizziness or low blood pressure. Consult your doctor before starting any exercise program.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause dizziness or low blood pressure, which can affect your ability to drive or operate machinery. Avoid these activities until you know how it affects you. It should not significantly impact desk work.
🛑 When to Stop This Medicine
Do not stop this medicine without consulting your doctor. If you experience serious side effects like ulcers or severe hypotension, stop and seek medical advice immediately.
📅 Long-Term Use Effects
Long-term use of this medicine is generally safe and effective for angina prevention. Regular monitoring of blood pressure and symptoms is recommended. Rarely, long-term use may be associated with ulcerations. Periodic review with your doctor is advised.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Diet, exercise, and stress reduction can complement medicine for angina.
Evidence: Well-establishedBeta-blockers, calcium channel blockers, or nitrates may be alternatives.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
No specific vaccine interactions are known. However, consult your doctor before receiving any vaccine while on this medicine.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
When traveling, carry this medicine in its original packaging with a copy of your prescription. Store it at room temperature and protect it from moisture. If crossing time zones, adjust your dosing schedule gradually in consultation with your doctor. Keep enough supply for your trip and carry it in your hand luggage.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: This medicine starts working within 30 minutes to 1 hour, but its full benefits in preventing angina may take a few weeks.
A: Yes, but inform your doctor as dose adjustments may be needed.
A: Headaches are common initially and usually subside. If they persist or are severe, consult your doctor.
🤔 Common Patient Concerns
🛑 Myths vs. Facts
- Myth: This medicine can be taken for immediate chest pain relief.
Fact: This medicine is for prevention of angina, not for immediate relief of an acute attack. Use fast-acting nitrates for acute attacks. - Myth: This medicine can be stopped abruptly without any risk.
Fact: Abrupt withdrawal can worsen angina. Always consult your doctor before stopping.
🔄 Alternative Options
Generic Alternatives
- Nicorandil 10 mg tablet
Brand Alternatives
- Nicorandil 10 mg tablet (various brands)