Monosprin 30 Capsule SR: Complete Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Blood in stool or vomit
- Severe abdominal pain
- Chest pain or difficulty breathing
- Severe headache with visual changes
- Sudden swelling of face, lips, or throat
- Yellowing of skin or eyes
- Decreased urine output
If experiencing severe symptoms, call emergency services immediately.
What is isoloprin 30mg/75mg capsule used for?
This medicine is a combination of Isosorbide Mononitrate and Aspirin used to prevent heart attacks and strokes in patients with cardiovascular disease. It works by relaxing blood vessels and preventing blood clots.
- Generic Name: Isosorbide Mononitrate (30mg) + Aspirin (75mg)
- Manufacturer: Torrent Pharmaceuticals Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 isoloprin 30mg/75mg capsule के बारे में (Hindi Summary)
उपयोग: यह दवा मुख्य रूप से हृदय रोगों जैसे एंजाइना (सीने में दर्द), दिल का दौरा और स्ट्रोक को रोकने के लिए इस्तेमाल की जाती है। यह रक्त वाहिकाओं को फैलाकर और रक्त के थक्के बनने से रोककर काम करती है।
साइड इफेक्ट्स: आम दुष्प्रभावों में सिरदर्द, चक्कर आना, चेहरे पर गर्मी लगना और पेट में जलन शामिल हैं। गंभीर दुष्प्रभावों में बहुत कम रक्तचाप, रक्तस्राव, और एलर्जी प्रतिक्रियाएं हो सकती हैं। यदि आपको असामान्य रक्तस्राव, सांस लेने में कठिनाई, या गंभीर सिरदर्द हो तो तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: इस दवा को डॉक्टर के निर्देशानुसार ही लें। इसे चबाएं या तोड़ें नहीं, पूरा निगल लें। शराब का सेवन न करें क्योंकि इससे रक्तचाप कम हो सकता है और पेट में रक्तस्राव का खतरा बढ़ सकता है। अन्य दवाओं के साथ इसका सेवन करने से पहले डॉक्टर से सलाह लें। नियमित रूप से रक्तचाप और रक्तस्राव के संकेतों की जांच कराएं।
💊 isoloprin 30mg/75mg capsule Uses & Benefits
[{"condition":"Chronic stable angina","description":"Used for the long-term prophylaxis of angina pectoris due to coronary artery disease.","evidence":"Well-established"},{"condition":"Secondary prevention of myocardial infarction","description":"Reduces the risk of recurrent heart attack in patients with a history of myocardial infarction.","evidence":"Well-established"},{"condition":"Secondary prevention of stroke","description":"Helps prevent recurrent ischemic stroke in high-risk patients.","evidence":"Well-established"},{"condition":"Post-coronary artery bypass graft (CABG)","description":"Used to maintain graft patency and prevent thrombotic events after CABG surgery.","evidence":"Well-established"}]
Off-label uses: [{"condition":"Prevention of preeclampsia","description":"Low-dose aspirin is sometimes used off-label to reduce the risk of preeclampsia in high-risk pregnancies; however, the combination with isosorbide mononitrate is not standard.","evidence":"Limited"}]
Primary treatment for: Cardiovascular disease
Also treats: Angina pectoris, Myocardial infarction, Ischemic stroke, Coronary artery disease
📋 Drug Information
| Generic Name(s) | Isosorbide Mononitrate (30mg) + Aspirin (75mg) |
| Brand Name | isoloprin 30mg/75mg capsule |
| Manufacturer | Torrent Pharmaceuticals Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | CARDIAC |
| Action Class | |
| Route of Administration | Oral |
| Storage | Store at room temperature (15-30°C) in a dry place, away from direct sunlight and moisture. Keep out of reach of children. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
Isosorbide Mononitrate acts by releasing nitric oxide, which stimulates guanylate cyclase, leading to increased cyclic GMP. This causes relaxation of vascular smooth muscle, predominantly on veins, resulting in reduced preload and decreased myocardial oxygen demand. Aspirin irreversibly inhibits cyclooxygenase-1 (COX-1) and COX-2 enzymes, thereby blocking the synthesis of thromboxane A2, a potent platelet aggregator and vasoconstrictor. This antiplatelet effect helps prevent thrombus formation.
Mechanism Steps
💡 How to Take isoloprin 30mg/75mg capsule
Strength: Sustained-release capsule containing Isosorbide Mononitrate 30 mg and Aspirin 75 mg.
Dosage Information
| Adult Dosage | The usual adult dose is one capsule (Isosorbide Mononitrate 30 mg + Aspirin 75 mg) taken orally once daily, preferably at the same time each day. The dose may be adjusted by your doctor based on your condition and response. Do not exceed the prescribed dose. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients may be more sensitive to the effects of this medicine, especially hypotension and bleeding. Use with caution and monitor closely. Dose adjustments may be necessary based on renal and hepatic function. |
| Renal Impairment | Use with caution in patients with renal impairment. Aspirin may accumulate and increase the risk of toxicity. Monitor renal function and adjust dose as needed. |
| Hepatic Impairment | Use with caution in patients with hepatic impairment. Isosorbide Mononitrate is extensively metabolized in the liver; dose adjustment may be required. Monitor liver function. |
| Maximum Daily Dose | The maximum recommended daily dose is one capsule (Isosorbide Mononitrate 30 mg + Aspirin 75 mg). Do not exceed without medical advice. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of isoloprin 30mg/75mg capsule
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | |
| Ibuprofen | Major | |
| Sildenafil | Major | |
| Methotrexate | Major | |
| Antihypertensives | Moderate | |
| Corticosteroids | Moderate | |
| SSRIs | Moderate | |
| Antacids | Minor | |
| Ginkgo biloba | Minor | |
| Alcohol | Major |
🚨 Major Interactions
- Warfarin
- Other NSAIDs (e.g., ibuprofen)
- Phosphodiesterase-5 inhibitors (e.g., sildenafil)
- Methotrexate
⚡ Moderate Interactions
- Antihypertensives
- Corticosteroids
- SSRIs
🍷 Alcohol Interaction
Alcohol should be avoided while taking this medicine. It can potentiate the blood pressure-lowering effect of isosorbide mononitrate, leading to dizziness, fainting, and falls. Additionally, alcohol increases the risk of gastrointestinal bleeding associated with aspirin.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Hypersensitivity to isosorbide mononitrate, aspirin, or any component of the formulation","Active bleeding or bleeding disorders","Severe hypotension","Concurrent use with phosphodiesterase-5 inhibitors (e.g., sildenafil)","Aspirin-induced asthma or NSAID hypersensitivity","Severe hepatic or renal impairment","Third trimester of pregnancy (aspirin)"]
⚠️ Warnings & Precautions
["Avoid abrupt discontinuation of isosorbide mononitrate to prevent rebound angina.","Use with caution in patients with glaucoma or increased intracranial pressure.","Aspirin may increase the risk of Reye's syndrome in children with viral infections.","Monitor for signs of gastrointestinal bleeding, especially in elderly patients.","Use with caution in patients with asthma or allergies.","Do not use in patients with severe anemia.","May cause dizziness; avoid driving or operating machinery until you know how it affects you."]
🤱 Lactation Safety
Isosorbide Mononitrate and Aspirin are excreted in breast milk. Consult your doctor before breastfeeding while on this medicine.
💊 Overdose Management
Overdose may cause severe hypotension, headache, flushing, dizziness, and tachycardia. In case of overdose, seek immediate medical attention. Treatment is supportive and symptomatic. Activated charcoal may be administered if within 1-2 hours of ingestion. Monitor vital signs and provide intravenous fluids if needed.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double dose.
Additional Safety Advice
Take this medicine exactly as prescribed. Do not crush or chew the capsule; swallow it whole. Avoid alcohol as it may increase the risk of low blood pressure and stomach bleeding. Do not use this medicine if you have active bleeding, severe anemia, or a history of aspirin-induced asthma. Inform your doctor about all other medications you are taking, especially blood thinners, NSAIDs, and antihypertensives. Regular monitoring of blood pressure, heart rate, and signs of bleeding is advised. Do not stop this medicine abruptly without consulting your doctor.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients are at higher risk of gastrointestinal bleeding, hypotension, and renal impairment. Use with caution and monitor closely. Dose adjustments may be needed.
🤰 Pregnancy Planning (TTC)
Consult your doctor if you are planning pregnancy. Aspirin use in pregnancy should be discussed; isosorbide mononitrate is not recommended unless clearly needed.
🏥 Post-Surgery Considerations
Inform your surgeon about this medicine before any surgery. It may need to be stopped temporarily due to bleeding risk. Follow your doctor's instructions.
🦷 Dental Procedures
Inform your dentist about this medicine before any dental procedure. It may increase bleeding risk. Your dentist may recommend stopping it temporarily.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Avoid strenuous exercise until you know how this medicine affects you, as it may cause dizziness or hypotension. Consult your doctor before starting any new exercise regimen.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause dizziness or lightheadedness, affecting your ability to drive or operate machinery. Avoid these activities until you know how it affects you. It is generally safe for office work.
🛑 When to Stop This Medicine
Do not stop this medicine without consulting your doctor. If you experience severe side effects, contact your doctor immediately for guidance.
📅 Long-Term Use Effects
Long-term use may increase the risk of gastrointestinal bleeding, renal impairment, and hypotension. Regular monitoring of blood pressure, renal function, and signs of bleeding is recommended. Do not stop without medical advice.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Diet, exercise, and stress management can complement medicine.
Evidence: Well-establishedClopidogrel may be used if aspirin is not tolerated.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
No specific vaccine interactions are established. However, consult your doctor before receiving any live vaccines while on this medicine.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
Carry this medicine in its original packaging with a copy of your prescription. Store at room temperature and protect from moisture. When crossing time zones, adjust dosing times gradually under medical advice. Declare it to customs if required. Keep enough supply for your trip.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: Isosorbide Mononitrate starts working within 30-60 minutes, while Aspirin's antiplatelet effect begins within 1 hour but full effect may take several days.
A: Consult your doctor before taking any other painkillers, especially NSAIDs, as they can interact and increase bleeding risk.
A: No, stopping abruptly can worsen angina. Always consult your doctor before stopping.
🤔 Common Patient Concerns
🔄 Substitutes for isoloprin 30mg/75mg capsule
View AllAlternative brands with exact same active ingredient:
-
vasoprin ls 30 mg/75 mg tabletTorrent Pharmaceuticals Ltd ₹8.90 70.3% CHEAPER
-
monosprin 30 capsule srSun Pharmaceutical Industries Ltd ₹17.75 40.8% CHEAPER
-
nitren 30mg/75mg capsuleWockhardt Ltd ₹22.03 26.6% CHEAPER
-
ismorin 30 mg/75 mg capsuleAbbott ₹23.27 22.4% CHEAPER
-
nitroprin 30 mg/75 mg tabletLife Medicare & Biotech Pvt Ltd ₹26.78 10.7% CHEAPER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can be taken on an empty stomach.
Fact: It should be taken with food to reduce stomach irritation. - Myth: You can stop this medicine once you feel better.
Fact: It is usually a long-term treatment; stopping abruptly can increase risk of heart attack or stroke. - Myth: This medicine is safe to take with any other painkiller.
Fact: It can interact dangerously with other NSAIDs and blood thinners.
🔄 Alternative Options
Generic Alternatives
- Isosorbide Mononitrate 30 mg + Aspirin 75 mg sustained-release capsules
Brand Alternatives
- Monosprin 30 Capsule SR