K-Cit Oral Solution: Complete Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Muscle weakness or paralysis
- Irregular heartbeat or palpitations
- Severe nausea or vomiting that prevents you from keeping fluids down
- Confusion or difficulty concentrating
- Swelling of face, lips, or throat
- Blood in urine or severe flank pain
- Decreased urine output
If experiencing severe symptoms, call emergency services immediately.
What is krate syrup used for?
This medicine is an oral solution of citric acid and potassium citrate used to prevent and treat uric acid and cystine kidney stones by making urine less acidic. It is also used for distal renal tubular acidosis. It should be taken after meals and at bedtime with plenty of water, exactly as prescribed.
- Generic Name: Citric Acid (334mg/5ml) + Potassium Citrate (1100mg/5ml)
- Manufacturer: Zegchem
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 krate syrup के बारे में (Hindi Summary)
उपयोग: यह दवा सिट्रिक एसिड और पोटैशियम सिट्रेट का मिश्रण है जो पेशाब को कम अम्लीय बनाती है। इसका उपयोग यूरिक एसिड और सिस्टीन की पथरी को रोकने और उनके इलाज में किया जाता है। यह डिस्टल रीनल ट्यूबुलर एसिडोसिस में भी मदद करती है। इसे डॉक्टर के बताए अनुसार भोजन के बाद और रात को सोने से पहले पानी के साथ लें।
साइड इफेक्ट्स: आम दुष्प्रभावों में जी मिचलाना, उल्टी, दस्त, पेट में गड़बड़ी और स्वाद में कड़वाहट शामिल हैं। गंभीर दुष्प्रभावों में पोटैशियम का बढ़ना, मांसपेशियों में कमजोरी, अनियमित धड़कन और एलर्जी शामिल हो सकते हैं। अगर ऐसे लक्षण दिखें तो तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: इस दवा को डॉक्टर के निर्देशानुसार ही लें। इसे हमेशा भोजन के बाद और भरपूर पानी के साथ लें। पोटैशियम सप्लीमेंट या नमक के विकल्प बिना डॉक्टर की सलाह के न लें। नियमित रूप से खून और पेशाब की जांच कराते रहें। गुर्दे, हृदय या एड्रेनल की बीमारी हो तो डॉक्टर को बताएं।
💊 krate syrup Uses & Benefits
[{"condition":"Uric acid kidney stones","description":"This medicine helps dissolve and prevent uric acid stones by making urine less acidic.","evidence":"Well-established"},{"condition":"Cystine kidney stones","description":"It increases urine pH, which helps dissolve cystine stones and prevents new ones from forming.","evidence":"Well-established"},{"condition":"Distal renal tubular acidosis","description":"It corrects metabolic acidosis and helps prevent kidney stones and bone problems associated with this condition.","evidence":"Well-established"},{"condition":"Hyperuricosuria","description":"It reduces the risk of uric acid stone formation in people who excrete too much uric acid in urine.","evidence":"Moderate"},{"condition":"Chemotherapy-induced hyperuricemia","description":"Sometimes used to alkalinize urine and prevent uric acid precipitation during tumor lysis syndrome.","evidence":"Moderate"}]
Off-label uses: [{"condition":"Prevention of contrast-induced nephropathy","description":"Occasionally used off-label to alkalinize urine before certain imaging procedures, but evidence is limited.","evidence":"Limited"},{"condition":"Chronic metabolic acidosis in chronic kidney disease","description":"May be used off-label to correct mild metabolic acidosis in some patients with chronic kidney disease.","evidence":"Limited"}]
Primary treatment for: Kidney stones (uric acid and cystine)
Also treats: Distal renal tubular acidosis, Hyperuricosuria, Metabolic acidosis
📋 Drug Information
| Generic Name(s) | Citric Acid (334mg/5ml) + Potassium Citrate (1100mg/5ml) |
| Brand Name | krate syrup |
| Manufacturer | Zegchem |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | UROLOGY |
| Action Class | |
| Route of Administration | Oral |
| Storage | Store at room temperature (15-30°C) in a tightly closed container. Protect from direct sunlight and moisture. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine works by supplying citrate salts that are metabolized to bicarbonate in the body. Bicarbonate neutralizes excess acid, raising blood and urine pH. Potassium citrate also directly increases urinary citrate, which binds calcium and inhibits crystal formation. The combined effect reduces the risk of uric acid and cystine stone formation and helps correct metabolic acidosis.
Mechanism Steps
💡 How to Take krate syrup
Strength: Each 5 mL contains Citric Acid 334 mg and Potassium Citrate 1100 mg.
Dosage Information
| Adult Dosage | The usual adult dose is 15 to 30 mL of this oral solution mixed with a full glass of water or juice, taken after meals and at bedtime. The exact dose and frequency depend on the condition being treated, your urine pH, and your kidney function. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients may be more sensitive to the effects of this medicine, especially regarding potassium levels. Dose must be individualized by a qualified clinician based on renal function and other factors. |
| Renal Impairment | Use with caution in patients with renal impairment. Dose adjustment may be needed based on kidney function. Consult your doctor. |
| Hepatic Impairment | No specific dose adjustment is established for hepatic impairment. Consult your doctor. |
| Maximum Daily Dose | The maximum daily dose is 30 mL per day, but this may vary based on medical condition and doctor's prescription. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of krate syrup
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Spironolactone | Major | |
| Lisinopril | Major | |
| Potassium chloride | Major | |
| Aluminum hydroxide | Moderate | |
| Ascorbic acid | Moderate | |
| Lithium | Minor | |
| Amphetamine | Minor | |
| Methenamine | Moderate | |
| Salicylates | Moderate | |
| ACE inhibitors | Major |
🚨 Major Interactions
- Potassium-sparing diuretics (e.g., spironolactone, amiloride)
- ACE inhibitors and ARBs
- Potassium supplements
⚡ Moderate Interactions
- Antacids containing aluminum
- Urinary acidifiers (e.g., ascorbic acid, methenamine)
- Salicylates
🍷 Alcohol Interaction
Alcohol may worsen dehydration and increase the risk of stomach upset. It is best to avoid alcohol while taking this medicine.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Hyperkalemia","Severe renal impairment","Active urinary tract infection","Adrenal insufficiency","Severe dehydration","Potassium-restricted diet"]
⚠️ Warnings & Precautions
["Use with caution in patients with kidney disease.","Monitor potassium levels regularly.","Avoid potassium supplements.","Do not use if you have difficulty urinating.","Consult doctor before use in pregnancy or breastfeeding."]
🤱 Lactation Safety
It is not known whether this medicine passes into breast milk. Consult your doctor before breastfeeding.
💊 Overdose Management
Overdose can cause hyperkalemia, which may lead to muscle weakness, irregular heartbeat, and cardiac arrest. Seek immediate medical attention. Treatment includes stopping the medicine, monitoring potassium levels, and giving appropriate therapy as directed by a healthcare professional.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose.
Additional Safety Advice
Take this medicine exactly as prescribed by your doctor. Mix each dose with a full glass of water or juice as directed, and drink plenty of fluids throughout the day. Do not take potassium supplements or salt substitutes containing potassium unless your doctor approves. Avoid taking this medicine with antacids that contain aluminum or with certain diuretics that can raise potassium. Keep all follow-up appointments for blood and urine tests. Tell your doctor if you have kidney disease, heart disease, adrenal problems, or diabetes. Do not use this medicine if you are dehydrated or have a urinary tract infection without consulting your doctor. Store it properly and keep it out of reach of children.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients may be more prone to hyperkalemia and kidney problems. Regular monitoring of potassium and renal function is advised. Dose adjustment may be necessary.
🤰 Pregnancy Planning (TTC)
If you are planning pregnancy, consult your doctor before continuing this medicine. The safety in pregnancy is not well established, and your doctor will weigh the benefits and risks.
🏥 Post-Surgery Considerations
Inform your surgeon and anesthesiologist that you are taking this medicine. It may need to be temporarily stopped before surgery, especially if you have kidney or heart issues.
🦷 Dental Procedures
No specific precautions for dental procedures. However, inform your dentist about all medicines you take.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
There are no specific exercise restrictions while taking this medicine. However, if you experience muscle weakness or fatigue, avoid strenuous activities and consult your doctor.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine is unlikely to affect your ability to drive or operate machinery. However, if you experience dizziness or muscle weakness, avoid these activities until you feel better.
🛑 When to Stop This Medicine
Do not stop this medicine without consulting your doctor. Stopping suddenly may increase the risk of stone formation or worsen metabolic acidosis. Your doctor will decide when it is safe to stop based on your condition and test results.
📅 Long-Term Use Effects
Long-term use of this medicine is generally safe when monitored appropriately. Regular blood tests are needed to check potassium levels and kidney function. Prolonged high doses may increase the risk of hyperkalemia or metabolic alkalosis. Your doctor may adjust the dose based on your response and test results.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Drinking plenty of water helps prevent kidney stones and complements medicine.
Evidence: Well-establishedReducing purine-rich foods and sodium can help manage uric acid levels.
Evidence: Well-establishedAn alternative formulation for those who prefer tablets.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
No specific vaccine interactions are known. Continue routine vaccinations as recommended by your doctor.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
Carry this medicine in its original packaging with a copy of your prescription. Store it at room temperature and protect it from direct sunlight. If traveling across time zones, adjust your dosing schedule gradually in consultation with your doctor. Keep enough supply for your entire trip. Check customs regulations for carrying prescription medicines.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: This medicine starts alkalinizing urine within 1 to 2 hours after a dose. However, it may take several weeks to see full benefits in preventing stones.
A: Some medicines can interact with this product, especially those affecting potassium levels. Always inform your doctor about all medicines you take.
A: Consult your doctor if you are pregnant or planning pregnancy. The safety profile is not well established.
🤔 Common Patient Concerns
🔄 Substitutes for krate syrup
View AllAlternative brands with exact same active ingredient:
-
urotrate syrupNovaduo Pharma ₹53.63 44.5% CHEAPER
-
kyralizer syrupRadix Pharmaceuticals ₹60.94 36.9% CHEAPER
-
urizer syrupLaxter Pharmaceutical Pvt Ltd ₹73.13 24.3% CHEAPER
-
potrate syrupIntas Pharmaceuticals Ltd ₹87.85 9% CHEAPER
-
urikind-k solutionMankind Pharma Ltd ₹99.41 3% COSTLIER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can dissolve all types of kidney stones.
Fact: It is effective mainly for uric acid and cystine stones, not for calcium oxalate stones. - Myth: You can take this medicine without monitoring.
Fact: Regular blood and urine tests are needed to monitor potassium and pH levels. - Myth: This medicine is a painkiller.
Fact: It does not relieve pain; it works by altering urine chemistry.
🔄 Alternative Options
Generic Alternatives
- Potassium citrate and citric acid oral solution
Brand Alternatives
- K-Cit Oral Solution