Itraconazole 65 mg Capsule: Complete Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Yellowing of skin or eyes, dark urine, or severe abdominal pain
- Shortness of breath, swelling of legs, or sudden weight gain
- Swelling of face, lips, or throat, or difficulty breathing
- Severe skin rash with blisters or peeling
- Numbness, tingling, or pain in hands or feet
- Unusual tiredness or weakness
- Fast or irregular heartbeat
If experiencing severe symptoms, call emergency services immediately.
What is itixo sb 65mg capsule used for?
This medicine is an antifungal capsule containing Itraconazole 65 mg. It is used to treat various fungal infections of the skin, nails, and internal organs. It works by breaking down the fungal cell membrane. Take it with food as prescribed by your doctor.
- Generic Name: Itraconazole (65mg)
- Manufacturer: Aleixo Pharma
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 itixo sb 65mg capsule के बारे में (Hindi Summary)
उपयोग: यह दवा एक एंटीफंगल कैप्सूल है जिसमें इट्राकोनाज़ोल 65 मिलीग्राम होता है। इसका उपयोग त्वचा, नाखून और शरीर के आंतरिक अंगों के फंगल संक्रमण के इलाज के लिए किया जाता है। यह फंगस की कोशिका भित्ति को नष्ट करके काम करती है। इसे डॉक्टर के निर्देशानुसार भोजन के साथ लें।
साइड इफेक्ट्स: इस दवा के आम दुष्प्रभावों में सिरदर्द, मतली, पेट दर्द, दस्त और दाने शामिल हैं। गंभीर दुष्प्रभाव दुर्लभ हैं लेकिन इनमें लिवर की समस्या, हृदय विफलता और गंभीर एलर्जी शामिल हो सकती है। यदि आपको पीलिया, सांस लेने में कठिनाई, या चेहरे पर सूजन दिखे तो तुरंत डॉक्टर से मिलें।
सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। इसे भोजन के साथ लें ताकि अवशोषण बेहतर हो और पेट की परेशानी कम हो। एंटासिड या एसिड कम करने वाली दवाओं को इस दवा से 2 घंटे पहले या बाद में लें। इस दवा के साथ शराब न पिएं। यदि आप गर्भवती हैं या स्तनपान करा रही हैं तो डॉक्टर को बताएं। दवा को कमरे के तापमान पर सूखी जगह पर रखें।
💊 itixo sb 65mg capsule Uses & Benefits
- [{"condition":"Dermatophytosis (tinea corporis, tinea cruris, tinea pedis)","description":"This medicine is used to treat fungal infections of the skin caused by dermatophytes.
- It helps relieve itching, redness, and scaling.","evidence":"Well-established"},{"condition":"Onychomycosis","description":"This medicine is used to treat fungal nail infections.
- It helps clear the infection and allows healthy nail to grow.","evidence":"Well-established"},{"condition":"Aspergillosis","description":"This medicine is used to treat invasive aspergillosis in patients who cannot tolerate or do not respond to other antifungal medicines.","evidence":"Well-established"},{"condition":"Blastomycosis","description":"This medicine is used to treat blastomycosis, a fungal infection that can affect the lungs and skin.","evidence":"Well-established"},{"condition":"Histoplasmosis","description":"This medicine is used to treat histoplasmosis, a fungal infection that primarily affects the lungs.","evidence":"Well-established"},{"condition":"Candidiasis","description":"This medicine is used to treat certain types of candidiasis, including oral and esophageal candidiasis, in patients who are refractory to other treatments.","evidence":"Well-established"}]
Off-label uses: [{"condition":"Seborrheic dermatitis","description":"Sometimes prescribed off-label for seborrheic dermatitis due to its antifungal activity against Malassezia species.","evidence":"Limited"},{"condition":"Fungal keratitis","description":"Occasionally used off-label in the treatment of fungal keratitis, although topical antifungals are preferred.","evidence":"Limited"}]
Primary treatment for: Fungal infections
Also treats: Dermatophytosis, Onychomycosis, Aspergillosis, Blastomycosis, Histoplasmosis, Candidiasis
📋 Drug Information
| Generic Name(s) | Itraconazole (65mg) |
| Brand Name | itixo sb 65mg capsule |
| Manufacturer | Aleixo Pharma |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | OPHTHAL |
| Action Class | Fungal ergosterol synthesis inhibitor |
| Route of Administration | Oral |
| Storage | Store at room temperature (15-30°C) in a dry place, away from direct sunlight and moisture. Keep in the original container. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine works by inhibiting the fungal cytochrome P450 enzyme 14-alpha-demethylase, which is responsible for converting lanosterol to ergosterol. Ergosterol is a critical component of the fungal cell membrane. By blocking this step, the medicine disrupts the synthesis of ergosterol, leading to a weakened and permeable fungal cell membrane. This results in leakage of cellular contents and ultimately fungal cell death. The medicine is selective for fungal enzymes over human enzymes, which reduces its toxicity to human cells.
Mechanism Steps
💡 How to Take itixo sb 65mg capsule
Strength: Itraconazole 65 mg immediate-release capsule
Dosage Information
| Adult Dosage | The dose of this medicine must be individualized by a qualified clinician based on the indication, age, weight, renal and hepatic function. For dermatophyte infections, a typical dose is 100-200 mg once daily for 1-4 weeks. For onychomycosis, a pulse regimen of 200 mg twice daily for 1 week per month for 2-3 months may be used. For systemic fungal infections, doses may range from 100-400 mg daily. Always follow your doctor's prescription exactly. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients may be more sensitive to the side effects of this medicine. Dose adjustment may be necessary based on renal and hepatic function. Consult your doctor. |
| Renal Impairment | Dose adjustment may be needed in patients with renal impairment. Consult your doctor for individualized dosing. |
| Hepatic Impairment | This medicine is contraindicated in patients with severe liver disease. In patients with mild to moderate liver impairment, dose adjustment may be necessary. Consult your doctor. |
| Maximum Daily Dose | The maximum daily dose should not exceed 400 mg, but the exact dose depends on the indication and must be determined by a qualified clinician. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of itixo sb 65mg capsule
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Cisapride | Major | |
| Pimozide | Major | |
| Quinidine | Major | |
| Methadone | Major | |
| Disopyramide | Major | |
| Dofetilide | Major | |
| Levodopa | Major | |
| Midazolam (oral) | Major | |
| Triazolam | Major | |
| Simvastatin | Major |
🚨 Major Interactions
- Cisapride
- Pimozide
- Quinidine
- Methadone
- Disopyramide
- Dofetilide
- Levodopa
- Midazolam (oral)
- Triazolam
- HMG-CoA reductase inhibitors (statins)
⚡ Moderate Interactions
- Warfarin
- Digoxin
- Phenytoin
- Rifampicin
- Isoniazid
- Carbamazepine
- Phenobarbital
- Clarithromycin
- Erythromycin
- Protease inhibitors (e.g., ritonavir, indinavir)
🍷 Alcohol Interaction
Avoid consuming alcohol while taking this medicine, as it may increase the risk of liver damage and other side effects.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Known hypersensitivity to itraconazole or other azole antifungals","Evidence of ventricular dysfunction such as heart failure or a history of heart failure","Concurrent use with cisapride, pimozide, quinidine, methadone, disopyramide, dofetilide, levodopa, midazolam (oral), triazolam, simvastatin, lovastatin","Pregnancy for the treatment of onychomycosis","Women of childbearing potential not using effective contraception"]
⚠️ Warnings & Precautions
["This medicine should be taken with food to ensure adequate absorption.","Avoid use in patients with heart failure or a history of heart failure.","Monitor liver function in patients with pre-existing liver disease.","Use with caution in patients with renal impairment.","This medicine can interact with many drugs; review all concomitant medications.","Do not use during pregnancy for onychomycosis.","Breastfeeding is not recommended during treatment.","Avoid alcohol while taking this medicine.","May cause dizziness; avoid driving or operating machinery until you know how it affects you.","Do not share this medicine with others."]
🤱 Lactation Safety
This medicine is excreted in breast milk. Breastfeeding is not recommended while taking this medicine. Consult your doctor for guidance.
💊 Overdose Management
There is no specific antidote for overdose with this medicine. In case of overdose, seek immediate medical attention. Treatment should be symptomatic and supportive. Gastric lavage may be considered if the overdose is recent. Monitor vital signs and liver function.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up.
Additional Safety Advice
Take this medicine exactly as prescribed by your doctor. Do not take more or less than the recommended dose. Swallow the capsule whole with a full glass of water. Take this medicine with food to improve absorption and reduce stomach upset. Avoid taking antacids or stomach acid reducers within two hours of taking this medicine, as they can reduce its absorption. Do not drink alcohol while taking this medicine, as it may increase the risk of liver problems. Inform your doctor if you have a history of heart failure, liver disease, or kidney disease. This medicine can interact with many other medicines, including certain antibiotics, antidepressants, and cholesterol-lowering drugs. Always tell your doctor about all the medicines, supplements, and herbal products you are taking. Do not stop taking this medicine without consulting your doctor, even if you feel better. Complete the full course as prescribed to prevent the infection from returning. If you miss a dose, take it as soon as you remember, but if it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up. Store this medicine at room temperature, away from moisture and direct sunlight. Keep it out of reach of children. If you are pregnant, planning to become pregnant, or breastfeeding, inform your doctor before taking this medicine. This medicine may cause dizziness; avoid driving or operating heavy machinery until you know how it affects you.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients may be more susceptible to the side effects of this medicine, especially heart failure and liver toxicity. Dose adjustment may be necessary based on renal and hepatic function. Regular monitoring is advised.
🤰 Pregnancy Planning (TTC)
If you are planning to become pregnant, consult your doctor before taking this medicine. Effective contraception should be used during treatment and until the next menstrual period after treatment ends. This medicine should not be used for onychomycosis during pregnancy.
🏥 Post-Surgery Considerations
Inform your surgeon and anesthesiologist that you are taking this medicine, as it can interact with other medications used during surgery. It may also affect heart function, so monitoring may be needed.
🦷 Dental Procedures
Inform your dentist that you are taking this medicine, as it can interact with certain medications used in dental procedures. It may also increase the risk of bleeding if you are on blood thinners.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
This medicine may cause dizziness or fatigue. Avoid strenuous exercise if you feel unsteady. Consult your doctor before starting any new exercise regimen.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause dizziness or fatigue, which can affect your ability to drive or operate machinery. Avoid these activities until you know how the medicine affects you. It is generally safe to continue your daily activities, but take precautions.
🛑 When to Stop This Medicine
Do not stop taking this medicine without consulting your doctor. If you experience serious side effects such as signs of liver injury, heart failure, or severe allergic reaction, stop the medicine and seek immediate medical attention. Your doctor will advise you on whether to continue or stop.
📅 Long-Term Use Effects
Long-term use of this medicine may increase the risk of liver injury, heart failure, and peripheral neuropathy. Regular monitoring of liver function and heart function is recommended. The medicine may also cause drug interactions that require dose adjustments. Consult your doctor for regular check-ups if you are on prolonged therapy.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
For mild skin fungal infections, topical creams may be sufficient.
Evidence: Well-establishedAn alternative oral antifungal for dermatophyte infections.
Evidence: Well-establishedAnother oral antifungal for certain fungal infections.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
This medicine may interact with live vaccines. Consult your doctor before receiving any vaccination while on this medicine.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
When traveling, carry this medicine in its original packaging along with a copy of your prescription. Store it at room temperature, away from direct sunlight and moisture. If crossing time zones, continue taking the medicine at the same intervals as prescribed; consult your doctor for specific advice. Declare the medicine at customs if required. Keep it in your carry-on luggage to avoid loss.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: Improvement in skin infections may be seen within 1-2 weeks. Nail infections may take several weeks to months to clear.
A: Yes, take it with a full meal to improve absorption and reduce stomach upset.
A: Take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose.
A: This medicine should not be used during pregnancy for onychomycosis. For other indications, consult your doctor to weigh the benefits and risks.
A: No, avoid alcohol as it may increase the risk of liver problems.
🤔 Common Patient Concerns
🔄 Substitutes for itixo sb 65mg capsule
View AllAlternative brands with exact same active ingredient:
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apexitra sb 65 capsuleApex Laboratories Pvt Ltd ₹131.25 30% CHEAPER
-
nixitral ed 65 capsuleCanixa Life Sciences Pvt ₹131.25 30% CHEAPER
-
itralase sb 65mg capsuleCipla Ltd ₹153.14 18.3% CHEAPER
-
canditral sb 65 capsuleGlenmark Pharmaceuticals Ltd ₹157.50 16% CHEAPER
-
syntran sb 65 capsuleGlenmark Pharmaceuticals Ltd ₹157.50 16% CHEAPER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can cure any fungal infection quickly.
Fact: This medicine is effective for many fungal infections but requires the full prescribed course and may take weeks to months for complete cure, especially for nail infections. - Myth: It is safe to stop this medicine once symptoms improve.
Fact: Stopping early can lead to recurrence of the infection. Always complete the full course as prescribed. - Myth: This medicine can be taken on an empty stomach.
Fact: This medicine should be taken with food to ensure proper absorption and reduce stomach upset.
🔄 Alternative Options
Generic Alternatives
- Itraconazole 65 mg capsule
Brand Alternatives
- Itraconazole 65 mg capsule (various manufacturers)