Ketnix BT Cream: Complete Guide to Uses, Side Effects, and Safety
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Severe allergic reaction: swelling of face, lips, throat, difficulty breathing.
- Signs of adrenal suppression: extreme fatigue, weakness, weight loss, low blood pressure.
- Severe skin irritation: intense burning, blistering, or peeling.
- Signs of secondary infection: increased redness, swelling, pus, or pain.
- No improvement after 4 weeks of use.
- Symptoms worsen despite treatment.
If experiencing severe symptoms, call emergency services immediately.
What is ketonid-b cream used for?
This medicine is a topical cream containing beclometasone (a steroid) and ketoconazole (an antifungal). It is used to treat inflamed fungal skin infections like ringworm, athlete's foot, and jock itch. Apply a thin layer to the affected area as directed by your doctor, usually once or twice daily. Do not use for more than 4 weeks without medical advice.
- Generic Name: Beclometasone (0.25% w/w) + Ketoconazole (2% w/w)
- Manufacturer: Nidus Pharma Pvt Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 ketonid-b cream के बारे में (Hindi Summary)
उपयोग: यह दवा एक टॉपिकल क्रीम है जिसमें बेक्लोमेथासोन (एक स्टेरॉयड) और कीटोकोनाज़ोल (एक एंटीफंगल) शामिल हैं। इसका उपयोग फंगल संक्रमण के कारण होने वाली सूजन, खुजली और लालिमा के इलाज के लिए किया जाता है, जैसे दाद, एथलीट फुट, और जॉक इच। यह क्रीम फंगस को मारती है और सूजन को कम करती है। इसे डॉक्टर के निर्देशानुसार प्रभावित त्वचा पर पतली परत में लगाएं।
साइड इफेक्ट्स: आम दुष्प्रभावों में लगाने की जगह पर हल्की जलन, खुजली, या लालिमा शामिल हैं। ये आमतौर पर अस्थायी होते हैं। गंभीर दुष्प्रभाव दुर्लभ हैं, लेकिन एलर्जी, त्वचा का पतला होना, या संक्रमण बढ़ना हो सकता है। अगर कोई गंभीर लक्षण दिखे तो डॉक्टर से संपर्क करें।
सुरक्षा सलाह: इस दवा को केवल प्रभावित त्वचा पर ही लगाएं। आंखों, मुंह और अन्य श्लेष्मा झिल्ली से बचें। बिना डॉक्टर की सलाह के 4 सप्ताह से अधिक इस्तेमाल न करें। गर्भवती या स्तनपान कराने वाली महिलाएं डॉक्टर से सलाह लें। बच्चों की पहुंच से दूर रखें।
💊 ketonid-b cream Uses & Benefits
[{"condition":"Tinea corporis (ringworm) with inflammation","description":"Treats fungal infection of the body while reducing associated redness and itching.","evidence":"Well-established"},{"condition":"Tinea cruris (jock itch) with inflammation","description":"Treats fungal infection of the groin area and relieves inflammatory symptoms.","evidence":"Well-established"},{"condition":"Tinea pedis (athlete's foot) with inflammation","description":"Treats fungal infection of the feet and reduces swelling and itching.","evidence":"Well-established"},{"condition":"Seborrheic dermatitis with fungal component","description":"Reduces inflammation and controls Malassezia yeast on the skin.","evidence":"Moderate"},{"condition":"Candidal skin infections with inflammation","description":"Treats Candida fungal infections of the skin and relieves inflammation.","evidence":"Moderate"}]
Off-label uses: [{"condition":"Diaper dermatitis with fungal infection","description":"Sometimes used off-label for inflamed diaper rash with fungal involvement.","evidence":"Limited"},{"condition":"Intertrigo with fungal infection","description":"May be used for skin fold infections with inflammation and fungus.","evidence":"Limited"}]
Primary treatment for: Fungal skin infections with inflammation
Also treats: Tinea corporis, Tinea cruris, Tinea pedis, Seborrheic dermatitis, Candidal skin infections
📋 Drug Information
| Generic Name(s) | Beclometasone (0.25% w/w) + Ketoconazole (2% w/w) |
| Brand Name | ketonid-b cream |
| Manufacturer | Nidus Pharma Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | DERMA |
| Action Class | |
| Route of Administration | Topical |
| Storage | Store below 30°C. Protect from light and moisture. Do not freeze. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine combines a corticosteroid and an antifungal. Beclometasone binds to glucocorticoid receptors in the skin, reducing the production of inflammatory mediators and suppressing immune responses, which decreases redness, swelling, and itching. Ketoconazole inhibits the fungal enzyme cytochrome P450 14α-demethylase, blocking the synthesis of ergosterol, a key component of fungal cell membranes. This leads to increased membrane permeability and fungal cell death. Together, they address both the fungal infection and the inflammatory response.
Mechanism Steps
💡 How to Take ketonid-b cream
Strength: Cream containing beclometasone 0.25% w/w and ketoconazole 2% w/w.
Dosage Information
| Adult Dosage | Apply a thin layer to the affected area once or twice daily, or as directed by your doctor. The duration of treatment depends on the condition and response. Typically, treatment should not exceed 4 weeks without medical review. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | No specific dosage adjustments are required for elderly patients. However, they may be more susceptible to side effects. Use with caution and monitor for skin thinning and adrenal suppression. |
| Renal Impairment | No dosage adjustment is required for renal impairment when used topically. However, consult your doctor. |
| Hepatic Impairment | No dosage adjustment is required for hepatic impairment when used topically. However, use with caution in severe liver disease. |
| Maximum Daily Dose | Not established from the available information. Use only as prescribed. |
Dosage Timeline
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of ketonid-b cream
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | |
| Ritonavir | Major | |
| Rifampin | Major | |
| Oral corticosteroids | Moderate | |
| Retinoids (topical) | Moderate |
🚨 Major Interactions
- Oral anticoagulants (e.g., warfarin)
- CYP3A4 inhibitors (e.g., ritonavir, clarithromycin)
- CYP3A4 inducers (e.g., rifampin, carbamazepine)
⚡ Moderate Interactions
- Corticosteroids (oral or topical)
- Other topical agents (e.g., retinoids, keratolytics)
🍷 Alcohol Interaction
No known interaction with alcohol when used topically. However, alcohol may worsen certain skin conditions. Consult your doctor.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Known hypersensitivity to beclometasone, ketoconazole, or any component of the formulation","Untreated bacterial or viral skin infections","Acne vulgaris, rosacea, perioral dermatitis","Use on broken skin or large areas","Children under 12 years (unless prescribed)"]
⚠️ Warnings & Precautions
["For external use only. Do not ingest.","Avoid contact with eyes, mouth, and mucous membranes.","Do not use on the face, groin, or underarms for more than 2 weeks unless directed.","Do not use for more than 4 weeks without medical advice.","Prolonged use may cause skin thinning, stretch marks, and adrenal suppression.","May mask signs of skin infection.","Consult a doctor if symptoms persist or worsen.","Keep out of reach of children."]
🤱 Lactation Safety
It is not known if beclometasone or ketoconazole pass into breast milk after topical application. However, systemic absorption is minimal. To be safe, avoid applying to the breast area and consult your doctor before use.
💊 Overdose Management
Topical overdose is unlikely. If accidental ingestion occurs, seek medical attention immediately. Symptoms of overdose may include nausea, vomiting, and abdominal pain. Treatment is supportive.
⏰ Missed Dose
If you miss a dose, apply it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not apply a double dose to make up for a missed one.
Additional Safety Advice
Apply this medicine only to the affected skin area as prescribed. Wash your hands before and after application. Avoid contact with eyes, mouth, and other mucous membranes. Do not cover the treated area with tight bandages or dressings unless instructed. Do not use on the face, groin, or underarms for more than 2 weeks unless directed by a doctor. Do not use for more than 4 weeks without medical advice. If you are pregnant, planning to become pregnant, or breastfeeding, consult your doctor before use. Keep out of reach of children. Do not share this medicine with others. If symptoms persist or worsen, consult your doctor.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients may be more susceptible to skin thinning and adrenal suppression with prolonged use. Use with caution and monitor for side effects.
🤰 Pregnancy Planning (TTC)
If you are planning pregnancy, consult your doctor before using this medicine. Topical corticosteroids and ketoconazole are generally considered low risk, but medical advice is recommended.
🏥 Post-Surgery Considerations
Consult your doctor before using this medicine on surgical wounds or broken skin. It should not be applied to open wounds unless specifically directed.
🦷 Dental Procedures
No specific considerations for dental procedures. However, inform your dentist if you are using this medicine.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
No specific exercise restrictions. However, if the infection is on the feet, avoid barefoot walking in public areas. Keep the affected area dry during exercise and change out of sweaty clothes promptly.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine is applied topically and is unlikely to affect your ability to drive or operate machinery. However, if you experience any dizziness or allergic reaction, avoid these activities until you feel better.
🛑 When to Stop This Medicine
Stop using this medicine and consult your doctor if you experience severe irritation, allergic reaction, or if symptoms worsen. Do not stop prematurely if symptoms improve; complete the full course as prescribed. If you have used it for 4 weeks without improvement, consult your doctor.
📅 Long-Term Use Effects
Prolonged use of this medicine, especially on large areas or under occlusive dressings, can lead to skin thinning, stretch marks, and adrenal suppression. It may also increase the risk of secondary infections. Use only as prescribed and for the recommended duration. Regular monitoring by a doctor is advised for extended use.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Good hygiene helps prevent fungal growth and supports healing.
Evidence: Well-establishedCan help keep skin folds dry and reduce moisture.
Evidence: ModerateHelps prevent athlete's foot and allows skin to breathe.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
No known interaction with vaccines. However, if you have a skin infection, consult your doctor before vaccination.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✅ DO
Keep out of reach of children
❌ DON'T
Do not use after expiry date
✈️ Traveling with This Medicine
Carry this medicine in its original packaging with the prescription label intact. Bring a copy of your prescription in case of customs checks. Store at room temperature, away from direct sunlight and moisture. If traveling to a hot climate, keep it in a cool, dry place. No time zone adjustments are needed for topical application. If you are flying, pack it in your carry-on or checked luggage as per airline regulations.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: Itching and redness may start to improve within a few days. The fungal infection typically clears within 2 to 4 weeks of regular use.
A: Avoid using on the face unless specifically directed by a doctor, as it can cause skin thinning and other side effects.
A: Consult your doctor before use. Topical corticosteroids and ketoconazole are generally considered low risk, but medical advice is recommended.
A: Apply it as soon as you remember. If it's almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double dose.
A: No, complete the full course as prescribed to ensure the infection is fully treated and to prevent recurrence.
🤔 Common Patient Concerns
🔄 Substitutes for ketonid-b cream
View AllAlternative brands with exact same active ingredient:
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can cure any skin rash.
Fact: It is only for fungal infections with inflammation. It can worsen bacterial or viral infections. - Myth: More cream means faster healing.
Fact: Apply only a thin layer. Using more does not speed up healing and may increase side effects. - Myth: It is safe to use indefinitely.
Fact: Prolonged use can cause skin thinning and other side effects. Use only as prescribed. - Myth: It can be used on the face freely.
Fact: Avoid using on the face unless specifically directed by a doctor, as it can cause skin thinning.
🔄 Alternative Options
Generic Alternatives
- Beclometasone + Ketoconazole cream (generic)