Inat 50mg/1.5mg Tablet: Comprehensive Guide to Uses, Side Effects, and Safety
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Severe dizziness or fainting
- Very slow or irregular heartbeat
- Difficulty breathing or wheezing
- Chest pain or tightness
- Sudden swelling of face, lips, or throat
- Severe muscle cramps or weakness
- Decreased urine output or swelling in legs
- Yellowing of skin or eyes
If experiencing severe symptoms, call emergency services immediately.
What is inat 50mg/1.5mg tablet used for?
This medicine is a combination of Atenolol (a beta-blocker) and Indapamide (a diuretic) used to treat high blood pressure. It works by slowing the heart rate and removing excess fluid from the body, thereby lowering blood pressure and reducing the risk of heart attack and stroke.
- Generic Name: Atenolol (50mg) + Indapamide (1.5mg)
- Manufacturer: Siomond Pharmaceuticals Pvt Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 inat 50mg/1.5mg tablet के बारे में (Hindi Summary)
उपयोग: यह दवा उच्च रक्तचाप (हाइपरटेंशन) के इलाज के लिए इस्तेमाल की जाती है। इसमें एटेनोलोल और इंडापामाइड दो सक्रिय तत्व हैं। एटेनोलोल दिल की धड़कन को धीमा करता है और रक्तचाप को कम करता है, जबकि इंडापामाइड शरीर से अतिरिक्त नमक और पानी को बाहर निकालता है। यह दवा अकेले एक दवा से रक्तचाप नियंत्रित न होने पर डॉक्टर द्वारा लिखी जाती है। यह दिल के दौरे और स्ट्रोक के खतरे को कम करने में मदद करती है।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में थकान, चक्कर आना, ठंडे हाथ-पैर, धीमी हृदय गति, सिरदर्द और बार-बार पेशाब आना शामिल हैं। कुछ मरीजों को पेट खराब, जी मिचलाना या हल्के दाने हो सकते हैं। गंभीर लेकिन दुर्लभ दुष्प्रभावों में बहुत धीमी हृदय गति, हृदय रुकावट, अस्थमा में सांस लेने में कठिनाई, इलेक्ट्रोलाइट असंतुलन और गाउट शामिल हैं। यदि आपको बेहोशी, सीने में दर्द, सांस लेने में तकलीफ या मांसपेशियों में ऐंठन हो, तो तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। इसे अचानक बंद न करें, क्योंकि इससे एनजाइना या दिल का दौरा पड़ सकता है। अगर आपको अस्थमा, मधुमेह, गुर्दे या लीवर की बीमारी है, तो डॉक्टर को बताएं। शराब न पिएं क्योंकि इससे चक्कर आ सकते हैं। पर्याप्त पानी पिएं जब तक डॉक्टर अन्यथा न कहें। बैठने या लेटने से उठते समय धीरे-धीरे उठें। नियमित रूप से रक्तचाप और हृदय गति की जांच कराएं। बिना डॉक्टर की सलाह के पोटेशियम सप्लीमेंट न लें।
💊 inat 50mg/1.5mg tablet Uses & Benefits
- [{"condition":"Hypertension","description":"This medicine is used to treat high blood pressure when a combination of a beta-blocker and a diuretic is needed to achieve target blood pressure.
- It helps reduce the risk of stroke, heart attack, and kidney damage.","evidence":"Well-established"},{"condition":"Angina pectoris","description":"Atenolol component helps reduce the frequency and severity of angina attacks by decreasing heart rate and oxygen demand.
- Indapamide may provide additional blood pressure control.","evidence":"Well-established for atenolol; combination use is supportive."}]
Off-label uses: [{"condition":"Migraine prophylaxis","description":"Atenolol is sometimes used off-label to prevent migraines, though indapamide is not typically used for this purpose. The combination is not standard for migraine prevention.","evidence":"Limited"},{"condition":"Performance anxiety","description":"Beta-blockers like atenolol are occasionally used off-label for situational anxiety, but the diuretic component is not appropriate for this indication.","evidence":"Limited"}]
Primary treatment for: Hypertension
Also treats: Angina pectoris, Heart failure (stable, as part of therapy)
📋 Drug Information
| Generic Name(s) | Atenolol (50mg) + Indapamide (1.5mg) |
| Brand Name | inat 50mg/1.5mg tablet |
| Manufacturer | Siomond Pharmaceuticals Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | CARDIAC |
| Action Class | |
| Route of Administration | Oral |
| Storage | Store at room temperature between 15°C and 30°C (59°F to 86°F). Protect from light and moisture. Keep in the original container. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine combines two antihypertensive agents with complementary mechanisms. Atenolol is a cardioselective beta-1 adrenergic receptor blocker that reduces heart rate, myocardial contractility, and cardiac output, thereby lowering blood pressure. It also inhibits renin release from the kidneys. Indapamide is a thiazide-like diuretic that inhibits sodium reabsorption in the distal convoluted tubule of the nephron, increasing excretion of sodium, chloride, and water. This reduces plasma volume and peripheral vascular resistance. The combined effect provides more effective blood pressure reduction than either agent alone.
Mechanism Steps
💡 How to Take inat 50mg/1.5mg tablet
Strength: Tablet containing Atenolol 50 mg and Indapamide 1.5 mg.
Dosage Information
| Adult Dosage | The usual adult dose of this medicine is one tablet taken orally once daily, preferably in the morning. The dose may be adjusted by your doctor based on your blood pressure response and tolerance. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Do not exceed the prescribed dose. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients may be more sensitive to the effects of this medicine, particularly dizziness and electrolyte imbalances. Start with a lower dose and monitor closely. Dose must be individualized by a qualified clinician. |
| Renal Impairment | Use with caution in patients with renal impairment. Atenolol is excreted renally and may require dose reduction if creatinine clearance is below 35 mL/min. Indapamide is less effective in severe renal impairment and may worsen renal function. Consult your doctor for dose adjustment. |
| Hepatic Impairment | Use with caution in patients with hepatic impairment. Indapamide is metabolized in the liver, and its half-life may be prolonged. Dose adjustment may be necessary. Consult your doctor. |
| Maximum Daily Dose | The maximum recommended daily dose is one tablet (Atenolol 50 mg + Indapamide 1.5 mg) once daily. Do not exceed this dose unless directed by your doctor. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of inat 50mg/1.5mg tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Verapamil | Major | |
| Clonidine | Major | |
| Lithium | Major | |
| Digoxin | Major | |
| NSAIDs | Moderate | |
| Insulin | Moderate | |
| Corticosteroids | Moderate | |
| MAO inhibitors | Moderate | |
| Antacids | Minor | |
| Thyroid hormones | Minor |
🚨 Major Interactions
- Verapamil or diltiazem
- Clonidine
- Lithium
- Digoxin
- Corticosteroids
⚡ Moderate Interactions
- NSAIDs (e.g., ibuprofen, naproxen)
- Insulin and oral antidiabetics
- Other antihypertensives
- MAO inhibitors
🍷 Alcohol Interaction
Alcohol may enhance the blood pressure-lowering effects of this medicine, leading to dizziness, lightheadedness, and fainting. It is advisable to avoid or limit alcohol consumption while taking this medicine.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Severe bradycardia","Second or third-degree heart block","Cardiogenic shock","Decompensated heart failure","Severe renal impairment (creatinine clearance
⚠️ Warnings & Precautions
["Do not stop this medicine abruptly, as it can worsen angina or precipitate a heart attack.","Use with caution in patients with asthma or COPD; beta-blockers can cause bronchospasm.","May mask symptoms of hypoglycemia in diabetic patients.","Can cause electrolyte imbalances; monitor potassium and sodium levels.","May worsen peripheral vascular disease.","Use with caution in patients with psoriasis, as beta-blockers can exacerbate the condition.","Avoid in patients with a history of sulfonamide allergy due to indapamide.","May cause dizziness; avoid driving or operating machinery until you know how it affects you."]
🤱 Lactation Safety
Atenolol is excreted in breast milk and may cause bradycardia and hypoglycemia in the nursing infant. Indapamide is also excreted in breast milk. This medicine is not recommended during breastfeeding. Consult your doctor for alternative treatments.
💊 Overdose Management
Overdose of this medicine can cause severe bradycardia, hypotension, heart failure, bronchospasm, and electrolyte disturbances. Seek immediate medical attention. Treatment is supportive and symptomatic, including gastric lavage if recent ingestion, administration of activated charcoal, atropine for bradycardia, intravenous fluids for hypotension, and correction of electrolyte imbalances. Hemodialysis may be considered for atenolol removal.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for a missed one.
Additional Safety Advice
Take this medicine exactly as prescribed by your doctor. Do not stop taking it suddenly, as abrupt withdrawal of atenolol can worsen angina or cause a heart attack. Inform your doctor if you have asthma, diabetes, kidney or liver disease, or a history of heart failure. Avoid alcohol while taking this medicine, as it can enhance blood pressure-lowering effects and increase dizziness. Drink adequate fluids unless your doctor advises otherwise. Stand up slowly from sitting or lying positions to prevent dizziness. Monitor your blood pressure and heart rate regularly as advised. Do not use potassium supplements or salt substitutes without consulting your doctor, as indapamide can affect potassium levels. If you are scheduled for surgery or dental procedures, inform your healthcare provider about this medicine. Keep all follow-up appointments for blood tests to check kidney function and electrolyte levels.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients are more prone to dizziness, electrolyte imbalances, and falls. Start with a lower dose and monitor closely. Regular check-ups for kidney function and electrolytes are important.
🤰 Pregnancy Planning (TTC)
This medicine is not recommended during pregnancy as it may harm the fetus. If you are planning pregnancy, consult your doctor to switch to a safer alternative before conception.
🏥 Post-Surgery Considerations
Inform your surgeon and anesthesiologist that you are taking this medicine. It may interact with anesthetic agents and affect blood pressure and heart rate during surgery. Your doctor may advise temporary discontinuation or dose adjustment.
🦷 Dental Procedures
Inform your dentist that you are taking this medicine, as it can interact with certain local anesthetics and affect blood pressure. Your dentist may take precautions to monitor your blood pressure during the procedure.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Moderate exercise is generally safe, but avoid sudden strenuous activities, especially in hot weather, as this medicine can cause dehydration and dizziness. Stay hydrated and monitor your heart rate during exercise. Consult your doctor before starting any new exercise program.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause dizziness or fatigue, especially when you first start taking it. Avoid driving or operating heavy machinery until you know how it affects you. Most people can continue their normal work activities, but take precautions if your job involves heights or heavy machinery.
🛑 When to Stop This Medicine
Do not stop taking this medicine without consulting your doctor. If you experience severe side effects or your doctor decides to discontinue it, they will gradually reduce the dose to prevent withdrawal effects such as rebound hypertension or angina.
📅 Long-Term Use Effects
Long-term use of this medicine may require regular monitoring of blood pressure, heart rate, kidney function, and electrolyte levels. Prolonged use of indapamide can lead to electrolyte imbalances, increased uric acid levels, and reduced glucose tolerance. Atenolol may cause fatigue, cold extremities, and sexual dysfunction. Regular follow-up with your doctor is essential to adjust the dose and manage any side effects.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Diet, exercise, and weight loss can help lower blood pressure and may reduce the need for medication.
Evidence: Well-establishedACE inhibitors, ARBs, calcium channel blockers, or other combinations may be alternatives if this medicine is not suitable.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
No specific vaccine interactions are known. However, inform your healthcare provider about this medicine before receiving any vaccine.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in the original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight and moisture
❌ DON'T
Do not store in the bathroom cabinet
✈️ Traveling with This Medicine
When traveling, carry this medicine in its original packaging with a copy of your prescription. Keep it in your carry-on luggage to avoid loss or temperature extremes. If crossing time zones, consult your doctor about adjusting the dosing schedule. Store at room temperature and avoid leaving it in hot cars or direct sunlight. Check customs regulations for carrying prescription medicines to your destination.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: This medicine starts lowering blood pressure within a few hours, but the full effect may take 1-2 weeks. It is important to take it regularly as prescribed.
A: It is usually recommended to take it in the morning to avoid frequent urination at night. However, follow your doctor's advice.
A: If you remember within 12 hours, take the missed dose. If more than 12 hours have passed, skip it and continue with your regular schedule. Do not double dose.
A: No, do not stop without consulting your doctor. Blood pressure may rise again, and sudden withdrawal can cause serious heart problems.
A: It can affect kidney function, so regular monitoring is needed. Inform your doctor if you have kidney disease.
🤔 Common Patient Concerns
🛑 Myths vs. Facts
- Myth: This medicine can cure high blood pressure permanently.
Fact: This medicine helps control blood pressure but does not cure hypertension. Lifestyle changes and ongoing medication are usually needed. - Myth: You can stop taking this medicine once your blood pressure is normal.
Fact: Blood pressure may remain normal only as long as you take the medicine. Stopping suddenly can cause a dangerous rise in blood pressure or heart problems. - Myth: This medicine causes kidney damage in everyone.
Fact: While indapamide can affect kidney function, regular monitoring helps prevent serious issues. Many patients take it safely for years.
🔄 Alternative Options
Generic Alternatives
- Atenolol 50 mg + Indapamide 1.5 mg tablet (generic)