ketorex bar - Ketoconazole (2% w/w) + Salicylic Acid (0.2% w/w) medicine

Ketorex Bar: Complete Medicine Guide

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🏭 Dermarex HealthCare India Pvt. Ltd. 📦 Varies by brand 💊 Allopathy 📅 Updated: Sep 26, 2026
🤰 Pregnancy Category Not classified by FDA letter categories. Topical ketoconazole and salicylic acid are generally considered low risk when used as directed, but consult a doctor before use. 📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Well-established for topical antifungal and keratolytic use.
Reviewed by
SaathiMed Expert Panel | Sep 26, 2026
🩺
Medically Fact-Checked & Clinically Verified by SaathiMed Clinical Review Board
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026

When to Call Your Doctor IMMEDIATELY

  • Severe allergic reaction: swelling of face, lips, throat, or difficulty breathing.
  • Signs of systemic toxicity: nausea, vomiting, ringing in ears, rapid breathing (if large amounts absorbed).
  • Severe skin irritation, blistering, or peeling.
  • No improvement after 4 weeks of consistent use.
  • Signs of secondary bacterial infection: increased pain, pus, warmth, or fever.
  • Yellowing of eyes or skin (jaundice) – rare but seek medical attention.

If experiencing severe symptoms, call emergency services immediately.

What is ketorex bar used for?

This medicine is a medicated bar containing ketoconazole 2% and salicylic acid 0.2%, used to treat fungal skin infections like dandruff, seborrheic dermatitis, and tinea versicolor. It works by killing fungi and softening scales. Apply as directed by your doctor, usually once or twice daily.

  • Generic Name: Ketoconazole (2% w/w) + Salicylic Acid (0.2% w/w)
  • Manufacturer: Dermarex HealthCare India Pvt. Ltd.
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 ketorex bar के बारे में (Hindi Summary)

उपयोग: यह दवा एक टॉपिकल एंटीफंगल और केराटोलिटिक बार है जिसमें कीटोकोनाज़ोल 2% और सैलिसिलिक एसिड 0.2% होता है। इसका उपयोग फंगल त्वचा संक्रमण जैसे डैंड्रफ, सेबोरहिक डर्मेटाइटिस, और टिनिया वर्सिकलर के इलाज के लिए किया जाता है। यह फंगस को मारता है और त्वचा की परत को नरम करता है। इसे डॉक्टर के निर्देशानुसार प्रभावित क्षेत्र पर लगाएं।

साइड इफेक्ट्स: आम दुष्प्रभावों में त्वचा में हल्की जलन, सूखापन, खुजली या जलन शामिल हैं। ये आमतौर पर अस्थायी होते हैं। गंभीर एलर्जी प्रतिक्रिया दुर्लभ है लेकिन अगर चेहरे, होंठ या गले में सूजन, सांस लेने में कठिनाई हो तो तुरंत डॉक्टर से मिलें।

सुरक्षा सलाह: केवल बाहरी उपयोग के लिए। आंखों, नाक, मुंह और श्लेष्मा झिल्ली के संपर्क से बचें। टूटी त्वचा पर न लगाएं। डॉक्टर के निर्देशानुसार ही उपयोग करें। गर्भावस्था या स्तनपान के दौरान डॉक्टर से सलाह लें। बच्चों की पहुंच से दूर रखें।

💡 Did You Know? The Indian pharmaceutical market is expected to reach $130 billion by 2030.

💊 ketorex bar Uses & Benefits

[{"condition":"Tinea versicolor (pityriasis versicolor)","description":"This medicine helps eliminate the Malassezia yeast that causes discolored patches on the skin, reducing scaling and itching.","evidence":"Well-established"},{"condition":"Seborrheic dermatitis of the scalp","description":"Reduces flaking, itching, and redness associated with seborrheic dermatitis by targeting Malassezia fungi and softening scales.","evidence":"Well-established"},{"condition":"Dandruff","description":"Controls flaking and itching of the scalp by reducing fungal overgrowth and promoting shedding of dead skin cells.","evidence":"Well-established"},{"condition":"Tinea corporis (ringworm of the body)","description":"May be used as an adjunctive topical treatment for mild cases, though duration and extent of use should be guided by a clinician.","evidence":"Moderate"}]

Off-label uses: [{"condition":"Seborrheic blepharitis","description":"Sometimes used off-label for eyelid margin scaling, but only under strict medical supervision due to risk of eye irritation.","evidence":"Limited"}]

Primary treatment for: Fungal skin infections

Also treats: Seborrheic dermatitis, Tinea versicolor, Dandruff

📋 Drug Information

Generic Name(s)Ketoconazole (2% w/w) + Salicylic Acid (0.2% w/w)
Brand Nameketorex bar
ManufacturerDermarex HealthCare India Pvt. Ltd.
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassDERMA
Action Class
Route of AdministrationTopical
StorageStore at room temperature (15–30°C). Protect from direct sunlight and moisture. Keep in the original packaging.
Shelf LifeRefer to the packaging for the expiry date. Do not use after the expiry date.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Apply this medicine to the affected area and leave it on for 3–5 minutes before rinsing, unless your doctor advises otherwise.
2
Use consistently as prescribed; do not skip doses, as this can lead to treatment failure.
3
Avoid using other topical products on the same area unless approved by your doctor.
4
If your condition does not improve after 2–4 weeks, consult your doctor for reassessment.
5
Keep the bar dry between uses to prevent it from dissolving prematurely.
6
Wash your hands thoroughly after handling the bar to avoid spreading the medication to other areas.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅
Scaly, itchy scalp
This medicine is commonly prescribed for dandruff and seborrheic dermatitis.
Likely Use
✅
Discolored patches on skin
May be used for tinea versicolor.
Likely Use
❌
Fever
This medicine is not a fever reducer.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionMinimal systemic absorption after topical application to intact skin. Absorption may increase with prolonged use, large surface area, or application to inflamed or broken skin.
DistributionNot established from the available information.
Protein BindingKetoconazole is highly protein-bound (>99%) in plasma when absorbed systemically; however, topical absorption is minimal. Salicylic acid binds to plasma proteins when absorbed.
MetabolismKetoconazole is metabolized in the liver primarily by CYP3A4. Salicylic acid is metabolized in the liver by conjugation with glycine and glucuronic acid.
Half-LifeNot established from the available information for topical use. Systemic ketoconazole half-life is approximately 2 hours; salicylic acid half-life is dose-dependent.
ExcretionSystemically absorbed ketoconazole is excreted mainly in bile and feces, with a small portion in urine. Salicylic acid metabolites are excreted in urine.
BioavailabilityNot established from the available information for topical application. Systemic bioavailability of ketoconazole from topical formulations is negligible.
Onset of ActionImprovement in scaling and itching may begin within a few days; full therapeutic effect may take 2–4 weeks depending on the condition.
Peak Plasma TimeNot established from the available information for topical use.
Duration of ActionThe effect persists between applications; clinical improvement continues with regular use as prescribed.

How It Works

Ketoconazole inhibits the fungal cytochrome P450 enzyme 14α-demethylase, blocking the conversion of lanosterol to ergosterol, a key component of the fungal cell membrane. This leads to increased membrane permeability and fungal cell death. Salicylic acid is a beta-hydroxy acid that disrupts corneocyte cohesion, promoting desquamation of hyperkeratotic skin and facilitating penetration of ketoconazole.

Mechanism Steps

1
Ketoconazole uptake: Ketoconazole penetrates the fungal cell wall and membrane, reaching the intracellular target.
2
CYP51 inhibition: Ketoconazole binds to and inhibits fungal cytochrome P450 14α-demethylase, blocking ergosterol synthesis.
3
Membrane disruption: Depletion of ergosterol and accumulation of toxic sterol precursors increase membrane permeability, leading to fungal growth inhibition or death.
4
Salicylic acid keratolysis: Salicylic acid disrupts intercellular cohesion in the stratum corneum, promoting shedding of scales and improving penetration of ketoconazole.

💡 How to Take ketorex bar

Strength: Ketoconazole 2% w/w + Salicylic acid 0.2% w/w topical bar

1Wet the affected area with water.
2Apply the bar and lather gently.
3Leave the lather on the skin or scalp for 3–5 minutes.
4Rinse thoroughly with water.
5Pat dry gently.
6Wash hands after use.

Dosage Information

Adult DosageApply this medicine to the affected area as directed by your doctor, usually once or twice daily. The frequency and duration depend on the condition being treated. For scalp conditions, lather into wet hair and scalp, leave on for 3–5 minutes, then rinse thoroughly. Dose must be individualized by a qualified clinician based on indication, age, and response to treatment.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageNo specific dose adjustments are required for elderly patients when used topically as directed. However, elderly individuals may have thinner skin and should use with caution.
Renal ImpairmentNo dose adjustment needed for topical use. If significant systemic absorption occurs, consult a doctor.
Hepatic ImpairmentNo dose adjustment needed for topical use. If significant systemic absorption occurs, consult a doctor.
Maximum Daily DoseNot established from the available information. Use as prescribed by a clinician.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Apply the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of ketorex bar

✅ Common Side Effects

Application site irritation (Common (1-10%))
Usually resolves on its own. If persistent or severe, discontinue and consult your doctor.
Dryness or flaking (Common (1-10%))
May reduce with less frequent use. Consult doctor if bothersome.
Itching (Common (1-10%))
Avoid scratching. If itching worsens, stop use and seek medical advice.
Burning sensation (Uncommon (0.1-1%))
Rinse with water if severe. Consult doctor if it persists.

🚨 Serious Side Effects

Severe allergic reaction (anaphylaxis) (Rare (<0.1%))
Seek immediate medical attention if you experience swelling of face, lips, throat, difficulty breathing, or severe rash.
Contact dermatitis (Rare (<0.1%))
Discontinue use and consult a doctor if you develop severe redness, blistering, or peeling.

⚠️ Rare Side Effects

Systemic effects from absorption (e.g., nausea, headache)
Report to your doctor if you experience unusual symptoms.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Warfarin Minor
Other topical keratolytics Moderate

🚨 Major Interactions

  • Oral anticoagulants (e.g., warfarin)

⚡ Moderate Interactions

  • Other topical keratolytics (e.g., urea, alpha-hydroxy acids)

🍷 Alcohol Interaction

No known interaction with alcohol when used topically. However, alcohol consumption may worsen certain skin conditions; consult your doctor.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Known hypersensitivity to ketoconazole, salicylic acid, or any component of the formulation","Application to broken or inflamed skin","Use in eyes or mucous membranes"]

⚠️ Warnings & Precautions

["For external use only.","Avoid contact with eyes, nose, mouth, and other mucous membranes.","Do not use on large areas or for prolonged periods without medical advice.","Discontinue if severe irritation or allergic reaction occurs.","Consult a doctor before use in pregnancy or breastfeeding.","Keep out of reach of children."]

🤱 Lactation Safety

It is not known whether topical ketoconazole or salicylic acid is excreted in breast milk in significant amounts. Consult a doctor before use, especially if applying to the breast area.

💊 Overdose Management

Overdose from topical use is unlikely. If accidental ingestion occurs, seek immediate medical attention. Symptoms of salicylate toxicity may include nausea, vomiting, tinnitus, and hyperventilation. Treatment is supportive and symptomatic.

⏰ Missed Dose

If you miss a dose, apply it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up.

Additional Safety Advice

General Safety

For external use only. Avoid contact with eyes, nose, mouth, and other mucous membranes. If accidental contact occurs, rinse thoroughly with water. Do not apply to open wounds, cuts, or severely inflamed skin. Use this medicine exactly as prescribed by your doctor. Do not cover the treated area with airtight dressings unless instructed. Wash your hands before and after application. Keep out of reach of children. If you are pregnant, planning to become pregnant, or breastfeeding, consult your doctor before using this product. Do not use for longer than recommended without medical supervision. If symptoms worsen or do not improve after the prescribed course, seek medical advice.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients may have thinner, more sensitive skin. Use with caution and monitor for irritation.

🤰 Pregnancy Planning (TTC)

Consult your doctor before use if you are planning pregnancy. Topical ketoconazole and salicylic acid are generally considered low risk, but medical advice is recommended.

🏥 Post-Surgery Considerations

Avoid applying to surgical wounds or broken skin unless approved by your surgeon.

🦷 Dental Procedures

No specific considerations for dental procedures. Inform your dentist about all medications you are using.

💚 Lifestyle Tips for Better Results

🏃
Keep the affected area clean and dry.
🥗
Avoid sharing towels, combs, or clothing to prevent spread.
😴
Wear loose, breathable clothing to reduce sweating.
💧
Manage stress, as it can worsen skin conditions.
🧘
Follow a balanced diet rich in vitamins and minerals.

🏋️ Exercise Considerations

No specific exercise restrictions. However, if you sweat heavily, rinse and dry the area after exercise to prevent irritation.

🥗 Diet Recommendations

Include probiotics like yogurt to support skin health.
Reduce sugar and processed foods that may promote fungal growth.
Stay hydrated to maintain skin moisture.

💼 Impact on Daily Work & Life

This medicine is applied topically and is unlikely to affect your ability to drive or operate machinery. You can continue normal activities.

🛑 When to Stop This Medicine

Stop use and consult your doctor if you experience severe irritation, allergic reaction, or if your condition worsens. Do not stop prematurely without medical advice, as fungal infections may recur.

📅 Long-Term Use Effects

Long-term use of topical ketoconazole and salicylic acid is generally safe when used as directed. However, prolonged use over large areas may increase systemic absorption. Monitor for skin irritation and consult your doctor for periodic review.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Ketoconazole 2% shampoo

Alternative for scalp conditions; may be easier to apply.

Evidence: Well-established
Selenium sulfide shampoo

Another antifungal option for dandruff and tinea versicolor.

Evidence: Well-established

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

No known interaction with vaccines. Continue routine vaccinations as scheduled.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

Carry this medicine in its original packaging with a copy of your prescription. Store at room temperature and protect from direct sunlight and moisture. No time zone adjustments are needed for topical use. If traveling to areas with high humidity, keep the bar dry. Declare it if required by customs.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 32-year-old man with persistent dandruff and scalp itching.
He was prescribed this medicine to use twice weekly. After 3 weeks, his flaking and itching significantly reduced. He noted that leaving the lather on for 5 minutes made a difference.
💡 Lesson: Consistent use and proper application technique improve outcomes.
👤 A 45-year-old woman with tinea versicolor on her back.
She used this medicine daily for 4 weeks as directed. The patches gradually faded and scaling stopped. She experienced mild dryness initially, which resolved with a moisturizer.
💡 Lesson: Complete the full course even if symptoms improve early to prevent recurrence.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: You may notice improvement in scaling and itching within a few days, but full effect may take 2–4 weeks.

Q: Can I use it every day?

A: Use as directed by your doctor. Typically once or twice daily, but frequency depends on your condition.

Q: Is it safe for children?

A: Pediatric dosing is not established. Consult a pediatrician before use.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I use this medicine on my face?
  • How long should I use this medicine?
  • Is it safe to use during pregnancy?
  • Can I use it with other skincare products?
  • What if I miss a dose?
  • Does it cause hair loss?

🛑 Myths vs. Facts

  • Myth: Ketorex Bar can be used for any skin rash.
    Fact: It is specifically for fungal infections and should not be used for other rashes without medical advice.
  • Myth: You can stop using it as soon as symptoms improve.
    Fact: Complete the full course as prescribed to prevent recurrence.

🔄 Alternative Options

Generic Alternatives

  • Ketoconazole 2% + Salicylic acid 0.2% topical bar

📊 Comparison with Similar Medicines

[{"medicine":"Ketoconazole 2% + Salicylic acid 0.2% bar","active_ingredient":"Ketoconazole + Salicylic acid","form":"Bar","primary_use":"Fungal skin infections with scaling"},{"medicine":"Ketoconazole 2% shampoo","active_ingredient":"Ketoconazole","form":"Shampoo","primary_use":"Dandruff, seborrheic dermatitis"},{"medicine":"Selenium sulfide 2.5% shampoo","active_ingredient":"Selenium sulfide","form":"Shampoo","primary_use":"Dandruff, tinea versicolor"}]

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