Labewell Injection: Complete Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Severe dizziness or fainting
- Very slow heart rate (below 50 beats per minute)
- Difficulty breathing or wheezing
- Chest pain or tightness
- Sudden swelling of face, lips, or throat
- Yellowing of skin or eyes
- Decreased urine output
- Severe nausea or vomiting
If experiencing severe symptoms, call emergency services immediately.
What is labewell injection used for?
This medicine is an injectable blood pressure medicine containing labetalol. It is used in hospitals to quickly lower dangerously high blood pressure. It works by relaxing blood vessels and slowing the heart. It is given only by healthcare professionals under close monitoring.
- Generic Name: Labetalol (5mg/ml)
- Manufacturer: Vhl Pharmaceuticals Private Limited
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 labewell injection के बारे में (Hindi Summary)
उपयोग: यह दवा लैबेटालोल नामक सक्रिय तत्व वाला एक इंजेक्शन है, जिसका उपयोग अस्पताल में खतरनाक रूप से बढ़े हुए रक्तचाप को तुरंत कम करने के लिए किया जाता है। इसे गर्भावस्था के दौरान गंभीर उच्च रक्तचाप, सर्जरी के दौरान रक्तचाप बढ़ने, और उन स्थितियों में भी दिया जा सकता है जब मरीज मुँह से दवा नहीं ले सकता। यह दवा रक्त वाहिकाओं को फैलाकर और हृदय की गति को धीमा करके रक्तचाप को कम करती है। यह दवा केवल डॉक्टर या प्रशिक्षित स्वास्थ्यकर्मी द्वारा ही दी जाती है, घर पर स्वयं नहीं लगाई जाती।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में चक्कर आना, हल्का सिर घूमना, थकान, जी मिचलाना, उल्टी, और सिर की त्वचा में झुनझुनी महसूस होना शामिल है। कुछ मरीजों को पसीना आना, चेहरा लाल होना, या दिल की धड़कन धीमी होना भी महसूस हो सकता है। गंभीर दुष्प्रभाव कम होते हैं, लेकिन बहुत कम रक्तचाप, बहुत धीमी हृदय गति, सांस लेने में कठिनाई, दिल की विफलता, और लीवर की क्षति हो सकती है। अगर कोई भी गंभीर लक्षण दिखे तो तुरंत डॉक्टर को बताएं।
सुरक्षा सलाह: यह दवा केवल अस्पताल या क्लिनिक में प्रशिक्षित स्वास्थ्यकर्मी द्वारा ही दी जानी चाहिए, जहाँ रक्तचाप और हृदय गति की निगरानी की जा सके। मरीज को इस दवा के बारे में अपनी सभी दवाओं और बीमारियों की जानकारी डॉक्टर को देनी चाहिए। अस्थमा, बहुत धीमी हृदय गति, हृदय रोग, या गंभीर लीवर रोग वाले मरीजों को यह दवा सावधानी से दी जानी चाहिए। गर्भवती महिलाओं को यह दवा केवल विशेषज्ञ की देखरेख में ही दी जानी चाहिए। इंजेक्शन के बाद चक्कर आ सकते हैं, इसलिए डॉक्टर के कहने तक गाड़ी न चलाएं और मशीन न चलाएं।
💊 labewell injection Uses & Benefits
[{"condition":"Hypertensive emergency","description":"This medicine is used to rapidly reduce severely elevated blood pressure when there is a risk of organ damage, such as in hypertensive encephalopathy, aortic dissection, or eclampsia.","evidence":"Well-established"},{"condition":"Severe hypertension in pregnancy","description":"It is commonly used in hospital settings to control dangerously high blood pressure in pregnant women, including those with pre-eclampsia or eclampsia.","evidence":"Well-established"},{"condition":"Perioperative hypertension","description":"This medicine may be used during or after surgery to manage sudden increases in blood pressure.","evidence":"Established"},{"condition":"Hypertension when oral therapy is not possible","description":"It can be used when a patient cannot take oral blood pressure medicines and needs parenteral treatment.","evidence":"Established"}]
Off-label uses: [{"condition":"Control of blood pressure in pheochromocytoma","description":"Sometimes used before surgery for pheochromocytoma to control blood pressure, but specialist supervision is required.","evidence":"Limited"},{"condition":"Management of clonidine withdrawal hypertension","description":"May be used in some emergency situations to manage severe high blood pressure after sudden withdrawal of clonidine.","evidence":"Limited"}]
Primary treatment for: Hypertensive emergency
Also treats: Severe hypertension in pregnancy, Perioperative hypertension, Hypertension when oral therapy is not possible
📋 Drug Information
| Generic Name(s) | Labetalol (5mg/ml) |
| Brand Name | labewell injection |
| Manufacturer | Vhl Pharmaceuticals Private Limited |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | CARDIAC |
| Action Class | Alpha & beta blocker |
| Route of Administration | Parenteral (intravenous injection or infusion) |
| Storage | Store this medicine in its original container at room temperature, between 15°C and 30°C. Protect it from light and do not freeze it. Keep it out of reach of children. |
| Shelf Life | The shelf life of this medicine is typically 24 months from the date of manufacture, but you should always check the expiry date on the label. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine works by blocking both alpha-1 and beta-adrenergic receptors in the body. Blocking alpha-1 receptors in the blood vessels causes them to relax and widen, which lowers blood pressure. Blocking beta receptors in the heart slows the heart rate and reduces the force of heart contractions, which further lowers blood pressure and decreases the heart's workload. This dual action makes it effective for rapid blood pressure control in emergency situations.
Mechanism Steps
💡 How to Take labewell injection
Strength: This medicine is available as a sterile injection containing labetalol 5 mg per mL. It is supplied in vials or ampoules for parenteral use.
Dosage Information
| Adult Dosage | The dose of this medicine is individualized by a qualified clinician based on the patient's condition, blood pressure, heart rate, and response to treatment. For hypertensive emergencies, a common starting dose is 20 mg given slowly into a vein over 2 minutes, followed by 40 to 80 mg every 10 minutes if needed, up to a maximum of 300 mg. Alternatively, an infusion may be started at 0.5 to 2 mg per minute and adjusted according to blood pressure. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients may be more sensitive to the blood pressure-lowering effects of this medicine. The dose should be started low and increased slowly under close monitoring. Dose must be individualized by a qualified clinician based on the patient's condition and kidney and liver function. |
| Renal Impairment | No specific dose adjustment is usually required for patients with kidney disease, but this medicine should be used with caution and blood pressure should be monitored closely. Dose must be individualized by a qualified clinician. |
| Hepatic Impairment | This medicine is metabolized in the liver, so patients with liver disease may need a lower dose and close monitoring. Dose must be individualized by a qualified clinician based on liver function. |
| Maximum Daily Dose | The maximum daily dose for intravenous use is 300 mg, but this may vary depending on the clinical situation. The dose must be determined by a qualified clinician. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of labewell injection
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Other beta-blockers | Major | |
| Verapamil | Major | |
| Diltiazem | Major | |
| Clonidine | Major | |
| Insulin | Major | |
| NSAIDs | Moderate | |
| Tricyclic antidepressants | Moderate | |
| Cimetidine | Moderate | |
| Nitroglycerin | Moderate | |
| Thyroid medicines | Moderate |
🚨 Major Interactions
- Other beta-blockers
- Calcium channel blockers (verapamil, diltiazem)
- Clonidine
- General anesthetics
- Insulin and oral antidiabetic drugs
⚡ Moderate Interactions
- Nonsteroidal anti-inflammatory drugs (NSAIDs)
- Tricyclic antidepressants
- Cimetidine
- Nitroglycerin
- Thyroid medicines
🍷 Alcohol Interaction
Alcohol can increase the blood pressure-lowering effect of this medicine and may cause excessive dizziness, light-headedness, and fainting. It is best to avoid alcohol while receiving this medicine and until your doctor says it is safe.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Severe slow heart rate (bradycardia)","Heart block greater than first degree","Cardiogenic shock","Severe heart failure","History of asthma or severe bronchospasm","Severe liver disease","Known allergy to labetalol or any component of this medicine"]
⚠️ Warnings & Precautions
["This medicine must be given only by a healthcare professional in a monitored setting.","It can cause a sudden drop in blood pressure, so patients should remain lying down during and after administration.","It can mask the symptoms of low blood sugar in diabetic patients.","It should be used with caution in patients with liver or kidney disease.","It should be used with caution in patients with a history of heart failure.","It should be used with caution in patients with asthma or other breathing problems.","It can interact with many other medicines, so the full list of medicines should be reviewed before use.","It should not be stopped suddenly without medical advice."]
🤱 Lactation Safety
This medicine passes into breast milk in small amounts. It is generally considered safe for breastfeeding when used short-term under medical supervision, but you should consult your doctor before breastfeeding while receiving this medicine.
💊 Overdose Management
Overdose of this medicine can cause severe low blood pressure, very slow heart rate, heart failure, and difficulty breathing. Treatment is supportive and may include intravenous fluids, medicines to raise blood pressure, and medicines to increase heart rate. In severe cases, hospitalization and intensive monitoring are required. If overdose is suspected, seek emergency medical help immediately.
⏰ Missed Dose
This medicine is given by a healthcare professional in a hospital or clinic setting, so missed doses are not applicable for self-administration. If you miss a scheduled dose, inform your healthcare provider as soon as possible. Do not attempt to take this medicine on your own.
Additional Safety Advice
This medicine must only be given by a trained healthcare professional in a setting where blood pressure, heart rate, and heart rhythm can be monitored continuously. Patients should tell the medical team about all other medicines they take, especially other blood pressure medicines, medicines for heart rhythm, and medicines that affect liver enzymes. People with asthma or other breathing problems, a very slow heart rate, certain heart blocks, or severe heart failure should not receive this medicine unless a specialist decides it is absolutely necessary. This medicine can mask the symptoms of low blood sugar in people with diabetes, so blood sugar should be checked regularly during treatment. Pregnant women should receive this medicine only when the benefit clearly outweighs the risk, and the baby's heart rate should be monitored. After treatment, the patient should not drive or operate machinery until the doctor confirms that blood pressure is stable and dizziness has resolved.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients may be more sensitive to the blood pressure-lowering effects of this medicine. The dose should be started low and increased slowly under close monitoring. Kidney and liver function should be checked regularly.
🤰 Pregnancy Planning (TTC)
If you are planning pregnancy and are taking this medicine, consult your doctor before conception. This medicine is used in pregnancy when the benefit outweighs the risk, but it should only be used under specialist supervision. Your doctor may adjust your treatment plan.
🏥 Post-Surgery Considerations
This medicine may be used during or after surgery to control blood pressure. After surgery, your blood pressure and heart rate will be monitored closely. Inform your surgeon and anesthesiologist if you have received this medicine.
🦷 Dental Procedures
Inform your dentist if you have received this medicine, especially if you are taking other blood pressure medicines. This medicine can interact with some medicines used in dental procedures, so your dentist may need to adjust your treatment.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
After receiving this medicine, you may feel dizzy or light-headed. Avoid strenuous exercise or sudden movements until your blood pressure is stable and your doctor says it is safe. Start with light activities and gradually increase as tolerated.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine is given in a hospital or clinic, so it may require you to stay for monitoring. After receiving it, you may feel dizzy or tired, so you should not drive or operate heavy machinery until your doctor confirms it is safe. You may need to take rest and avoid stressful activities for a short period.
🛑 When to Stop This Medicine
This medicine is usually stopped by the healthcare team once your blood pressure is stable and you can take oral medicines. Do not stop this medicine on your own. If you experience severe side effects, inform your doctor immediately; they will decide whether to stop or change the treatment.
📅 Long-Term Use Effects
This medicine is usually used for short-term treatment in emergency situations. Long-term use is not common. If used for a longer period, regular monitoring of blood pressure, heart rate, liver function, and kidney function is required. It should not be stopped suddenly without medical advice.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Once your condition is stable, you may be switched to oral medicines for long-term blood pressure control.
Evidence: Well-establishedDiet, exercise, and stress management can help control blood pressure in the long term.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
There are no specific vaccine interactions with this medicine. However, if you are scheduled for vaccination, inform your doctor that you are receiving this medicine. Your doctor will advise you on the timing.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate or freeze
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✅ DO
Check expiry date before use
❌ DON'T
Do not use if the solution is discolored or contains particles
✈️ Traveling with This Medicine
This medicine is given in a hospital or clinic setting, so travel advice is not applicable for self-administration. If you are traveling after receiving this medicine, carry a copy of your prescription and medical records. Inform your doctor before traveling, especially if you need ongoing blood pressure monitoring. Keep a list of your medicines with you at all times.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: When given intravenously, this medicine starts to lower blood pressure within 2 to 5 minutes.
A: It is given by a healthcare professional as an injection into a vein, usually in a hospital or emergency setting.
A: Common side effects include dizziness, nausea, vomiting, tiredness, and a tingling sensation in the scalp.
A: It is used in pregnancy when the benefit outweighs the risk, especially in emergency situations. It should only be used under specialist supervision.
A: No, this medicine must only be given by a trained healthcare professional in a monitored setting.
🤔 Common Patient Concerns
🔄 Substitutes for labewell injection
View AllAlternative brands with exact same active ingredient:
-
beta-l injectionWohltat Lifesciences ₹208.13 0.9% COSTLIER
-
labetal 20mg injectionH2H India Biotech Private Limited ₹208.13 0.9% COSTLIER
-
labeon 20 injectionStrathspey Labs Pvt Ltd ₹299.00 45% COSTLIER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can be taken at home like a regular blood pressure pill.
Fact: This medicine is an injection that must be given by a healthcare professional in a monitored setting. It is not for home use. - Myth: This medicine is safe for everyone with high blood pressure.
Fact: This medicine is not safe for people with certain heart, lung, or liver conditions. A doctor must decide if it is appropriate. - Myth: This medicine can be stopped suddenly without any problem.
Fact: Stopping this medicine suddenly can cause serious problems. It should only be stopped under medical supervision.
🔄 Alternative Options
Generic Alternatives
- Labetalol injection
Brand Alternatives
- Labewell Injection