kira-neo ear drop - Benzocaine (1% w/v) + Chloramphenicol (5% w/v) medicine

Dicimycin Ear Drop: Complete Guide to Uses, Dosage, and Safety

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🏭 Nutricorp Healthcare India Pvt Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Sep 25, 2026
📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Moderate for otitis externa; limited for other uses.
Reviewed by
SaathiMed Expert Panel | Sep 25, 2026

When to Call Your Doctor IMMEDIATELY

  • Sudden severe ear pain or hearing loss
  • Swelling, redness, or rash spreading around the ear
  • Bluish discoloration of lips, skin, or nails (possible methemoglobinemia)
  • Unusual tiredness, pale skin, easy bruising, or frequent infections (possible blood disorder)
  • Difficulty breathing or swelling of face, lips, or throat (allergic reaction)
  • Severe dizziness or spinning sensation
  • Fever with chills or worsening ear discharge

If experiencing severe symptoms, call emergency services immediately.

What is kira-neo ear drop used for?

This medicine is a prescription ear drop containing benzocaine (a pain reliever) and chloramphenicol (an antibiotic). It is used to treat bacterial infections of the outer ear canal and provides rapid pain relief. It should not be used if you have a perforated eardrum.

  • Generic Name: Benzocaine (1% w/v) + Chloramphenicol (5% w/v)
  • Manufacturer: Nutricorp Healthcare India Pvt Ltd
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 kira-neo ear drop के बारे में (Hindi Summary)

उपयोग: यह दवा कान की बूंदें हैं जिनमें बेंज़ोकेन और क्लोरैम्फेनिकॉल होते हैं। यह बाहरी कान के संक्रमण (ओटाइटिस एक्सटर्ना) के इलाज के लिए इस्तेमाल की जाती है। बेंज़ोकेन से कान का दर्द और खुजली तुरंत कम होती है, और क्लोरैम्फेनिकॉल बैक्टीरिया को मारता है। इसका इस्तेमाल डॉक्टर के निर्देशानुसार ही करें। अगर कान का पर्दा फटा हुआ है तो यह दवा नहीं डालनी चाहिए।

साइड इफेक्ट्स: आमतौर पर यह दवा सुरक्षित होती है, लेकिन कुछ लोगों को कान में हल्की जलन, खुजली या लालिमा हो सकती है। कभी-कभी चक्कर आना या सिरदर्द हो सकता है। बहुत कम मामलों में बेंज़ोकेन से खून में ऑक्सीजन की कमी (मेथेमोग्लोबिनेमिया) हो सकती है, जिसमें होंठ या त्वचा नीली पड़ सकती है। क्लोरैम्फेनिकॉल से खून की गंभीर बीमारी होने का बहुत कम खतरा होता है। अगर असामान्य थकान, पीलापन, आसान चोट लगना या बुखार हो, तो तुरंत डॉक्टर से मिलें।

सुरक्षा सलाह: इस दवा को सिर्फ कान में डालें, मुंह से न लें। डालने से पहले हाथ धोएं। बूंदें डालने से पहले शीशी को हाथों में गर्म करें। करवट लेकर लेटें, प्रभावित कान ऊपर की ओर रखें, और बूंदें डालने के बाद 3-5 मिनट तक लेटे रहें। ड्रॉपर की नोक को कान या किसी सतह से न छुएं। अगर कान का पर्दा फटा है तो यह दवा न डालें। 7 दिन से ज्यादा इस्तेमाल न करें। बच्चों की पहुंच से दूर रखें। गर्भवती या स्तनपान कराने वाली महिलाएं डॉक्टर से सलाह लें।

💡 Did You Know? Over 80% of the antiretroviral drugs used globally to combat AIDS are supplied by Indian pharmaceutical companies.

💊 kira-neo ear drop Uses & Benefits

[{"condition":"Acute otitis externa (swimmer's ear)","description":"Treats bacterial infection of the outer ear canal and provides rapid pain relief due to the local anaesthetic action of benzocaine.","evidence":"Well-established"},{"condition":"Chronic otitis externa","description":"Used when the ear canal is infected and painful, provided the eardrum is intact.","evidence":"Moderate"},{"condition":"Fungal otitis externa (as adjunct)","description":"Sometimes used when bacterial infection coexists with fungal infection, but not as sole therapy.","evidence":"Limited"}]

Off-label uses: [{"condition":"Pain relief after ear cleaning or foreign body removal","description":"May be used short-term to reduce discomfort after minor ear procedures, but only if the eardrum is intact.","evidence":"Limited"}]

Primary treatment for: Otitis externa (bacterial)

Also treats: Chronic otitis externa, Swimmer's ear

📋 Drug Information

Generic Name(s)Benzocaine (1% w/v) + Chloramphenicol (5% w/v)
Brand Namekira-neo ear drop
ManufacturerNutricorp Healthcare India Pvt Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassOTOLOGICALS
Action Class
Route of AdministrationOtic (into the ear canal)
StorageStore at room temperature (15-30°C). Protect from light and moisture. Keep the bottle tightly closed when not in use. Do not freeze.
Shelf Life24 months from the date of manufacture, unless otherwise stated on the packaging.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Always warm the ear drops in your hands before use to prevent dizziness from cold liquid entering the ear.
2
Do not touch the dropper tip to your ear or any surface to avoid contaminating the bottle.
3
Stay lying down for at least 3-5 minutes after applying the drops to ensure the medicine reaches the infection.
4
Do not use this medicine for more than 7 days without consulting your doctor, as prolonged use can lead to resistance or side effects.
5
If you have a perforated eardrum or a history of ear surgery, do not use this medicine unless specifically approved by your ENT specialist.
6
Keep water out of your ear during treatment; use earplugs while showering or swimming.
7
If symptoms do not improve within 3 days or worsen, contact your doctor promptly.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅
Ear pain
This medicine is commonly prescribed for ear pain due to bacterial infection.
Likely Use
✅
Ear itching
Benzocaine provides relief from itching.
Likely Use
❌
Fever
This medicine is not a primary fever reducer.
Not Primary
❌
Hearing loss
Hearing loss may indicate a more serious condition; consult a doctor.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionBenzocaine is absorbed through mucous membranes and broken skin, but systemic absorption from intact ear canal skin is minimal. Chloramphenicol can be absorbed through the skin and mucous membranes, especially if the skin is inflamed or damaged; however, systemic absorption from ear drops is generally low.
DistributionNot established from the available information.
Protein BindingBenzocaine binds to plasma proteins, but exact percentage is not established from the available information. Chloramphenicol is approximately 50-60% bound to plasma proteins.
MetabolismBenzocaine is metabolised in the liver by esterases and in the plasma by pseudocholinesterases to para-aminobenzoic acid and ethanol. Chloramphenicol is metabolised in the liver primarily by glucuronidation to chloramphenicol glucuronide.
Half-LifeBenzocaine has a short half-life of approximately 1 to 2 hours. Chloramphenicol has a half-life of approximately 1.5 to 4 hours in adults with normal liver function.
ExcretionBenzocaine metabolites are excreted mainly in urine. Chloramphenicol and its metabolites are excreted primarily in urine, with a small amount in bile and faeces.
BioavailabilityNot established from the available information for the ear drop formulation.
Onset of ActionBenzocaine provides pain relief within 1 to 5 minutes after application. Chloramphenicol begins to inhibit bacterial growth immediately, but noticeable improvement in infection symptoms usually takes 24 to 48 hours.
Peak Plasma TimeNot established from the available information for the ear drop formulation.
Duration of ActionBenzocaine numbness lasts approximately 30 to 60 minutes. Chloramphenicol's antibacterial effect persists as long as therapeutic levels are maintained in the ear canal, typically requiring dosing every 6 to 8 hours.

How It Works

This medicine works through two complementary mechanisms. Benzocaine is a local anaesthetic that blocks sodium channels in nerve endings, preventing pain signals from being transmitted to the brain. Chloramphenicol is a bacteriostatic antibiotic that binds to the 50S ribosomal subunit of bacteria and inhibits protein synthesis, thereby stopping bacterial growth and allowing the body's immune system to clear the infection.

Mechanism Steps

1
Benzocaine blocks sodium channels: Benzocaine reversibly binds to voltage-gated sodium channels on sensory nerve endings in the ear canal, preventing depolarisation and blocking pain signal transmission.
2
Rapid pain relief: This blockade results in numbness and relief from pain and itching within a few minutes of application.
3
Chloramphenicol enters bacteria: Chloramphenicol diffuses into bacterial cells and binds to the 50S subunit of the bacterial ribosome.
4
Protein synthesis inhibition: By binding to the 50S subunit, chloramphenicol prevents the addition of amino acids to the growing peptide chain, thereby inhibiting bacterial protein synthesis.
5
Bacterial growth stops: Without protein synthesis, bacteria cannot multiply, and the immune system can eliminate the remaining organisms.

💡 How to Take kira-neo ear drop

Strength: Ear drops containing benzocaine 1% w/v and chloramphenicol 5% w/v.

1Wash your hands thoroughly with soap and water.
2Warm the ear drop bottle by holding it in your hands for 1-2 minutes.
3Lie down on your side with the affected ear facing up.
4Gently pull the outer ear backward and upward to straighten the ear canal.
5Instill the prescribed number of drops into the ear canal without touching the dropper to the ear.
6Stay lying down for 3-5 minutes to allow the medicine to reach the infection.
7Replace the cap tightly and wash your hands again.
8Repeat for the other ear if directed by your doctor.

Dosage Information

Adult DosageThe usual adult dose is 2 to 3 drops instilled into the affected ear canal every 6 to 8 hours, or as directed by your doctor. The exact dose and duration depend on the severity of the infection and your response to treatment. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Do not use for more than 7 days without medical advice.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician. In general, this medicine is not recommended for children under 2 years unless specifically prescribed by a doctor.
Elderly DosageNo specific dose adjustment is required for elderly patients. However, elderly patients may be more susceptible to side effects. Use with caution and follow your doctor's instructions.
Renal ImpairmentNo specific dose adjustment is established for renal impairment. Since systemic absorption is low, dose adjustment is unlikely to be necessary. Consult your doctor if you have severe kidney disease.
Hepatic ImpairmentNo specific dose adjustment is established for hepatic impairment. Use with caution in patients with severe liver disease due to potential systemic absorption of chloramphenicol.
Maximum Daily DoseNot established from the available information. Follow your doctor's prescription.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

No specific food interactions
No restrictions
This medicine is applied locally in the ear and does not interact with food.

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of kira-neo ear drop

✅ Common Side Effects

Mild burning or stinging at application site (Common (5-10%))
Usually resolves within a few minutes. If it persists or is severe, consult your doctor.
Itching or redness around the ear (Common (5-10%))
May indicate irritation or allergy. Stop using and consult your doctor if it worsens.
Headache (Uncommon (1-5%))
Usually temporary. Stay hydrated and rest. Consult doctor if severe or persistent.
Dizziness (Uncommon (1-5%))
Avoid driving or operating machinery until it passes. If it continues, contact your doctor.

🚨 Serious Side Effects

Methemoglobinemia (benzocaine-induced) (Rare (<0.1%))
Seek immediate medical attention if you notice bluish lips, skin, or nails, shortness of breath, confusion, or rapid heartbeat.
Aplastic anaemia or bone marrow suppression (chloramphenicol-induced) (Very rare (<0.01%))
Stop using and seek immediate medical help if you develop unusual tiredness, pale skin, easy bruising, fever, or sore throat.
Severe allergic reaction (anaphylaxis) (Rare (<0.1%))
Seek emergency care if you experience swelling of face, lips, throat, difficulty breathing, or widespread rash.

⚠️ Rare Side Effects

Contact dermatitis
Stop using and consult a doctor. May need a different antibiotic ear drop.
Superinfection with resistant bacteria or fungi
Consult your doctor if symptoms worsen or new symptoms appear.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Aminoglycoside ear drops Major
Warfarin Moderate
Phenytoin Moderate
Sulfonylureas Moderate
Chemotherapy agents Major

🚨 Major Interactions

  • Other ototoxic drugs (e.g., aminoglycoside ear drops)
  • Bone marrow suppressants (e.g., chemotherapy agents)

⚡ Moderate Interactions

  • Warfarin
  • Phenytoin
  • Oral hypoglycaemics (sulfonylureas)

🍷 Alcohol Interaction

No specific interaction is established between this ear drop and alcohol. However, alcohol may worsen dizziness if you experience it as a side effect. It is advisable to limit alcohol consumption while using this medicine.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Perforated eardrum or history of ear surgery.","Known allergy to benzocaine, chloramphenicol, or any component.","History of bone marrow suppression or blood dyscrasias.","Children under 2 years of age (unless directed by a doctor).","Do not use for more than 7 days without medical advice."]

⚠️ Warnings & Precautions

["For external use only. Do not swallow.","Avoid contact with eyes.","Do not use if the ear canal is severely damaged or if there is a risk of eardrum perforation.","Stop use and consult a doctor if symptoms worsen or do not improve after 3 days.","Rarely, benzocaine can cause methemoglobinemia; seek immediate care if symptoms occur.","Chloramphenicol can rarely cause serious blood disorders; report any unusual tiredness, bruising, or fever.","Keep out of reach of children.","Do not share this medicine with others."]

🤱 Lactation Safety

It is not known whether benzocaine or chloramphenicol passes into breast milk in significant amounts after ear drop use. Consult your doctor before using this medicine while breastfeeding.

💊 Overdose Management

Overdose from ear drops is unlikely due to low systemic absorption. If accidental ingestion occurs, seek immediate medical attention. Symptoms of chloramphenicol overdose may include nausea, vomiting, and bone marrow suppression. Treatment is supportive and symptomatic.

⏰ Missed Dose

If you miss a dose, apply it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up.

Additional Safety Advice

General Safety

Use this medicine only in the ear, as directed by your doctor. Wash your hands before and after applying the drops. Warm the bottle in your hands for a minute before use to avoid dizziness from cold drops. Lie on your side with the affected ear facing up, gently pull the outer ear backward and upward to straighten the ear canal, and put the prescribed number of drops in. Stay lying down for 3 to 5 minutes so the medicine reaches the infection. Do not touch the dropper tip to your ear or any surface to avoid contamination. Do not use this medicine if your eardrum is perforated or if you have a history of blood disorders. Do not use it for more than 7 days unless your doctor tells you to. Keep it out of reach of children. If you are pregnant, planning pregnancy, or breastfeeding, tell your doctor before using this medicine. Avoid getting water in your ear during treatment. Do not drive or operate machinery if you feel dizzy after using the drops.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients may be more susceptible to side effects such as dizziness. Use with caution and follow your doctor's instructions. No specific dose adjustment is required.

🤰 Pregnancy Planning (TTC)

If you are planning pregnancy, consult your doctor before using this medicine. The safety of this medicine during pregnancy is not well established, though systemic absorption is low.

🏥 Post-Surgery Considerations

Do not use this medicine after ear surgery unless specifically prescribed by your surgeon. It may interfere with healing or cause complications.

🦷 Dental Procedures

No specific considerations for dental procedures. However, inform your dentist about all medicines you are using.

💚 Lifestyle Tips for Better Results

🏃
Keep your ears dry and clean.
🥗
Avoid inserting cotton swabs or other objects into the ear canal.
😴
Use earplugs while swimming or showering to prevent water entry.
💧
Avoid scratching or rubbing the ear.
🧘
Maintain a healthy diet rich in vitamins to support immune function.
🌞
Get adequate rest to help your body fight the infection.
🚭
Avoid using headphones or earbuds until the infection clears.

🏋️ Exercise Considerations

Avoid swimming and water sports until the infection clears. Other exercises are generally safe, but if you experience dizziness, avoid activities that require balance. Consult your doctor before resuming water activities.

🥗 Diet Recommendations

Stay well hydrated.
Include vitamin C-rich fruits and vegetables.
Avoid excessive sugar and processed foods.
Consume probiotic-rich foods if taking antibiotics orally (not applicable for ear drops).

💼 Impact on Daily Work & Life

This medicine may cause dizziness in some people. If affected, avoid driving or operating heavy machinery until you know how it affects you. Otherwise, it should not significantly impact your daily work routine.

🛑 When to Stop This Medicine

Stop using this medicine after the prescribed course is complete, or earlier if your doctor advises. If you experience any serious side effects, stop immediately and seek medical help. Do not stop prematurely even if symptoms improve, as this can lead to recurrence.

📅 Long-Term Use Effects

Prolonged use of this medicine beyond 7 days can increase the risk of bacterial resistance and rare side effects such as blood disorders from chloramphenicol. It should only be used for the prescribed duration. If long-term use is necessary, your doctor may monitor your blood counts. Do not use continuously without medical supervision.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Ciprofloxacin ear drops

Another antibiotic ear drop that may be used if you are allergic to chloramphenicol or have a perforated eardrum.

Evidence: Well-established
Warm compress

Applying a warm compress to the ear can help relieve pain temporarily.

Evidence: Limited
Oral antibiotics

For severe infections, oral antibiotics may be prescribed.

Evidence: Well-established

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

No specific vaccine interactions are known. However, if you are due for any vaccination, inform your doctor that you are using this medicine.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

Carry this medicine in its original packaging with a copy of your prescription. Keep it in your hand luggage to avoid temperature extremes. Store at room temperature and protect from direct sunlight. If travelling across time zones, continue your regular dosing schedule as close as possible. Declare it at customs if required. Do not use if the seal is broken or if the solution is discoloured.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 35-year-old swimmer with painful ear infection
Ravi developed severe ear pain and itching after swimming. His doctor prescribed this medicine. He used it as directed, warming the bottle first and lying on his side for 5 minutes after each dose. Within two days, the pain reduced significantly, and the infection cleared in a week.
💡 Lesson: Proper application technique and completing the full course are key to effective treatment.
👤 A 60-year-old with chronic ear infection
Mrs. Sharma had recurrent ear infections. She was prescribed this medicine but stopped using it after 3 days when the pain subsided. The infection returned. Her doctor explained the importance of completing the full course and avoiding water exposure. She followed the advice and has not had a recurrence since.
💡 Lesson: Stopping treatment early can lead to recurrence and antibiotic resistance.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: Pain relief from benzocaine occurs within 1-5 minutes. Infection symptoms usually start improving within 24-48 hours, but complete resolution may take 5-7 days.

Q: Can I use this medicine for my child?

A: Pediatric dosing is not established from available information. Consult a pediatrician. It is generally not recommended for children under 2 years unless prescribed.

Q: What should I do if I miss a dose?

A: If you miss a dose, apply it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose.

Q: Can I use this medicine if I have a perforated eardrum?

A: No, this medicine is contraindicated if you have a perforated eardrum or a history of ear surgery. Consult your doctor for alternative treatment.

Q: Are there any food restrictions?

A: No specific food restrictions are known. However, maintain a healthy diet to support recovery.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I use this medicine if I have a perforated eardrum?
  • How long can I use this medicine safely?
  • Is it safe for children?
  • Can I use it while pregnant or breastfeeding?
  • What if I miss a dose?
  • Can I swim while using this medicine?
  • Does it interact with other ear drops?

🔄 Substitutes for kira-neo ear drop

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: Ear drops can be used for any ear pain.
    Fact: Ear drops should only be used if the eardrum is intact and the pain is due to an outer ear infection. Using them with a perforated eardrum can cause serious problems.
  • Myth: You can stop using the drops as soon as the pain goes away.
    Fact: You should complete the full course as prescribed to prevent the infection from returning and to avoid antibiotic resistance.
  • Myth: More drops mean faster recovery.
    Fact: Using more than prescribed can increase the risk of side effects and does not speed up recovery.

🔄 Alternative Options

Generic Alternatives

  • Benzocaine + Chloramphenicol ear drops (generic)

Brand Alternatives

  • Dicimycin ear drop

📊 Comparison with Similar Medicines

[{"medicine":"This medicine","active_ingredients":"Benzocaine + Chloramphenicol","primary_use":"Bacterial otitis externa with pain","pain_relief":"Yes (benzocaine)","eardrum_perforation":"Contraindicated"},{"medicine":"Ciprofloxacin ear drops","active_ingredients":"Ciprofloxacin","primary_use":"Bacterial otitis externa","pain_relief":"No","eardrum_perforation":"May be used with caution"},{"medicine":"Neomycin + Polymyxin B + Hydrocortisone ear drops","active_ingredients":"Neomycin, Polymyxin B, Hydrocortisone","primary_use":"Bacterial otitis externa with inflammation","pain_relief":"No (hydrocortisone reduces inflammation)","eardrum_perforation":"Contraindicated"}]

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