Flavospas O 200 mg/200 mg Tablet: Complete Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Sudden tendon pain, swelling, or inability to move a joint
- Numbness, tingling, or weakness in hands or feet
- Severe or bloody diarrhea
- Rash, hives, or swelling of face, lips, or throat
- Palpitations, fainting, or irregular heartbeat
- Yellowing of skin or eyes, dark urine
- Inability to urinate
If experiencing severe symptoms, call emergency services immediately.
What is joxate o 200 mg/200 mg tablet used for?
This medicine is a combination of Ofloxacin (an antibiotic) and Flavoxate (a urinary antispasmodic) used to treat bacterial urinary tract infections accompanied by bladder spasms, urgency, and pain. It is taken orally, usually twice daily, and the full course must be completed as prescribed.
- Generic Name: Ofloxacin (200mg) + Flavoxate (200mg)
- Manufacturer: Dr. Johns Laboratories Pvt Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 joxate o 200 mg/200 mg tablet के बारे में (Hindi Summary)
उपयोग: यह दवा ऑफ़्लोक्सासिन और फ्लेवोक्सेट का संयोजन है। इसका उपयोग मूत्र मार्ग के संक्रमण (यूटीआई) के इलाज के लिए किया जाता है, जिसमें मूत्राशय में ऐंठन, बार-बार पेशाब आना, जलन और दर्द जैसे लक्षण होते हैं। ऑफ़्लोक्सासिन बैक्टीरिया को मारता है और फ्लेवोक्सेट मूत्राशय की मांसपेशियों को आराम देता है। यह दवा डॉक्टर के पर्चे पर ही लेनी चाहिए और पूरा कोर्स पूरा करना चाहिए।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में मतली, उल्टी, पेट दर्द, दस्त, सिरदर्द, चक्कर आना, मुँह सूखना और धुंधली दृष्टि शामिल हैं। कुछ मामलों में त्वचा पर रैश, सूरज की रोशनी से एलर्जी, टेंडन में दर्द या टूटना, और तंत्रिका संबंधी समस्याएँ हो सकती हैं। कोई भी गंभीर लक्षण होने पर तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। इसे पानी के साथ निगलें, चबाएँ नहीं। एंटासिड, आयरन या जिंक सप्लीमेंट के साथ लेने से बचें; कम से कम 2 घंटे का अंतर रखें। पर्याप्त पानी पिएँ। धूप में जाने से बचें और सनस्क्रीन का उपयोग करें। शराब न पिएँ। चक्कर आने पर वाहन न चलाएँ। पूरा कोर्स पूरा करें।
💊 joxate o 200 mg/200 mg tablet Uses & Benefits
[{"condition":"Urinary tract infection with bladder spasms","description":"Used to treat bacterial urinary tract infections while relieving associated bladder spasm, urgency, and frequency.","evidence":"Well-established for the combination in appropriate clinical settings."},{"condition":"Cystitis with dysuria","description":"Helps eradicate causative bacteria and reduces painful urination caused by bladder muscle spasm.","evidence":"Well-established when bacterial infection is confirmed or suspected."},{"condition":"Urethritis with irritative symptoms","description":"May be used when bacterial urethritis is accompanied by significant irritative lower urinary tract symptoms.","evidence":"Limited to specific clinical scenarios; not first-line for all urethritis."}]
Off-label uses: [{"condition":"Prostatitis with voiding symptoms","description":"Occasionally used when bacterial prostatitis is associated with significant bladder outlet spasm, though evidence is limited.","evidence":"Limited"}]
Primary treatment for: Urinary tract infection with bladder spasms
Also treats: Cystitis, Urethritis, Prostatitis
📋 Drug Information
| Generic Name(s) | Ofloxacin (200mg) + Flavoxate (200mg) |
| Brand Name | joxate o 200 mg/200 mg tablet |
| Manufacturer | Dr. Johns Laboratories Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | ANTI INFECTIVES |
| Action Class | |
| Route of Administration | Oral |
| Storage | Store at room temperature between 15°C and 30°C. Protect from light and moisture. Keep out of reach of children. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine combines two active ingredients with distinct mechanisms. Ofloxacin is a fluoroquinolone antibiotic that inhibits bacterial DNA gyrase and topoisomerase IV, enzymes required for DNA replication, transcription, repair, and recombination, leading to bacterial cell death. Flavoxate is a smooth muscle relaxant that acts primarily on the urinary tract; it has anticholinergic and calcium-channel blocking-like effects that reduce smooth muscle contractions in the bladder and urethra, thereby decreasing spasms and associated pain.
Mechanism Steps
💡 How to Take joxate o 200 mg/200 mg tablet
Strength: Each tablet contains Ofloxacin 200 mg and Flavoxate 200 mg.
Dosage Information
| Adult Dosage | The usual adult dose is one tablet taken orally twice daily, or as prescribed by your doctor. The exact dose and duration depend on the type and severity of infection, your kidney and liver function, and your response to treatment. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Do not self-adjust the dose. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients may require dose adjustment based on renal function. Use with caution due to increased risk of tendon rupture, CNS effects, and QT prolongation. Dose must be individualized by a qualified clinician. |
| Renal Impairment | Dose adjustment is required in patients with renal impairment. Ofloxacin clearance is reduced in renal insufficiency. Consult your doctor for appropriate dose modification based on creatinine clearance. |
| Hepatic Impairment | No specific dose adjustment is established for mild to moderate hepatic impairment. Use with caution in severe hepatic impairment. Consult your doctor. |
| Maximum Daily Dose | The maximum recommended daily dose is 400 mg of Ofloxacin and 400 mg of Flavoxate, but the exact maximum must be determined by a qualified clinician based on individual factors. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of joxate o 200 mg/200 mg tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | |
| Antacids | Major | |
| Amiodarone | Major | |
| Theophylline | Major | |
| NSAIDs | Moderate | |
| Corticosteroids | Moderate | |
| Oral hypoglycemics | Moderate | |
| Anticholinergics | Moderate | |
| Probenecid | Minor | |
| Nitrofurantoin | Minor |
🚨 Major Interactions
- Antacids, sucralfate, iron, zinc
- Warfarin
- QT-prolonging drugs (e.g., amiodarone, sotalol, some antipsychotics)
- Theophylline
- NSAIDs
⚡ Moderate Interactions
- Caffeine
- Corticosteroids
- Oral hypoglycemics
- Anticholinergic drugs
🍷 Alcohol Interaction
Alcohol may increase the risk of dizziness, drowsiness, and central nervous system effects. It is advisable to avoid alcohol while taking this medicine.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Known hypersensitivity to Ofloxacin, other fluoroquinolones, or Flavoxate","History of tendon disorders associated with fluoroquinolone use","Myasthenia gravis","Pregnancy and breastfeeding","Children and adolescents (except when specifically indicated)","Severe renal impairment without dose adjustment","Patients with known QT prolongation or uncorrected hypokalemia"]
⚠️ Warnings & Precautions
["Fluoroquinolones can cause disabling and potentially irreversible serious adverse reactions including tendinitis, tendon rupture, peripheral neuropathy, and CNS effects.","Avoid use in patients with a history of tendon disorders.","May exacerbate muscle weakness in patients with myasthenia gravis.","Can cause photosensitivity; avoid excessive sun exposure.","May cause dizziness and drowsiness; avoid driving until you know how it affects you.","Use with caution in elderly patients and those with renal impairment.","May cause blood sugar disturbances; monitor closely in diabetics.","Do not use for viral infections; it is ineffective and promotes resistance."]
🤱 Lactation Safety
Ofloxacin is excreted in breast milk and may cause serious adverse effects in the infant. Flavoxate safety in lactation is not established. Breastfeeding is not recommended while taking this medicine.
💊 Overdose Management
Overdose may cause nausea, vomiting, dizziness, and potentially seizures or QT prolongation. Seek immediate medical attention. Treatment is supportive and symptomatic. Hemodialysis may be considered for Ofloxacin removal in severe cases.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up.
Additional Safety Advice
Take this medicine exactly as prescribed by your doctor. Do not crush, chew, or break the tablet unless instructed. Swallow it whole with a full glass of water. Take it with food if it upsets your stomach. Avoid taking antacids, sucralfate, or iron or zinc supplements within 2 hours before or after this medicine, as they can reduce absorption of Ofloxacin. Stay well hydrated. Avoid excessive sunlight and use sunscreen. Do not drive or operate heavy machinery if you feel dizzy or drowsy. Avoid alcohol while taking this medicine. Inform your doctor if you have kidney or liver problems, diabetes, epilepsy, or a history of tendon problems. Do not share this medicine with others. Complete the full course even if you feel better after a few days.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients are at higher risk of tendon rupture, CNS effects, and QT prolongation. Dose adjustment based on renal function is often necessary. Monitor closely for dizziness and falls.
🤰 Pregnancy Planning (TTC)
This medicine is not recommended if you are planning pregnancy or are pregnant. Consult your doctor for alternative treatments.
🏥 Post-Surgery Considerations
Use with caution after surgery, especially if you have renal impairment or are on other medications. Consult your surgeon before taking this medicine.
🦷 Dental Procedures
Inform your dentist if you are taking this medicine. It may interact with certain antibiotics or anesthetics used during dental procedures.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Avoid strenuous exercise or heavy lifting while taking this medicine, as it may increase the risk of tendon injury. Light activities like walking are generally safe.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause dizziness, drowsiness, or blurred vision. Avoid driving or operating heavy machinery until you know how it affects you. Take rest if needed.
🛑 When to Stop This Medicine
Do not stop this medicine without consulting your doctor. Complete the full prescribed course even if you feel better. If you experience serious side effects, contact your doctor immediately for guidance.
📅 Long-Term Use Effects
Long-term use of this medicine is not recommended unless specifically directed by a doctor. Prolonged use of Ofloxacin can lead to bacterial resistance, fungal overgrowth, and rare but serious effects such as tendon damage, neuropathy, and liver or kidney issues. Regular monitoring may be required if extended therapy is necessary.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Helps flush out bacteria and reduces bladder irritation.
Evidence: Well-establishedMay help prevent urinary tract infections but not treat active infection.
Evidence: LimitedCan help restore gut flora during and after antibiotic therapy.
Evidence: Moderate💉 Vaccination Considerations
💉 If You're Getting Vaccinated
No specific vaccine interactions are established. However, live vaccines should be avoided during antibiotic therapy unless approved by your doctor.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
Carry this medicine in its original packaging with a copy of your prescription. Store at room temperature and protect from moisture. If traveling across time zones, adjust dosing intervals as advised by your doctor. Declare it at customs if required. Do not pack it in checked luggage; keep it in your carry-on bag.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: Symptom relief may begin within a few hours to a day, but the full antibacterial effect takes 2-3 days. Complete the full course as prescribed.
A: Yes, taking it with food reduces stomach upset. However, avoid dairy products within 2 hours of the dose.
A: It is not recommended during pregnancy unless clearly needed. Consult your obstetrician.
A: Take it as soon as you remember if less than half the interval has passed; otherwise skip it. Do not double dose.
🤔 Common Patient Concerns
🔄 Substitutes for joxate o 200 mg/200 mg tablet
View AllAlternative brands with exact same active ingredient:
-
uroconkit 200 mg/200 mg tabletAr-Ex Laboratories Pvt Ltd ₹32.05 79.7% CHEAPER
-
flavocute o 200mg/200mg tabletAlgen Healthcare Limited ₹89.00 43.7% CHEAPER
-
flavospas d 200 mg/200 mg tabletTorrent Pharmaceuticals Ltd ₹109.52 30.7% CHEAPER
-
azoflox uti tabletMac Millon Pharmaceuticals Pvt Ltd ₹135.00 14.5% CHEAPER
-
ophar f 200mg/200mg tabletBiophar Lifesciences Pvt Ltd ₹135.00 14.5% CHEAPER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can cure any urinary problem.
Fact: It is only effective for bacterial infections with associated spasms. It does not treat viral, fungal, or non-infectious urinary conditions. - Myth: I can stop taking it once I feel better.
Fact: You must complete the full prescribed course to prevent bacterial resistance and recurrence. - Myth: It is safe to take with antacids.
Fact: Antacids reduce the absorption of Ofloxacin. Separate by at least 2 hours.
🔄 Alternative Options
Generic Alternatives
- Ofloxacin 200 mg + Flavoxate 200 mg tablet (generic)
Brand Alternatives
- Flavospas O 200 mg/200 mg tablet