nano tears 0.1% eye drop - Ciclosporin (0.1% w/v) medicine

Hydroeyes HS Eye Drop: Comprehensive Guide to Uses, Side Effects, and Safety

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🏭 Sunways India Pvt Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Sep 24, 2026
📋 Prescription Required 💊 Generic Available
Medically Reviewed
12 min read
Evidence: Well-established for chronic dry eye disease.
Reviewed by
SaathiMed Expert Panel | Sep 24, 2026

When to Call Your Doctor IMMEDIATELY

  • Severe eye pain or sudden vision loss
  • Swelling of the face, lips, or throat
  • Signs of eye infection such as purulent discharge, increased redness, or sensitivity to light
  • Persistent blurred vision or visual disturbances
  • Severe allergic reaction with rash, itching, or difficulty breathing
  • Eye injury or trauma while using this medicine

If experiencing severe symptoms, call emergency services immediately.

What is nano tears 0.1% eye drop used for?

This medicine is a prescription eye drop containing ciclosporin 0.1% w/v. It is used to treat chronic dry eye disease by reducing inflammation on the eye's surface. It is typically used twice daily and may take several weeks to show full effect.

  • Generic Name: Ciclosporin (0.1% w/v)
  • Manufacturer: Sunways India Pvt Ltd
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 nano tears 0.1% eye drop के बारे में (Hindi Summary)

उपयोग: यह दवा सूखी आँखों (ड्राई आई) के इलाज के लिए आँखों में डालने वाली दवा है। इसमें साइक्लोस्पोरिन 0.1% होता है, जो आँखों की सतह पर सूजन को कम करता है। यह उन मरीजों के लिए है जिन्हें साधारण आँखों की बूँदों से आराम नहीं मिलता। यह दवा आँसू बनाने वाली ग्रंथियों की कार्यक्षमता को सुधारती है और आँखों की जलन, खुजली और सूखेपन को कम करती है। इसे डॉक्टर की सलाह पर ही इस्तेमाल करें।

साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में आँख में जलन, लालिमा, धुंधली दृष्टि और आँख में कुछ महसूस होना शामिल है। ये आमतौर पर हल्के होते हैं और कुछ समय में ठीक हो जाते हैं। गंभीर दुष्प्रभाव दुर्लभ हैं, लेकिन यदि आँख में तेज दर्द, सूजन, या दृष्टि में अचानक कमी हो तो तुरंत डॉक्टर से मिलें।

सुरक्षा सलाह: इस दवा का उपयोग करने से पहले और बाद में अपने हाथ धोएँ। ड्रॉपर की नोक को आँख या किसी सतह से न छुएँ। यदि आप कॉन्टैक्ट लेंस पहनते हैं, तो दवा डालने से पहले उन्हें निकाल लें और 15 मिनट बाद ही वापस पहनें। अन्य आँखों की दवाओं के साथ उपयोग करते समय 5-10 मिनट का अंतराल रखें। दवा को ठंडी और सूखी जगह पर रखें। डॉक्टर की सलाह के बिना दवा बंद न करें।

💡 Did You Know? India has the highest number of USFDA-compliant plants outside the USA.

💊 nano tears 0.1% eye drop Uses & Benefits

  • [{"condition":"Chronic dry eye disease","description":"This medicine is indicated to increase tear production in patients with keratoconjunctivitis sicca who have not responded to topical lubricants.
  • It reduces ocular surface inflammation and improves symptoms of dryness, burning, and foreign body sensation.","evidence":"Well-established"},{"condition":"Ocular surface inflammation associated with autoimmune diseases","description":"It may be used to manage dry eye associated with Sjögren's syndrome or other autoimmune conditions, where inflammation plays a key role.","evidence":"Moderate"}]

Off-label uses: [{"condition":"Vernal keratoconjunctivitis","description":"Sometimes prescribed off-label to reduce severe allergic inflammation of the conjunctiva and cornea.","evidence":"Limited"},{"condition":"Atopic keratoconjunctivitis","description":"May be used off-label for chronic allergic eye disease unresponsive to conventional therapy.","evidence":"Limited"}]

Primary treatment for: Chronic dry eye disease (keratoconjunctivitis sicca)

Also treats: Sjögren's syndrome-associated dry eye, Ocular surface inflammation

📋 Drug Information

Generic Name(s)Ciclosporin (0.1% w/v)
Brand Namenano tears 0.1% eye drop
ManufacturerSunways India Pvt Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassOPHTHAL
Action ClassImmunosuppressant- Calcineurin inhibitors
Route of AdministrationOphthalmic
StorageStore at room temperature between 15°C and 25°C. Do not freeze. Keep the bottle tightly closed when not in use. Protect from light.
Shelf LifeRefer to the expiry date printed on the packaging. Discard the bottle 4 weeks after opening, or as directed by the manufacturer.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Instruct patients to shake the bottle well before each use to ensure the emulsion is properly mixed.
2
Advise patients to remove contact lenses before application and wait at least 15 minutes before reinserting them.
3
Remind patients that this medicine is for long-term use and may take several weeks to show full effect; encourage adherence.
4
Warn patients not to touch the dropper tip to any surface to prevent contamination and infection.
5
Educate patients about the signs of ocular infection and instruct them to seek immediate care if they occur.
6
Recommend waiting at least 5 minutes between this medicine and other eye drops to avoid washout.
7
Schedule regular follow-up visits to monitor treatment response and ocular surface health.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅
Chronic eye dryness
This medicine is commonly prescribed for this.
Likely Use
✅
Eye redness
May be used if redness is due to inflammation.
Likely Use
❌
Acute eye infection
This medicine is contraindicated in active eye infections.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionSystemic absorption of ciclosporin following topical ocular administration of this medicine is minimal. Studies have shown that blood concentrations of ciclosporin remain below the limit of quantification in most patients after using the 0.1% emulsion. Therefore, systemic pharmacokinetics are not clinically relevant for this route.
DistributionNot established from the available information.
Protein BindingNot established from the available information.
MetabolismNot established from the available information.
Half-LifeNot established from the available information.
ExcretionNot established from the available information.
BioavailabilityNot established from the available information.
Onset of ActionThe onset of therapeutic effect of this medicine is gradual. Some patients may notice improvement in symptoms within 2 to 4 weeks, but the full benefits typically require 3 to 6 months of consistent use.
Peak Plasma TimeNot established from the available information.
Duration of ActionThe effects of this medicine are sustained with regular twice-daily dosing. The duration of action is related to the continuous suppression of T-cell activation, which persists as long as the medicine is used.

How It Works

This medicine contains ciclosporin, a cyclic polypeptide immunosuppressant. When applied topically to the eye, ciclosporin binds to cyclophilin, a cytosolic protein, forming a complex that inhibits calcineurin. Calcineurin is a phosphatase required for the activation of the transcription factor nuclear factor of activated T-cells (NFAT). By inhibiting calcineurin, this medicine prevents the dephosphorylation and nuclear translocation of NFAT, thereby blocking the transcription of genes encoding pro-inflammatory cytokines such as interleukin-2. This leads to a selective suppression of T-cell activation and proliferation in the ocular surface, reducing inflammation and allowing for improved tear production.

Mechanism Steps

1
Penetration into T-cells: Ciclosporin, the active ingredient in this medicine, diffuses into T-lymphocytes present in the ocular surface tissues.
2
Binding to cyclophilin: Inside the cell, ciclosporin binds with high affinity to cyclophilin, forming a drug-protein complex.
3
Inhibition of calcineurin: The ciclosporin-cyclophilin complex binds to and inhibits calcineurin, a calcium-dependent phosphatase.
4
Blockade of NFAT dephosphorylation: Inhibition of calcineurin prevents the dephosphorylation of nuclear factor of activated T-cells (NFAT), a critical transcription factor.
5
Reduced cytokine production: Without dephosphorylated NFAT, the transcription of genes for interleukin-2 and other pro-inflammatory cytokines is suppressed.
6
Decreased T-cell activation: The lack of cytokine signaling leads to reduced activation, proliferation, and recruitment of T-cells in the eye.
7
Resolution of inflammation: The overall effect is a decrease in ocular surface inflammation, which helps restore normal tear production and reduce symptoms of dry eye.

💡 How to Take nano tears 0.1% eye drop

Strength: Ciclosporin 0.1% w/v ophthalmic emulsion

1Wash your hands thoroughly with soap and water.
2Shake the bottle gently to mix the emulsion.
3Tilt your head back and pull down your lower eyelid to form a small pocket.
4Hold the dropper above your eye and squeeze one drop into the pocket.
5Close your eye gently and press the inner corner of your eye with your finger for 1-2 minutes to help the medicine stay in the eye.
6Repeat for the other eye if prescribed.
7Replace the cap tightly and wash your hands again.

Dosage Information

Adult DosageThe usual adult dose of this medicine is one drop instilled into each affected eye twice daily, approximately 12 hours apart. The dose must be individualized by a qualified clinician based on the severity of the condition and response to therapy. Do not exceed the prescribed frequency. If you are using other eye drops, wait at least 5 to 10 minutes between applications. Follow your ophthalmologist's instructions carefully.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatric ophthalmologist.
Elderly DosageNo specific dose adjustment is required for elderly patients. However, elderly patients should be monitored for any signs of ocular infection or worsening of symptoms.
Renal ImpairmentNo dose adjustment is required for renal impairment due to minimal systemic absorption.
Hepatic ImpairmentNo dose adjustment is required for hepatic impairment due to minimal systemic absorption.
Maximum Daily DoseThe maximum recommended daily dose is one drop in each affected eye twice daily. Do not exceed this unless directed by your doctor.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

⏰ What to Do If You Miss a Dose

📌 Less than 6 hours since missed dose
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than 6 hours since missed dose
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of nano tears 0.1% eye drop

✅ Common Side Effects

Burning or stinging upon instillation (Common (10-20%))
This usually resolves within a few minutes. If it persists or becomes severe, consult your eye doctor.
Eye redness (Common (5-10%))
Redness often decreases with continued use. If it worsens or is accompanied by pain, seek medical advice.
Blurred vision (Common (5-10%))
Wait until vision clears before driving or operating machinery. If blurred vision persists, contact your doctor.
Foreign body sensation (Common (5-10%))
This is usually temporary. If it continues, discuss with your ophthalmologist.

🚨 Serious Side Effects

Severe allergic reaction (anaphylaxis) (Rare (<0.1%))
Seek emergency medical help immediately if you experience swelling of the face, lips, throat, or difficulty breathing.
Ocular infection (e.g., bacterial, viral, fungal) (Rare (<0.1%))
Contact your eye doctor promptly if you develop eye pain, discharge, or worsening redness.
Corneal damage (Rare (<0.1%))
Report any persistent eye pain, vision changes, or sensitivity to light to your ophthalmologist.

⚠️ Rare Side Effects

Eyelid swelling
Consult your doctor if swelling occurs.
Eye discharge
Seek medical advice if discharge is purulent or persistent.

Consult your doctor if you experience any unusual symptoms.

🛡️ Safety & Warnings

🚫 Contraindications

["Known hypersensitivity to ciclosporin or any component of this medicine.","Active ocular or periocular infection.","History of ocular herpes simplex virus infection."]

⚠️ Warnings & Precautions

["This medicine is for topical ophthalmic use only and must not be injected or ingested.","Remove contact lenses before use and wait at least 15 minutes before reinserting.","Do not touch the dropper tip to any surface to avoid contamination.","If you develop an eye infection, consult your doctor; continued use may worsen the infection.","The safety and efficacy of this medicine in children under 16 years have not been established.","Use with caution in patients with a history of ocular surgery or trauma.","Inform your doctor if you are pregnant, planning pregnancy, or breastfeeding."]

🤱 Lactation Safety

It is not known whether ciclosporin from this medicine is excreted in human breast milk. Since systemic absorption is negligible, the risk to a breastfed infant is likely low. However, consult your doctor before using this medicine while breastfeeding.

💊 Overdose Management

Overdose with this medicine is unlikely due to its topical route. If accidental ingestion occurs, seek medical attention. In case of excessive topical application, rinse the eye with water and consult a doctor if irritation persists.

⏰ Missed Dose

If you miss a dose of this medicine, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up.

Additional Safety Advice

General Safety

Wash your hands thoroughly before and after applying this medicine. Do not touch the tip of the dropper to your eye, eyelid, or any surface to avoid contamination. Remove soft contact lenses before instilling the drops and wait at least 15 minutes before reinserting them, as the preservative in the formulation may be absorbed by the lenses. If you are using other eye drops, wait at least 5 to 10 minutes between applications to prevent dilution. Do not use this medicine if the emulsion appears discolored or contains particles. Keep the bottle tightly closed when not in use and store it as directed. Do not share this medicine with others. Inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding. Do not drive or operate heavy machinery immediately after instilling the drops if your vision is temporarily blurred. Avoid rubbing your eyes after application.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients may be more prone to ocular infections due to age-related immune changes. Regular monitoring is advised. No dose adjustment is required.

🤰 Pregnancy Planning (TTC)

If you are planning to become pregnant, consult your doctor before using this medicine. The safety of this medicine during pregnancy has not been established, but systemic absorption is minimal.

🏥 Post-Surgery Considerations

This medicine may be prescribed after certain eye surgeries to reduce inflammation. Follow your surgeon's instructions carefully regarding its use.

🦷 Dental Procedures

No specific precautions are needed for dental procedures while using this medicine, as it has minimal systemic absorption.

💚 Lifestyle Tips for Better Results

🏃
Use a humidifier at home or work to add moisture to the air.
🥗
Avoid sitting in direct drafts from air conditioners or fans.
😴
Take frequent breaks from screens and blink consciously.
💧
Wear wraparound sunglasses outdoors to protect your eyes from wind and sun.
🧘
Stay well hydrated by drinking plenty of water.
🌞
Avoid smoking and exposure to secondhand smoke.

🏋️ Exercise Considerations

No specific exercise restrictions are required while using this medicine. However, if you experience blurred vision after application, avoid activities that require clear vision until it resolves.

🥗 Diet Recommendations

Include omega-3 fatty acids from fish or flaxseed to support eye health.
Eat a balanced diet rich in vitamins A, C, and E.
Stay hydrated by drinking adequate water throughout the day.
Limit caffeine and alcohol as they can contribute to dryness.

💼 Impact on Daily Work & Life

This medicine may cause temporary blurred vision immediately after instillation. If this occurs, wait until your vision clears before driving or operating machinery. Otherwise, it should not significantly impact your daily activities. You can continue your normal work routine.

🛑 When to Stop This Medicine

Do not stop using this medicine without consulting your ophthalmologist. If you experience serious side effects or if your doctor decides to discontinue treatment, follow their instructions. Abrupt cessation may lead to recurrence of symptoms.

📅 Long-Term Use Effects

Long-term use of this medicine is generally well-tolerated. However, because it suppresses local immune responses, there is a potential for increased risk of ocular infections. Regular follow-up with your ophthalmologist is recommended to monitor for any adverse effects. The medicine is intended for chronic use, and your doctor will determine the duration of therapy based on your condition.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Artificial tears

Lubricating eye drops that provide temporary relief but do not treat underlying inflammation.

Evidence: Well-established
Punctal plugs

Small devices inserted into tear ducts to reduce tear drainage, helping keep the eye moist.

Evidence: Well-established
Lifitegrast ophthalmic solution

Another prescription eye drop for dry eye with a different mechanism of action.

Evidence: Well-established

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

No specific interactions between this medicine and vaccines are expected due to minimal systemic absorption. However, consult your doctor before receiving any vaccine while using this medicine.

📦 Storage Guide

✅ DO

Store at room temperature (15-25°C)

❌ DON'T

Do not freeze

✅ DO

Keep the bottle tightly closed when not in use

❌ DON'T

Do not leave the cap off

✅ DO

Protect from light

❌ DON'T

Do not store in direct sunlight

✅ DO

Discard 4 weeks after opening

❌ DON'T

Do not use beyond the expiry date

✈️ Traveling with This Medicine

When traveling with this medicine, keep it in its original packaging with the prescription label. Carry a copy of your prescription in case of customs checks. Store it at room temperature and protect it from extreme heat or cold. If traveling by air, keep it in your carry-on luggage to avoid temperature fluctuations in checked baggage. Continue your regular dosing schedule; if crossing time zones, consult your doctor for adjustments if needed.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 52-year-old woman with chronic dry eye due to Sjögren's syndrome
She had tried numerous artificial tears with little relief. Her ophthalmologist prescribed this medicine twice daily. After 6 weeks, she noticed a significant decrease in burning and foreign body sensation. She continues to use it regularly and reports improved quality of life.
💡 Lesson: Consistent use of this medicine can provide substantial relief for chronic dry eye, but patience is key as it takes time to work.
👤 A 45-year-old man with dry eye after LASIK surgery
He experienced persistent dryness and blurred vision post-surgery. His doctor recommended this medicine. He initially felt stinging upon instillation but this subsided after a few days. Over 3 months, his symptoms improved markedly, and he was able to reduce the use of artificial tears.
💡 Lesson: Temporary stinging is common but usually resolves; long-term use can improve ocular surface health after surgery.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: This medicine may take several weeks to months to show its full effect. Some patients notice improvement in 2-4 weeks, but maximum benefit often requires 3-6 months of consistent use.

Q: Can I use this medicine with contact lenses?

A: You should remove your contact lenses before applying this medicine and wait at least 15 minutes before reinserting them, as the preservative may be absorbed by the lenses.

Q: What should I do if I miss a dose?

A: If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose.

Q: Is this medicine safe during pregnancy?

A: The safety of this medicine during pregnancy has not been established. Consult your doctor before use if you are pregnant or planning to become pregnant.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I use this medicine long-term?
  • Will it affect my vision?
  • Can I drive after using this medicine?
  • Does it interact with other eye drops?
  • What if I miss a dose?
  • Can I wear contact lenses while using this medicine?

🔄 Substitutes for nano tears 0.1% eye drop

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: This medicine works immediately like artificial tears.
    Fact: This medicine is not a lubricant; it treats inflammation and may take weeks to months for full effect.
  • Myth: This medicine can be used for any type of eye redness.
    Fact: It is specifically for chronic dry eye associated with inflammation and should only be used under a doctor's supervision.

📊 Comparison with Similar Medicines

[{"medicine":"This medicine (Ciclosporin 0.1%)","class":"Calcineurin inhibitor","route":"Ophthalmic","primary_use":"Chronic dry eye","frequency":"Twice daily"},{"medicine":"Ciclosporin 0.05%","class":"Calcineurin inhibitor","route":"Ophthalmic","primary_use":"Chronic dry eye","frequency":"Twice daily"},{"medicine":"Lifitegrast 5%","class":"LFA-1 antagonist","route":"Ophthalmic","primary_use":"Chronic dry eye","frequency":"Twice daily"}]

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