Maxof 500mg Tablet: Complete Guide to Uses, Side Effects, and Safety
When to Call Your Doctor IMMEDIATELY
- Sudden pain, swelling, or inability to move a joint (possible tendon rupture)
- Numbness, tingling, or burning in hands or feet (peripheral neuropathy)
- Seizures, severe confusion, or hallucinations
- Rash, hives, swelling of face or throat, difficulty breathing (anaphylaxis)
- Severe, persistent diarrhea with blood or mucus (C. difficile infection)
- Yellowing of skin or eyes, dark urine, right upper abdominal pain (hepatotoxicity)
- Irregular heartbeat, fainting, or palpitations (QT prolongation)
If experiencing severe symptoms, call emergency services immediately.
What is maxof 500mg tablet used for?
This medicine is an antibiotic used to treat bacterial infections such as urinary tract infections, respiratory infections, and skin infections. It works by stopping the growth of bacteria. It is not effective against viral infections.
- Generic Name: Ofloxacin (500mg)
- Manufacturer: Sri Biotech Pvt Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 maxof 500mg tablet के बारे में (Hindi Summary)
उपयोग: यह दवा ऑफ़्लोक्सासिन नामक एंटीबायोटिक है, जिसका उपयोग बैक्टीरियल संक्रमणों के इलाज के लिए किया जाता है। यह मूत्र मार्ग संक्रमण, श्वसन तंत्र संक्रमण, त्वचा संक्रमण, टाइफाइड बुखार और प्रोस्टेटाइटिस जैसी बीमारियों में प्रभावी है। यह दवा बैक्टीरिया के डीएनए को नष्ट करके उनकी वृद्धि को रोकती है। यह वायरल संक्रमण जैसे सर्दी-जुकाम के लिए प्रभावी नहीं है। इसका सेवन डॉक्टर के निर्देशानुसार ही करें।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में मतली, दस्त, सिरदर्द, चक्कर आना और पेट दर्द शामिल हैं। गंभीर दुष्प्रभाव दुर्लभ हैं, लेकिन इनमें टेंडन टूटना, तंत्रिका क्षति, दौरे, गंभीर एलर्जी और आंतों का संक्रमण हो सकता है। यदि आपको कोई असामान्य लक्षण दिखे तो तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। पूरा कोर्स पूरा करें, भले ही आप बेहतर महसूस करें। दवा लेते समय पर्याप्त पानी पिएं। एंटासिड, आयरन, कैल्शियम या जिंक सप्लीमेंट के साथ इस दवा को न लें; इन्हें 2 घंटे के अंतराल पर लें। धूप में जाने से बचें और सनस्क्रीन का उपयोग करें। शराब का सेवन न करें। यदि आपको चक्कर आते हैं तो वाहन न चलाएं।
💊 maxof 500mg tablet Uses & Benefits
[{"condition":"Urinary tract infections","description":"This medicine is effective against many bacteria causing uncomplicated and complicated UTIs, including cystitis and pyelonephritis.","evidence":"Well-established"},{"condition":"Respiratory tract infections","description":"Used for acute exacerbations of chronic bronchitis and community-acquired pneumonia caused by susceptible organisms.","evidence":"Well-established"},{"condition":"Skin and soft tissue infections","description":"Effective for cellulitis, abscesses, and wound infections caused by susceptible bacteria.","evidence":"Well-established"},{"condition":"Typhoid fever","description":"Used as an alternative to first-line agents for enteric fever caused by Salmonella typhi.","evidence":"Established"},{"condition":"Prostatitis","description":"Penetrates prostate tissue well and is used for chronic bacterial prostatitis.","evidence":"Established"},{"condition":"Gonorrhea","description":"Historically used but resistance is common; now often replaced by ceftriaxone.","evidence":"Limited due to resistance"}]
Off-label uses: [{"condition":"Atypical mycobacterial infections","description":"Sometimes used in combination regimens for Mycobacterium avium complex or other atypical mycobacteria.","evidence":"Limited"},{"condition":"Traveler's diarrhea","description":"May be used for severe traveler's diarrhea caused by susceptible bacteria.","evidence":"Limited"}]
Primary treatment for: Bacterial infections
Also treats: Urinary tract infections, Respiratory tract infections, Skin infections, Typhoid fever, Prostatitis
📋 Drug Information
| Generic Name(s) | Ofloxacin (500mg) |
| Brand Name | maxof 500mg tablet |
| Manufacturer | Sri Biotech Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | ANTI INFECTIVES |
| Action Class | Quinolones/ Fluroquinolones |
| Route of Administration | Oral |
| Storage | Store at room temperature between 15°C and 30°C (59°F to 86°F). Protect from light and moisture. Keep in a tightly closed container. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine exerts its antibacterial effect by inhibiting two key enzymes in bacteria: DNA gyrase (topoisomerase II) and topoisomerase IV. These enzymes are responsible for supercoiling and uncoiling of bacterial DNA during replication, transcription, and repair. By binding to these enzymes, this medicine blocks the re-ligation step of the DNA strand, leading to double-stranded DNA breaks and ultimately bacterial cell death. This action is bactericidal and concentration-dependent.
Mechanism Steps
💡 How to Take maxof 500mg tablet
Strength: 500 mg immediate-release tablet for oral administration.
Dosage Information
| Adult Dosage | The usual adult dose of this medicine for most infections is 200 mg to 400 mg taken orally every 12 hours, or 400 mg once daily, depending on the type and severity of infection. For uncomplicated urinary tract infections, 200 mg every 12 hours for 3 to 7 days is common. For respiratory tract infections, 400 mg every 12 hours for 7 to 14 days may be used. For typhoid fever, 400 mg every 12 hours for 7 to 14 days. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. This medicine is generally not recommended for children under 18 years of age due to risk of cartilage damage. |
| Elderly Dosage | Elderly patients may have reduced renal function and are at higher risk of tendon rupture and CNS effects. Dose should be adjusted based on renal function. Use with caution. |
| Renal Impairment | In patients with renal impairment (creatinine clearance <50 mL/min), dose adjustment is required. For creatinine clearance 20-50 mL/min, the usual dose is 200 mg every 24 hours. For creatinine clearance <20 mL/min, 200 mg every 48 hours or as directed by a clinician. Dose must be individualized by a qualified clinician. |
| Hepatic Impairment | No specific dose adjustment is generally required for hepatic impairment, as this medicine is minimally metabolized in the liver. However, use with caution in severe hepatic disease. |
| Maximum Daily Dose | The maximum recommended daily dose is 800 mg per day in divided doses for adults with normal renal function. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of maxof 500mg tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Antacids | Major | |
| Warfarin | Major | |
| Theophylline | Major | |
| NSAIDs | Major | |
| QT-prolonging drugs | Major | |
| Caffeine | Moderate | |
| Cyclosporine | Moderate | |
| Oral hypoglycemics | Moderate | |
| Probenecid | Moderate | |
| Iron supplements | Moderate |
🚨 Major Interactions
- Antacids, sucralfate, iron, zinc, calcium supplements
- Warfarin
- Theophylline
- NSAIDs (e.g., ibuprofen, naproxen)
- QT-prolonging drugs (e.g., amiodarone, sotalol, erythromycin)
⚡ Moderate Interactions
- Caffeine
- Cyclosporine
- Oral hypoglycemics
- Probenecid
🍷 Alcohol Interaction
Alcohol may increase the central nervous system side effects of this medicine, such as dizziness, drowsiness, and confusion. It is advisable to avoid alcohol while taking this medicine.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Known hypersensitivity to ofloxacin, other quinolones, or any component of the formulation","History of tendon disorders associated with fluoroquinolone use","Myasthenia gravis","Children under 18 years of age (unless specifically indicated)","Pregnancy and lactation (unless benefits outweigh risks)","Patients with a history of QT interval prolongation or uncorrected hypokalemia"]
⚠️ Warnings & Precautions
["Tendon rupture, including Achilles tendon, can occur; risk is increased in patients over 60, those on corticosteroids, and transplant recipients.","Peripheral neuropathy may occur and can be irreversible.","Central nervous system effects including seizures, confusion, and hallucinations have been reported.","May exacerbate muscle weakness in patients with myasthenia gravis.","Serious hypersensitivity reactions, including anaphylaxis, can occur.","Clostridioides difficile-associated diarrhea may occur; if suspected, discontinue and treat appropriately.","Avoid excessive sunlight and UV exposure due to photosensitivity risk.","May impair ability to drive or operate machinery; caution advised.","Use with caution in patients with renal impairment; dose adjustment may be needed.","Prolonged use may lead to overgrowth of non-susceptible organisms."]
🤱 Lactation Safety
This medicine is excreted in human breast milk. Because of the potential risk of serious adverse reactions in nursing infants, a decision should be made whether to discontinue nursing or to discontinue the medicine, taking into account the importance of the medicine to the mother.
💊 Overdose Management
There is no specific antidote for overdose with this medicine. In case of overdose, symptomatic and supportive treatment is recommended. Maintain adequate hydration to prevent crystalluria. Monitor ECG for QT prolongation. Activated charcoal may be considered if ingestion is recent. Contact a poison control center or emergency department immediately.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for a missed one.
Additional Safety Advice
Take this medicine exactly as prescribed by your doctor. Do not skip doses or stop treatment early, even if you feel better, as this can lead to recurrence of infection and antibiotic resistance. Take this medicine with plenty of water to prevent crystallization in urine. Avoid taking antacids, sucralfate, or mineral supplements containing iron, zinc, or calcium within 2 hours before or after taking this medicine, as they can reduce its absorption. Avoid alcohol while taking this medicine as it may increase dizziness and drowsiness. Use sunscreen and protective clothing when outdoors because this medicine can make your skin more sensitive to sunlight. Inform your doctor if you have kidney problems, epilepsy, or a history of tendon problems. Do not drive or operate heavy machinery if you experience dizziness or confusion. Complete the full course even if symptoms improve after a few days.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients are at higher risk of tendon rupture, CNS effects, and renal impairment. Dose adjustment based on renal function is necessary. Monitor closely for side effects.
🤰 Pregnancy Planning (TTC)
If you are planning to become pregnant, discuss with your doctor before taking this medicine. It is not recommended during pregnancy unless clearly needed. Use effective contraception while taking this medicine.
🏥 Post-Surgery Considerations
This medicine may be used to treat or prevent surgical site infections. Inform your surgeon if you are taking this medicine. It may interact with anesthetics and other medications used during surgery.
🦷 Dental Procedures
Inform your dentist if you are taking this medicine. It may interact with antibiotics used in dental procedures. No specific precautions are generally required, but maintain good oral hygiene.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Avoid strenuous exercise or activities that put stress on tendons while taking this medicine, as it increases the risk of tendon rupture. If you experience joint pain or swelling, stop exercising and consult your doctor.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause dizziness, drowsiness, or confusion, which can affect your ability to drive or operate machinery. Avoid these activities until you know how the medicine affects you. It is advisable to inform your employer if your work involves operating heavy machinery.
🛑 When to Stop This Medicine
Do not stop taking this medicine without consulting your doctor, even if you feel better. Stopping early can lead to recurrence of infection and antibiotic resistance. If you experience serious side effects, contact your doctor immediately; they may advise you to stop.
📅 Long-Term Use Effects
Long-term use of this medicine may lead to bacterial resistance and overgrowth of non-susceptible organisms. Rarely, it can cause persistent peripheral neuropathy, tendon damage, and CNS effects. Regular monitoring of renal and liver function may be required for prolonged therapy. Use only when prescribed and for the shortest duration necessary.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Depending on the infection and susceptibility, other antibiotics like ciprofloxacin, levofloxacin, or non-fluoroquinolones may be used.
Evidence: Well-establishedFor urinary tract infections, drinking plenty of water can help flush bacteria.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
This medicine may reduce the efficacy of live bacterial vaccines like typhoid vaccine. Avoid vaccination with live organisms during treatment. Consult your doctor for specific advice.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
When traveling, carry this medicine in its original packaging with a copy of your prescription. Keep it in your carry-on luggage to avoid temperature extremes. If crossing time zones, adjust dosing times gradually to maintain even intervals. Store at room temperature and protect from light and moisture. Check customs regulations for carrying prescription medicines.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: You may start feeling better within 2-3 days, but it is important to complete the full course as prescribed.
A: You can take it with or without food, but taking it with food may reduce stomach upset. Avoid dairy products within 2 hours of taking this medicine.
A: Avoid alcohol, antacids, mineral supplements, and excessive sun exposure. Do not drive if you feel dizzy.
A: This medicine is generally not recommended during pregnancy unless the benefits outweigh the risks. Consult your doctor.
🤔 Common Patient Concerns
🔄 Substitutes for maxof 500mg tablet
View AllAlternative brands with exact same active ingredient:
-
nirliv 500mg tabletNirlife Healthcare ₹1.25 98.4% CHEAPER
-
leozen 500mg tabletPCI Pharmaceuticals ₹4.68 94.1% CHEAPER
-
cipalgo 500mg tabletTerrace Pharmaceuticals ₹5.63 92.9% CHEAPER
-
adlox 500mg tabletAdley Formulations ₹7.50 90.6% CHEAPER
-
levopet 500mg tabletVista Health Care ₹7.50 90.6% CHEAPER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can cure the common cold.
Fact: This medicine is an antibiotic and is ineffective against viruses, including the common cold. - Myth: You can stop taking this medicine once you feel better.
Fact: You must complete the full prescribed course to prevent recurrence and resistance. - Myth: This medicine is safe for children.
Fact: This medicine is generally not recommended for children under 18 due to risk of joint and tendon damage. - Myth: This medicine can be taken with milk.
Fact: Milk and dairy products can reduce absorption of this medicine. Take with water instead.
🔄 Alternative Options
Generic Alternatives
- Ofloxacin 500 mg tablet
Brand Alternatives
- Oflox 500 mg tablet
- Zanocin 500 mg tablet
- Tarivid 500 mg tablet