Lecsul 225mg/150mg Tablet: Complete Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Difficulty breathing or swelling of the face, lips, or throat
- Severe or bloody diarrhoea
- Yellowing of the skin or eyes
- Severe abdominal pain
- Unusual bleeding or bruising
- Decreased urine output
- Seizures or confusion
If experiencing severe symptoms, call emergency services immediately.
What is lecsul 225mg/150mg tablet used for?
This medicine is a combination antibiotic containing Ampicillin and Sulbactam. It is used to treat various bacterial infections by killing bacteria and preventing their resistance. It is taken orally, usually every 6 to 8 hours, and the full course must be completed as prescribed.
- Generic Name: Ampicillin (225mg) + Sulbactam (150mg)
- Manufacturer: Lexus Organics
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 lecsul 225mg/150mg tablet के बारे में (Hindi Summary)
उपयोग: यह दवा एम्पीसिलिन और सल्बैक्टम का संयोजन है, जिसका उपयोग विभिन्न जीवाणु संक्रमणों के इलाज के लिए किया जाता है। यह श्वसन तंत्र, मूत्र मार्ग, त्वचा और पेट के संक्रमणों में प्रभावी है। यह जीवाणुओं को मारकर और उनके प्रतिरोध को रोककर काम करती है। इसे डॉक्टर के निर्देशानुसार पूरा कोर्स करना आवश्यक है।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में दस्त, जी मिचलाना, उल्टी, पेट दर्द और त्वचा पर चकत्ते शामिल हैं। गंभीर दुष्प्रभाव दुर्लभ हैं, लेकिन एलर्जी, गंभीर दस्त, या यकृत की समस्या हो सकती है। किसी भी असामान्य लक्षण पर तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। कोर्स पूरा करें, बीच में न छोड़ें। गुर्दे या यकृत की बीमारी, या पेनिसिलिन से एलर्जी हो तो डॉक्टर को बताएं। अन्य दवाओं के साथ लेने से पहले डॉक्टर से सलाह लें। शराब से बचें। दवा को बच्चों से दूर रखें।
💊 lecsul 225mg/150mg tablet Uses & Benefits
[{"condition":"Respiratory tract infections","description":"Used to treat bacterial infections of the upper and lower respiratory tract, such as sinusitis, pharyngitis, and pneumonia, caused by susceptible organisms.","evidence":"Well-established"},{"condition":"Urinary tract infections","description":"Effective against many urinary tract infections caused by susceptible bacteria, including those producing beta-lactamases.","evidence":"Well-established"},{"condition":"Skin and soft tissue infections","description":"Used for treating cellulitis, abscesses, and wound infections caused by susceptible bacteria.","evidence":"Well-established"},{"condition":"Intra-abdominal infections","description":"Often used in combination with other antibiotics for intra-abdominal infections such as peritonitis and abscesses.","evidence":"Well-established"},{"condition":"Gynecological infections","description":"Used for pelvic inflammatory disease and other gynecological infections caused by susceptible organisms.","evidence":"Well-established"},{"condition":"Surgical prophylaxis","description":"Sometimes used to prevent surgical site infections in certain procedures.","evidence":"Well-established"}]
Off-label uses: [{"condition":"Lyme disease","description":"May be used off-label for early Lyme disease in some cases, but not a first-line option.","evidence":"Limited"},{"condition":"Anthrax","description":"Considered for post-exposure prophylaxis or treatment of anthrax in specific scenarios, but other agents are preferred.","evidence":"Limited"}]
Primary treatment for: Bacterial infections
Also treats: Respiratory tract infections, Urinary tract infections, Skin and soft tissue infections, Intra-abdominal infections, Gynecological infections
📋 Drug Information
| Generic Name(s) | Ampicillin (225mg) + Sulbactam (150mg) |
| Brand Name | lecsul 225mg/150mg tablet |
| Manufacturer | Lexus Organics |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | ANTI INFECTIVES |
| Action Class | |
| Route of Administration | Oral |
| Storage | Store at room temperature between 15°C and 30°C (59°F to 86°F). Protect from moisture and light. Keep in the original container. |
| Shelf Life | Typically 24 months from the date of manufacture, but check the expiry date on the packaging. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine combines Ampicillin, a penicillin antibiotic, with Sulbactam, a beta-lactamase inhibitor. Ampicillin works by binding to penicillin-binding proteins (PBPs) on the bacterial cell wall, inhibiting the final cross-linking step of peptidoglycan synthesis. This weakens the cell wall, leading to bacterial cell lysis and death. Sulbactam irreversibly inhibits certain beta-lactamase enzymes produced by bacteria, which would otherwise hydrolyze and inactivate Ampicillin. By blocking these enzymes, Sulbactam extends the spectrum of Ampicillin to include beta-lactamase-producing strains of Staphylococcus aureus, Haemophilus influenzae, Escherichia coli, and Klebsiella species, among others.
Mechanism Steps
💡 How to Take lecsul 225mg/150mg tablet
Strength: Each tablet contains Ampicillin 225 mg and Sulbactam 150 mg.
Dosage Information
| Adult Dosage | The usual adult dose of this medicine is one tablet taken orally every 6 to 8 hours, depending on the severity and type of infection. The exact dose and duration must be individualized by a qualified clinician based on the indication, age, weight, renal and hepatic function, and clinical response. Do not self-adjust the dose. Always complete the full course as prescribed. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician for appropriate dosing in children. |
| Elderly Dosage | Elderly patients may have reduced renal function, which can increase the risk of side effects. Dose adjustment may be necessary based on renal function. Consult a doctor for individualized dosing. |
| Renal Impairment | In patients with renal impairment, dose adjustment is required. For creatinine clearance (CrCl) between 15 and 29 mL/min, the dose may need to be reduced or the dosing interval extended. For CrCl less than 15 mL/min, the drug should be used with caution and may require further dose reduction. Consult a nephrologist or clinical pharmacist for guidance. |
| Hepatic Impairment | No specific dose adjustment is provided for hepatic impairment, but use with caution and monitor liver function. Consult a doctor for individualized dosing. |
| Maximum Daily Dose | The maximum daily dose should not exceed 4 tablets per day (total Ampicillin 900 mg and Sulbactam 600 mg) unless otherwise directed by a physician. In severe infections, higher doses may be prescribed under medical supervision. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of lecsul 225mg/150mg tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | |
| Methotrexate | Major | |
| Allopurinol | Major | |
| Probenecid | Major | |
| Oral contraceptives | Moderate | |
| Tetracyclines | Moderate | |
| Aminoglycosides | Moderate | |
| Antacids | Minor | |
| Food | Minor | |
| Alcohol | Minor |
🚨 Major Interactions
- Warfarin
- Methotrexate
- Allopurinol
- Probenecid
⚡ Moderate Interactions
- Oral contraceptives
- Tetracyclines
- Aminoglycosides
🍷 Alcohol Interaction
Alcohol may increase the risk of stomach upset and liver strain while taking this medicine. It is advisable to avoid alcohol during treatment.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Hypersensitivity to Ampicillin, Sulbactam, or any other penicillin or beta-lactam antibiotic","History of severe allergic reaction (e.g., anaphylaxis) to penicillins","Infectious mononucleosis (increased risk of rash)","Concurrent use with live typhoid vaccine"]
⚠️ Warnings & Precautions
["Before starting therapy, inquire about previous hypersensitivity reactions to penicillins, cephalosporins, or other allergens.","Serious and occasionally fatal hypersensitivity reactions (anaphylaxis) have been reported. Discontinue immediately if an allergic reaction occurs.","Clostridioides difficile-associated diarrhoea may occur during or after antibiotic therapy. If diarrhoea develops, evaluate for this condition.","Use with caution in patients with renal impairment; dose adjustment may be necessary.","Prolonged use may result in overgrowth of non-susceptible organisms, including fungi. Monitor for superinfections.","May interfere with certain laboratory tests, such as urine glucose tests and serum protein tests.","Not effective for viral infections. Do not use for colds or flu."]
🤱 Lactation Safety
Ampicillin and Sulbactam are excreted in small amounts in breast milk. They are generally considered compatible with breastfeeding, but monitor the infant for diarrhoea, thrush, or rash. Consult your doctor before breastfeeding while on this medicine.
💊 Overdose Management
Overdose may cause nausea, vomiting, diarrhoea, and electrolyte imbalances. In severe cases, neuromuscular excitability or seizures may occur, especially in patients with renal impairment. Treatment is symptomatic and supportive. Hemodialysis may be considered to remove Ampicillin and Sulbactam from the blood in severe cases. Contact a poison control center or emergency department immediately if overdose is suspected.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up.
Additional Safety Advice
Take this medicine exactly as prescribed by your doctor. Do not skip doses or stop the course early, even if you feel better, as this can lead to treatment failure and antibiotic resistance. Inform your doctor if you have kidney problems, liver problems, or a history of allergies, especially to penicillin or other antibiotics. Tell your doctor about all other medicines you are taking, including over-the-counter drugs and herbal supplements, as interactions may occur. Avoid alcohol while taking this medicine to reduce the risk of stomach upset and liver strain. If you develop a rash, itching, or difficulty breathing, stop the medicine and seek immediate medical help. Keep this medicine out of reach of children and store it as directed on the label.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients are more likely to have reduced kidney function, which can increase the risk of side effects. Dose adjustment may be necessary. Monitor renal function and watch for signs of toxicity.
🤰 Pregnancy Planning (TTC)
If you are planning to become pregnant, consult your doctor before taking this medicine. It is generally considered safe during pregnancy when needed, but always discuss the risks and benefits with your healthcare provider.
🏥 Post-Surgery Considerations
This medicine may be used to prevent or treat surgical site infections. Follow your surgeon's instructions regarding dosing and duration. Inform your surgeon if you have any allergies or kidney problems.
🦷 Dental Procedures
Inform your dentist if you are taking this medicine, as it may interact with other medications used during dental procedures. It may also be prescribed for dental infections, but ensure it is taken as directed.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
While taking this medicine, you can continue light to moderate exercise if you feel well. However, if you experience dizziness, fatigue, or stomach upset, avoid strenuous activities and rest. Consult your doctor before resuming intense workouts.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause dizziness or fatigue in some people. If affected, avoid driving or operating heavy machinery until you know how it affects you. Most people can continue their normal daily activities, but take precautions if you feel unwell.
🛑 When to Stop This Medicine
Stop taking this medicine only after completing the full prescribed course or if your doctor advises you to stop. If you experience a severe allergic reaction, stop immediately and seek emergency care. Do not stop early, as it may lead to recurrence of infection and resistance.
📅 Long-Term Use Effects
Long-term use of this medicine may lead to antibiotic resistance, fungal overgrowth, and rarely, liver or kidney problems. It is not intended for prolonged use unless under strict medical supervision. Regular monitoring of liver and kidney function may be required if used for extended periods.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Can help prevent antibiotic-associated diarrhoea when taken alongside antibiotics.
Evidence: ModerateFor symptom relief, but they do not treat the infection.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
This medicine may reduce the effectiveness of live bacterial vaccines, such as the typhoid vaccine. Avoid receiving live vaccines during and shortly after treatment. Consult your doctor for specific timing.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
When traveling, carry this medicine in its original packaging with a copy of your prescription. Keep it in your carry-on luggage to avoid temperature extremes. If crossing time zones, adjust dosing times gradually, but consult your doctor for specific advice. Ensure you have enough supply for your entire trip. Check customs regulations for carrying prescription medicines.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: You may start feeling better within 1 to 2 days, but it is important to complete the full course as prescribed.
A: Yes, you can take it with food if it upsets your stomach, but it is best taken on an empty stomach for optimal absorption.
A: Take it as soon as you remember, but if it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double dose.
A: It is generally considered safe when clearly needed, but consult your doctor for personalized advice.
A: It is advisable to avoid alcohol as it may increase stomach upset and liver strain.
🤔 Common Patient Concerns
🔄 Substitutes for lecsul 225mg/150mg tablet
View AllAlternative brands with exact same active ingredient:
-
stalcil 225mg/150mg tabletStallion Laboratories Pvt Ltd ₹355.00 1.4% COSTLIER
-
sultafit 375 tabletFitwel Pharmaceuticals Private Limited ₹415.00 18.6% COSTLIER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: Antibiotics can cure viral infections like the common cold.
Fact: This medicine is effective only against bacterial infections. It does not treat viral infections. - Myth: You can stop taking antibiotics once you feel better.
Fact: You must complete the full prescribed course to prevent recurrence and resistance, even if symptoms improve. - Myth: Antibiotics can be shared with others who have similar symptoms.
Fact: Never share antibiotics. They are prescribed for a specific infection and person. Sharing can lead to incorrect treatment and resistance.
🔄 Alternative Options
Generic Alternatives
- Ampicillin + Sulbactam generic tablets
Brand Alternatives
- Not established from the available information.