medabzol 400mg oral drops - Albendazole (400mg/5ml) medicine

Medabzol 400mg Oral Drops: Complete Medicine Guide

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🏭 Medbionic Healthcare 📦 Varies by brand 💊 Allopathy 📅 Updated: Sep 25, 2026
⚠️ Hepatotoxicity Risk 🤰 Pregnancy Category Albendazole is not recommended during pregnancy, especially in the first trimester, unless the potential benefit justifies the potential risk. It has been associated with teratogenic effects in animal studies. Women of childbearing age should use effective contraception during treatment. 📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: High for intestinal worms; moderate for tissue infections.
Reviewed by
SaathiMed Expert Panel | Sep 25, 2026
🩺
Medically Fact-Checked & Clinically Verified by SaathiMed Clinical Review Board
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026

When to Call Your Doctor IMMEDIATELY

  • Yellowing of skin or eyes (jaundice)
  • Severe abdominal pain
  • Persistent vomiting
  • Unusual bruising or bleeding
  • Signs of infection (fever, sore throat)
  • Swelling of face, lips, or throat
  • Difficulty breathing
  • Seizures
  • Blood in stool or vomit

If experiencing severe symptoms, call emergency services immediately.

What is medabzol 400mg oral drops used for?

This medicine contains albendazole, an anti-worm medicine used to treat infections caused by roundworms, hookworms, pinworms, and other parasites. It works by killing the worms, which are then expelled from the body.

  • Generic Name: Albendazole (400mg/5ml)
  • Manufacturer: Medbionic Healthcare
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 medabzol 400mg oral drops के बारे में (Hindi Summary)

उपयोग: यह दवा अल्बेंडाजोल नामक एंटी-हेल्मिंथिक दवा है, जिसका उपयोग विभिन्न प्रकार के कीड़ों के संक्रमण के इलाज के लिए किया जाता है। यह गोल कृमि, हुकवर्म, पिनवर्म, व्हिपवर्म और थ्रेडवर्म जैसे परजीवी कीड़ों को मारती है। यह कीड़ों को ग्लूकोज अवशोषित करने से रोकती है, जिससे वे मर जाते हैं। यह दवा 400 मिलीग्राम प्रति 5 मिलीलीटर की खुराक में उपलब्ध है और बच्चों और वयस्कों दोनों के लिए उपयुक्त है।

साइड इफेक्ट्स: आम दुष्प्रभावों में पेट दर्द, मतली, उल्टी, सिरदर्द और चक्कर आना शामिल हैं। ये आमतौर पर हल्के और अस्थायी होते हैं। गंभीर दुष्प्रभाव दुर्लभ हैं लेकिन इनमें लीवर की समस्या, अस्थि मज्जा का दमन और गंभीर एलर्जी प्रतिक्रियाएं शामिल हो सकती हैं। यदि आपको लगातार उल्टी, आंखों या त्वचा का पीलापन, असामान्य थकान या संक्रमण के लक्षण दिखाई दें तो तुरंत डॉक्टर से संपर्क करें।

सुरक्षा सलाह: इस दवा को अपने डॉक्टर के निर्देशानुसार ही लें। अधिक या कम मात्रा में न लें। इसे आमतौर पर भोजन के साथ लिया जाता है ताकि पेट की परेशानी कम हो। पूरा कोर्स पूरा करें, भले ही आप बेहतर महसूस करें। शौचालय का उपयोग करने के बाद और खाने से पहले अपने हाथ अच्छी तरह धोएं। यदि आप गर्भवती हैं या गर्भधारण की योजना बना रही हैं, तो इस दवा को लेने से पहले अपने डॉक्टर को बताएं।

💡 Did You Know? India has the highest number of USFDA-compliant plants outside the USA.

💊 medabzol 400mg oral drops Uses & Benefits

[{"condition":"Roundworm infection (Ascariasis)","description":"Effectively treats intestinal roundworm infections by killing the adult worms.","evidence":"Well-established"},{"condition":"Hookworm infection","description":"Eradicates hookworms from the intestine, relieving symptoms like anemia and abdominal pain.","evidence":"Well-established"},{"condition":"Pinworm infection (Enterobiasis)","description":"Treats pinworm infections, often requiring a second dose after two weeks.","evidence":"Well-established"},{"condition":"Whipworm infection (Trichuriasis)","description":"Effective against whipworm, reducing worm burden and symptoms.","evidence":"Well-established"},{"condition":"Threadworm infection (Strongyloidiasis)","description":"Used to treat threadworm infections, though alternative agents may be preferred.","evidence":"Moderate"},{"condition":"Hydatid disease (Echinococcosis)","description":"Used for tissue infections caused by Echinococcus tapeworm larvae, often as adjunct to surgery.","evidence":"Well-established"},{"condition":"Neurocysticercosis","description":"Treats brain infection caused by Taenia solium larvae, often with anti-inflammatory drugs.","evidence":"Well-established"}]

Off-label uses: [{"condition":"Cutaneous larva migrans","description":"Sometimes used off-label for skin infections caused by hookworm larvae.","evidence":"Limited"},{"condition":"Giardiasis","description":"Occasionally used off-label for Giardia infections, though other drugs are preferred.","evidence":"Limited"}]

Primary treatment for: Parasitic worm infections

Also treats: Hydatid disease, Neurocysticercosis, Ascariasis, Hookworm infection, Pinworm infection, Whipworm infection, Strongyloidiasis

📋 Drug Information

Generic Name(s)Albendazole (400mg/5ml)
Brand Namemedabzol 400mg oral drops
ManufacturerMedbionic Healthcare
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassANTI INFECTIVES
Action ClassAntiprotozoal agents
Route of AdministrationOral
StorageStore at room temperature (15-30°C) in a dry place, away from direct sunlight. Keep the container tightly closed. Do not freeze.
Shelf Life24 months from the date of manufacture.
WHO GuidelineThe World Health Organization recommends albendazole for deworming in endemic areas, often as part of mass drug administration programs. It is on the WHO Model List of Essential Medicines.
ICMR GuidelineThe Indian Council of Medical Research recommends albendazole for treatment of soil-transmitted helminthiasis and other parasitic infections as per national guidelines.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Take this medicine with a fatty meal to enhance absorption, especially for tissue infections.
2
Shake the bottle well before each use to ensure uniform suspension.
3
Use a proper measuring device to avoid under- or over-dosing.
4
Complete the full course as prescribed, even if symptoms improve.
5
Wash hands thoroughly after using the toilet and before eating to prevent reinfection.
6
Avoid alcohol while taking this medicine to reduce liver risk.
7
Report any unusual bruising, bleeding, or signs of infection to your doctor immediately.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅
Abdominal pain
This medicine is commonly prescribed for worm infections causing abdominal pain.
Likely Use
✅
Itching around anus
This medicine is used for pinworm infections which cause anal itching.
Likely Use
❌
Fever
This medicine is not a primary fever reducer.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionAlbendazole is poorly absorbed from the gastrointestinal tract due to its low aqueous solubility. Absorption is increased when taken with a fatty meal, which can enhance systemic availability. For intestinal infections, systemic absorption is not required for efficacy.
DistributionAlbendazole is widely distributed throughout the body, including into the liver, lungs, and cerebrospinal fluid. It crosses the blood-brain barrier to some extent, which is important for treating neurocysticercosis. It also distributes into hydatid cysts.
Protein BindingAlbendazole is approximately 70% bound to plasma proteins.
MetabolismAlbendazole undergoes extensive first-pass metabolism in the liver, primarily via cytochrome P450 enzymes (CYP3A4). Its major active metabolite is albendazole sulfoxide, which is responsible for systemic anthelmintic activity. Further metabolism yields inactive sulfone and other metabolites.
Half-LifeThe elimination half-life of albendazole sulfoxide is approximately 8 to 12 hours. The parent drug has a very short half-life due to rapid metabolism.
ExcretionAlbendazole and its metabolites are primarily excreted in the bile and then in feces. Only a small amount (less than 1%) is excreted unchanged in urine.
BioavailabilityOral bioavailability is low, approximately 5% or less, due to poor solubility and first-pass metabolism. It can be increased by administering with a fatty meal.
Onset of ActionThe onset of action varies depending on the infection. For intestinal worms, effects may be seen within 24 to 48 hours as worms are expelled. For tissue infections, clinical improvement may take days to weeks.
Peak Plasma TimePeak plasma concentration of the active metabolite albendazole sulfoxide is reached approximately 2 to 5 hours after oral administration.
Duration of ActionThe duration of action depends on the dosing regimen. For intestinal infections, a single dose may be sufficient. For tissue infections, treatment may last for weeks to months.

How It Works

Albendazole works by binding to beta-tubulin, a protein essential for the formation of microtubules in parasitic worms. This binding inhibits microtubule polymerization, which disrupts the worm's cellular structure and function. Specifically, it impairs glucose uptake in the worm, leading to depletion of glycogen stores and ultimately causing the worm's death. This medicine is effective against both intestinal and tissue-dwelling helminths.

Mechanism Steps

1
Binding to beta-tubulin: Albendazole binds selectively to the beta-tubulin subunit of parasitic worms, inhibiting microtubule assembly.
2
Disruption of microtubule function: This binding prevents the formation of microtubules, which are essential for cell division, motility, and nutrient transport.
3
Impaired glucose uptake: As a result, the worm cannot absorb glucose efficiently, leading to depletion of energy reserves.
4
Worm death: The worm eventually dies due to energy depletion and cellular damage, and is expelled from the body.

💡 How to Take medabzol 400mg oral drops

Strength: Oral drops: 400 mg per 5 ml

1Shake the bottle well before use.
2Use the provided dropper or measuring device to measure the exact dose.
3Take with food to enhance absorption and reduce stomach upset.
4Swallow the liquid directly or mix with a small amount of water if desired.
5Wash the dropper after use and close the bottle tightly.

Dosage Information

Adult DosageThe usual adult dose for intestinal worm infections is 400 mg as a single dose. For hydatid disease, the dose is 400 mg twice daily for 28 days, followed by a 14-day drug-free interval, and may be repeated for up to three cycles. For neurocysticercosis, 400 mg twice daily for 8-30 days is used. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function.
Pediatric DosageFor children over 2 years, the dose is typically 400 mg as a single dose for intestinal infections. For children 1-2 years, a reduced dose may be used. Pediatric dosing is not established from available information for all indications. Consult a pediatrician.
Elderly DosageNo specific dose adjustment is required for elderly patients, but caution is advised due to potential reduced hepatic or renal function. Dose must be individualized by a qualified clinician.
Renal ImpairmentNo specific dose adjustment is recommended for renal impairment, but caution is advised as the drug has not been extensively studied in this population.
Hepatic ImpairmentIn patients with hepatic impairment, albendazole should be used with caution. Dose adjustment may be necessary based on liver function tests. Consult a clinician.
Maximum Daily DoseThe maximum recommended daily dose is 800 mg (400 mg twice daily) for tissue infections. For intestinal infections, a single 400 mg dose is typical.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

Fatty meal
Take with food
Enhances absorption of albendazole.
Grapefruit juice
Avoid
May increase drug levels by inhibiting metabolism.

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of medabzol 400mg oral drops

✅ Common Side Effects

Stomach pain (Common (1-10%))
Take with food to reduce discomfort. If pain persists, consult your doctor.
Nausea (Common (1-10%))
Take with a meal. Avoid fatty foods if nausea worsens.
Vomiting (Common (1-10%))
Stay hydrated. If vomiting is severe or persistent, contact your doctor.
Headache (Common (1-10%))
Rest and stay hydrated. Consult doctor if headache is severe.
Dizziness (Common (1-10%))
Avoid driving or operating machinery until you know how this medicine affects you.

🚨 Serious Side Effects

Liver toxicity (hepatitis) (Rare (<0.1%))
Seek immediate medical attention if you notice yellowing of skin or eyes, dark urine, or severe abdominal pain.
Bone marrow suppression (Rare (<0.1%))
Report unusual bruising, bleeding, or signs of infection (fever, sore throat) to your doctor immediately.
Severe allergic reaction (anaphylaxis) (Very rare (<0.01%))
Call emergency services if you experience swelling of face, lips, throat, difficulty breathing, or rash.
Stevens-Johnson syndrome (Very rare (<0.01%))
Seek immediate medical care if you develop a painful rash with blisters, especially involving mouth, eyes, or genitals.

⚠️ Rare Side Effects

Pancreatitis
Seek medical attention if you have severe upper abdominal pain radiating to back.
Seizures
Call emergency services if seizures occur.
Vision changes
Consult an eye specialist if you notice blurred vision or vision loss.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Dexamethasone Major
Praziquantel Major
Cimetidine Moderate
Ritonavir Moderate
Grapefruit juice Minor

🚨 Major Interactions

  • Dexamethasone
  • Praziquantel

⚡ Moderate Interactions

  • Cimetidine
  • Ritonavir

🍷 Alcohol Interaction

Alcohol may increase the risk of liver toxicity and stomach upset. It is advisable to avoid alcohol while taking this medicine.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Known hypersensitivity to albendazole or benzimidazole derivatives","Pregnancy, especially first trimester","Breastfeeding without medical advice","Children under 1 year of age (unless specifically prescribed)","Severe liver disease"]

⚠️ Warnings & Precautions

["Use with caution in patients with liver impairment; dose adjustment may be needed.","Monitor for bone marrow suppression during prolonged high-dose therapy.","Avoid use in pregnancy unless clearly needed.","Do not use in patients with known hypersensitivity to albendazole.","May cause dizziness; avoid driving or operating machinery until you know how it affects you.","Complete the full course of treatment to prevent reinfection."]

🤱 Lactation Safety

Albendazole is excreted in breast milk in small amounts. It is generally not recommended during breastfeeding unless the benefit outweighs the risk. Consult your doctor before breastfeeding while on this medicine.

💊 Overdose Management

Overdose may cause nausea, vomiting, diarrhea, and abdominal pain. There is no specific antidote. Treatment is supportive and symptomatic. In case of overdose, seek immediate medical attention.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up.

Additional Safety Advice

General Safety

Take this medicine exactly as prescribed by your doctor. Do not take more or less than the recommended dose. It is usually taken with food to reduce stomach upset. Complete the full course even if you feel better. Wash your hands thoroughly after using the toilet and before eating to prevent reinfection. Avoid close contact with others who may have worm infections. If you are pregnant or planning pregnancy, inform your doctor before taking this medicine. Do not breastfeed while taking this medicine unless advised by your doctor.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients may have reduced liver or kidney function, so caution is advised. Dose adjustment may be necessary. Monitor for side effects.

🤰 Pregnancy Planning (TTC)

If you are planning pregnancy, consult your doctor before taking this medicine. It is not recommended during pregnancy, especially in the first trimester. Use effective contraception during treatment.

🏥 Post-Surgery Considerations

If you have recently had surgery, inform your surgeon about this medicine. It may affect liver function and interact with other medications.

🦷 Dental Procedures

Inform your dentist if you are taking this medicine. It may increase bleeding risk if you are also on blood thinners.

💚 Lifestyle Tips for Better Results

🏃
Wash your hands thoroughly with soap and water before eating and after using the toilet.
🥗
Keep your fingernails short and clean to prevent reinfection with pinworms.
😴
Wear shoes to prevent hookworm infection.
💧
Wash fruits and vegetables thoroughly before consumption.
🧘
Avoid walking barefoot in areas where hookworm is common.
🌞
Change and wash bed linens and underwear frequently if you have pinworms.

🏋️ Exercise Considerations

This medicine may cause dizziness. Avoid strenuous exercise or activities requiring alertness until you know how it affects you.

🥗 Diet Recommendations

Take with a fatty meal to enhance absorption.
Stay well hydrated.
Avoid alcohol.
Eat a balanced diet to support recovery.

💼 Impact on Daily Work & Life

This medicine may cause dizziness or headache. Avoid driving or operating heavy machinery until you know how it affects you. Most people can continue their daily activities with caution.

🛑 When to Stop This Medicine

Do not stop taking this medicine without consulting your doctor. Complete the full course as prescribed. If you experience serious side effects, contact your doctor immediately.

📅 Long-Term Use Effects

Long-term use of albendazole, especially at high doses for tissue infections, may require monitoring of liver function and blood counts. Prolonged use can rarely cause bone marrow suppression or liver toxicity. Regular follow-up with your doctor is essential.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Mebendazole

Another anti-worm medicine that can be used for similar infections.

Evidence: Well-established
Ivermectin

Used for certain parasitic infections, but not a direct substitute for all.

Evidence: Well-established for specific infections

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

There are no known interactions between albendazole and vaccines. However, consult your doctor before receiving any vaccine while on this medicine.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

Carry this medicine in its original packaging with a copy of your prescription. Store at room temperature and protect from direct sunlight. If traveling across time zones, adjust dosing schedule as advised by your doctor. Declare it at customs if required. Keep it in carry-on luggage to avoid temperature extremes.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 30-year-old mother noticed her 5-year-old child had itching around the anus and poor sleep.
The doctor prescribed this medicine as a single dose for the whole family. The child's symptoms resolved within a few days. The mother emphasized the importance of washing hands and changing underwear daily to prevent reinfection.
💡 Lesson: Pinworm infections often affect the whole family, and treating all members plus good hygiene prevents recurrence.
👤 A 45-year-old farmer presented with abdominal pain, weight loss, and fatigue.
Stool tests revealed hookworm infection. He was treated with this medicine, and his symptoms improved over two weeks. He was advised to wear shoes and improve sanitation to avoid reinfection.
💡 Lesson: Hookworm infections are common in areas with poor sanitation, and prevention through footwear and hygiene is key.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: For intestinal worms, effects may be seen within 24-48 hours as worms are expelled. For tissue infections, improvement may take days to weeks.

Q: Can I take it without food?

A: It is best taken with food, especially a fatty meal, to enhance absorption and reduce stomach upset.

Q: Is it safe for children?

A: It is generally safe for children over 2 years, but dose should be determined by a pediatrician.

Q: Can I take it during pregnancy?

A: It is not recommended during pregnancy, especially in the first trimester, unless clearly needed. Consult your doctor.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my liver function?
  • Can I drive after taking this medicine?
  • Does it interact with my other medicines?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?

🔄 Substitutes for medabzol 400mg oral drops

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: This medicine can be taken without a prescription.
    Fact: This medicine is a prescription drug and should only be taken under medical supervision.
  • Myth: It is safe to take during pregnancy.
    Fact: It is not recommended during pregnancy, especially in the first trimester, due to potential risk to the fetus.
  • Myth: One dose is enough for all worm infections.
    Fact: While a single dose may be sufficient for some intestinal worms, tissue infections require longer treatment.

🔄 Alternative Options

Generic Alternatives

  • Albendazole 400 mg oral suspension

Brand Alternatives

  • Zentel
  • Albenza
  • Eskazole

📊 Comparison with Similar Medicines

[{"medicine":"Albendazole","class":"Benzimidazole","spectrum":"Broad","single_dose_efficacy":"High for intestinal worms"},{"medicine":"Mebendazole","class":"Benzimidazole","spectrum":"Broad","single_dose_efficacy":"High for intestinal worms"},{"medicine":"Praziquantel","class":"Pyrazinoisoquinoline","spectrum":"Trematodes and cestodes","single_dose_efficacy":"High for schistosomiasis"}]

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