A high-potency, multi-strain probiotic formulation containing a minimum of 40 billion colony-forming units (CFU) of live, freeze-dried lactic acid bacteria (primarily Lactobacillus species) and Bifidobacteria. It is a biotherapeutic agent used to restore and maintain a healthy gut microbiota, crucial for digestive health, immune modulation, and metabolic functions. The freeze-drying process enhances long-term stability and viability of the bacteria.
Adult: One sachet/capsule containing 40 Billion CFU, once or twice daily, as directed. For acute diarrhea: Once or twice daily until resolution. For chronic conditions: Once daily for 4-8 weeks minimum.
Note: Take with or just after a meal to improve gastric acid survival. Mix sachet contents in cool/room temperature water, milk, or yogurt (not hot liquids). For capsules, swallow whole with water. If on antibiotics, take this probiotic at least 2-3 hours before or after the antibiotic dose.
Exerts beneficial effects through multiple mechanisms: 1) Competitive Exclusion: Adheres to intestinal epithelium, outcompeting pathogenic bacteria for nutrients and binding sites. 2) Production of Antimicrobial Substances: Secretes bacteriocins, organic acids (lactic acid, acetic acid), and hydrogen peroxide that lower gut pH and inhibit pathogen growth. 3) Immunomodulation: Enhances gut barrier function by promoting mucin production and tight junction integrity. Modulates both innate and adaptive immune responses, promoting anti-inflammatory cytokine profiles (e.g., IL-10) and enhancing secretory IgA production. 4) Metabolic Activity: Ferments indigestible carbohydrates to produce SCFAs, which serve as an energy source for colonocytes and exert systemic anti-inflammatory effects.
Pregnancy: Category A (as per microbial supplements). Generally considered safe. Used to manage pregnancy-related constipation and gut health. However, product-specific data should be consulted; use under medical advice.
Driving: No effect. Safe.
| Antibiotics (e.g., Ciprofloxacin, Amoxicillin) | Antibiotics may kill the probiotic bacteria, reducing efficacy. Probiotics may help prevent antibiotic-associated side effects. | Moderate |
| Immunosuppressants (e.g., Cyclosporine, Tacrolimus, Azathioprine) | Theoretical increased risk of probiotic translocation and infection. Use with caution and under medical supervision. | Major |
| Antifungals (e.g., Fluconazole) | May affect yeast-based probiotics (Saccharomyces). Less interaction with bacterial strains. | Minor |