jefixi 100mg tablet - Cefixime (100mg) + Lactobacillus (20Million spores) medicine

Jefixi 100mg Tablet: Complete Information

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🏭 Jayson Pharmaceuticals Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Sep 26, 2026
⚠️ Nephrotoxicity Risk 📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Well-established for approved indications.
Reviewed by
SaathiMed Expert Panel | Sep 26, 2026
🩺
Medically Fact-Checked & Clinically Verified by SaathiMed Clinical Review Board
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026

When to Call Your Doctor IMMEDIATELY

  • Blood in stool or vomit
  • Severe abdominal pain
  • Chest pain or difficulty breathing
  • Severe headache with visual changes
  • Sudden swelling of face, lips, or throat
  • Yellowing of skin or eyes
  • Decreased urine output

If experiencing severe symptoms, call emergency services immediately.

What is jefixi 100mg tablet used for?

This medicine is a combination of cefixime, an antibiotic, and lactobacillus, a probiotic. It is used to treat bacterial infections while helping maintain gut health.

  • Generic Name: Cefixime (100mg) + Lactobacillus (20Million spores)
  • Manufacturer: Jayson Pharmaceuticals Ltd
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 jefixi 100mg tablet के बारे में (Hindi Summary)

उपयोग: यह दवा सेफिक्सिम और लैक्टोबैसिलस का संयोजन है, जिसका उपयोग बैक्टीरियल संक्रमणों जैसे श्वसन तंत्र, मूत्र मार्ग और कान के संक्रमण के इलाज के लिए किया जाता है। यह आंतों के स्वस्थ बैक्टीरिया को बनाए रखने में भी मदद करती है।

साइड इफेक्ट्स: आम दुष्प्रभावों में दस्त, मतली, पेट दर्द और सिरदर्द शामिल हैं। गंभीर दुष्प्रभाव दुर्लभ हैं लेकिन एलर्जी, गंभीर दस्त या गुर्दे की समस्या हो सकती है। किसी भी गंभीर लक्षण पर तुरंत डॉक्टर से संपर्क करें।

सुरक्षा सलाह: इस दवा को डॉक्टर के निर्देशानुसार ही लें। पूरा कोर्स पूरा करें, बीच में न छोड़ें। खाने के साथ लें ताकि पेट खराब न हो। अगर खुराक भूल जाएं तो याद आते ही लें, लेकिन अगली खुराक का समय नजदीक हो तो छोड़ दें। डबल डोज न लें। शराब से बचें। एलर्जी के लक्षण दिखने पर तुरंत डॉक्टर से मिलें।

💡 Did You Know? The Indian pharmaceutical market is expected to reach $130 billion by 2030.

💊 jefixi 100mg tablet Uses & Benefits

[{"condition":"Respiratory tract infections","description":"Used to treat infections of the throat, tonsils, sinuses, and lungs caused by susceptible bacteria.","evidence":"Well-established"},{"condition":"Urinary tract infections","description":"Effective against bacterial infections of the bladder and kidneys.","evidence":"Well-established"},{"condition":"Ear infections","description":"Treats middle ear infections caused by susceptible bacteria.","evidence":"Well-established"},{"condition":"Gonorrhea","description":"Used as a single-dose treatment for uncomplicated gonorrhea.","evidence":"Well-established"}]

Off-label uses: []

Primary treatment for: Bacterial infections

Also treats: Respiratory tract infections, Urinary tract infections, Ear infections, Gonorrhea

📋 Drug Information

Generic Name(s)Cefixime (100mg) + Lactobacillus (20Million spores)
Brand Namejefixi 100mg tablet
ManufacturerJayson Pharmaceuticals Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassANTI INFECTIVES
Action Class
Route of AdministrationOral
StorageStore at room temperature (15-30°C) in a dry place, away from direct sunlight.
Shelf Life24 months from the date of manufacture.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Take this medicine with food to reduce stomach upset.
2
Complete the full course even if you feel better after a few days.
3
Stay well hydrated throughout the day.
4
Avoid alcohol while taking this medicine.
5
Do not take more than the prescribed dose.
6
Consult your doctor if symptoms persist beyond 7 days.
7
Report any unusual bleeding or bruising immediately.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅
Fever with cough
This medicine may be prescribed for respiratory infections.
Likely Use
✅
Burning urination
This medicine is used for urinary tract infections.
Likely Use
❌
Common cold
This medicine is not effective against viral infections.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionCefixime is absorbed from the gastrointestinal tract, with a bioavailability of approximately 40-50% after oral administration. Food does not significantly affect absorption.
DistributionCefixime distributes widely into body tissues and fluids, including the respiratory tract, urine, and bile. It does not penetrate the cerebrospinal fluid well.
Protein BindingCefixime is approximately 65% bound to plasma proteins.
MetabolismCefixime is not significantly metabolized in the body.
Half-LifeThe elimination half-life of cefixime is approximately 3-4 hours in healthy adults.
ExcretionCefixime is primarily excreted unchanged in the urine.
BioavailabilityApproximately 40-50%.
Onset of ActionThe onset of action is typically within 1-2 hours after oral administration.
Peak Plasma TimePeak plasma concentrations are reached 2-4 hours after oral administration.
Duration of ActionThe duration of action is typically 12-24 hours, depending on the dose and susceptibility of the bacteria.

How It Works

Cefixime is a third-generation cephalosporin antibiotic that works by inhibiting bacterial cell wall synthesis. It binds to penicillin-binding proteins, disrupting the cross-linking of peptidoglycan, which leads to bacterial cell death. Lactobacillus is a probiotic that helps restore and maintain beneficial gut flora, which may be disrupted by antibiotic therapy.

Mechanism Steps

1
Binding to penicillin-binding proteins: Cefixime binds to specific penicillin-binding proteins on the bacterial cell wall.
2
Inhibition of cell wall synthesis: This binding inhibits the transpeptidation step in peptidoglycan synthesis, weakening the cell wall.
3
Bacterial cell lysis: The weakened cell wall leads to osmotic lysis and death of the bacteria.
4
Probiotic effect: Lactobacillus colonizes the gut and helps restore beneficial bacteria that may be killed by the antibiotic.

💡 How to Take jefixi 100mg tablet

Strength: Tablet containing Cefixime 100 mg and Lactobacillus 20 million spores.

1Take this medicine orally with a full glass of water.
2Take it with food to reduce stomach upset.
3Swallow the tablet whole; do not crush or chew.
4Take at evenly spaced intervals as prescribed.
5Complete the full course even if you feel better.

Dosage Information

Adult DosageThe usual adult dose of this medicine is 200-400 mg of cefixime daily, taken as a single dose or in two divided doses, depending on the type and severity of the infection. The lactobacillus component is typically 20 million spores per dose. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageElderly patients may require dose adjustment based on renal function. Consult a doctor.
Renal ImpairmentIn patients with renal impairment, dose adjustment is required. For creatinine clearance less than 20 mL/min, a reduced dose is recommended. Consult a doctor.
Hepatic ImpairmentNo specific dose adjustment is required for hepatic impairment, but caution is advised.
Maximum Daily DoseThe maximum recommended daily dose is 400 mg of cefixime.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With food
Take with meals
Reduces stomach upset.
Alcohol
Avoid
May increase side effects like dizziness and nausea.

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of jefixi 100mg tablet

✅ Common Side Effects

Diarrhea (Common (5-10%))
Usually resolves on its own. Stay hydrated. Consult doctor if persistent.
Nausea (Common (5-10%))
Take with food to reduce nausea. Consult doctor if severe.
Abdominal pain (Common (5-10%))
Take with food. Consult doctor if severe or persistent.
Headache (Common (5-10%))
Usually resolves. Consult doctor if persistent.

🚨 Serious Side Effects

Severe allergic reaction (anaphylaxis) (Rare (<0.1%))
Seek immediate medical attention if you experience rash, swelling, difficulty breathing, or dizziness.
Clostridioides difficile-associated diarrhea (Rare (<0.1%))
Seek immediate medical attention if you develop severe or persistent diarrhea, abdominal pain, or fever.
Kidney problems (Rare (<0.1%))
Report decreased urine output or swelling to your doctor immediately.

⚠️ Rare Side Effects

Seizures
Seek immediate medical attention.
Blood disorders
Report unusual bleeding or bruising to your doctor.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Warfarin Major
Carbamazepine Major
Probenecid Moderate
Oral contraceptives Moderate
Antacids Minor

🚨 Major Interactions

  • Warfarin
  • Carbamazepine

⚡ Moderate Interactions

  • Probenecid
  • Oral contraceptives

🍷 Alcohol Interaction

Alcohol may increase the risk of stomach upset and dizziness. It is advisable to avoid alcohol while taking this medicine.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Known allergy to cephalosporin antibiotics","History of severe allergic reaction to penicillin","Severe renal impairment (dose adjustment required)"]

⚠️ Warnings & Precautions

["Use with caution in patients with renal impairment.","May cause Clostridioides difficile-associated diarrhea.","May reduce the efficacy of oral contraceptives.","Avoid alcohol during treatment.","Complete the full course of therapy as prescribed."]

🤱 Lactation Safety

Cefixime is excreted in breast milk in small amounts and is generally considered safe during breastfeeding. Lactobacillus is safe. Consult your doctor.

💊 Overdose Management

Overdose may cause nausea, vomiting, and diarrhea. Seek immediate medical attention. Treatment is symptomatic and supportive. Hemodialysis may be considered in severe cases.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose.

Additional Safety Advice

General Safety

Take this medicine exactly as prescribed by your doctor. Do not skip doses or stop treatment early, even if you feel better. Complete the full course to ensure the infection is fully treated and to prevent antibiotic resistance. Take this medicine with food to reduce stomach upset. If you miss a dose, take it as soon as you remember, but if it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose. Inform your doctor if you have kidney problems, as dose adjustment may be needed. Avoid alcohol while taking this medicine. If you experience any signs of an allergic reaction, such as rash, swelling, or difficulty breathing, seek immediate medical attention.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients may have reduced kidney function and may require dose adjustment. Monitor for side effects closely.

🤰 Pregnancy Planning (TTC)

If you are planning pregnancy, consult your doctor before taking this medicine. It is generally considered safe but use only if clearly needed.

🏥 Post-Surgery Considerations

Inform your surgeon if you are taking this medicine before surgery. It may interact with other medications used during surgery.

🦷 Dental Procedures

Inform your dentist if you are taking this medicine. It may affect the choice of antibiotics for dental procedures.

💚 Lifestyle Tips for Better Results

🏃
Maintain a healthy diet rich in fiber to support gut health.
🥗
Stay hydrated by drinking plenty of water.
😴
Get adequate rest to help your body fight infection.
💧
Practice good hygiene to prevent reinfection.
🧘
Avoid sharing personal items like towels and utensils.

🏋️ Exercise Considerations

Moderate exercise is generally safe, but if you feel weak or dizzy, take rest. Avoid strenuous activities until you recover.

🥗 Diet Recommendations

Include probiotic-rich foods like yogurt to support gut health.
Eat light, easily digestible meals.
Avoid spicy and oily foods that may irritate the stomach.
Stay well hydrated.

💼 Impact on Daily Work & Life

This medicine may cause dizziness or fatigue in some people. If affected, avoid driving or operating heavy machinery until you know how it affects you.

🛑 When to Stop This Medicine

Do not stop this medicine without consulting your doctor. Complete the full course as prescribed, even if you feel better. If you experience severe side effects, contact your doctor immediately.

📅 Long-Term Use Effects

Long-term use of antibiotics can lead to antibiotic resistance and disruption of gut flora. This medicine is usually prescribed for a short duration. Prolonged use should be avoided unless directed by a doctor. Monitor for signs of superinfection.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Probiotics

Can help maintain gut health during antibiotic therapy.

Evidence: Well-established
Symptomatic treatment

For viral infections, rest and fluids are recommended instead of antibiotics.

Evidence: Well-established

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

Antibiotics may reduce the efficacy of live bacterial vaccines like typhoid vaccine. Consult your doctor about timing.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

Carry this medicine in its original packaging with a copy of your prescription. Store at room temperature and protect from direct sunlight. If traveling across time zones, adjust dosing times gradually as advised by your doctor. Check customs regulations for carrying prescription medicines.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 35-year-old woman with a urinary tract infection
She was prescribed this medicine for a UTI. She took it with food as directed and completed the 7-day course. Her symptoms improved within 3 days, and she felt back to normal after finishing the course. She experienced mild diarrhea, which resolved after taking probiotics.
💡 Lesson: Taking the full course and with food improves outcomes and reduces side effects.
👤 A 50-year-old man with a respiratory tract infection
He started this medicine for bronchitis. He initially felt nauseous but switched to taking it with meals, which helped. He completed the 10-day course and his cough and fever resolved. He was advised to avoid alcohol during treatment.
💡 Lesson: Adjusting timing with food can improve tolerability, and avoiding alcohol prevents interactions.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: You may start feeling better within 2-3 days, but it is important to complete the full course as prescribed.

Q: Can I take this medicine with food?

A: Yes, taking it with food helps reduce stomach upset.

Q: What should I do if I miss a dose?

A: Take it as soon as you remember, but if it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my kidney function?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?

🛑 Myths vs. Facts

  • Myth: Antibiotics can cure viral infections like the flu.
    Fact: Antibiotics only work against bacteria, not viruses.
  • Myth: You can stop taking antibiotics once you feel better.
    Fact: You must complete the full course to prevent resistance and ensure cure.

🔄 Alternative Options

Generic Alternatives

  • Cefixime 100 mg + Lactobacillus 20 million spores tablet

📊 Comparison with Similar Medicines

[{"medicine":"This medicine","composition":"Cefixime 100 mg + Lactobacillus 20 million spores","strength":"100 mg","form":"Tablet"},{"medicine":"Cefixime 200 mg + Lactobacillus","composition":"Cefixime 200 mg + Lactobacillus 20 million spores","strength":"200 mg","form":"Tablet"}]

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