Jedacef T 1gm/125mg Injection: Complete Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Difficulty breathing or swelling of face, lips, or throat
- Severe or bloody diarrhea
- Seizures or confusion
- Severe skin rash with blistering or peeling
- Decreased urine output or swelling
- Persistent high fever despite treatment
If experiencing severe symptoms, call emergency services immediately.
What is jedacef t 1gm/125mg injection used for?
This medicine is a combination antibiotic injection containing ceftazidime and tazobactam. It is used to treat serious bacterial infections. It works by killing bacteria and is administered by a healthcare professional.
- Generic Name: Ceftazidime (1gm) + Tazobactum (125mg)
- Manufacturer: Apus Life Pvt Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 jedacef t 1gm/125mg injection के बारे में (Hindi Summary)
उपयोग: यह दवा सेफ्टाज़िडाइम और टैज़ोबैक्टम का संयोजन है, जिसका उपयोग गंभीर जीवाणु संक्रमणों के इलाज के लिए किया जाता है। यह अस्पताल में डॉक्टर द्वारा इंजेक्शन के रूप में दी जाती है। यह मूत्र मार्ग संक्रमण, निमोनिया, त्वचा संक्रमण और पेट के संक्रमण में प्रभावी है। यह वायरल संक्रमण जैसे सर्दी-जुकाम के लिए नहीं है।
साइड इफेक्ट्स: आम दुष्प्रभावों में इंजेक्शन स्थल पर दर्द, दस्त, मतली, उल्टी, सिरदर्द और दाने शामिल हैं। गंभीर दुष्प्रभाव दुर्लभ हैं लेकिन एलर्जी, गंभीर दस्त, दौरे और रक्त विकार हो सकते हैं। किसी भी असामान्य लक्षण की सूचना तुरंत डॉक्टर को दें।
सुरक्षा सलाह: यह दवा केवल डॉक्टर की देखरेख में दी जानी चाहिए। अपनी सभी एलर्जी और दवाओं के बारे में डॉक्टर को बताएं। गुर्दे या यकृत की बीमारी हो तो सावधानी बरतें। इलाज के दौरान शराब न पिएं। पूरा कोर्स पूरा करें। गंभीर दस्त, दाने या सांस लेने में कठिनाई हो तो तुरंत डॉक्टर से मिलें।
💊 jedacef t 1gm/125mg injection Uses & Benefits
[{"condition":"Complicated urinary tract infections","description":"Used to treat serious kidney and bladder infections caused by susceptible bacteria.","evidence":"Well-established"},{"condition":"Hospital-acquired pneumonia","description":"Effective against many gram-negative bacteria causing lung infections in hospitalized patients.","evidence":"Well-established"},{"condition":"Skin and soft tissue infections","description":"Treats severe skin infections including cellulitis and abscesses.","evidence":"Well-established"},{"condition":"Intra-abdominal infections","description":"Used in combination with other antibiotics for complicated abdominal infections.","evidence":"Well-established"},{"condition":"Febrile neutropenia","description":"Empiric therapy for fever in patients with low white blood cell counts.","evidence":"Well-established"}]
Off-label uses: [{"condition":"Melioidosis","description":"Sometimes used for treatment of Burkholderia pseudomallei infections.","evidence":"Limited"},{"condition":"Cystic fibrosis exacerbations","description":"May be used for pulmonary exacerbations in cystic fibrosis patients.","evidence":"Limited"}]
Primary treatment for: Bacterial infections
Also treats: Complicated urinary tract infections, Hospital-acquired pneumonia, Skin and soft tissue infections, Intra-abdominal infections, Febrile neutropenia
📋 Drug Information
| Generic Name(s) | Ceftazidime (1gm) + Tazobactum (125mg) |
| Brand Name | jedacef t 1gm/125mg injection |
| Manufacturer | Apus Life Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | ANTI INFECTIVES |
| Action Class | |
| Route of Administration | Parenteral (intravenous or intramuscular) |
| Storage | Store the unreconstituted powder at room temperature (20-25°C). After reconstitution, the solution should be used within the time specified by the manufacturer, typically within 24 hours if refrigerated. Protect from light. |
| Shelf Life | Typically 24 months from the date of manufacture. Refer to the product label for the exact expiry date. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
Ceftazidime inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins, leading to bacterial death. Tazobactam irreversibly inhibits certain beta-lactamase enzymes, protecting ceftazidime from degradation and extending its spectrum against beta-lactamase-producing bacteria.
Mechanism Steps
💡 How to Take jedacef t 1gm/125mg injection
Strength: Injection: Ceftazidime 1 gram + Tazobactam 125 milligrams per vial.
Dosage Information
| Adult Dosage | The usual adult dose is 1 gram of ceftazidime plus 125 milligrams of tazobactam administered intravenously every 8 hours. For severe infections, the dose may be increased to 2 grams every 8 hours. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients may have reduced renal function; dose should be adjusted based on creatinine clearance. Use with caution and monitor renal function. |
| Renal Impairment | Dose adjustment is required in patients with renal impairment. For creatinine clearance 31-50 mL/min, administer 1 gram every 12 hours. For 16-30 mL/min, administer 1 gram every 24 hours. For 6-15 mL/min, administer 500 mg every 24 hours. For <5 mL/min, administer 500 mg every 48 hours. Consult a clinician for precise dosing. |
| Hepatic Impairment | No specific dose adjustment is recommended for hepatic impairment alone. However, monitor liver function. |
| Maximum Daily Dose | The maximum recommended daily dose is 6 grams of ceftazidime (e.g., 2 grams every 8 hours) in adults with normal renal function. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of jedacef t 1gm/125mg injection
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Gentamicin | Major | |
| Furosemide | Major | |
| Warfarin | Moderate | |
| Probenecid | Moderate | |
| Chloramphenicol | Moderate | |
| Oral contraceptives | Minor |
🚨 Major Interactions
- Aminoglycosides (e.g., gentamicin)
- Loop diuretics (e.g., furosemide)
- Warfarin
⚡ Moderate Interactions
- Probenecid
- Chloramphenicol
🍷 Alcohol Interaction
Avoid alcohol while receiving this medicine as it may worsen side effects and hinder recovery from infection.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Known severe hypersensitivity to ceftazidime, tazobactam, or other beta-lactam antibiotics","Previous anaphylactic reaction to penicillins or cephalosporins"]
⚠️ Warnings & Precautions
["Serious hypersensitivity reactions, including anaphylaxis, can occur.","Clostridioides difficile-associated diarrhea may develop.","Use with caution in patients with renal impairment; dose adjustment required.","May cause seizures, especially in patients with renal impairment.","Prolonged use may lead to overgrowth of non-susceptible organisms.","Monitor for superinfections.","Use with caution in patients with a history of gastrointestinal disease, especially colitis."]
🤱 Lactation Safety
Ceftazidime is excreted in human milk in low concentrations. Tazobactam is also excreted in milk. Consult your doctor before breastfeeding while on this medicine.
💊 Overdose Management
Overdose may cause nausea, vomiting, and seizures. Treatment is supportive and symptomatic. Hemodialysis may be considered to remove ceftazidime from the blood in severe cases. Contact a poison control center or emergency department immediately.
⏰ Missed Dose
Since this medicine is administered by a healthcare professional, missed doses are unlikely. If a dose is missed, contact your healthcare provider for guidance. Do not attempt to self-administer.
Additional Safety Advice
This medicine must be given only under medical supervision. Inform your doctor about any allergies to antibiotics, especially penicillins or cephalosporins. Tell your doctor if you have kidney disease, liver disease, or a history of seizures. Do not breastfeed while receiving this medicine without consulting your doctor. Avoid alcohol during treatment. Complete the full course as prescribed, even if you feel better. Report any severe diarrhea, rash, or difficulty breathing immediately.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients are at higher risk of renal impairment and should have doses adjusted accordingly. Monitor closely for side effects.
🤰 Pregnancy Planning (TTC)
Consult your doctor if you are planning pregnancy or are pregnant. This medicine should be used only if clearly needed.
🏥 Post-Surgery Considerations
This medicine may be used to prevent or treat surgical site infections. Follow your surgeon's instructions.
🦷 Dental Procedures
Inform your dentist if you are on this medicine. It may be used prophylactically for dental procedures in certain heart conditions.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Avoid strenuous exercise while recovering from a serious infection. Gradually resume activities as you feel better.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
You may need to take time off work during treatment, especially if hospitalized. Avoid driving if you feel dizzy or weak.
🛑 When to Stop This Medicine
Do not stop this medicine without consulting your doctor. Complete the full course as prescribed, even if you feel better.
📅 Long-Term Use Effects
Long-term use may lead to antibiotic resistance and superinfections. Prolonged use requires monitoring of renal and liver function. Use only for the prescribed duration.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Depending on the infection and susceptibility, other antibiotics may be used.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
No specific vaccine interactions are established. However, inform your doctor about recent vaccinations.
📦 Storage Guide
✅ DO
Store at room temperature (20-25°C)
❌ DON'T
Do not freeze
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Protect from light
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
Carry this medicine in its original packaging with a copy of the prescription. Since it is an injectable, it is usually administered in a healthcare setting. If traveling, ensure proper storage at room temperature and protect from light. Check customs regulations for carrying injectable antibiotics.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: Improvement is usually seen within 2-3 days, but the full course must be completed.
A: No, it must be administered by a healthcare professional.
🤔 Common Patient Concerns
🔄 Substitutes for jedacef t 1gm/125mg injection
View AllAlternative brands with exact same active ingredient:
-
magnazide tz 1gm/125mg injectionIkon Remedies Pvt Ltd ₹349.00 4.5% CHEAPER
-
omnazide tz 1gm/125mg injectionInnovative Pharmaceuticals ₹349.00 4.5% CHEAPER
-
Trazim-TM 1.125gm InjectionAster Pharma ₹450.00 23.1% COSTLIER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can cure viral infections.
Fact: This medicine is an antibiotic and is only effective against bacterial infections. - Myth: You can stop taking this medicine once you feel better.
Fact: You must complete the full course as prescribed to prevent recurrence and resistance.
🔄 Alternative Options
Generic Alternatives
- Ceftazidime + Tazobactam injection
Brand Alternatives
- Jedacef T 1gm/125mg Injection