Bionect Ointment: Complete Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Swelling of the face, lips, or throat or difficulty breathing
- Severe burning, pain, or blistering at the application site
- Spreading redness or red streaks from the wound
- Fever with chills or worsening wound discharge
- Bluish discoloration of lips or skin
- Decreased urine output or swelling in legs
- Yellowing of skin or eyes
If experiencing severe symptoms, call emergency services immediately.
What is intadine o ointment used for?
This medicine is a topical ointment combining povidone iodine 5% w/w and ornidazole 1% w/w. It is used to treat and prevent infections in wounds, burns, and skin ulcers by killing bacteria, fungi, and protozoa. Apply a thin layer to the affected area as directed by your doctor.
- Generic Name: Povidone Iodine (5% w/w) + Ornidazole (1% w/w)
- Manufacturer: Intas Pharmaceuticals Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 intadine o ointment के बारे में (Hindi Summary)
उपयोग: यह दवा एक टॉपिकल ऑइंटमेंट है जिसमें पोविडोन आयोडीन 5% w/w और ओर्निडाज़ोल 1% w/w शामिल हैं। इसका उपयोग संक्रमित घावों, जलने, अल्सर और त्वचा संक्रमण के इलाज और रोकथाम के लिए किया जाता है। पोविडोन आयोडीन बैक्टीरिया, फंगस और वायरस को मारता है, जबकि ओर्निडाज़ोल एनारोबिक बैक्टीरिया और प्रोटोज़ोआ को नष्ट करता है। यह दवा केवल बाहरी उपयोग के लिए है और डॉक्टर के निर्देशानुसार प्रभावित क्षेत्र पर पतली परत में लगानी चाहिए।
साइड इफेक्ट्स: आम दुष्प्रभावों में लगाने की जगह पर हल्की जलन, खुजली, लालिमा या सूजन शामिल हैं। कुछ लोगों में त्वचा का रंग भूरा हो सकता है, जो दवा बंद करने पर ठीक हो जाता है। कभी-कभी एलर्जी वाली प्रतिक्रिया हो सकती है जैसे दाने, छाले या सूजन। यदि सांस लेने में कठिनाई, चेहरे या गले में सूजन हो, तो तुरंत डॉक्टर से मिलें।
सुरक्षा सलाह: इस दवा को केवल प्रभावित त्वचा पर लगाएं और आंखों, कानों, मुंह तथा अन्य श्लेष्मा झिल्लियों से बचाएं। लगाने से पहले और बाद में हाथ धोएं। बड़े घावों या जलने पर बिना डॉक्टर की सलाह के इसका उपयोग न करें क्योंकि आयोडीन रक्त में जा सकता है। गर्भवती या स्तनपान कराने वाली महिलाएं और थायरॉइड विकार वाले मरीज़ डॉक्टर से परामर्श करें। बच्चों की पहुंच से दूर रखें।
💊 intadine o ointment Uses & Benefits
[{"condition":"Infected wounds","description":"Used to disinfect and treat wounds that have become contaminated with bacteria, including anaerobic organisms.","evidence":"Well-established"},{"condition":"Burns","description":"Helps prevent infection in superficial and partial-thickness burns by reducing microbial load.","evidence":"Well-established"},{"condition":"Skin ulcers","description":"Applied to pressure ulcers, diabetic foot ulcers, and venous ulcers to control infection and promote healing.","evidence":"Moderate"},{"condition":"Bacterial skin infections","description":"Treats localized skin infections such as impetigo, folliculitis, and infected dermatitis when caused by susceptible organisms.","evidence":"Moderate"},{"condition":"Fungal skin infections","description":"Povidone iodine provides antifungal activity against dermatophytes and yeasts, complementing ornidazole's antibacterial action.","evidence":"Limited"}]
Off-label uses: [{"condition":"Preoperative skin preparation","description":"Sometimes used off-label to reduce skin flora before minor surgical procedures.","evidence":"Limited"},{"condition":"Oral mucositis","description":"Occasionally used as a mouth rinse or gel in diluted form for oral ulcers, but not a standard use for this ointment.","evidence":"Limited"}]
Primary treatment for: Infected wounds and skin infections
Also treats: Burns, Skin ulcers, Impetigo, Folliculitis
📋 Drug Information
| Generic Name(s) | Povidone Iodine (5% w/w) + Ornidazole (1% w/w) |
| Brand Name | intadine o ointment |
| Manufacturer | Intas Pharmaceuticals Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | DERMA |
| Action Class | |
| Route of Administration | Topical |
| Storage | Store below 25°C in a cool, dry place. Protect from direct sunlight and moisture. Keep the tube tightly closed when not in use. |
| Shelf Life | 24 months from the date of manufacture, or as printed on the packaging. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine works through two complementary mechanisms. Povidone iodine is a stable complex of iodine with polyvinylpyrrolidone. When applied to skin, it slowly releases free iodine, which oxidizes and denatures microbial proteins, enzymes, and nucleic acids, leading to rapid killing of bacteria, fungi, viruses, and protozoa. Ornidazole is a nitroimidazole that enters anaerobic microorganisms and is reduced by their electron transport proteins to reactive intermediates. These intermediates bind to DNA, causing strand breakage and inhibiting nucleic acid synthesis, which results in cell death. The combination provides broad-spectrum surface antisepsis and targeted antimicrobial activity against anaerobes.
Mechanism Steps
💡 How to Take intadine o ointment
Strength: Ointment containing povidone iodine 5% w/w and ornidazole 1% w/w.
Dosage Information
| Adult Dosage | Apply a thin layer of this medicine to the affected area once or twice daily, or as directed by your doctor. Clean the area gently before application. The duration of treatment depends on the type and severity of the infection. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. Use in children should be supervised by a doctor, especially on large areas or broken skin. |
| Elderly Dosage | Elderly patients may be more susceptible to iodine absorption and thyroid effects. Use with caution and monitor thyroid function if prolonged use is required. Dose must be individualized by a qualified clinician. |
| Renal Impairment | No specific dose adjustment is established for topical use. Use with caution in patients with severe kidney disease and monitor for signs of iodine toxicity. |
| Hepatic Impairment | No specific dose adjustment is established for topical use. Use with caution in patients with severe liver disease. |
| Maximum Daily Dose | Not established from the available information. Follow your doctor's prescription. |
Dosage Timeline
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of intadine o ointment
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Lithium | Major | |
| Warfarin | Major | |
| Mercury antiseptics | Moderate | |
| Silver sulfadiazine | Moderate | |
| Hydrogen peroxide | Minor | |
| Topical corticosteroids | Minor |
🚨 Major Interactions
- Lithium
- Warfarin
⚡ Moderate Interactions
- Mercury-containing antiseptics
- Silver sulfadiazine
🍷 Alcohol Interaction
No specific interaction between this topical medicine and alcohol is established. However, alcohol may worsen underlying conditions or interact with other medicines you are taking. Consult your doctor about alcohol use while on treatment.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Known allergy to povidone iodine, iodine, or ornidazole","Thyroid disorders such as hyperthyroidism or thyroid adenoma","Severe kidney disease","Use on large areas of broken skin without medical supervision","Use in premature infants or neonates"]
⚠️ Warnings & Precautions
["For external use only. Do not swallow.","Avoid contact with eyes, ears, and mucous membranes.","Do not use on large wounds or burns without medical advice.","Prolonged use may cause iodine absorption and thyroid dysfunction.","Discontinue if severe irritation or allergic reaction occurs.","Use with caution in patients with thyroid or kidney disease.","Do not use under airtight dressings unless instructed.","Keep out of reach of children."]
🤱 Lactation Safety
Povidone iodine can be absorbed and excreted in breast milk. Avoid applying to the breast area before breastfeeding. Consult your doctor before use during breastfeeding.
💊 Overdose Management
Overdose from topical application is unlikely but may occur if large amounts are ingested or applied to extensive areas. Symptoms of iodine toxicity include metallic taste, vomiting, abdominal pain, diarrhea, dehydration, and shock. Seek immediate medical attention. Treatment is supportive and symptomatic. If ingested, do not induce vomiting; give milk or water if the patient is conscious and seek emergency care.
⏰ Missed Dose
If you miss a dose, apply it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not apply a double dose to make up for a missed one.
Additional Safety Advice
Apply this medicine only to the affected area and avoid contact with eyes, ears, mouth, and other mucous membranes. Wash your hands thoroughly before and after application unless your hands are the treated area. Do not cover the area with airtight dressings unless your doctor specifically instructs you to do so. Avoid using this medicine on large open wounds or burns without medical supervision because iodine can be absorbed into the bloodstream. Do not use it for more than the recommended duration without consulting your doctor. If you are pregnant, breastfeeding, or have a thyroid disorder, speak to your doctor before using this medicine. Keep this medicine out of reach of children and store it in a cool, dry place away from direct sunlight.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients are more prone to iodine absorption and thyroid dysfunction. Use with caution, especially on large areas or for prolonged periods. Monitor thyroid function if necessary.
🤰 Pregnancy Planning (TTC)
If you are planning pregnancy, consult your doctor before using this medicine. Povidone iodine can affect thyroid function in the fetus, so use only if clearly needed.
🏥 Post-Surgery Considerations
This medicine may be used on surgical wounds to prevent infection, but follow your surgeon's instructions. Do not apply to surgical incisions without medical advice.
🦷 Dental Procedures
This medicine is not intended for oral use. For dental procedures, inform your dentist about any medicines you are using, including this topical ointment.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Avoid strenuous exercise that may put pressure on the affected area or cause sweating and irritation. Gentle movement is fine, but protect the wound from friction and moisture.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine is applied topically and is unlikely to affect your ability to drive or operate machinery. However, if you experience dizziness or allergic reactions, avoid driving until you feel better. Keep the treated area covered if you work in a dirty environment.
🛑 When to Stop This Medicine
Stop using this medicine when the infection clears or as advised by your doctor. Do not stop prematurely if you feel better, as the infection may return. If you experience severe irritation or allergic reaction, stop immediately and consult your doctor.
📅 Long-Term Use Effects
Prolonged use on large areas can lead to systemic iodine absorption, which may affect thyroid function and cause thyroid dysfunction. Ornidazole absorption through skin is limited, but long-term use may rarely cause systemic effects. Regular monitoring of thyroid function is advised if prolonged use is necessary. Do not use for longer than prescribed without medical review.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Cleaning wounds with sterile saline helps remove debris and bacteria.
Evidence: Well-establishedMedical-grade honey has antimicrobial properties and can be used for wound care.
Evidence: ModerateSilver-impregnated dressings provide antimicrobial action for chronic wounds.
Evidence: Moderate💉 Vaccination Considerations
💉 If You're Getting Vaccinated
No specific interaction between this topical medicine and vaccines is established. However, if you have an active infection, consult your doctor about the timing of vaccinations.
📦 Storage Guide
✅ DO
Store at room temperature below 25°C
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in the original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in the bathroom cabinet
✅ DO
Keep the tube tightly closed
❌ DON'T
Do not use after the expiry date
✈️ Traveling with This Medicine
Carry this medicine in its original packaging with the prescription label intact. Bring a copy of your prescription in case customs or security asks for documentation. Store it in a cool, dry place away from direct sunlight during travel. If traveling by air, keep it in your carry-on bag if you need it during the flight. Avoid exposing the tube to extreme temperatures.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: The antiseptic action starts within minutes, but visible improvement in infection may take 2 to 3 days. Consult your doctor if there is no improvement after 3 to 5 days.
A: It can be used on the face if prescribed, but avoid contact with eyes and mucous membranes. Use a thin layer and be cautious of skin discoloration.
A: Use during pregnancy only if clearly needed and under medical supervision. Iodine can affect the fetal thyroid, especially with prolonged use on large areas.
A: Yes, it can be used on minor burns to prevent infection, but large or deep burns require medical supervision.
A: Apply it as soon as you remember. If it is almost time for the next dose, skip the missed dose and continue with your regular schedule. Do not double dose.
🤔 Common Patient Concerns
🔄 Substitutes for intadine o ointment
View AllAlternative brands with exact same active ingredient:
-
povitino oz ointmentRoma Pharma Pvt Ltd ₹44.30 48.1% CHEAPER
-
Topovid OZ OintmentElder Pharmaceuticals Ltd ₹46.00 46.1% CHEAPER
-
ubidine o ointmentUniphar Biotech Private Limited ₹47.00 44.9% CHEAPER
-
dopi o ointmentDaksh Pharma Pvt Ltd ₹48.00 43.7% CHEAPER
-
qugyl op ointmentRPG Life Sciences Ltd ₹49.00 42.6% CHEAPER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can be used for any skin problem.
Fact: It is specifically for infected wounds and skin infections. Using it for other conditions may not help and can cause irritation. - Myth: More ointment means faster healing.
Fact: Applying a thick layer does not speed healing and may increase side effects. Use a thin layer as directed. - Myth: It is safe to use on large open wounds without supervision.
Fact: Povidone iodine can be absorbed through broken skin and affect the thyroid. Large wounds require medical supervision.
🔄 Alternative Options
Generic Alternatives
- Povidone iodine 5% w/w + Ornidazole 1% w/w ointment
Brand Alternatives
- Bionect Ointment