metwon am 5mg/25mg tablet - Amlodipine (5mg) + Metoprolol Succinate (25mg) medicine

Amlosat M 5mg/25mg Tablet: Complete Medicine Guide

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🏭 Walron Healthcare Pvt Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Sep 23, 2026
📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Well-established for hypertension and angina.
Reviewed by
SaathiMed Expert Panel | Sep 23, 2026

When to Call Your Doctor IMMEDIATELY

  • Severe dizziness or fainting
  • Difficulty breathing or wheezing
  • Chest pain that worsens
  • Swelling of face, lips, or throat
  • Heart rate below 50 beats per minute
  • Yellowing of skin or eyes
  • Unusual bleeding or bruising

If experiencing severe symptoms, call emergency services immediately.

What is metwon am 5mg/25mg tablet used for?

This medicine is a combination of amlodipine and metoprolol used to treat high blood pressure and angina. It works by relaxing blood vessels and slowing the heart rate.

  • Generic Name: Amlodipine (5mg) + Metoprolol Succinate (25mg)
  • Manufacturer: Walron Healthcare Pvt Ltd
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 metwon am 5mg/25mg tablet के बारे में (Hindi Summary)

उपयोग: यह दवा उच्च रक्तचाप (हाइपरटेंशन) और एंजाइना (सीने में दर्द) के इलाज के लिए इस्तेमाल की जाती है। यह रक्त वाहिकाओं को आराम देकर और हृदय की गति को धीमा करके रक्तचाप को कम करती है। यह उन रोगियों के लिए निर्धारित की जाती है जिनका रक्तचाप एक दवा से नियंत्रित नहीं होता। इसे डॉक्टर के निर्देशानुसार ही लें।

साइड इफेक्ट्स: आम दुष्प्रभावों में चक्कर आना, थकान, सिरदर्द, पैरों में सूजन और हृदय गति का धीमा होना शामिल हैं। गंभीर दुष्प्रभाव दुर्लभ हैं लेकिन यदि सांस लेने में कठिनाई, बेहोशी या गंभीर एलर्जी हो तो तुरंत डॉक्टर से संपर्क करें।

सुरक्षा सलाह: इस दवा को डॉक्टर के निर्देशानुसार ही लें। अचानक बंद न करें, इससे एंजाइना या दिल का दौरा पड़ सकता है। शराब से बचें। यदि आप गर्भवती हैं या स्तनपान करा रही हैं तो डॉक्टर से सलाह लें। नियमित रूप से रक्तचाप और हृदय गति की जांच कराएं।

💡 Did You Know? India has the highest number of USFDA-compliant plants outside the USA.

💊 metwon am 5mg/25mg tablet Uses & Benefits

[{"condition":"Hypertension","description":"Lowers blood pressure by reducing peripheral vascular resistance and cardiac output.","evidence":"Well-established"},{"condition":"Angina pectoris","description":"Reduces frequency and severity of angina attacks by decreasing myocardial oxygen demand.","evidence":"Well-established"},{"condition":"Heart rate control","description":"Metoprolol component helps control rapid heart rates in conditions like atrial fibrillation.","evidence":"Well-established"}]

Off-label uses: [{"condition":"Migraine prophylaxis","description":"Sometimes used off-label to prevent migraines, though not first-line.","evidence":"Limited"},{"condition":"Anxiety with palpitations","description":"Beta-blocker component may help reduce physical symptoms of anxiety.","evidence":"Limited"}]

Primary treatment for: Hypertension

Also treats: Angina pectoris, Atrial fibrillation, Heart failure (stable)

📋 Drug Information

Generic Name(s)Amlodipine (5mg) + Metoprolol Succinate (25mg)
Brand Namemetwon am 5mg/25mg tablet
ManufacturerWalron Healthcare Pvt Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassCARDIAC
Action Class
Route of AdministrationOral
StorageStore at room temperature (15-30°C) in a dry place, away from direct sunlight.
Shelf Life24 months from the date of manufacture.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Take this medicine at the same time each day, preferably in the morning.
2
Monitor your blood pressure and heart rate regularly.
3
Do not stop this medicine abruptly without consulting your doctor.
4
Avoid alcohol while taking this medicine.
5
Inform your doctor if you have asthma, diabetes, or liver disease.
6
Report any unusual symptoms like severe dizziness, fainting, or difficulty breathing.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

High blood pressure
This medicine is commonly prescribed for this.
Likely Use
Chest pain (angina)
This medicine helps prevent angina attacks.
Likely Use
Fever
This medicine is not a fever reducer.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionAmlodipine is well absorbed orally, with peak plasma concentrations reached in 6-12 hours. Metoprolol succinate is absorbed throughout the gastrointestinal tract, with peak levels at 3-7 hours. Food does not significantly affect absorption.
DistributionAmlodipine has a large volume of distribution (about 21 L/kg) and is highly protein-bound. Metoprolol has a volume of distribution of about 3.2 L/kg and crosses the blood-brain barrier.
Protein BindingAmlodipine is approximately 93% bound to plasma proteins. Metoprolol is about 12% bound.
MetabolismAmlodipine is extensively metabolized in the liver, primarily by CYP3A4. Metoprolol is metabolized in the liver by CYP2D6.
Half-LifeAmlodipine half-life is 30-50 hours. Metoprolol succinate half-life is 3-7 hours.
ExcretionAmlodipine is excreted in urine as metabolites. Metoprolol is excreted primarily in urine as metabolites.
BioavailabilityAmlodipine bioavailability is about 64-90%. Metoprolol succinate bioavailability is about 50%.
Onset of ActionAmlodipine onset is 30-50 minutes; Metoprolol succinate onset is within 1-2 hours.
Peak Plasma TimeAmlodipine peak at 6-12 hours; Metoprolol succinate peak at 3-7 hours.
Duration of ActionAmlodipine duration is 24 hours; Metoprolol succinate duration is about 24 hours.

How It Works

This medicine combines two antihypertensive agents with complementary mechanisms. Amlodipine inhibits the influx of calcium ions into vascular smooth muscle and cardiac muscle, causing vasodilation and reduced peripheral resistance. Metoprolol succinate selectively blocks beta-1 adrenergic receptors in the heart, reducing heart rate, contractility, and cardiac output. Together, they lower blood pressure and decrease myocardial oxygen demand.

Mechanism Steps

1
Calcium channel blockade: Amlodipine blocks L-type calcium channels in vascular smooth muscle, preventing calcium influx and causing relaxation of blood vessels.
2
Vasodilation: Relaxation of peripheral arterioles reduces systemic vascular resistance, lowering blood pressure.
3
Beta-1 receptor blockade: Metoprolol selectively blocks beta-1 receptors in the heart, reducing heart rate and contractility.
4
Reduced cardiac output: Decreased heart rate and contractility lower cardiac output, further reducing blood pressure.
5
Decreased myocardial oxygen demand: The combined effects reduce the heart's oxygen consumption, alleviating angina.

💡 How to Take metwon am 5mg/25mg tablet

Strength: Tablet containing Amlodipine 5 mg and Metoprolol Succinate 25 mg.

1Take the tablet whole with a glass of water.
2Swallow it whole; do not crush or chew.
3Take it at the same time each day.
4Can be taken with or without food.
5Do not stop suddenly without consulting your doctor.

Dosage Information

Adult DosageThe usual adult dose is one tablet once daily, preferably in the morning. Dose may be adjusted by your doctor based on blood pressure response and tolerability. Do not exceed the prescribed dose. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageElderly patients may be more sensitive to the effects of this medicine. Start with a lower dose and monitor closely. Dose must be individualized by a qualified clinician.
Renal ImpairmentNo specific dose adjustment is typically required for mild to moderate renal impairment. In severe renal impairment, use with caution and monitor. Dose must be individualized by a qualified clinician.
Hepatic ImpairmentIn hepatic impairment, amlodipine clearance is reduced. Start with a lower dose and titrate slowly. Dose must be individualized by a qualified clinician.
Maximum Daily DoseThe maximum recommended daily dose is one tablet of 5 mg/25 mg. Do not exceed without medical advice.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With or without food
Can be taken with or without food
Food does not significantly affect absorption.
Grapefruit
Avoid
May increase amlodipine levels.

⏰ What to Do If You Miss a Dose

📌 Less than 12 hours late
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than 12 hours late
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of metwon am 5mg/25mg tablet

✅ Common Side Effects

Dizziness (Common (5-10%))
Rise slowly from sitting or lying position. Consult doctor if persistent.
Fatigue (Common (5-10%))
Ensure adequate rest. Consult doctor if severe.
Headache (Common (5-10%))
Usually resolves. Consult doctor if severe or persistent.
Peripheral edema (Common (5-10%))
Elevate legs. Consult doctor if worsening.
Bradycardia (Common (5-10%))
Monitor heart rate. Consult doctor if below 50 bpm.

🚨 Serious Side Effects

Severe hypotension (Rare (<0.1%))
Seek immediate medical attention if you feel faint or have very low blood pressure.
Worsening heart failure (Rare (<0.1%))
Report increased shortness of breath, swelling, or fatigue immediately.
Bronchospasm (Rare (<0.1%))
Seek medical help if you experience difficulty breathing or wheezing.
Severe allergic reaction (Rare (<0.1%))
Call emergency services if you have swelling of face, lips, or throat.

⚠️ Rare Side Effects

Jaundice
Report yellowing of skin or eyes to doctor immediately.
Agranulocytosis
Report unexplained fever, sore throat, or infections.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
CYP3A4 inhibitors Major
CYP2D6 inhibitors Major
Verapamil Major
NSAIDs Moderate
Alpha-blockers Moderate
Antacids Minor

🚨 Major Interactions

  • CYP3A4 inhibitors (e.g., ketoconazole, clarithromycin)
  • CYP2D6 inhibitors (e.g., paroxetine, fluoxetine)
  • Verapamil or diltiazem

⚡ Moderate Interactions

  • NSAIDs
  • Alpha-blockers

🍷 Alcohol Interaction

Alcohol may enhance the blood pressure-lowering and dizziness effects of this medicine. Avoid or limit alcohol consumption.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Severe bradycardia","Second or third-degree heart block","Cardiogenic shock","Severe asthma or COPD","Known hypersensitivity to amlodipine or metoprolol"]

⚠️ Warnings & Precautions

["Do not stop abruptly; taper gradually.","May mask symptoms of hypoglycemia in diabetics.","Use caution in patients with peripheral vascular disease.","May worsen psoriasis.","Avoid in patients with pheochromocytoma unless alpha-blockade is established."]

🤱 Lactation Safety

Amlodipine and metoprolol are excreted in breast milk. Caution is advised. Consult your doctor before breastfeeding.

💊 Overdose Management

Overdose may cause severe hypotension, bradycardia, heart failure, and bronchospasm. Seek emergency medical attention. Treatment is supportive and symptomatic, including atropine for bradycardia, vasopressors for hypotension, and glucagon if needed.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose.

Additional Safety Advice

General Safety

Take this medicine exactly as prescribed. Do not stop suddenly, as abrupt withdrawal of Metoprolol can worsen angina or cause a heart attack. Avoid alcohol as it may increase dizziness and low blood pressure. Inform your doctor if you have asthma, diabetes, or liver disease. Regular monitoring of blood pressure and heart rate is important. Do not use potassium supplements without medical advice. If you become pregnant or plan to breastfeed, consult your doctor before continuing this medicine.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients may be more sensitive to blood pressure lowering and heart rate slowing. Start with a lower dose and monitor closely.

🤰 Pregnancy Planning (TTC)

Consult your doctor before planning pregnancy. This medicine may not be suitable during pregnancy; alternative treatments may be recommended.

🏥 Post-Surgery Considerations

Inform your surgeon and anesthesiologist about this medicine. It may need to be temporarily stopped before surgery as advised.

🦷 Dental Procedures

Inform your dentist about this medicine. It may affect blood pressure and heart rate during dental procedures.

💚 Lifestyle Tips for Better Results

🏃
Maintain a healthy weight.
🥗
Follow a low-salt diet.
😴
Exercise regularly as advised by your doctor.
💧
Avoid smoking and limit alcohol.
🧘
Manage stress through relaxation techniques.
🌞
Get adequate sleep.

🏋️ Exercise Considerations

Avoid strenuous exercise initially as it may cause dizziness. Consult your doctor before starting any new exercise regimen.

🥗 Diet Recommendations

Reduce salt intake.
Eat plenty of fruits and vegetables.
Limit processed foods.
Stay well hydrated.

💼 Impact on Daily Work & Life

May cause dizziness or fatigue, especially when starting treatment. Avoid driving or operating heavy machinery until you know how this medicine affects you.

🛑 When to Stop This Medicine

Do not stop this medicine without consulting your doctor. Abrupt withdrawal can cause serious heart problems. Your doctor will decide if and when to stop.

📅 Long-Term Use Effects

Long-term use requires regular monitoring of blood pressure, heart rate, and renal function. It is generally safe for long-term use when prescribed and monitored. Do not stop without medical advice.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Lifestyle modifications

Diet, exercise, and stress reduction can complement medication.

Evidence: Well-established
Other antihypertensive classes

ACE inhibitors, ARBs, or diuretics may be alternatives.

Evidence: Well-established

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

No specific vaccine interactions are known. Continue routine vaccinations as advised by your doctor.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

Carry this medicine in its original packaging with a copy of your prescription. Store at room temperature and protect from moisture. If traveling across time zones, consult your doctor about adjusting the dosing schedule. Keep enough supply for the entire trip.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 55-year-old man with hypertension and angina
He was prescribed this medicine after his blood pressure remained high on amlodipine alone. Within a few weeks, his blood pressure stabilized and angina episodes reduced. He experienced mild dizziness initially, which subsided. He was advised not to stop the medicine suddenly.
💡 Lesson: Combination therapy can be more effective for some patients, but adherence and monitoring are key.
👤 A 62-year-old woman with hypertension and rapid heart rate
She started this medicine and noticed improvement in palpitations and blood pressure. She was cautioned about abrupt withdrawal and advised regular follow-up. She maintained a low-salt diet and walked daily.
💡 Lesson: Lifestyle modifications along with medication improve outcomes.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: This medicine starts lowering blood pressure within a few hours, but full effects may take 1-2 weeks.

Q: Can I stop taking this medicine if I feel better?

A: No, do not stop without consulting your doctor. Stopping suddenly can worsen your condition.

Q: What should I do if I miss a dose?

A: Take it as soon as you remember. If it's almost time for the next dose, skip the missed dose and continue your regular schedule.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my kidney function?
  • Can I drive after taking this medicine?
  • Does it interact with my other blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?

🔄 Substitutes for metwon am 5mg/25mg tablet

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: This medicine can be stopped once blood pressure is normal.
    Fact: High blood pressure often requires long-term treatment. Stopping suddenly can be dangerous.
  • Myth: This medicine causes kidney damage.
    Fact: It is used to protect kidneys in many patients with high blood pressure. Regular monitoring is advised.

🔄 Alternative Options

Generic Alternatives

  • Amlodipine + Metoprolol Succinate generic tablets

Brand Alternatives

  • Amlosat M 5mg/25mg Tablet

📊 Comparison with Similar Medicines

[{"medicine":"Amlodipine + Metoprolol Succinate","key_difference":"Combines calcium channel blocker and beta-blocker for dual mechanism."},{"medicine":"Amlodipine alone","key_difference":"Only calcium channel blocker; no heart rate control."},{"medicine":"Metoprolol alone","key_difference":"Only beta-blocker; less effective for vasodilation."}]

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