Live Freeze Dried Lactic Acid Bacteria and Bifidobacteria (40Billion CFU)

🩺 Quick Overview

A high-potency, multi-strain probiotic formulation containing a minimum of 40 billion colony-forming units (CFU) of live, freeze-dried lactic acid bacteria (primarily Lactobacillus species) and Bifidobacteria. It is a biotherapeutic agent used to restore and maintain a healthy gut microbiota, crucial for digestive health, immune modulation, and metabolic functions. The freeze-drying process enhances long-term stability and viability of the bacteria.

Medical Uses

  • Acute infectious diarrhea (viral/bacterial) - adjunct to rehydration therapy
  • Antibiotic-associated diarrhea (prevention and treatment)
  • Irritable Bowel Syndrome (IBS) - for symptom relief (bloating, flatulence, abdominal discomfort)
  • Traveler's diarrhea (prophylaxis and treatment)

Side Effects

  • Mild bloating or gas during initial 3-5 days of therapy
  • Soft stools or mild constipation

💊 Dosage & Administration

Adult Dosage: One sachet/capsule containing 40 Billion CFU, once or twice daily, as directed. For acute diarrhea: Once or twice daily until resolution. For chronic conditions: Once daily for 4-8 weeks minimum.

Instructions: Take with or just after a meal to improve gastric acid survival. Mix sachet contents in cool/room temperature water, milk, or yogurt (not hot liquids). For capsules, swallow whole with water. If on antibiotics, take this probiotic at least 2-3 hours before or after the antibiotic dose.

🏭 Available Brands in India

PrePro-AB Sun Pharmaceutical Industries Ltd. VSL#3 Dr. Reddy's Laboratories (Marketed under license) Ecogut Mankind Pharma Ltd. Bifilac Tablets India Ltd. Probiocare Cipla Ltd.

Mechanism of Action

Exerts beneficial effects through multiple mechanisms: 1) Competitive Exclusion: Adheres to intestinal epithelium, outcompeting pathogenic bacteria for nutrients and binding sites. 2) Production of Antimicrobial Substances: Secretes bacteriocins, organic acids (lactic acid, acetic acid), and hydrogen peroxide that lower gut pH and inhibit pathogen growth. 3) Immunomodulation: Enhances gut barrier function by promoting mucin production and tight junction integrity. Modulates both innate and adaptive immune responses, promoting anti-inflammatory cytokine profiles (e.g., IL-10) and enhancing secretory IgA production. 4) Metabolic Activity: Ferments indigestible carbohydrates to produce SCFAs, which serve as an energy source for colonocytes and exert systemic anti-inflammatory effects.