kayatic ac ear drop - Gentamicin (0.3% w/v) + Clotrimazole (1% w/v) medicine

Antikind Ear Drop: Comprehensive Guide to Uses, Side Effects, and Safety

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🏭 Kenrox Healthcare Pvt. Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Sep 23, 2026
📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Well-established for otitis externa and otomycosis.
Reviewed by
SaathiMed Expert Panel | Sep 23, 2026

When to Call Your Doctor IMMEDIATELY

  • Sudden hearing loss or ringing in the ears
  • Severe dizziness or balance problems
  • Swelling of the face, lips, or throat
  • Difficulty breathing
  • Severe pain or discharge from the ear
  • Fever with ear pain
  • Redness or swelling spreading beyond the ear

If experiencing severe symptoms, call emergency services immediately.

What is kayatic ac ear drop used for?

This medicine is a combination ear drop containing gentamicin (an antibiotic) and clotrimazole (an antifungal). It is used to treat ear infections caused by bacteria and fungi. It works by killing the microorganisms and reducing inflammation. Use it only in the ear as prescribed by your doctor.

  • Generic Name: Gentamicin (0.3% w/v) + Clotrimazole (1% w/v)
  • Manufacturer: Kenrox Healthcare Pvt. Ltd
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 kayatic ac ear drop के बारे में (Hindi Summary)

उपयोग: यह दवा एक संयोजन कान की बूंद है जिसमें जेंटामाइसिन (एक एंटीबायोटिक) और क्लोट्रिमाज़ोल (एक एंटीफंगल) शामिल हैं। इसका उपयोग कान के संक्रमण के इलाज के लिए किया जाता है जो बैक्टीरिया और फंगस के कारण होते हैं। यह कान के बाहरी हिस्से में सूजन, खुजली और दर्द को कम करने में मदद करता है। इस दवा का उपयोग केवल कान में ही करें, मुंह से न लें।

साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में कान में हल्की जलन, खुजली या लालिमा शामिल हो सकती है। गंभीर दुष्प्रभाव दुर्लभ हैं लेकिन इनमें सुनने में कमी, चक्कर आना, या गंभीर एलर्जी प्रतिक्रिया शामिल हो सकती है। यदि आपको कोई असामान्य लक्षण दिखे तो तुरंत डॉक्टर से संपर्क करें।

सुरक्षा सलाह: इस दवा का उपयोग करने से पहले अपने डॉक्टर को अपनी सभी एलर्जी और दवाओं के बारे में बताएं। यदि आपके कान का पर्दा फटा हुआ है तो इस दवा का उपयोग न करें। उपयोग से पहले और बाद में हाथ धोएं। बूंदें डालने के बाद 2-3 मिनट तक करवट लेटे रहें। निर्धारित अवधि तक दवा का पूरा कोर्स करें।

💡 Did You Know? Over 80% of the antiretroviral drugs used globally to combat AIDS are supplied by Indian pharmaceutical companies.

💊 kayatic ac ear drop Uses & Benefits

[{"condition":"Otitis externa (swimmer's ear)","description":"This medicine is used to treat bacterial and fungal infections of the outer ear canal, reducing inflammation, itching, and pain.","evidence":"Well-established"},{"condition":"Fungal ear infection (otomycosis)","description":"The clotrimazole component targets fungi such as Candida and Aspergillus, while gentamicin covers secondary bacterial infections.","evidence":"Well-established"},{"condition":"Chronic suppurative otitis media","description":"May be used in some cases when the eardrum is intact, but only under strict medical supervision due to risk of inner ear damage.","evidence":"Limited"}]

Off-label uses: [{"condition":"Prevention of infection after ear surgery","description":"Sometimes prescribed off-label to prevent bacterial and fungal infections following certain ear procedures, but only if the eardrum is intact.","evidence":"Limited"}]

Primary treatment for: Otitis externa

Also treats: Otomycosis, Chronic suppurative otitis media

📋 Drug Information

Generic Name(s)Gentamicin (0.3% w/v) + Clotrimazole (1% w/v)
Brand Namekayatic ac ear drop
ManufacturerKenrox Healthcare Pvt. Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassOTOLOGICALS
Action Class
Route of AdministrationOtic (into the ear canal)
StorageStore at room temperature between 15°C and 30°C (59°F to 86°F). Protect from light and moisture. Keep the bottle tightly closed when not in use.
Shelf Life24 months from the date of manufacture, or as indicated on the packaging.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Always warm the ear drops by holding the bottle in your hands for a few minutes before use to prevent dizziness.
2
Do not touch the dropper tip to your ear or any other surface to avoid contamination.
3
Use the medicine for the full prescribed duration, even if symptoms improve, to prevent recurrence.
4
If you have a perforated eardrum, do not use this medicine unless specifically directed by your doctor.
5
Avoid getting water in your ear during treatment to prevent worsening of the infection.
6
If symptoms do not improve within 7 days, consult your doctor for further evaluation.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

Ear pain
This medicine is commonly prescribed for ear pain due to bacterial or fungal infection.
Likely Use
Itching in the ear
This medicine can help relieve itching caused by fungal infections.
Likely Use
Fever
This medicine is not a primary fever reducer. Consult a doctor if fever is present.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionGentamicin and clotrimazole are minimally absorbed into the bloodstream when applied topically to the ear canal, provided the eardrum is intact. Systemic absorption is negligible under normal conditions.
DistributionSince systemic absorption is minimal, distribution into body tissues is not significant. The medicine acts locally in the ear canal.
Protein BindingNot established from the available information.
MetabolismNot established from the available information for topical otic use. Any small amount absorbed may be metabolized in the liver, but this is not clinically relevant.
Half-LifeNot established from the available information for topical otic use.
ExcretionNot established from the available information for topical otic use.
BioavailabilityNot established from the available information for topical otic use.
Onset of ActionSymptom relief may begin within a few days of starting treatment, but complete resolution of infection typically takes 7 to 10 days.
Peak Plasma TimeNot established from the available information.
Duration of ActionThe local effect lasts between doses, and the medicine should be used for the full prescribed duration, usually 7 to 10 days.

How It Works

This medicine combines two active ingredients with distinct mechanisms. Gentamicin is an aminoglycoside antibiotic that binds irreversibly to the 30S ribosomal subunit of susceptible bacteria, inhibiting protein synthesis and leading to bacterial cell death. Clotrimazole is an imidazole antifungal that inhibits the synthesis of ergosterol, a key component of fungal cell membranes, causing increased membrane permeability and leakage of cellular contents, which results in fungal cell death. Together, they provide broad-spectrum coverage against both bacteria and fungi commonly found in ear infections.

Mechanism Steps

1
Gentamicin binding to bacterial ribosome: Gentamicin binds to the 30S ribosomal subunit of bacteria, causing misreading of mRNA and inhibiting protein synthesis.
2
Bacterial cell death: The disruption of protein synthesis leads to the production of faulty proteins and ultimately bacterial cell death.
3
Clotrimazole inhibition of ergosterol synthesis: Clotrimazole inhibits the fungal enzyme 14α-demethylase, blocking the conversion of lanosterol to ergosterol.
4
Fungal cell membrane damage: Without ergosterol, the fungal cell membrane becomes permeable, leading to leakage of essential cellular components and cell death.

💡 How to Take kayatic ac ear drop

Strength: Ear drops containing gentamicin 0.3% w/v and clotrimazole 1% w/v.

1Wash your hands thoroughly with soap and water.
2Warm the ear drop bottle by holding it in your hands for a few minutes.
3Lie on your side with the affected ear facing up.
4Gently pull the earlobe upward and backward to straighten the ear canal.
5Instill the prescribed number of drops into the ear canal.
6Stay in this position for 2-3 minutes to allow the medicine to reach the infection.
7Replace the cap on the bottle and wash your hands again.
8Repeat for the other ear if directed by your doctor.

Dosage Information

Adult DosageThe usual adult dose is 2 to 3 drops instilled into the affected ear canal 2 to 3 times daily, or as directed by your doctor. The frequency and duration depend on the severity of the infection and your response to treatment. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Use for the full prescribed duration, even if symptoms improve.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician for appropriate dosing in children.
Elderly DosageElderly patients may use this medicine at the same dose as adults, but they should be monitored more closely for signs of hearing changes or dizziness. Dose must be individualized by a qualified clinician.
Renal ImpairmentNo dosage adjustment is typically required for topical otic use, as systemic absorption is minimal. However, if the eardrum is perforated, consult your doctor as dose adjustment may be needed.
Hepatic ImpairmentNo dosage adjustment is typically required for topical otic use, as systemic absorption is minimal.
Maximum Daily DoseThe maximum daily dose is not established from the available information. Use only as prescribed by your doctor.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

No food restrictions
No specific timing
This medicine is applied topically in the ear and is not affected by food.

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Apply the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of kayatic ac ear drop

✅ Common Side Effects

Ear irritation or burning (Common (5-10%))
This usually resolves on its own. If it persists or worsens, consult your doctor.
Itching in the ear (Common (5-10%))
Avoid scratching the ear. If itching is severe, contact your doctor.
Redness or swelling at application site (Uncommon (1-5%))
Stop using the medicine and consult your doctor if redness or swelling occurs.

🚨 Serious Side Effects

Hearing loss or ringing in the ears (Rare (<0.1%))
Stop using this medicine immediately and seek medical attention if you notice any change in hearing.
Severe allergic reaction (anaphylaxis) (Rare (<0.1%))
Seek emergency medical help if you experience swelling of the face, lips, throat, or difficulty breathing.
Dizziness or balance problems (Rare (<0.1%))
Stop using the medicine and contact your doctor if you feel dizzy or unsteady.

⚠️ Rare Side Effects

Secondary fungal or bacterial infection
Consult your doctor if you notice new or worsening symptoms.
Skin peeling or severe irritation
Discontinue use and seek medical advice.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Other aminoglycosides Major
Loop diuretics Major
Other ear drops Moderate

🚨 Major Interactions

  • Other aminoglycosides (e.g., neomycin, streptomycin)
  • Loop diuretics (e.g., furosemide)

⚡ Moderate Interactions

  • Other ear drops

🍷 Alcohol Interaction

No known interaction between this medicine and alcohol when used as directed in the ear. However, alcohol may worsen dizziness if you are experiencing balance issues from an ear infection.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Allergy to gentamicin, clotrimazole, or any component of the formulation.","Perforated eardrum or history of ear surgery, unless directed by a doctor.","Viral or fungal infections not susceptible to the components.","Use in the eye or other body areas."]

⚠️ Warnings & Precautions

["For otic use only. Do not take by mouth.","Do not use if the eardrum is perforated, as it may cause hearing loss.","Avoid touching the dropper tip to any surface to prevent contamination.","Prolonged use may lead to overgrowth of non-susceptible organisms.","Consult a doctor if symptoms do not improve within 7 days.","Keep out of reach of children.","Do not use after the expiry date."]

🤱 Lactation Safety

It is not known whether gentamicin or clotrimazole pass into breast milk when used as ear drops. However, systemic absorption is minimal. Consult your doctor before using this medicine while breastfeeding.

💊 Overdose Management

Overdose with this medicine is unlikely due to its topical route. If excessive amounts are applied or accidentally ingested, seek medical attention immediately. Symptoms of overdose may include nausea, vomiting, or dizziness if ingested.

⏰ Missed Dose

If you miss a dose, apply it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up.

Additional Safety Advice

General Safety

Before using this medicine, inform your doctor if you are allergic to gentamicin, clotrimazole, or any other medications. Do not use this medicine if you have a perforated eardrum or a history of ear surgery, unless specifically directed by your doctor. Wash your hands thoroughly before and after applying the drops. Warm the bottle in your hands for a few minutes to avoid dizziness from cold drops. Lie on your side with the affected ear facing up, gently pull the earlobe to open the ear canal, and instill the prescribed number of drops. Stay in this position for 2-3 minutes to let the medicine reach the infection. Do not touch the dropper tip to your ear or any surface to avoid contamination. Use this medicine for the full prescribed duration, even if symptoms improve, to prevent recurrence. Avoid getting water in your ear during treatment. If symptoms do not improve within a few days or worsen, contact your doctor.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients may be more susceptible to the effects of gentamicin, especially if the eardrum is perforated. Close monitoring for hearing changes and balance problems is recommended.

🤰 Pregnancy Planning (TTC)

If you are planning to become pregnant, consult your doctor before using this medicine. It is generally considered safe for topical use, but medical advice is recommended.

🏥 Post-Surgery Considerations

If you have had ear surgery, do not use this medicine unless specifically directed by your surgeon, as it may interfere with healing or cause complications.

🦷 Dental Procedures

No specific considerations for dental procedures. However, inform your dentist about all medications you are using.

💚 Lifestyle Tips for Better Results

🏃
Keep your ears dry and clean.
🥗
Avoid inserting cotton swabs or other objects into the ear canal.
😴
Use earplugs when swimming to prevent water from entering the ear.
💧
Treat underlying conditions like allergies or eczema that may contribute to ear infections.
🧘
Follow good hygiene practices, especially after swimming or bathing.

🏋️ Exercise Considerations

Avoid swimming or water sports until the infection has completely resolved. Other exercises are generally safe, but if you experience dizziness, avoid activities that require balance.

🥗 Diet Recommendations

Stay well hydrated.
Include foods rich in vitamin C and zinc to support immune function.
Avoid excessive sugar intake, which may promote fungal growth.
Eat a balanced diet to support overall health.

💼 Impact on Daily Work & Life

This medicine is unlikely to affect your ability to work or drive. However, if you experience dizziness or balance problems, avoid driving or operating heavy machinery until you feel normal.

🛑 When to Stop This Medicine

Stop using this medicine if you experience any signs of an allergic reaction, hearing loss, or worsening of symptoms. Do not stop prematurely unless instructed by your doctor, as this may lead to recurrence of the infection.

📅 Long-Term Use Effects

Long-term use of this medicine is not recommended unless directed by a doctor. Prolonged use can lead to overgrowth of non-susceptible organisms and, if the eardrum is perforated, may increase the risk of hearing loss. Regular monitoring of hearing function is advised if extended use is necessary.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Keep ears dry

Preventing water from entering the ear can help prevent swimmer's ear.

Evidence: Well-established
Avoid irritants

Avoid inserting foreign objects into the ear and use gentle cleaning methods.

Evidence: Well-established

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

No specific vaccination considerations are associated with this medicine. However, keeping vaccinations up to date, such as pneumococcal and influenza vaccines, can help prevent some ear infections.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

When traveling with this medicine, carry it in its original packaging along with a copy of your prescription. Store it at room temperature and protect it from extreme heat or cold. If you are crossing time zones, continue with your regular dosing schedule as prescribed. Keep the bottle upright to prevent leakage. Check customs regulations for carrying prescription medications.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 35-year-old swimmer with recurrent ear infections
This patient had been suffering from itchy, painful ears after swimming. The doctor prescribed this medicine. After using it for 3 days, the itching reduced significantly. The patient completed the 7-day course and has not had an infection since.
💡 Lesson: Completing the full course of treatment is essential to prevent recurrence, even if symptoms improve.
👤 A 50-year-old with diabetes and a fungal ear infection
This patient developed a fungal ear infection that was not responding to other drops. The doctor prescribed this medicine. The patient used it for 10 days and noticed gradual improvement. The doctor monitored hearing throughout treatment.
💡 Lesson: For fungal infections, it is important to use the medicine for the full duration and monitor for any hearing changes.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: You may start feeling relief within 2-3 days, but complete resolution of the infection usually takes 7-10 days.

Q: Can I use this medicine if I have a perforated eardrum?

A: No, you should not use this medicine if you have a perforated eardrum unless specifically directed by your doctor, as it can cause hearing loss.

Q: Is this medicine safe for children?

A: Pediatric dosing is not established. Consult a pediatrician for appropriate use in children.

Q: Can I use this medicine during pregnancy?

A: Consult your doctor before using this medicine during pregnancy. It is generally considered low risk when used topically, but medical advice is necessary.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I use this medicine for my child?
  • What if I accidentally swallow this medicine?
  • Can I use this medicine if I have a cold?
  • Does this medicine affect my hearing?
  • Can I use this medicine with other ear drops?
  • How long does it take to work?

🔄 Substitutes for kayatic ac ear drop

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: This medicine can be used for any ear pain.
    Fact: This medicine is only for bacterial and fungal ear infections. It is not effective for viral infections or ear pain due to other causes.
  • Myth: You can stop using this medicine as soon as symptoms improve.
    Fact: You must complete the full prescribed course to prevent the infection from returning.
  • Myth: This medicine is safe to use if you have a perforated eardrum.
    Fact: No, using this medicine with a perforated eardrum can cause hearing loss. Consult your doctor first.

🔄 Alternative Options

Generic Alternatives

  • Gentamicin 0.3% w/v + Clotrimazole 1% w/v ear drops

Brand Alternatives

  • Antikind ear drop

📊 Comparison with Similar Medicines

[{"medicine":"This medicine","composition":"Gentamicin + Clotrimazole","uses":"Bacterial and fungal ear infections","route":"Otic"},{"medicine":"Ciprofloxacin ear drops","composition":"Ciprofloxacin","uses":"Bacterial ear infections","route":"Otic"},{"medicine":"Clotrimazole ear drops","composition":"Clotrimazole","uses":"Fungal ear infections","route":"Otic"}]

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