Atfour 80mg Tablet: Complete Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Unexplained muscle pain, tenderness, or weakness, especially with fever or dark urine.
- Yellowing of the skin or eyes (jaundice).
- Severe abdominal pain, nausea, or vomiting.
- Dark urine or decreased urine output.
- Swelling of the face, lips, tongue, or throat, or difficulty breathing.
- Severe headache with visual changes.
- Chest pain or shortness of breath.
- Unusual bleeding or bruising.
If experiencing severe symptoms, call emergency services immediately.
What is itor 80mg tablet used for?
This medicine is a statin used to lower cholesterol and reduce the risk of heart attack and stroke. It works by blocking an enzyme in the liver that produces cholesterol. It is taken orally once daily, with or without food, and requires regular monitoring of liver function and lipid levels.
- Generic Name: Atorvastatin (80mg)
- Manufacturer: Isis Healthcare Pvt Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 itor 80mg tablet के बारे में (Hindi Summary)
उपयोग: यह दवा एटोरवास्टेटिन 80 मिलीग्राम टैबलेट के रूप में उपलब्ध है और मुख्य रूप से उच्च कोलेस्ट्रॉल के इलाज के लिए इस्तेमाल की जाती है। यह खून में खराब कोलेस्ट्रॉल (एलडीएल) और ट्राइग्लिसराइड्स को कम करने में मदद करती है। इसके अलावा, यह दिल के दौरे, स्ट्रोक और अन्य हृदय संबंधी समस्याओं के जोखिम को कम करने के लिए भी दी जाती है, खासकर उन लोगों में जिन्हें पहले से दिल की बीमारी है या जिनमें कई जोखिम कारक मौजूद हैं। यह दवा लीवर में एक एंजाइम को रोककर काम करती है जो कोलेस्ट्रॉल बनाता है, जिससे खून में कोलेस्ट्रॉल का स्तर कम हो जाता है। यह दवा डॉक्टर के पर्चे के बिना नहीं लेनी चाहिए और इसे स्वस्थ आहार और नियमित व्यायाम के साथ लेना चाहिए।
साइड इफेक्ट्स: इस दवा के कुछ सामान्य दुष्प्रभाव हो सकते हैं जैसे सिरदर्द, मतली, दस्त, कब्ज और मांसपेशियों में दर्द। ये आमतौर पर हल्के होते हैं और कुछ समय में ठीक हो जाते हैं। लेकिन कुछ गंभीर दुष्प्रभाव भी हो सकते हैं, जिनमें मांसपेशियों में असहनीय दर्द, कमजोरी, बुखार, गहरे रंग का पेशाब, पीलिया (आंखों और त्वचा का पीला पड़ना), पेट दर्द, और एलर्जी प्रतिक्रियाएं जैसे चकत्ते, खुजली, चेहरे, होंठ या गले में सूजन शामिल हैं। अगर आपको इनमें से कोई भी लक्षण दिखे तो तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: इस दवा को शुरू करने से पहले अपने डॉक्टर को अपनी सभी स्वास्थ्य स्थितियों के बारे में बताएं, खासकर लीवर या किडनी की बीमारी, डायबिटीज, और थायरॉइड की समस्या। अपनी सभी दवाओं, सप्लीमेंट्स और हर्बल उत्पादों के बारे में भी जानकारी दें। अगर आप गर्भवती हैं, गर्भधारण की योजना बना रही हैं या स्तनपान करा रही हैं, तो यह दवा न लें। ग्रेपफ्रूट या इसके जूस का सेवन न करें क्योंकि इससे दवा का स्तर बढ़ सकता है और दुष्प्रभावों का खतरा हो सकता है। शराब का सेवन सीमित करें या बिल्कुल न करें। अपने डॉक्टर की सलाह के बिना यह दवा बंद न करें, भले ही आप बेहतर महसूस करें। नियमित रूप से लीवर फंक्शन और कोलेस्ट्रॉल की जांच कराते रहें।
💊 itor 80mg tablet Uses & Benefits
[{"condition":"Hypercholesterolemia","description":"This medicine is used to reduce elevated total cholesterol, LDL cholesterol, and triglycerides in patients with primary hypercholesterolemia.","evidence":"Well-established"},{"condition":"Mixed Dyslipidemia","description":"It is effective in treating mixed dyslipidemia, characterized by high LDL cholesterol and high triglycerides.","evidence":"Well-established"},{"condition":"Cardiovascular Risk Reduction","description":"This medicine is prescribed to reduce the risk of heart attack, stroke, and revascularization procedures in patients with multiple cardiovascular risk factors.","evidence":"Well-established"},{"condition":"Familial Hypercholesterolemia","description":"It is used as an adjunct to diet in patients with heterozygous and homozygous familial hypercholesterolemia.","evidence":"Well-established"}]
Off-label uses: [{"condition":"Non-alcoholic Fatty Liver Disease","description":"Sometimes prescribed off-label to improve liver enzyme levels in patients with non-alcoholic fatty liver disease.","evidence":"Limited"},{"condition":"Chronic Kidney Disease","description":"May be used off-label to slow the progression of kidney disease in some patients.","evidence":"Limited"}]
Primary treatment for: Hypercholesterolemia
Also treats: Mixed dyslipidemia, Cardiovascular risk reduction, Familial hypercholesterolemia
📋 Drug Information
| Generic Name(s) | Atorvastatin (80mg) |
| Brand Name | itor 80mg tablet |
| Manufacturer | Isis Healthcare Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | CARDIAC |
| Action Class | HMG CoA inhibitors (statins) |
| Route of Administration | Oral |
| Storage | Store at room temperature between 20°C and 25°C (68°F to 77°F). Keep away from moisture and heat. Store in the original container. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | The World Health Organization recommends statins, including atorvastatin, for the prevention of cardiovascular disease in patients at high risk. However, specific recommendations should be based on individual patient assessment and local guidelines. |
| ICMR Guideline | The Indian Council of Medical Research (ICMR) guidelines recommend statins for primary and secondary prevention of cardiovascular disease in appropriate patients. Atorvastatin is commonly used in India for the management of dyslipidemia. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine works by competitively inhibiting the enzyme HMG-CoA reductase, which is the rate-limiting step in the mevalonate pathway of cholesterol synthesis in the liver. By blocking this enzyme, it reduces the production of cholesterol in the liver, leading to a decrease in intracellular cholesterol levels. This, in turn, triggers an upregulation of LDL receptors on the surface of liver cells, which increases the uptake and clearance of LDL cholesterol from the bloodstream. The overall effect is a significant reduction in total cholesterol, LDL cholesterol, and triglycerides, along with a modest increase in HDL cholesterol. Additionally, this medicine has pleiotropic effects, such as improving endothelial function, reducing inflammation, and stabilizing atherosclerotic plaques, which contribute to its cardiovascular benefits.
Mechanism Steps
💡 How to Take itor 80mg tablet
Strength: Atorvastatin 80 mg immediate-release tablet.
Dosage Information
| Adult Dosage | The usual starting dose of this medicine for adults is 10 to 20 mg once daily, but for this 80 mg strength, it is typically reserved for patients who require intensive LDL cholesterol reduction, such as those with familial hypercholesterolemia or established cardiovascular disease. The dose may be adjusted based on the patient's lipid levels and response to therapy. The maximum recommended dose is 80 mg once daily. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function, and concomitant medications. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | No specific dose adjustment is required for elderly patients based solely on age. However, because elderly patients may have decreased renal or hepatic function or concomitant illnesses, this medicine should be used with caution. Dose must be individualized by a qualified clinician. |
| Renal Impairment | No dose adjustment is required for patients with mild to moderate renal impairment. In patients with severe renal impairment, this medicine should be used with caution and the dose should be individualized by a qualified clinician. |
| Hepatic Impairment | This medicine is contraindicated in patients with active liver disease or unexplained persistent elevations of serum transaminases. In patients with mild to moderate hepatic impairment, the dose should be reduced and used with caution. Dose must be individualized by a qualified clinician. |
| Maximum Daily Dose | 80 mg once daily. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of itor 80mg tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Cyclosporine | Major | |
| Clarithromycin | Major | |
| Itraconazole | Major | |
| Warfarin | Major | |
| Gemfibrozil | Moderate | |
| Grapefruit juice | Moderate | |
| Niacin | Moderate | |
| Digoxin | Moderate | |
| Antacids | Minor | |
| Colchicine | Minor |
🚨 Major Interactions
- Cyclosporine
- Clarithromycin
- Itraconazole
- HIV protease inhibitors
- Warfarin
⚡ Moderate Interactions
- Grapefruit juice
- Fibrates (e.g., gemfibrozil)
- Niacin
- Digoxin
- Oral contraceptives
🍷 Alcohol Interaction
Alcohol can increase the risk of liver damage when taken with this medicine. It is advisable to limit or avoid alcohol consumption while on this medicine, especially if you have a history of liver disease or drink heavily. If you consume alcohol, do so in moderation and inform your doctor.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Active liver disease or unexplained persistent elevations of serum transaminases.","Hypersensitivity to atorvastatin or any component of the formulation.","Pregnancy and breastfeeding.","Concomitant use with strong CYP3A4 inhibitors such as clarithromycin, itraconazole, and HIV protease inhibitors.","Concomitant use with cyclosporine."]
⚠️ Warnings & Precautions
["Muscle effects: This medicine can cause myopathy and, rarely, rhabdomyolysis. Patients should be advised to report unexplained muscle pain, tenderness, or weakness, especially if accompanied by fever or dark urine.","Liver enzyme abnormalities: Liver function tests should be monitored. If persistent elevations occur, discontinuation may be necessary.","Diabetes: This medicine may increase the risk of new-onset diabetes. Monitor blood glucose in at-risk patients.","Endocrine effects: This medicine may affect adrenal and gonadal steroid production. Use with caution in patients with endocrine disorders.","CNS toxicity: Rare cases of memory loss and confusion have been reported. These are usually reversible upon discontinuation.","Immune-mediated necrotizing myopathy: A rare but serious condition that may persist despite discontinuation. Requires immunosuppressive therapy."]
🤱 Lactation Safety
This medicine is excreted in human breast milk. Because of the potential for serious adverse reactions in nursing infants, women should not breastfeed while taking this medicine. Consult your doctor for alternative feeding options.
💊 Overdose Management
There is no specific antidote for overdose with this medicine. In case of overdose, symptomatic and supportive treatment should be initiated. Liver function tests and creatine kinase levels should be monitored. Hemodialysis is not expected to significantly enhance clearance. Contact a poison control center or emergency room immediately if overdose is suspected.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for a missed one.
Additional Safety Advice
Before starting this medicine, inform your doctor about all your medical conditions, especially liver disease, kidney disease, diabetes, or thyroid problems. Also, disclose all other medications, supplements, and herbal products you are taking, as this medicine can interact with many substances. Do not take this medicine if you are pregnant, planning to become pregnant, or breastfeeding. Women of childbearing age should use effective contraception while taking this medicine. Avoid consuming large amounts of grapefruit or grapefruit juice, as it can increase the levels of this medicine in your body and raise the risk of side effects. Limit alcohol consumption, as it can increase the risk of liver problems. Follow a cholesterol-lowering diet and exercise regularly as advised by your doctor. Do not stop taking this medicine without consulting your doctor, even if you feel well, because high cholesterol often has no symptoms. Keep all scheduled appointments for blood tests to monitor your liver function and cholesterol levels.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients may be more sensitive to the effects of this medicine, particularly muscle toxicity. Dose should be individualized based on renal and hepatic function. Regular monitoring of liver function and creatine kinase is recommended. Falls and fractures should be monitored due to potential muscle weakness.
🤰 Pregnancy Planning (TTC)
This medicine is contraindicated during pregnancy and in women planning to become pregnant. If you are planning pregnancy, consult your doctor to discuss alternative treatments for high cholesterol. Effective contraception should be used while taking this medicine.
🏥 Post-Surgery Considerations
This medicine can be continued before and after surgery, but inform your surgeon and anesthesiologist that you are taking it. In some cases, it may be temporarily discontinued if there is a risk of interaction with other medications or if you are unable to take oral medications. Follow your doctor's instructions.
🦷 Dental Procedures
Inform your dentist that you are taking this medicine. There are no specific contraindications for dental procedures, but if you are taking blood thinners like warfarin, your dentist should be aware of the increased bleeding risk. No dose adjustment is typically needed.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
This medicine is not known to limit exercise capacity. However, if you experience muscle pain or weakness, avoid strenuous exercise and consult your doctor. Regular moderate exercise is encouraged as part of a heart-healthy lifestyle.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine is not expected to affect your ability to work or drive. However, if you experience dizziness, vision changes, or muscle weakness, avoid driving or operating heavy machinery until you feel better. Most people can continue their normal activities while taking this medicine.
🛑 When to Stop This Medicine
Do not stop taking this medicine without consulting your doctor. If you experience serious side effects such as severe muscle pain, liver problems, or allergic reactions, contact your doctor immediately. Your doctor may adjust the dose or switch you to another medicine. Stopping suddenly can increase your risk of cardiovascular events.
📅 Long-Term Use Effects
Long-term use of this medicine is generally safe and effective for managing high cholesterol and reducing cardiovascular risk. Regular monitoring of liver function and lipid levels is required. Some patients may experience persistent muscle symptoms or an increased risk of diabetes. The benefits of long-term use typically outweigh the risks in patients with high cardiovascular risk. Periodic review with your doctor is necessary to adjust the dose and monitor for any adverse effects.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
A heart-healthy diet and regular exercise can help lower cholesterol levels naturally.
Evidence: Well-establishedRosuvastatin, simvastatin, and pravastatin are alternative statins that may be used if atorvastatin is not tolerated.
Evidence: Well-establishedEzetimibe, PCSK9 inhibitors, and bile acid sequestrants are options for patients who cannot take statins.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
This medicine does not interact with vaccines. You can receive vaccinations as recommended by your doctor. There is no need to adjust your vaccination schedule while taking this medicine.
📦 Storage Guide
✅ DO
Store at room temperature (20-25°C)
❌ DON'T
Do not refrigerate
✅ DO
Keep in the original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight and moisture
❌ DON'T
Do not store in the bathroom
✅ DO
Keep out of reach of children
❌ DON'T
Do not use after the expiry date
✈️ Traveling with This Medicine
When traveling, carry this medicine in its original packaging with a copy of your prescription. Keep it in your carry-on luggage to avoid loss. Store at room temperature and protect from moisture and heat. If crossing time zones, continue taking your dose at the same local time as usual. Check customs regulations for carrying prescription medicines. Carry enough supply for your entire trip.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: This medicine starts to lower cholesterol within 2 weeks, with maximum effects seen in 4 to 6 weeks.
A: No, you should not stop without consulting your doctor. High cholesterol often has no symptoms, and stopping the medicine can cause cholesterol levels to rise again.
A: If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double dose.
A: This medicine can interact with many other medications. Always inform your doctor about all medicines, supplements, and herbal products you are taking.
A: No, this medicine is contraindicated during pregnancy as it may harm the developing fetus. Consult your doctor for alternative treatments.
🤔 Common Patient Concerns
🔄 Substitutes for itor 80mg tablet
View AllAlternative brands with exact same active ingredient:
-
davaindia atorvastatin 80mg tabletDavaindia Generic Pharmacy ₹51.56 77.1% CHEAPER
-
biovas 80mg tabletBiochem Pharmaceutical Industries ₹56.25 75% CHEAPER
-
danavish atorvastatin 80mg tabletDanavish Healthcare ₹62.00 72.4% CHEAPER
-
atortrue 80 tabletAvighna Medicare Pvt. Ltd. ₹74.06 67.1% CHEAPER
-
atfour 80mg tabletCorazon Pharma Pvt Ltd ₹84.38 62.5% CHEAPER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can be stopped once cholesterol levels are normal.
Fact: This medicine is usually a long-term treatment. Stopping it can cause cholesterol levels to rise again and increase cardiovascular risk. Always consult your doctor before stopping. - Myth: This medicine causes severe muscle damage in everyone.
Fact: Muscle side effects are uncommon and usually mild. Serious muscle injury is rare. Report any muscle symptoms to your doctor. - Myth: This medicine is only for people with high cholesterol.
Fact: This medicine is also used to reduce cardiovascular risk in people with normal cholesterol but other risk factors like diabetes or heart disease. - Myth: This medicine can be taken without lifestyle changes.
Fact: This medicine is most effective when combined with a healthy diet, regular exercise, and weight management.
🔄 Alternative Options
Generic Alternatives
- Atorvastatin 80 mg tablet
Brand Alternatives
- Atorva 80mg Tablet
- Storvas 80mg Tablet
- Lipitor 80mg Tablet
- Atorlip 80mg Tablet