Diploderm Lite Cream: Complete Guide to Uses, Side Effects, and Safety
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Severe allergic reaction with swelling of face, lips, or throat, or difficulty breathing.
- Signs of systemic absorption such as fatigue, weight changes, or neck swelling (thyroid dysfunction).
- Neurological symptoms like numbness, tingling, or weakness.
- Severe skin irritation, blistering, or peeling that worsens.
- No improvement after 2-4 weeks of treatment.
- Fever or signs of spreading infection.
If experiencing severe symptoms, call emergency services immediately.
What is ketokey-k5 cream used for?
This medicine is a topical cream combining ketoconazole and clioquinol, used to treat fungal and bacterial skin infections. Apply a thin layer to the affected area once or twice daily as directed by your doctor.
- Generic Name: Ketoconazole (2% w/w) + Clioquinol (Iodochlorhydroxyquin) (1% w/w)
- Manufacturer: Biodiscovery Lifesciences Pvt Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 ketokey-k5 cream के बारे में (Hindi Summary)
उपयोग: यह दवा एक टॉपिकल क्रीम है जिसमें कीटोकोनाज़ोल और क्लियोक्विनोल होते हैं। यह फंगल और बैक्टीरियल त्वचा संक्रमणों के इलाज के लिए उपयोग की जाती है, जैसे दाद, खुजली, और एथलीट फुट। यह संक्रमण के कारण होने वाली खुजली, लालिमा और जलन को कम करने में मदद करती है।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में लगाने की जगह पर जलन, खुजली, लालिमा या सूखापन शामिल हो सकते हैं। ये आमतौर पर हल्के होते हैं और कुछ समय में ठीक हो जाते हैं। गंभीर दुष्प्रभाव दुर्लभ हैं, लेकिन अगर आपको गंभीर एलर्जी, सूजन, या सांस लेने में कठिनाई हो, तो तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: इस क्रीम को केवल बाहरी उपयोग के लिए ही लगाएं। आंखों, मुंह और अन्य श्लेष्मा झिल्ली के संपर्क में न आने दें। टूटी हुई त्वचा पर न लगाएं। डॉक्टर के बताए अनुसार ही उपयोग करें और बिना सलाह के लंबे समय तक न लगाएं। गर्भवती या स्तनपान कराने वाली महिलाएं डॉक्टर से सलाह लें।
💊 ketokey-k5 cream Uses & Benefits
[{"condition":"Tinea corporis (ringworm of the body)","description":"This medicine is effective in treating fungal infections of the skin caused by dermatophytes, helping to relieve itching, redness, and scaling.","evidence":"Well-established"},{"condition":"Tinea cruris (jock itch)","description":"It is used to treat fungal infections in the groin area, reducing discomfort and preventing spread.","evidence":"Well-established"},{"condition":"Tinea pedis (athlete's foot)","description":"This medicine helps eliminate fungal infections of the feet, including between the toes, and alleviates symptoms like itching and burning.","evidence":"Well-established"},{"condition":"Cutaneous candidiasis","description":"It is effective against yeast infections of the skin, such as those caused by Candida species, often in skin folds.","evidence":"Well-established"},{"condition":"Mixed bacterial and fungal skin infections","description":"The combination of ketoconazole and clioquinol targets both fungal and bacterial components of mixed skin infections.","evidence":"Moderate"}]
Off-label uses: [{"condition":"Seborrheic dermatitis","description":"Ketoconazole component may be effective, but the combination is not specifically approved for this condition.","evidence":"Limited"},{"condition":"Pityriasis versicolor","description":"Ketoconazole is effective, but the added clioquinol may not be necessary; used off-label.","evidence":"Limited"}]
Primary treatment for: Fungal skin infections
Also treats: Bacterial skin infections, Mixed skin infections
📋 Drug Information
| Generic Name(s) | Ketoconazole (2% w/w) + Clioquinol (Iodochlorhydroxyquin) (1% w/w) |
| Brand Name | ketokey-k5 cream |
| Manufacturer | Biodiscovery Lifesciences Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | DERMA |
| Action Class | |
| Route of Administration | Topical |
| Storage | Store below 25°C, protected from light and moisture. Do not freeze. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine combines two active ingredients with distinct mechanisms. Ketoconazole, an imidazole antifungal, inhibits the enzyme cytochrome P450 14α-demethylase, blocking the conversion of lanosterol to ergosterol, a vital component of fungal cell membranes. This leads to increased membrane permeability and leakage of cellular contents, ultimately causing fungal cell death. Clioquinol, a hydroxyquinoline derivative, exerts antibacterial and antiprotozoal effects by chelating metal ions essential for microbial metabolism and by disrupting DNA synthesis. It is particularly active against gram-positive bacteria and some gram-negative bacteria. Together, they provide broad-spectrum coverage against dermatophytes, yeasts, and certain bacteria.
Mechanism Steps
💡 How to Take ketokey-k5 cream
Strength: Cream containing Ketoconazole 2% w/w and Clioquinol 1% w/w.
Dosage Information
| Adult Dosage | Apply a thin layer of this medicine to the affected skin area and surrounding skin once or twice daily, or as directed by your doctor. The duration of treatment depends on the type and severity of the infection, typically 2 to 4 weeks. For tinea pedis, treatment may need to continue for 4 to 6 weeks to prevent recurrence. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | No specific dosage adjustments are required for elderly patients. However, elderly patients may be more susceptible to side effects. Use with caution and monitor for adverse reactions. |
| Renal Impairment | No dosage adjustment is required for renal impairment as systemic absorption is minimal. However, if used over large areas, consult a doctor. |
| Hepatic Impairment | No dosage adjustment is required for hepatic impairment as systemic absorption is minimal. However, if used over large areas, consult a doctor. |
| Maximum Daily Dose | Not established from the available information. Use only as directed by a doctor. |
Dosage Timeline
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of ketokey-k5 cream
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | |
| Sulfonylureas | Major | |
| Topical corticosteroids | Moderate | |
| Thyroid function tests | Moderate |
🚨 Major Interactions
- Oral anticoagulants (e.g., warfarin)
- Oral hypoglycemics
⚡ Moderate Interactions
- Other topical corticosteroids
- Thyroid function tests
🍷 Alcohol Interaction
No known interaction between this topical medicine and alcohol. However, alcohol may worsen certain skin conditions or interact with other medications you are taking.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Known hypersensitivity to ketoconazole, clioquinol, or any component of the formulation.","Application on broken skin, large areas, or under occlusive dressings.","Use in children under 2 years of age unless directed by a doctor.","Use for ophthalmic, oral, or intravaginal administration."]
⚠️ Warnings & Precautions
["For external use only. Avoid contact with eyes, nose, mouth, and other mucous membranes.","Do not use on large areas of the body or for prolonged periods without medical supervision.","If irritation or sensitization occurs, discontinue use and consult a doctor.","Clioquinol may cause thyroid dysfunction if absorbed systemically; avoid use on broken skin.","Use with caution in patients with liver disease or thyroid disorders.","Do not use if the tube is damaged or if the cream has changed color.","Keep out of reach of children."]
🤱 Lactation Safety
It is not known whether ketoconazole or clioquinol are excreted in human milk after topical application. Because many drugs are excreted in human milk, caution should be exercised when this medicine is used by a nursing woman. Avoid applying to the breast area to prevent infant exposure.
💊 Overdose Management
Overdose from topical application is unlikely. If accidental ingestion occurs, seek immediate medical attention. Symptoms of overdose may include nausea, vomiting, and abdominal pain. Treatment is symptomatic and supportive.
⏰ Missed Dose
If you miss a dose, apply it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not apply a double dose to make up for a missed one.
Additional Safety Advice
For external use only. Avoid contact with eyes, mouth, and other mucous membranes. If accidental contact occurs, rinse thoroughly with water. Do not apply to large areas of the body or under occlusive dressings unless directed by a doctor. Do not use for longer than prescribed. Wash your hands before and after applying the cream. Keep out of reach of children. Do not use if the tube is damaged or if the cream has changed color. Inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding. Avoid using other topical products on the same area without medical advice. If symptoms do not improve after 2-4 weeks, consult your doctor.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients may be more susceptible to side effects. Use with caution and monitor for any adverse reactions. No specific dosage adjustments are required.
🤰 Pregnancy Planning (TTC)
Consult your doctor before using this medicine if you are planning to become pregnant or are pregnant. The safety of this medicine during pregnancy has not been fully established.
🏥 Post-Surgery Considerations
Consult your doctor before using this medicine on surgical wounds or broken skin. It should not be applied to open wounds.
🦷 Dental Procedures
No specific considerations for dental procedures. However, inform your dentist about all medications you are using.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
No specific exercise restrictions are required while using this medicine. However, if the infection is on the feet, avoid walking barefoot in public areas to prevent spread.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine is applied topically and is unlikely to affect your ability to drive or operate machinery. However, if you experience any allergic reaction or irritation, avoid these activities until you feel better.
🛑 When to Stop This Medicine
Stop using this medicine and consult your doctor if your symptoms do not improve after 2-4 weeks, if they worsen, or if you experience severe side effects. Do not stop abruptly without consulting your doctor if you have been using it for a prolonged period.
📅 Long-Term Use Effects
Prolonged use over large areas may increase the risk of systemic absorption, leading to potential thyroid dysfunction or neurotoxicity due to clioquinol. Therefore, use should be limited to the prescribed duration and area. Regular monitoring may be required if extended use is necessary.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Keeping the skin clean and dry can help prevent fungal infections.
Evidence: Well-establishedAlternative antifungal creams may be used for fungal infections.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
No known interactions with vaccines. However, consult your doctor before receiving any vaccine while using this medicine.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
Carry this medicine in its original packaging with a copy of your prescription. Store it in a cool, dry place away from direct sunlight. If traveling to a different time zone, continue your regular application schedule. Check customs regulations for carrying medications across borders. Keep it in your carry-on luggage if flying.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: You may start noticing improvement in symptoms like itching and redness within a few days. However, complete resolution may take 2 to 4 weeks, depending on the type and severity of the infection.
A: It is generally not recommended for use on the face unless specifically prescribed by your doctor. The skin on the face is sensitive and may be more prone to irritation.
A: No, this cream does not contain steroids. It contains ketoconazole, an antifungal, and clioquinol, an antibacterial agent.
A: If you miss a dose, apply it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not apply a double dose.
🤔 Common Patient Concerns
🔄 Substitutes for ketokey-k5 cream
View AllAlternative brands with exact same active ingredient:
-
dermozeel creamPilco Pharma Pvt Ltd ₹59.06 16% CHEAPER
-
diploderm lite creamKaymed Pharmaceuticals Pvt. Ltd. ₹60.84 13.5% CHEAPER
-
dermicraft 5 creamCure Tech Skincare ₹60.94 13.3% CHEAPER
-
dermiwin kt 5 creamWindlas Biotech Ltd ₹64.69 8% CHEAPER
-
corci kt creamAjanta Pharma Ltd ₹70.31 SAME PRICE
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This cream can be used for any skin rash.
Fact: It is specifically for fungal and bacterial infections. Using it for other rashes may worsen the condition. - Myth: You can stop using it as soon as symptoms improve.
Fact: Complete the full course as prescribed to prevent recurrence. - Myth: More cream means faster healing.
Fact: Apply only a thin layer. Using more does not speed up healing and may increase side effects.
🔄 Alternative Options
Generic Alternatives
- Ketoconazole 2% + Clioquinol 1% cream