juflox c 100mg/100mg tablet - Cefixime (100mg) + Ofloxacin (100mg) medicine

Alencef O Kid Tablet: Comprehensive Medicine Guide

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🏭 Medicross Pharmaceuticals 📦 Varies by brand 💊 Allopathy 📅 Updated: Sep 26, 2026
📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Moderate to well-established for specific indications.
Reviewed by
SaathiMed Expert Panel | Sep 26, 2026
🩺
Medically Fact-Checked & Clinically Verified by SaathiMed Clinical Review Board
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026

When to Call Your Doctor IMMEDIATELY

  • Difficulty breathing or swelling of face, lips, or throat
  • Severe or bloody diarrhea
  • Tendon pain or swelling
  • Seizures or confusion
  • Yellowing of eyes or skin
  • Decreased urine output

If experiencing severe symptoms, call emergency services immediately.

What is juflox c 100mg/100mg tablet used for?

This medicine is a combination antibiotic containing Cefixime and Ofloxacin, used to treat bacterial infections in children. It works by killing bacteria and should be taken exactly as prescribed.

  • Generic Name: Cefixime (100mg) + Ofloxacin (100mg)
  • Manufacturer: Medicross Pharmaceuticals
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 juflox c 100mg/100mg tablet के बारे में (Hindi Summary)

उपयोग: यह दवा सेफिक्सिम और ऑफ्लोक्सासिन का संयोजन है, जिसका उपयोग बच्चों में बैक्टीरियल संक्रमण जैसे मूत्र मार्ग संक्रमण, श्वसन तंत्र संक्रमण और त्वचा संक्रमण के इलाज के लिए किया जाता है। यह बैक्टीरिया को मारकर काम करती है।

साइड इफेक्ट्स: आम दुष्प्रभावों में मतली, उल्टी, दस्त, पेट दर्द और सिरदर्द शामिल हैं। गंभीर दुष्प्रभाव दुर्लभ हैं लेकिन एलर्जी, टेंडन टूटना, दौरे आदि हो सकते हैं। किसी भी गंभीर लक्षण पर तुरंत डॉक्टर से संपर्क करें।

सुरक्षा सलाह: इस दवा का उपयोग केवल डॉक्टर के पर्चे पर ही करें। बच्चे को पर्याप्त पानी पिलाएं। दवा का पूरा कोर्स करें। एंटासिड या आयरन सप्लीमेंट के साथ 2 घंटे का अंतर रखें। दवा को ठंडी और सूखी जगह पर रखें।

💡 Did You Know? The Indian pharmaceutical market is expected to reach $130 billion by 2030.

💊 juflox c 100mg/100mg tablet Uses & Benefits

[{"condition":"Urinary tract infections","description":"Used to treat bacterial infections of the urinary tract in children, caused by susceptible organisms.","evidence":"Well-established"},{"condition":"Respiratory tract infections","description":"Effective against certain bacterial respiratory infections such as bronchitis and pneumonia, when caused by susceptible bacteria.","evidence":"Well-established"},{"condition":"Skin and soft tissue infections","description":"Used for bacterial skin infections like cellulitis and abscesses, when appropriate.","evidence":"Moderate"},{"condition":"Typhoid fever","description":"Sometimes used in the treatment of typhoid fever caused by Salmonella typhi, though resistance patterns vary.","evidence":"Moderate"}]

Off-label uses: [{"condition":"Gonorrhea","description":"Ofloxacin component may be used off-label for uncomplicated gonorrhea, but cefixime is more commonly used.","evidence":"Limited"}]

Primary treatment for: Bacterial infections

Also treats: Urinary tract infections, Respiratory tract infections, Skin infections, Typhoid fever

📋 Drug Information

Generic Name(s)Cefixime (100mg) + Ofloxacin (100mg)
Brand Namejuflox c 100mg/100mg tablet
ManufacturerMedicross Pharmaceuticals
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassANTI INFECTIVES
Action Class
Route of AdministrationOral
StorageStore at room temperature (15-30°C) in a dry place, away from direct sunlight. Keep out of reach of children.
Shelf Life24 months from the date of manufacture.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Always prescribe this combination only when a bacterial infection is confirmed or strongly suspected.
2
Adjust the dose based on the child's weight and renal function.
3
Advise parents to complete the full course even if the child feels better.
4
Warn about the risk of tendon rupture and advise avoiding strenuous activity.
5
Instruct to separate antacids and iron supplements by at least 2 hours.
6
Monitor for signs of allergic reactions and superinfections.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅
Fever with painful urination
This medicine is commonly prescribed for urinary tract infections.
Likely Use
✅
Cough with yellow sputum
May be used for bacterial respiratory infections.
Likely Use
❌
Runny nose and sneezing
This medicine is not effective for viral infections like common cold.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionCefixime is absorbed from the gastrointestinal tract, with bioavailability of about 40-50% for the suspension and 50% for tablets. Ofloxacin is well absorbed orally, with bioavailability of approximately 98%. Food may slightly delay absorption but does not significantly affect the extent.
DistributionCefixime distributes widely into body tissues and fluids, including the respiratory tract, urine, and bile. Ofloxacin also distributes widely, achieving high concentrations in urine, prostate, and lung tissue. Both drugs have moderate protein binding.
Protein BindingCefixime is about 65% protein-bound; Ofloxacin is about 20-30% protein-bound.
MetabolismCefixime is not significantly metabolized. Ofloxacin undergoes limited metabolism in the liver, with less than 10% metabolized.
Half-LifeCefixime half-life is approximately 3-4 hours. Ofloxacin half-life is about 4-5 hours in adults with normal renal function.
ExcretionCefixime is primarily excreted unchanged in urine (about 50%) and bile. Ofloxacin is mainly excreted unchanged in urine (about 70-80%).
BioavailabilityCefixime: 40-50%; Ofloxacin: approximately 98%.
Onset of ActionOnset of action is typically within 1-2 hours after oral administration, but clinical improvement may take 24-48 hours.
Peak Plasma TimeCefixime: 2-4 hours; Ofloxacin: 1-2 hours.
Duration of ActionThe duration of action depends on the dosing interval; both drugs are usually dosed every 12 hours, providing coverage for about 12 hours.

How It Works

This medicine combines two antibiotics with different mechanisms. Cefixime, a cephalosporin, inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins, leading to cell lysis. Ofloxacin, a fluoroquinolone, inhibits DNA gyrase and topoisomerase IV, enzymes required for DNA replication, transcription, and repair, causing bacterial cell death. The combination provides a broader spectrum of activity against various gram-positive and gram-negative bacteria.

Mechanism Steps

1
Cefixime binds to PBPs: Cefixime binds to penicillin-binding proteins on the bacterial cell wall, inhibiting peptidoglycan cross-linking.
2
Cell wall lysis: Inhibition of cell wall synthesis leads to weakening of the bacterial cell wall and eventual lysis.
3
Ofloxacin inhibits DNA gyrase: Ofloxacin binds to DNA gyrase and topoisomerase IV, blocking DNA replication and transcription.
4
Bacterial death: The combined actions result in rapid bacterial cell death.

💡 How to Take juflox c 100mg/100mg tablet

Strength: Tablet containing Cefixime 100 mg and Ofloxacin 100 mg.

1Take this medicine orally with a glass of water.
2It can be taken with or without food, but taking with food may reduce stomach upset.
3Swallow the tablet whole; do not crush or chew.
4Take at evenly spaced intervals, usually every 12 hours.
5Complete the full course as prescribed by the doctor.

Dosage Information

Adult DosageThis medicine is primarily intended for pediatric use. For adults, the dose is determined by the doctor based on the type and severity of infection, renal function, and other factors. Typically, cefixime 200-400 mg/day and ofloxacin 200-400 mg/day are used in divided doses. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function.
Pediatric DosageThe dose is based on the child's weight and the severity of infection. Typically, cefixime 8 mg/kg/day and ofloxacin 10-15 mg/kg/day in divided doses every 12 hours. However, ofloxacin is generally not recommended in children unless the benefits outweigh the risks. Dose must be individualized by a pediatrician.
Elderly DosageElderly patients may have reduced renal function; dose adjustment may be necessary based on creatinine clearance. Use with caution due to increased risk of tendon rupture and CNS effects.
Renal ImpairmentDose adjustment is required in patients with renal impairment. For creatinine clearance less than 30 mL/min, reduce dose or extend dosing interval. Consult a doctor for specific guidance.
Hepatic ImpairmentNo specific dose adjustment is generally required for mild to moderate hepatic impairment. Use with caution in severe hepatic impairment.
Maximum Daily DoseThe maximum daily dose should not exceed the recommended adult dose of cefixime 400 mg and ofloxacin 400 mg. For children, the maximum is based on weight and should not exceed adult dose.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With food
Take with meals
Reduces stomach upset.
Dairy
Can take together
No significant interaction.

⏰ What to Do If You Miss a Dose

📌 Less than 6 hours since missed dose
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than 6 hours since missed dose
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of juflox c 100mg/100mg tablet

✅ Common Side Effects

Nausea (Common (5-10%))
Give with food to reduce nausea. Consult doctor if persistent.
Diarrhea (Common (5-10%))
Ensure adequate fluid intake. Consult doctor if severe or bloody.
Abdominal pain (Common (5-10%))
Usually temporary. Consult doctor if severe.
Headache (Common (5-10%))
May resolve on its own. Consult doctor if persistent.
Rash (Uncommon (1-5%))
Stop medicine and consult doctor if rash develops.

🚨 Serious Side Effects

Severe allergic reaction (anaphylaxis) (Rare (<0.1%))
Seek immediate medical attention if swelling of face, lips, throat, or difficulty breathing occurs.
Tendon rupture (Rare (<0.1%))
Stop medicine and seek medical help if tendon pain or swelling occurs.
Clostridioides difficile-associated diarrhea (Rare (<0.1%))
Seek medical attention if severe, persistent, or bloody diarrhea occurs.
Seizures (Rare (<0.1%))
Seek immediate medical attention if seizures occur.
Peripheral neuropathy (Rare (<0.1%))
Report numbness, tingling, or burning sensation to doctor.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Antacids Major
Warfarin Major
Theophylline Major
NSAIDs Major
Corticosteroids Moderate
Oral hypoglycemics Moderate
Probenecid Moderate
Iron supplements Minor
Zinc supplements Minor
Caffeine Minor

🚨 Major Interactions

  • Antacids containing magnesium or aluminum
  • Warfarin
  • Theophylline
  • NSAIDs

⚡ Moderate Interactions

  • Corticosteroids
  • Oral hypoglycemics
  • Probenecid

🍷 Alcohol Interaction

Alcohol should be avoided while taking this medicine, as it may increase the risk of central nervous system side effects such as dizziness, drowsiness, and seizures.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Known allergy to cephalosporins or fluoroquinolones","History of tendon disorders with fluoroquinolones","Myasthenia gravis","Severe renal impairment (dose adjustment needed)","Children under 6 months for cefixime; ofloxacin not recommended in children under 18 except for specific indications"]

⚠️ Warnings & Precautions

["Use with caution in patients with renal impairment; dose adjustment may be needed.","May cause dizziness; avoid driving or operating machinery until you know how it affects you.","Avoid exposure to sunlight; may cause photosensitivity.","May worsen muscle weakness in patients with myasthenia gravis.","Prolonged use may lead to superinfection with resistant organisms.","Ensure adequate hydration to prevent crystalluria."]

🤱 Lactation Safety

Cefixime is excreted in breast milk in low amounts and is generally considered safe. Ofloxacin is also excreted in breast milk; caution is advised. Consult a doctor before use during breastfeeding.

💊 Overdose Management

Overdose may cause nausea, vomiting, diarrhea, and seizures. Treatment is symptomatic and supportive. Gastric lavage may be considered if ingestion is recent. There is no specific antidote. Maintain hydration and monitor renal function.

⏰ Missed Dose

If a dose is missed, give it as soon as remembered. If it is almost time for the next dose, skip the missed dose and continue with the regular schedule. Do not double the dose.

Additional Safety Advice

General Safety

This medicine should only be used when prescribed by a doctor for a confirmed or strongly suspected bacterial infection. Do not use it for viral infections. Inform your doctor if the child has any allergies, kidney problems, liver problems, or a history of tendon disorders. Ensure the child stays well hydrated during treatment. Do not exceed the prescribed dose or duration. Complete the full course even if symptoms improve. Avoid giving antacids or iron supplements within 2 hours of this medicine, as they can reduce absorption. Store the tablets in a cool, dry place away from direct sunlight. Keep out of reach of children. If a dose is missed, give it as soon as remembered, but if it is almost time for the next dose, skip the missed dose and continue the regular schedule. Do not double the dose.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients are at higher risk of tendon rupture, CNS effects, and renal impairment. Dose adjustment and close monitoring are recommended.

🤰 Pregnancy Planning (TTC)

Consult a doctor before planning pregnancy if taking this medicine. Cefixime is generally safe, but ofloxacin should be avoided unless necessary.

🏥 Post-Surgery Considerations

This medicine may be prescribed to prevent or treat surgical site infections. Follow the doctor's instructions carefully.

🦷 Dental Procedures

Inform your dentist if you are taking this medicine, as it may interact with other medications or affect healing.

💚 Lifestyle Tips for Better Results

🏃
Ensure the child drinks plenty of fluids.
🥗
Maintain good hygiene to prevent infections.
😴
Encourage a balanced diet to support immunity.
💧
Ensure adequate rest during illness.
🧘
Avoid close contact with others to prevent spread of infection.

🏋️ Exercise Considerations

Children should avoid strenuous physical activity while taking this medicine due to the risk of tendon rupture associated with ofloxacin.

🥗 Diet Recommendations

Offer bland, easy-to-digest foods if nausea occurs.
Include yogurt or probiotics to prevent diarrhea.
Avoid caffeine-containing beverages.
Ensure adequate hydration.

💼 Impact on Daily Work & Life

This medicine may cause dizziness or drowsiness in some children. It is advisable to avoid activities requiring mental alertness, such as cycling or sports, until the effect is known.

🛑 When to Stop This Medicine

Do not stop this medicine without consulting the doctor, even if symptoms improve. Complete the full prescribed course. If serious side effects occur, stop and seek medical advice immediately.

📅 Long-Term Use Effects

Long-term use of this medicine may lead to antibiotic resistance, superinfections, and rare side effects like tendon damage or peripheral neuropathy. Regular monitoring of renal and liver function may be required if used for prolonged periods.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Probiotics

May help prevent antibiotic-associated diarrhea.

Evidence: Moderate
Increased fluid intake

Helps flush out bacteria in urinary tract infections.

Evidence: Well-established

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

Antibiotics may reduce the effectiveness of live bacterial vaccines like typhoid vaccine. Consult a doctor regarding vaccination timing.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

Carry this medicine in its original packaging with a copy of the prescription. Store at room temperature and protect from direct sunlight. If traveling across time zones, adjust dosing intervals as advised by your doctor. Check customs regulations for carrying prescription medicines.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 5-year-old child with recurrent urinary tract infection
The child was prescribed this medicine for 7 days. The parents ensured the child took it with food and stayed hydrated. Symptoms improved within 3 days, and the full course was completed without side effects.
💡 Lesson: Adhering to the prescribed dose and duration is crucial for cure and preventing resistance.
👤 An 8-year-old with skin infection
After a minor injury, the child developed a skin infection. The doctor prescribed this medicine. The parents noticed mild nausea initially, which subsided when given with food. The infection resolved completely.
💡 Lesson: Taking the medicine with food can reduce gastrointestinal side effects.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: Improvement in symptoms is usually seen within 24-48 hours, but the full course must be completed.

Q: Can I give this medicine with milk?

A: Yes, it can be taken with milk, but it is best to give with food to reduce stomach upset.

Q: What if my child misses a dose?

A: Give the missed dose as soon as remembered, but if it is almost time for the next dose, skip it and continue the regular schedule. Do not double the dose.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can this medicine be given to infants?
  • What if my child vomits after taking the medicine?
  • Are there any food restrictions?
  • Can this medicine cause drowsiness?
  • How long does it take to show effect?
  • Is it safe to take with other medicines?

🔄 Substitutes for juflox c 100mg/100mg tablet

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: Antibiotics can cure viral infections like colds.
    Fact: Antibiotics only work against bacteria, not viruses.
  • Myth: You can stop taking antibiotics once you feel better.
    Fact: You must complete the full course to prevent resistance and relapse.

🔄 Alternative Options

Generic Alternatives

  • Cefixime + Ofloxacin generic tablets

Brand Alternatives

  • Alencef O Kid Tablet

📊 Comparison with Similar Medicines

[{"medicine":"Cefixime + Ofloxacin","composition":"Cefixime 100mg + Ofloxacin 100mg","uses":"Bacterial infections","notes":"Combination broad-spectrum"},{"medicine":"Cefixime alone","composition":"Cefixime 100mg","uses":"Respiratory, urinary infections","notes":"Narrower spectrum"},{"medicine":"Ofloxacin alone","composition":"Ofloxacin 100mg","uses":"Urinary, respiratory infections","notes":"Fluoroquinolone"}]

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