Floxant 300 Tablet (Ofloxacin 300 mg): Complete Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Sudden pain, swelling, or inability to move a joint, especially the Achilles tendon.
- Tingling, numbness, burning, or weakness in the arms or legs.
- Severe diarrhea that may contain blood or mucus.
- Swelling of the face, lips, tongue, or throat, or difficulty breathing.
- Palpitations, fainting, or irregular heartbeat.
- Yellowing of the skin or eyes, dark urine, or severe fatigue.
- Seizures or severe confusion.
- Decreased urine output or blood in urine.
If experiencing severe symptoms, call emergency services immediately.
What is juflox 300mg tablet used for?
This medicine is an antibiotic containing Ofloxacin 300 mg, used to treat bacterial infections such as urinary tract infections, prostatitis, and skin infections. It works by killing bacteria and should be taken exactly as prescribed by a doctor.
- Generic Name: Ofloxacin (300mg)
- Manufacturer: Medicross Pharmaceuticals
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 juflox 300mg tablet के बारे में (Hindi Summary)
उपयोग: यह दवा ओफ्लोक्सासिन 300 मिलीग्राम नामक एंटीबायोटिक है, जिसका उपयोग बैक्टीरियल संक्रमणों के इलाज के लिए किया जाता है। यह मूत्र मार्ग संक्रमण, प्रोस्टेट संक्रमण, त्वचा संक्रमण, और कुछ यौन संचारित रोगों के इलाज में प्रभावी है। यह दवा बैक्टीरिया को मारकर काम करती है और डॉक्टर के निर्देशानुसार ही लेनी चाहिए।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में मतली, उल्टी, दस्त, पेट दर्द, सिरदर्द, और चक्कर आना शामिल हैं। गंभीर दुष्प्रभावों में टेंडन टूटना, तंत्रिका क्षति, गंभीर एलर्जी, और दिल की धड़कन में गड़बड़ी हो सकती है। कोई भी असामान्य लक्षण दिखने पर तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: इस दवा को लेने से पहले अपने डॉक्टर को अपनी सभी स्वास्थ्य समस्याओं और दवाओं के बारे में बताएं। एंटासिड, दूध, या खनिज सप्लीमेंट के साथ इस दवा को न लें, क्योंकि इससे दवा का असर कम हो सकता है। पर्याप्त पानी पिएं और धूप से बचें। गर्भवती या स्तनपान कराने वाली महिलाएं डॉक्टर से सलाह लें। शराब का सेवन न करें।
💊 juflox 300mg tablet Uses & Benefits
- [{"condition":"Urinary tract infections","description":"This medicine is used to treat infections of the bladder and kidneys caused by susceptible bacteria.
- It helps relieve symptoms such as burning during urination, frequent urination, and lower abdominal pain.","evidence":"Well-established"},{"condition":"Prostatitis","description":"This medicine is effective against bacterial prostatitis because it penetrates well into prostate tissue.
- It helps reduce pain, fever, and urinary symptoms.","evidence":"Well-established"},{"condition":"Skin and soft tissue infections","description":"This medicine is prescribed for certain bacterial skin infections, including cellulitis and abscesses, when the bacteria are susceptible to Ofloxacin.","evidence":"Well-established"},{"condition":"Sexually transmitted infections","description":"This medicine is used to treat gonorrhea and chlamydia infections, often in combination with other antibiotics.
- It helps eradicate the bacteria and prevent complications.","evidence":"Well-established"},{"condition":"Respiratory tract infections","description":"This medicine may be used for certain bacterial respiratory infections, such as acute exacerbations of chronic bronchitis, when other antibiotics are not suitable.","evidence":"Moderate"},{"condition":"Gastrointestinal infections","description":"This medicine can be used to treat some bacterial diarrheal illnesses, including traveler's diarrhea, when caused by susceptible organisms.","evidence":"Moderate"}]
Off-label uses: [{"condition":"Tuberculosis (as part of combination therapy)","description":"Ofloxacin is sometimes used off-label as a second-line agent in multidrug-resistant tuberculosis regimens, but only under specialist supervision.","evidence":"Limited"},{"condition":"Epididymitis","description":"This medicine may be used off-label for epididymitis, an inflammation of the tube at the back of the testicle, when caused by susceptible bacteria.","evidence":"Limited"}]
Primary treatment for: Bacterial infections
Also treats: Urinary tract infections, Prostatitis, Skin infections, Sexually transmitted infections, Respiratory tract infections
📋 Drug Information
| Generic Name(s) | Ofloxacin (300mg) |
| Brand Name | juflox 300mg tablet |
| Manufacturer | Medicross Pharmaceuticals |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | ANTI INFECTIVES |
| Action Class | Quinolones/ Fluroquinolones |
| Route of Administration | Oral |
| Storage | Store this medicine at room temperature, between 15°C and 30°C (59°F and 86°F). Keep it away from direct sunlight, moisture, and heat. Do not store it in the bathroom. Keep it in its original container, tightly closed, and out of the reach of children and pets. |
| Shelf Life | The shelf life of this medicine is typically 24 to 36 months from the date of manufacture, depending on the manufacturer. Always check the expiry date on the packaging before use. Do not use the medicine after the expiry date has passed. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine works by inhibiting two essential bacterial enzymes: DNA gyrase (also called topoisomerase II) and topoisomerase IV. These enzymes are responsible for maintaining the supercoiled structure of bacterial DNA and for separating replicated DNA strands during cell division. By blocking these enzymes, this medicine prevents the bacteria from replicating and repairing their DNA, leading to bacterial cell death. This medicine is bactericidal, meaning it actively kills bacteria rather than just stopping their growth. Because it targets enzymes that are unique to bacteria, it has selective toxicity and generally does not harm human cells. However, resistance can develop if the bacteria mutate the genes encoding these enzymes or reduce the permeability of their cell walls to the medicine.
Mechanism Steps
💡 How to Take juflox 300mg tablet
Strength: This medicine is available as an immediate-release tablet containing 300 mg of Ofloxacin.
Dosage Information
| Adult Dosage | The usual adult dose of this medicine is 200 mg to 400 mg taken orally every 12 hours, depending on the type and severity of the infection. For uncomplicated urinary tract infections, a dose of 200 mg every 12 hours for 3 to 7 days is often used. For more serious infections, such as prostatitis or complicated urinary tract infections, 300 mg to 400 mg every 12 hours for 10 to 14 days may be prescribed. The exact dose, frequency, and duration must be individualized by a qualified clinician based on the indication, age, weight, kidney and liver function, and the susceptibility of the infecting bacteria. Always follow your doctor's prescription exactly and complete the full course. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. This medicine is generally not recommended for children and adolescents under 18 years of age due to the risk of joint and tendon damage, except in certain serious infections where the benefit outweighs the risk, as determined by a specialist. |
| Elderly Dosage | Elderly patients (above 65 years) may be more sensitive to the side effects of this medicine, especially tendon rupture, kidney problems, and central nervous system effects. Dose adjustment may be necessary based on kidney function. Elderly patients should be monitored closely for any signs of tendon pain, confusion, or falls. Always consult a doctor for appropriate dosing. |
| Renal Impairment | Patients with kidney impairment require dose adjustment. For patients with a creatinine clearance between 20 and 50 mL/min, the usual dose may be reduced or the dosing interval extended. For patients with a creatinine clearance below 20 mL/min, a lower dose or less frequent dosing is recommended. The exact adjustment must be determined by a qualified clinician based on the degree of kidney impairment and the indication. |
| Hepatic Impairment | Mild to moderate liver impairment generally does not require dose adjustment for this medicine, as it is primarily excreted unchanged by the kidneys. However, patients with severe liver disease should be monitored closely, and the dose may need to be adjusted based on clinical response and liver function tests. Consult a doctor for individualized dosing. |
| Maximum Daily Dose | The maximum recommended daily dose of this medicine is 800 mg per day, usually divided into two doses of 400 mg each. Do not exceed this dose unless specifically instructed by your doctor. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of juflox 300mg tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Antacids | Major | |
| Warfarin | Major | |
| Theophylline | Major | |
| NSAIDs | Major | |
| Corticosteroids | Major | |
| Antidiabetics | Moderate | |
| Caffeine | Moderate | |
| Cyclosporine | Moderate | |
| Probenecid | Moderate | |
| Didanosine | Minor |
🚨 Major Interactions
- Antacids, sucralfate, and mineral supplements containing aluminum, magnesium, calcium, iron, or zinc
- Warfarin and other anticoagulants
- Theophylline
- Nonsteroidal anti-inflammatory drugs (NSAIDs)
- Corticosteroids
⚡ Moderate Interactions
- Antidiabetic medicines (e.g., insulin, sulfonylureas)
- Caffeine
- Cyclosporine
- Probenecid
🍷 Alcohol Interaction
Alcohol should be avoided while taking this medicine. Both alcohol and this medicine can cause dizziness, drowsiness, and impaired judgment. Combining them may increase these effects and also raise the risk of stomach upset and liver problems. It is best to abstain from alcohol until you have completed the course and your doctor confirms it is safe.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Known allergy or hypersensitivity to Ofloxacin or any other fluoroquinolone antibiotic.","History of tendon disorders related to fluoroquinolone use.","Myasthenia gravis (may worsen muscle weakness).","Children and adolescents under 18 years of age, except when specifically prescribed by a specialist for certain serious infections.","Pregnancy and breastfeeding, unless the doctor determines it is essential.","Patients with known QT interval prolongation or uncorrected electrolyte imbalances."]
⚠️ Warnings & Precautions
["This medicine can cause tendon inflammation and rupture, especially in older adults, those taking corticosteroids, and organ transplant recipients. Stop the medicine and contact your doctor if you experience tendon pain or swelling.","Peripheral neuropathy (nerve damage) can occur and may be irreversible. Report any tingling, numbness, burning, or weakness in the arms or legs immediately.","This medicine can cause central nervous system effects, including dizziness, confusion, seizures, and hallucinations. Avoid driving or operating machinery until you know how it affects you.","Serious allergic reactions, including anaphylaxis, can occur. Seek emergency care if you experience swelling of the face, lips, tongue, or throat, or difficulty breathing.","This medicine can cause severe diarrhea associated with Clostridium difficile. Do not treat diarrhea with over-the-counter medicines without consulting your doctor.","Avoid excessive sun exposure and tanning beds, as this medicine can cause photosensitivity reactions.","Inform your doctor if you have kidney disease, liver disease, heart problems, diabetes, or myasthenia gravis before taking this medicine.","Do not take this medicine with antacids, sucralfate, or mineral supplements within 2 hours of dosing."]
🤱 Lactation Safety
This medicine passes into breast milk in small amounts. Because of the potential risk of serious side effects in nursing infants, including joint and tendon problems, breastfeeding is generally not recommended while taking this medicine. If treatment is essential, your doctor may advise you to pump and discard breast milk during therapy and for a few days after the last dose. Always consult your doctor before breastfeeding.
💊 Overdose Management
If you suspect an overdose of this medicine, seek emergency medical attention immediately. Symptoms of overdose may include nausea, vomiting, dizziness, confusion, seizures, and heart rhythm abnormalities. There is no specific antidote for Ofloxacin overdose. Treatment is supportive and may include activated charcoal if taken shortly after ingestion, intravenous fluids, and monitoring of vital signs and heart rhythm. Do not try to induce vomiting unless instructed by a healthcare professional.
⏰ Missed Dose
If you miss a dose of this medicine, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take two doses at the same time to make up for a missed dose. If you are unsure what to do, contact your doctor or pharmacist.
Additional Safety Advice
Before you start taking this medicine, tell your doctor about all your medical conditions, especially if you have kidney disease, liver disease, heart problems, diabetes, myasthenia gravis, or a history of tendon problems. Also inform your doctor about all other medicines, supplements, and herbal products you are taking, as this medicine can interact with many of them. Do not take antacids, multivitamins, or mineral supplements containing magnesium, aluminum, calcium, iron, or zinc within two hours before or after taking this medicine, as they can reduce its absorption. Take this medicine with plenty of water to help prevent crystals from forming in your urine. Avoid excessive sunlight and tanning beds, as this medicine can make your skin more sensitive to sunlight. Do not drive or operate heavy machinery if you feel dizzy or confused after taking this medicine. Avoid alcohol while taking this medicine, as it can increase the risk of dizziness and stomach upset. If you are pregnant, planning to become pregnant, or breastfeeding, discuss with your doctor before using this medicine. Do not share this medicine with others, even if they have similar symptoms. Keep this medicine out of the reach of children and store it as directed on the label.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients are at higher risk of tendon rupture, kidney impairment, and central nervous system effects from this medicine. Dose adjustment may be necessary based on kidney function. Elderly patients should be monitored closely for signs of tendon pain, confusion, dizziness, and falls. It is important to maintain adequate hydration and avoid concurrent use of corticosteroids, which further increase tendon rupture risk.
🤰 Pregnancy Planning (TTC)
If you are planning to become pregnant, discuss with your doctor before taking this medicine. Fluoroquinolones are generally avoided during pregnancy due to potential risks to fetal development. Your doctor may recommend alternative antibiotics that are safer for pregnancy. If you become pregnant while taking this medicine, contact your doctor immediately.
🏥 Post-Surgery Considerations
If you are scheduled for surgery, inform your surgeon and anesthesiologist that you are taking this medicine. It may interact with certain anesthetic agents and can affect heart rhythm. Your doctor may advise you to stop the medicine before surgery or adjust the dose. Do not stop the medicine without consulting your doctor.
🦷 Dental Procedures
Inform your dentist that you are taking this medicine before any dental procedure. This medicine may interact with certain antibiotics or anesthetics used in dentistry. It is important to maintain good oral hygiene and report any signs of infection, such as swelling or pain, to your dentist.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
While taking this medicine, avoid strenuous exercise or high-impact activities that could strain your tendons, especially if you are older or have a history of tendon problems. If you experience any joint or tendon pain, stop exercising and consult your doctor. Gentle stretching and low-impact activities like walking or swimming may be safe, but listen to your body and do not push through pain.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause dizziness, drowsiness, or confusion in some people. If you experience these effects, avoid driving, operating heavy machinery, or performing tasks that require mental alertness. Most people can continue their normal daily activities, but it is important to be aware of how the medicine affects you. If your work involves physical labor, be cautious about tendon strain and report any joint pain to your doctor.
🛑 When to Stop This Medicine
You should stop taking this medicine only after completing the full course prescribed by your doctor, even if you feel better. If you experience serious side effects such as tendon pain, severe diarrhea, allergic reactions, or heart rhythm problems, stop the medicine and seek immediate medical attention. Do not stop the medicine early without consulting your doctor, as this can lead to recurrence of the infection and antibiotic resistance.
📅 Long-Term Use Effects
Long-term use of this medicine can increase the risk of antibiotic resistance, tendon damage, peripheral neuropathy, and liver or kidney problems. It may also disrupt the normal balance of bacteria in the body, leading to secondary infections such as oral thrush or Clostridium difficile-associated diarrhea. Regular monitoring of kidney and liver function may be required if prolonged therapy is necessary. This medicine should only be used for as long as prescribed by your doctor.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Drinking plenty of water can help flush out bacteria from the urinary tract and support recovery from urinary tract infections.
Evidence: Well-establishedProbiotics may help prevent antibiotic-associated diarrhea and maintain healthy gut bacteria, but should be taken at least 2 hours apart from this medicine.
Evidence: ModerateCranberry juice or supplements may help prevent urinary tract infections, but they are not a treatment for active infections.
Evidence: Limited💉 Vaccination Considerations
💉 If You're Getting Vaccinated
This medicine does not interact with most vaccines. However, if you are scheduled to receive a live vaccine, inform your doctor, as antibiotics generally do not affect vaccine efficacy, but the underlying infection may. There are no specific vaccination requirements or restrictions while taking this medicine.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✅ DO
Keep out of reach of children
❌ DON'T
Do not use after expiry date
✈️ Traveling with This Medicine
When traveling with this medicine, carry it in its original packaging with the prescription label clearly visible. Bring a copy of your prescription or a letter from your doctor, especially for international travel, as some countries have strict rules about antibiotics. Store the medicine in a cool, dry place, away from direct sunlight and moisture. If you are crossing time zones, adjust your dosing schedule gradually to maintain even intervals, but do not double dose. Keep the medicine in your carry-on luggage to avoid loss or temperature extremes. Check customs regulations for your destination regarding antibiotics.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: This medicine starts working within 1 to 2 hours, but you may not notice improvement in symptoms for 24 to 48 hours. Complete the full course as prescribed.
A: Yes, you can take this medicine with or without food. If it upsets your stomach, take it with a meal or snack. However, avoid taking it with dairy products or antacids, as they can reduce absorption.
A: If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double dose.
A: This medicine is generally not recommended during pregnancy unless the doctor determines it is essential. Consult your doctor for safer alternatives.
A: It is best to avoid alcohol while taking this medicine, as it can increase dizziness, drowsiness, and stomach upset.
🤔 Common Patient Concerns
🔄 Substitutes for juflox 300mg tablet
View AllAlternative brands with exact same active ingredient:
-
o cebran 300mg tabletBlue Cross Laboratories Ltd ₹35.00 45.9% CHEAPER
-
zocin 300mg tabletWinsome Laboratories Pvt Ltd ₹40.38 37.6% CHEAPER
-
gyrofix 300mg tabletTotal Healthcare ₹48.00 25.8% CHEAPER
-
offin 300mg tabletBoffin Biotech Pvt Ltd ₹55.97 13.5% CHEAPER
-
ofvas 300mg tabletDecisive Pharma ₹56.25 13% CHEAPER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can cure viral infections like the common cold.
Fact: This medicine is an antibiotic and is only effective against bacterial infections. It does not work against viruses. - Myth: You can stop taking this medicine as soon as you feel better.
Fact: You must complete the full course as prescribed, even if you feel better, to prevent the infection from returning and to reduce antibiotic resistance. - Myth: This medicine is safe for children.
Fact: This medicine is generally not recommended for children under 18 years due to the risk of joint and tendon damage. - Myth: You can take this medicine with milk or antacids.
Fact: Milk, antacids, and mineral supplements can reduce the absorption of this medicine. Separate them by at least 2 hours.
🔄 Alternative Options
Generic Alternatives
- Ofloxacin 300 mg tablet
Brand Alternatives
- Ofloxacin 300 mg tablet (various manufacturers)