k druf 100 ml lotion - Ketoconazole (2% w/w) + Zinc pyrithione (1% w/w) medicine

Beetoc Shampoo: Complete Guide to Uses, Dosage, and Safety

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🏭 Nostrum Pharmaceuticals 📦 Varies by brand 💊 Allopathy 📅 Updated: Sep 26, 2026
🤰 Pregnancy Category Not established from the available information. Topical ketoconazole and zinc pyrithione are generally considered low risk when used as directed, but consult your doctor before use. 📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Well-established for dandruff and seborrheic dermatitis; moderate for tinea versicolor.
Reviewed by
SaathiMed Expert Panel | Sep 26, 2026
🩺
Medically Fact-Checked & Clinically Verified by SaathiMed Clinical Review Board
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026

When to Call Your Doctor IMMEDIATELY

  • Swelling of the face, lips, tongue, or throat
  • Difficulty breathing or swallowing
  • Severe redness, blistering, or peeling of the scalp
  • Intense burning or pain at the application site
  • Signs of infection such as pus, fever, or swollen lymph nodes
  • Sudden hair loss or severe breakage
  • No improvement after 4 weeks of regular use

If experiencing severe symptoms, call emergency services immediately.

What is k druf 100 ml lotion used for?

This medicine is a medicated shampoo containing ketoconazole 2% and zinc pyrithione 1%. It treats dandruff and seborrheic dermatitis by reducing Malassezia yeast on the scalp. Apply to wet scalp, lather, leave for 3-5 minutes, and rinse. Use twice weekly for 2-4 weeks, then as directed.

  • Generic Name: Ketoconazole (2% w/w) + Zinc pyrithione (1% w/w)
  • Manufacturer: Nostrum Pharmaceuticals
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 k druf 100 ml lotion के बारे में (Hindi Summary)

उपयोग: यह दवा एक मेडिकेटेड शैम्पू है जिसमें कीटोकोनाज़ोल 2% और जिंक पाइरिथियोन 1% शामिल हैं। यह डैंड्रफ (रूसी), स्कैल्प की सूजन, खुजली और सेबोरहिक डर्मेटाइटिस के इलाज के लिए इस्तेमाल की जाती है। यह स्कैल्प पर फंगस के बढ़ने को रोककर रूसी और खुजली को कम करती है। इसे गीले बालों पर लगाएं, 3-5 मिनट तक छोड़ें और फिर धो लें। आमतौर पर इसे हफ्ते में दो बार 2-4 हफ्तों तक इस्तेमाल किया जाता है, फिर डॉक्टर की सलाह के अनुसार।

साइड इफेक्ट्स: आम दुष्प्रभावों में स्कैल्प में हल्की जलन, सूखापन, खुजली और बालों की बनावट में अस्थायी बदलाव शामिल हैं। कभी-कभी लालिमा या जलन हो सकती है। गंभीर एलर्जी प्रतिक्रिया दुर्लभ है, लेकिन अगर चेहरे, होंठ या गले में सूजन, सांस लेने में कठिनाई हो तो तुरंत डॉक्टर से मिलें।

सुरक्षा सलाह: इस दवा का इस्तेमाल केवल बाहरी रूप से करें। आंखों, नाक, मुंह और अन्य श्लेष्मा झिल्ली के संपर्क में न आने दें। अगर संपर्क हो जाए तो तुरंत पानी से धो लें। घाव या बहुत ज्यादा सूजी हुई त्वचा पर न लगाएं। बच्चों की पहुंच से दूर रखें। गर्भवती या स्तनपान कराने वाली महिलाएं डॉक्टर की सलाह के बिना इस्तेमाल न करें।

💡 Did You Know? India is the largest provider of generic medicines globally, supplying over 50% of global vaccine demand.

💊 k druf 100 ml lotion Uses & Benefits

[{"condition":"Dandruff","description":"Reduces flaking, itching, and scaling of the scalp by controlling Malassezia yeast overgrowth.","evidence":"Well-established"},{"condition":"Seborrheic dermatitis of the scalp","description":"Helps control redness, greasy scales, and irritation associated with seborrheic dermatitis.","evidence":"Well-established"},{"condition":"Tinea versicolor","description":"Used as an adjunctive treatment for this fungal skin infection when applied to affected areas as directed.","evidence":"Moderate"}]

Off-label uses: [{"condition":"Seborrheic dermatitis of the face or body","description":"Sometimes recommended by dermatologists for short-term use on affected areas other than the scalp.","evidence":"Limited"}]

Primary treatment for: Dandruff and seborrheic dermatitis of the scalp

Also treats: Tinea versicolor, Seborrheic dermatitis of other areas (off-label)

📋 Drug Information

Generic Name(s)Ketoconazole (2% w/w) + Zinc pyrithione (1% w/w)
Brand Namek druf 100 ml lotion
ManufacturerNostrum Pharmaceuticals
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassDERMA
Action Class
Route of AdministrationTopical
StorageStore at room temperature (15-30°C) in a dry place, away from direct sunlight and moisture. Keep the container tightly closed.
Shelf Life24 months from the date of manufacture or as printed on the pack.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Apply this medicine to a wet scalp and leave it on for at least 3 to 5 minutes before rinsing for best results.
2
Use it twice weekly for the first 2 to 4 weeks, then reduce to once weekly or as advised by your doctor.
3
Avoid getting the shampoo in your eyes; if it happens, rinse thoroughly with cool water.
4
Do not use more than the recommended frequency, as it may irritate the scalp.
5
If your dandruff does not improve after 4 weeks of regular use, consult a dermatologist.
6
Use a gentle, non-medicated conditioner after shampooing if your hair feels dry.
7
Keep the shampoo in its original container and store it away from direct sunlight.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅
Dandruff
This medicine is commonly prescribed for this.
Likely Use
✅
Scalp itching
This medicine helps relieve itching associated with dandruff and seborrheic dermatitis.
Likely Use
✅
Greasy yellow scales on scalp
This medicine is indicated for seborrheic dermatitis.
Likely Use
❌
Fever
This medicine is not a fever reducer.
Not Primary
❌
Body ache
This medicine is not for internal use and does not treat body aches.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionSystemic absorption of ketoconazole and zinc pyrithione after topical application to intact scalp is minimal. Not established from the available information for this specific formulation.
DistributionNot established from the available information.
Protein BindingNot established from the available information.
MetabolismNot established from the available information.
Half-LifeNot established from the available information.
ExcretionNot established from the available information.
BioavailabilityNot established from the available information.
Onset of ActionImprovement in itching and flaking may begin within a few days, but visible reduction in scaling typically takes 2 to 4 weeks of regular use.
Peak Plasma TimeNot established from the available information.
Duration of ActionThe effect on the scalp persists between applications; regular use is needed to maintain control of symptoms.

How It Works

Ketoconazole inhibits the fungal enzyme cytochrome P450 14α-demethylase, blocking the conversion of lanosterol to ergosterol, which is essential for fungal cell membrane integrity. This leads to increased membrane permeability and fungal cell death. Zinc pyrithione disrupts fungal cell membrane transport and inhibits fungal growth, and it also has antibacterial properties against certain organisms. The combination provides broad-spectrum antifungal and antimicrobial action on the scalp.

Mechanism Steps

1
Binding to fungal enzyme: Ketoconazole binds to and inhibits cytochrome P450 14α-demethylase in susceptible fungi.
2
Ergosterol synthesis blockade: This inhibition prevents the synthesis of ergosterol, a key component of the fungal cell membrane.
3
Membrane disruption: Without ergosterol, the fungal cell membrane becomes permeable and leaks essential cellular contents.
4
Zinc pyrithione action: Zinc pyrithione further disrupts fungal membrane transport and inhibits growth, complementing ketoconazole.
5
Reduced fungal load: The combined action lowers Malassezia numbers on the scalp, reducing dandruff and inflammation.

💡 How to Take k druf 100 ml lotion

Strength: Shampoo containing Ketoconazole 2% w/w and Zinc pyrithione 1% w/w.

1Wet your hair and scalp thoroughly with water.
2Apply a sufficient amount of this medicine to the scalp and hair.
3Gently massage into the scalp to form a lather.
4Leave the lather on for 3 to 5 minutes.
5Rinse thoroughly with water until no residue remains.
6Use as often as directed by your doctor, usually twice weekly for initial treatment.

Dosage Information

Adult DosageFor dandruff and seborrheic dermatitis: Apply to wet scalp, lather, and leave on for 3 to 5 minutes, then rinse thoroughly. Use twice weekly for 2 to 4 weeks, then once weekly or as directed by a clinician. For tinea versicolor: Apply to affected areas as directed by a doctor. Dose must be individualized by a qualified clinician based on indication, age, and response to treatment.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageNo specific dose adjustment is required for elderly patients when used topically as directed. However, consult a doctor if you have underlying medical conditions.
Renal ImpairmentNo dose adjustment is expected for topical use because systemic absorption is minimal. Consult a doctor if you have severe kidney disease.
Hepatic ImpairmentNo dose adjustment is expected for topical use because systemic absorption is minimal. Consult a doctor if you have severe liver disease.
Maximum Daily DoseNot applicable for topical use. Use as directed by a clinician; do not exceed the recommended frequency.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Use the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not double the amount to catch up.

⚠️ Side Effects of k druf 100 ml lotion

✅ Common Side Effects

Scalp irritation (Common (5-10%))
Usually resolves on its own. If it persists, reduce frequency or consult a doctor.
Scalp dryness (Common (5-10%))
Use a gentle conditioner after shampooing. Consult a doctor if severe.
Itching (Common (5-10%))
Avoid scratching. If itching worsens, stop use and consult a doctor.
Hair texture change (Uncommon (1-5%))
This is usually temporary. Use a moisturizing conditioner if needed.

🚨 Serious Side Effects

Severe allergic reaction (anaphylaxis) (Rare (<0.1%))
Seek immediate medical attention if you experience swelling of face, lips, throat, or difficulty breathing.
Severe skin reaction (contact dermatitis) (Rare (<0.1%))
Stop use and consult a doctor if you develop severe redness, blistering, or peeling.

⚠️ Rare Side Effects

Hair loss
Consult a doctor if you notice unusual hair loss while using this medicine.
Skin discoloration
Usually reversible. Consult a doctor if concerned.

Consult your doctor if you experience any unusual symptoms.

🛡️ Safety & Warnings

🚫 Contraindications

["Known hypersensitivity to ketoconazole, zinc pyrithione, or any component of the formulation","Application on broken or severely inflamed skin","Use in children under 12 years without medical advice"]

⚠️ Warnings & Precautions

["For external use only. Do not swallow.","Avoid contact with eyes. If contact occurs, rinse thoroughly with water.","Do not use on open wounds or infected skin.","Consult a doctor if condition worsens or does not improve after 4 weeks of regular use.","Keep out of reach of children.","Do not use if you are pregnant or breastfeeding without consulting a doctor."]

🤱 Lactation Safety

It is not known whether ketoconazole or zinc pyrithione pass into breast milk after topical application. Consult your doctor before use if breastfeeding. Avoid applying to the breast area to prevent infant exposure.

💊 Overdose Management

Accidental ingestion may cause nausea, vomiting, or abdominal discomfort. Seek medical attention if swallowed. Topical overdose is unlikely; if excessive application occurs, rinse the area with water and consult a doctor if irritation develops.

⏰ Missed Dose

If you miss a scheduled application, use it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the amount to catch up.

Additional Safety Advice

General Safety

For external use only. Avoid contact with eyes, nose, mouth, and other mucous membranes. If accidental contact occurs, rinse thoroughly with water. Do not use on open wounds, cuts, or severely inflamed skin. Do not cover the treated area with airtight dressings unless directed. Keep out of reach of children. Do not use for longer than prescribed without medical advice. If you are pregnant, planning pregnancy, or breastfeeding, consult your doctor before use. Do not share this medicine with others. Store at room temperature away from direct sunlight and moisture.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients can use this medicine as directed. However, they may have more sensitive skin, so monitor for irritation. Consult a doctor if you have underlying medical conditions.

🤰 Pregnancy Planning (TTC)

If you are planning pregnancy, consult your doctor before using this medicine. Topical ketoconazole and zinc pyrithione are generally considered low risk, but individual advice is recommended.

🏥 Post-Surgery Considerations

No specific restrictions after surgery. However, avoid applying to surgical wounds or broken skin. Consult your doctor if you have concerns.

🦷 Dental Procedures

No specific considerations for dental procedures. Continue your regular use unless advised otherwise by your doctor.

💚 Lifestyle Tips for Better Results

🏃
Wash your hair regularly with a gentle shampoo to remove excess oil and flakes.
🥗
Avoid scratching your scalp, as it can worsen irritation and lead to infection.
😴
Manage stress through relaxation techniques, as stress can trigger dandruff flare-ups.
💧
Eat a balanced diet rich in vitamins and minerals to support scalp health.
🧘
Avoid sharing combs, brushes, or hats to prevent the spread of fungal infections.
🌞
Limit the use of harsh hair styling products that can irritate the scalp.

🏋️ Exercise Considerations

No specific exercise restrictions are needed while using this medicine. However, if you experience scalp irritation, avoid activities that cause excessive sweating until it resolves.

🥗 Diet Recommendations

Include foods rich in zinc, such as nuts, seeds, and whole grains.
Eat plenty of fruits and vegetables for antioxidant support.
Stay well hydrated to maintain healthy skin and scalp.
Limit sugary and processed foods, which may worsen inflammation.

💼 Impact on Daily Work & Life

This medicine has no effect on your ability to drive or operate machinery. It may cause mild scalp irritation, but this does not usually interfere with daily activities.

🛑 When to Stop This Medicine

Stop using this medicine and consult a doctor if you experience severe irritation, allergic reactions, or if your condition does not improve after 4 weeks of regular use. Do not stop prescribed treatment without consulting your doctor.

📅 Long-Term Use Effects

Long-term use of this medicine is generally well tolerated. However, prolonged use may lead to scalp dryness, irritation, or temporary hair texture changes. Regular monitoring by a doctor is advised if used for extended periods. If you experience persistent irritation or no improvement, consult a dermatologist.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Selenium sulfide shampoo

Another medicated shampoo that can help control dandruff.

Evidence: Well-established
Ciclopirox olamine shampoo

An antifungal shampoo used for dandruff and seborrheic dermatitis.

Evidence: Well-established
Coal tar shampoo

Helps reduce scaling and itching, but may have a strong odor and stain.

Evidence: Moderate

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

No known interaction between this medicine and vaccines. Continue your regular vaccination schedule as advised by your doctor.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

Carry this medicine in its original packaging with a copy of your prescription. Store it in a cool, dry place away from direct sunlight. If traveling to a different time zone, continue your regular schedule; no time adjustment is needed for topical use. Declare it at customs if required. Keep it in your carry-on luggage if you need it during the journey.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 32-year-old woman with persistent dandruff and scalp itching
She had tried several over-the-counter anti-dandruff shampoos without lasting relief. Her dermatologist recommended this medicine twice weekly. After 3 weeks, her flaking and itching reduced significantly. She now uses it once weekly for maintenance and follows a gentle hair care routine.
💡 Lesson: Consistent use as directed and following up with maintenance therapy can provide long-term control of dandruff.
👤 A 45-year-old man with seborrheic dermatitis of the scalp
He experienced greasy yellow scales and redness along the hairline. He was prescribed this medicine to use twice weekly. He noticed improvement in scaling and irritation within 2 weeks. He was advised to avoid scratching and to use a mild moisturizing conditioner.
💡 Lesson: Combining medicated shampoo with gentle scalp care helps reduce irritation and improves treatment outcomes.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: You may notice improvement in itching and flaking within a few days, but visible reduction in scaling typically takes 2 to 4 weeks of regular use.

Q: Can I use this medicine every day?

A: It is usually recommended twice weekly for initial treatment. Using it daily may irritate the scalp. Follow your doctor's advice.

Q: Is it safe for colored or treated hair?

A: It is generally safe, but it may cause temporary changes in hair texture. Use a gentle conditioner if needed.

Q: Can I use it on my face?

A: This product is formulated for the scalp. Use on other areas only if advised by a doctor.

Q: What if I miss a dose?

A: If you miss a scheduled application, use it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the amount.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I use this medicine every day?
  • Will it affect my hair color?
  • Can I use it during pregnancy?
  • Does it interact with other hair products?
  • What if I miss a dose?
  • Can I use it on my face?
  • How long can I use it safely?

🔄 Substitutes for k druf 100 ml lotion

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: This shampoo can cure dandruff permanently.
    Fact: It controls dandruff and seborrheic dermatitis but does not cure the underlying tendency. Regular maintenance use may be needed.
  • Myth: More frequent use gives faster results.
    Fact: Using more often than directed can irritate the scalp. Follow the recommended schedule.
  • Myth: It is safe to use on the face without doctor's advice.
    Fact: It is formulated for the scalp. Use on other areas only if advised by a doctor.

🔄 Alternative Options

Generic Alternatives

  • Ketoconazole 2% shampoo
  • Zinc pyrithione 1% shampoo
  • Ketoconazole 2% + zinc pyrithione 1% shampoo (generic)

📊 Comparison with Similar Medicines

[{"medicine":"This medicine (Ketoconazole 2% + Zinc pyrithione 1%)","active_ingredient":"Ketoconazole + Zinc pyrithione","primary_use":"Dandruff, seborrheic dermatitis","frequency":"Twice weekly initially"},{"medicine":"Ketoconazole 2% shampoo","active_ingredient":"Ketoconazole","primary_use":"Dandruff, seborrheic dermatitis","frequency":"Twice weekly initially"},{"medicine":"Zinc pyrithione 1% shampoo","active_ingredient":"Zinc pyrithione","primary_use":"Dandruff","frequency":"Daily to twice weekly"}]

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