Atheronil R 10mg/75mg Capsule: Complete Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Blood in stool or vomit
- Severe abdominal pain
- Chest pain or difficulty breathing
- Severe headache with visual changes
- Sudden swelling of face, lips, or throat
- Yellowing of skin or eyes
- Decreased urine output
- Unexplained muscle pain, tenderness, or weakness, especially with fever or dark urine
- Unusual bruising or bleeding that does not stop
If experiencing severe symptoms, call emergency services immediately.
What is jupicent cv 10mg/75mg capsule used for?
This medicine is a combination of Rosuvastatin (a statin) and Clopidogrel (an antiplatelet agent) used to lower cholesterol and prevent blood clots in patients with cardiovascular disease. It is taken orally once daily as prescribed by a doctor.
- Generic Name: Rosuvastatin (10mg) + Clopidogrel (75mg)
- Manufacturer: Bricent Healthcare Pvt Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 jupicent cv 10mg/75mg capsule के बारे में (Hindi Summary)
उपयोग: यह दवा रोसुवास्टेटिन और क्लोपिडोग्रेल का संयोजन है। इसका उपयोग कोलेस्ट्रॉल को कम करने और रक्त के थक्के बनने से रोकने के लिए किया जाता है। यह उन रोगियों के लिए निर्धारित की जाती है जिन्हें दिल का दौरा, स्ट्रोक या धमनी रोग है। यह दवा दिल के दौरे और स्ट्रोक के जोखिम को कम करने में मदद करती है। इसे डॉक्टर के निर्देशानुसार ही लें।
साइड इफेक्ट्स: आम दुष्प्रभावों में सिरदर्द, मांसपेशियों में दर्द, पेट दर्द, अपच, दस्त और आसानी से चोट लगना या खून बहना शामिल हैं। गंभीर दुष्प्रभावों में गंभीर मांसपेशियों का टूटना, यकृत की क्षति और गंभीर रक्तस्राव शामिल हैं। यदि आपको असामान्य मांसपेशीय दर्द, कमजोरी, या काले मल जैसे लक्षण दिखें तो तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: इस दवा को डॉक्टर के निर्देशानुसार ही लें। बिना डॉक्टर की सलाह के इसे बंद न करें, खासकर दिल के दौरे या स्टेंट के बाद। सभी स्वास्थ्य सेवा प्रदाताओं को बताएं कि आप यह दवा ले रहे हैं, विशेष रूप से किसी भी सर्जरी या दंत प्रक्रिया से पहले। शराब का सेवन सीमित करें। बिना डॉक्टर की सलाह के अन्य रक्त पतला करने वाली दवाएं या NSAIDs न लें। नियमित रक्त परीक्षण की आवश्यकता हो सकती है।
💊 jupicent cv 10mg/75mg capsule Uses & Benefits
[{"condition":"Acute coronary syndrome","description":"Used to prevent blood clots and manage cholesterol in patients after a heart attack or unstable angina.","evidence":"Well-established"},{"condition":"Ischemic stroke or transient ischemic attack","description":"Helps prevent recurrent strokes and manages cholesterol levels.","evidence":"Well-established"},{"condition":"Peripheral artery disease","description":"Reduces the risk of cardiovascular events and improves blood flow.","evidence":"Well-established"},{"condition":"Hyperlipidemia","description":"Lowers LDL cholesterol and triglycerides while increasing HDL cholesterol.","evidence":"Well-established"}]
Off-label uses: [{"condition":"Secondary prevention in patients with multiple cardiovascular risk factors","description":"Sometimes prescribed off-label for patients with diabetes and multiple risk factors but no established cardiovascular disease.","evidence":"Limited"}]
Primary treatment for: Cardiovascular disease prevention
Also treats: Hyperlipidemia, Acute coronary syndrome, Ischemic stroke, Peripheral artery disease
📋 Drug Information
| Generic Name(s) | Rosuvastatin (10mg) + Clopidogrel (75mg) |
| Brand Name | jupicent cv 10mg/75mg capsule |
| Manufacturer | Bricent Healthcare Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | CARDIAC |
| Action Class | |
| Route of Administration | Oral |
| Storage | Store at room temperature between 15°C and 30°C (59°F to 86°F). Keep in a dry place, away from direct sunlight and moisture. Keep out of reach of children. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine combines two active ingredients with complementary mechanisms. Rosuvastatin selectively inhibits HMG-CoA reductase, the enzyme responsible for converting HMG-CoA to mevalonate, a rate-limiting step in cholesterol biosynthesis. This inhibition leads to upregulation of LDL receptors on hepatocytes, increasing clearance of LDL cholesterol from the blood. Clopidogrel is a prodrug that requires activation by hepatic cytochrome P450 enzymes. Its active metabolite irreversibly binds to the P2Y12 ADP receptor on platelets, preventing ADP-mediated activation of the glycoprotein IIb/IIIa complex, which is necessary for platelet aggregation. Together, these actions reduce cholesterol levels and inhibit platelet aggregation, lowering the risk of cardiovascular events.
Mechanism Steps
💡 How to Take jupicent cv 10mg/75mg capsule
Strength: Capsule containing Rosuvastatin 10 mg and Clopidogrel 75 mg.
Dosage Information
| Adult Dosage | The usual adult dose is one capsule containing Rosuvastatin 10 mg and Clopidogrel 75 mg taken orally once daily, with or without food. However, the dose must be individualized by a qualified clinician based on the indication, age, weight, renal and hepatic function, and other medications. Do not adjust the dose without consulting your doctor. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients may be more sensitive to the effects of this medicine, especially bleeding risk. Dose selection should be cautious, and renal function should be monitored. No specific dose adjustment is recommended, but individualization is necessary. |
| Renal Impairment | For patients with severe renal impairment (creatinine clearance <30 mL/min), rosuvastatin dose should not exceed 10 mg. Clopidogrel does not require dose adjustment in renal impairment, but caution is advised due to increased bleeding risk. |
| Hepatic Impairment | Rosuvastatin is contraindicated in patients with active liver disease or unexplained persistent transaminase elevations. Clopidogrel should be used with caution in patients with severe hepatic impairment. Dose adjustment may be necessary. |
| Maximum Daily Dose | The maximum recommended daily dose is Rosuvastatin 10 mg and Clopidogrel 75 mg as a fixed-dose combination. Higher doses of rosuvastatin may be used separately under medical supervision. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of jupicent cv 10mg/75mg capsule
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | |
| NSAIDs | Major | |
| Omeprazole | Major | |
| Gemfibrozil | Major | |
| Ketoconazole | Major | |
| Antacids | Moderate | |
| Fusidic acid | Moderate | |
| Colchicine | Moderate | |
| Ritonavir | Moderate | |
| Grapefruit juice | Minor |
🚨 Major Interactions
- Warfarin
- NSAIDs (e.g., ibuprofen, naproxen)
- Omeprazole
- CYP3A4 inhibitors (e.g., ketoconazole, clarithromycin)
- Gemfibrozil
⚡ Moderate Interactions
- Antacids (aluminum/magnesium hydroxide)
- Fusidic acid
- Colchicine
- Protease inhibitors (e.g., ritonavir)
🍷 Alcohol Interaction
Alcohol may increase the risk of liver problems and gastrointestinal bleeding when taken with this medicine. It is advisable to limit or avoid alcohol consumption while on this medication.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Active pathological bleeding such as peptic ulcer or intracranial hemorrhage","Hypersensitivity to rosuvastatin, clopidogrel, or any component of the formulation","Active liver disease or unexplained persistent elevations of serum transaminases","Pregnancy and breastfeeding","Severe renal impairment (creatinine clearance
⚠️ Warnings & Precautions
["Increased risk of bleeding: Monitor for signs of bleeding, especially during concomitant use with anticoagulants, NSAIDs, or other antiplatelet agents.","Muscle effects: Rosuvastatin can cause myopathy and rhabdomyolysis. Advise patients to report unexplained muscle pain, tenderness, or weakness.","Liver enzyme abnormalities: Monitor liver function tests. Discontinue if serious liver injury with clinical symptoms occurs.","CYP2C19 poor metabolizers: Clopidogrel may have reduced efficacy in patients who are poor metabolizers of CYP2C19.","Discontinuation before surgery: Clopidogrel should be stopped 5 to 7 days before elective surgery to reduce bleeding risk, unless otherwise directed by a cardiologist.","Thrombotic thrombocytopenic purpura (TTP): Rare but serious condition reported with clopidogrel. Seek immediate medical attention if symptoms occur."]
🤱 Lactation Safety
Not established from the available information. Rosuvastatin is contraindicated during breastfeeding. Clopidogrel may pass into breast milk. Consult your doctor before breastfeeding.
💊 Overdose Management
Overdose may increase the risk of bleeding and muscle toxicity. There is no specific antidote for clopidogrel; platelet transfusion may be considered to reverse its antiplatelet effect. For rosuvastatin, symptomatic and supportive care is recommended. Monitor liver function and creatine kinase levels. Seek immediate medical attention if overdose is suspected.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up.
Additional Safety Advice
Take this medicine exactly as prescribed by your doctor. Do not stop taking it without consulting your doctor, especially after a recent heart attack or stent placement, as stopping clopidogrel suddenly can increase the risk of blood clots. Inform all your healthcare providers that you are taking this medicine, especially before any surgery or dental procedure. Avoid activities that increase the risk of bleeding or injury. Limit alcohol consumption as it can increase the risk of liver problems and bleeding. Do not take other blood thinners or NSAIDs without your doctor's approval. Regular blood tests may be needed to monitor your liver function, cholesterol levels, and bleeding risk. If you miss a dose, take it as soon as you remember, but if it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients may be at higher risk of bleeding and muscle side effects. Regular monitoring of renal function, liver function, and bleeding signs is recommended. Dose adjustment may be necessary based on individual tolerance.
🤰 Pregnancy Planning (TTC)
This medicine is contraindicated during pregnancy. If you are planning to become pregnant, consult your doctor to discuss alternative treatments. Effective contraception should be used while taking this medicine.
🏥 Post-Surgery Considerations
Clopidogrel increases bleeding risk during and after surgery. It should be stopped 5 to 7 days before elective surgery, unless otherwise directed by your cardiologist. Inform your surgeon that you are taking this medicine.
🦷 Dental Procedures
Inform your dentist that you are taking this medicine before any dental procedure. Clopidogrel may increase bleeding during dental work. Your dentist may recommend precautions or consult with your doctor.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Regular exercise is encouraged, but avoid activities that increase the risk of bleeding or injury, such as contact sports. If you experience muscle pain or weakness, consult your doctor before continuing strenuous exercise.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause dizziness or fatigue in some people. If you experience these effects, avoid driving or operating heavy machinery until you know how the medicine affects you. Otherwise, it should not significantly impact your daily activities.
🛑 When to Stop This Medicine
Do not stop taking this medicine without consulting your doctor. If you experience serious side effects such as severe bleeding, muscle breakdown, or liver injury, your doctor may advise stopping the medicine. Always follow your doctor's guidance.
📅 Long-Term Use Effects
Long-term use of this medicine is generally safe and effective for reducing cardiovascular risk. Regular monitoring of liver function, lipid profile, and bleeding signs is recommended. Prolonged use may increase the risk of bleeding, muscle problems, and liver enzyme abnormalities. Your doctor will periodically assess the benefit-risk balance and may adjust the dose or discontinue if necessary.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Diet and exercise can help manage cholesterol and reduce cardiovascular risk.
Evidence: Well-establishedAtorvastatin or simvastatin may be used as alternatives to rosuvastatin.
Evidence: Well-establishedTicagrelor or prasugrel may be used instead of clopidogrel in certain patients.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
No specific vaccine interactions are established. However, inform your healthcare provider about this medicine before receiving any vaccine. Live vaccines should be avoided if you are on immunosuppressive therapy, but this medicine is not immunosuppressive.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✅ DO
Keep out of reach of children
❌ DON'T
Do not use after expiry date
✈️ Traveling with This Medicine
When traveling, carry this medicine in its original packaging with a copy of your prescription. Keep it in your carry-on luggage to avoid loss. Store at room temperature and protect from extreme heat or cold. If crossing time zones, continue taking your dose at the same local time as usual, but consult your doctor if you are unsure. Check customs regulations for carrying prescription medicines.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: Rosuvastatin starts lowering cholesterol within 1 week, with maximum effect in 2 to 4 weeks. Clopidogrel inhibits platelet aggregation within 2 hours, with maximum effect after 3 to 7 days of repeated dosing.
A: Yes, you can take it with or without food. Taking it with food may reduce stomach upset.
A: If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose.
A: Do not stop taking this medicine without consulting your doctor. Stopping suddenly, especially clopidogrel, can increase the risk of blood clots, heart attack, or stroke.
A: This medicine is not recommended during pregnancy as it may harm the fetus. Consult your doctor if you are pregnant or planning to become pregnant.
🤔 Common Patient Concerns
🔄 Substitutes for jupicent cv 10mg/75mg capsule
View AllAlternative brands with exact same active ingredient:
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arvat cv 10mg/75mg tabletConcertina Pharma Pvt Ltd ₹55.31 62.4% CHEAPER
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stayhappi rosuvastatin+clopidogrel 10mg/75mg capsuleSarvagunaushdhi Pvt Ltd ₹62.00 57.9% CHEAPER
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roslong cv 10mg/75mg tabletSunmarker Pharma ₹93.75 36.3% CHEAPER
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roznova cv capsuleAstranova Biotech ₹103.13 29.9% CHEAPER
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custatc 10mg/75mg tabletCubit Healthcare ₹110.00 25.3% CHEAPER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can be stopped once cholesterol levels are normal.
Fact: This medicine is usually continued long-term to maintain cholesterol levels and prevent cardiovascular events. Stopping suddenly can increase the risk of heart attack or stroke. - Myth: This medicine causes severe muscle damage in everyone.
Fact: Muscle side effects are uncommon and usually mild. Severe muscle damage (rhabdomyolysis) is rare. Report any muscle pain to your doctor. - Myth: Taking this medicine means I can eat whatever I want.
Fact: This medicine works best when combined with a healthy diet and lifestyle. A balanced diet low in saturated fats is recommended.
🔄 Alternative Options
Generic Alternatives
- Rosuvastatin 10 mg + Clopidogrel 75 mg generic capsules
Brand Alternatives
- Atheronil R 10mg/75mg Capsule