ibstatin a 10mg/150mg capsule - Rosuvastatin (10mg) + Aspirin (150mg) medicine

Athrovas ASP 10mg/150mg Capsule: Complete Medicine Guide

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🏭 Indiabulls pharmaceutical ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Sep 26, 2026
⚠️ Hepatotoxicity Risk ⚠️ Nephrotoxicity Risk 🤰 Pregnancy Category Not recommended during pregnancy. Rosuvastatin is contraindicated in pregnancy due to potential harm to the fetus. Aspirin may cause premature closure of ductus arteriosus and other fetal risks. 📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Well-established for individual components; combination evidence is limited.
Reviewed by
SaathiMed Expert Panel | Sep 26, 2026
🩺
Medically Fact-Checked & Clinically Verified by SaathiMed Clinical Review Board
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026

When to Call Your Doctor IMMEDIATELY

  • Blood in stool or vomit
  • Severe abdominal pain
  • Chest pain or difficulty breathing
  • Severe headache with visual changes
  • Sudden swelling of face, lips, or throat
  • Yellowing of skin or eyes
  • Decreased urine output
  • Severe muscle pain or weakness

If experiencing severe symptoms, call emergency services immediately.

What is ibstatin a 10mg/150mg capsule used for?

This medicine is a combination of Rosuvastatin and Aspirin used to lower cholesterol and prevent blood clots in patients at risk of heart attack or stroke. It is taken once daily with food.

  • Generic Name: Rosuvastatin (10mg) + Aspirin (150mg)
  • Manufacturer: Indiabulls pharmaceutical ltd
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 ibstatin a 10mg/150mg capsule के बारे में (Hindi Summary)

उपयोग: यह दवा रोसुवास्टेटिन और एस्पिरिन का संयोजन है, जिसका उपयोग कोलेस्ट्रॉल कम करने और दिल के दौरे या स्ट्रोक के जोखिम को कम करने के लिए किया जाता है। यह रक्त के थक्के बनने से रोकती है और हृदय की रक्षा करती है।

साइड इफेक्ट्स: आम दुष्प्रभावों में पेट में जलन, मतली, सिरदर्द, मांसपेशियों में दर्द और रक्तस्राव की प्रवृत्ति शामिल हैं। गंभीर दुष्प्रभावों में पेट या आंतों में रक्तस्राव, यकृत की समस्या, और मांसपेशियों का टूटना शामिल हो सकता है। किसी भी असामान्य लक्षण पर तुरंत डॉक्टर से संपर्क करें।

सुरक्षा सलाह: इस दवा को भोजन के साथ लें। शराब का सेवन न करें क्योंकि इससे रक्तस्राव और यकृत की समस्या का खतरा बढ़ता है। गर्भावस्था या स्तनपान के दौरान इसका उपयोग न करें। नियमित रूप से लिवर और किडनी की जांच कराएं। किसी भी असामान्य रक्तस्राव, चकत्ते, या मांसपेशियों में दर्द की सूचना तुरंत डॉक्टर को दें।

💡 Did You Know? India has the highest number of USFDA-compliant plants outside the USA.

💊 ibstatin a 10mg/150mg capsule Uses & Benefits

[{"condition":"Hypercholesterolemia and cardiovascular risk reduction","description":"Used to lower elevated LDL cholesterol and triglycerides while simultaneously reducing the risk of heart attack and stroke in patients with multiple risk factors.","evidence":"Well-established"},{"condition":"Secondary prevention of cardiovascular events","description":"Prescribed for patients with a history of myocardial infarction, ischemic stroke, or peripheral arterial disease to prevent recurrent events.","evidence":"Well-established"},{"condition":"Primary prevention in high-risk individuals","description":"May be used in patients with diabetes or multiple risk factors who require both lipid management and antiplatelet therapy.","evidence":"Established"}]

Off-label uses: [{"condition":"Prevention of preeclampsia","description":"Low-dose aspirin is sometimes used off-label for preeclampsia prevention, but this combination is not standard for that purpose.","evidence":"Limited"},{"condition":"Antiphospholipid syndrome","description":"Aspirin may be used off-label in antiphospholipid syndrome, but rosuvastatin is not typically included.","evidence":"Limited"}]

Primary treatment for: Cardiovascular risk reduction

Also treats: Hypercholesterolemia, Atherosclerosis, Coronary artery disease, Cerebrovascular disease

📋 Drug Information

Generic Name(s)Rosuvastatin (10mg) + Aspirin (150mg)
Brand Nameibstatin a 10mg/150mg capsule
ManufacturerIndiabulls pharmaceutical ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassCARDIAC
Action Class
Route of AdministrationOral
StorageStore at room temperature (15-30°C) in a dry place, away from direct sunlight and moisture.
Shelf Life24 months from the date of manufacture.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Take this medicine with food to reduce stomach upset.
2
Avoid alcohol while taking this medicine to prevent bleeding and liver issues.
3
Do not stop taking this medicine without consulting your doctor.
4
Report any unusual bleeding, bruising, or muscle pain immediately.
5
Regular monitoring of liver function, kidney function, and cholesterol levels is essential.
6
Inform your doctor if you are scheduled for any surgery or dental procedure.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅
High cholesterol
This medicine is commonly prescribed for this.
Likely Use
✅
History of heart attack
This medicine is used for secondary prevention.
Likely Use
❌
Fever
This medicine is not a primary fever reducer.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionRosuvastatin is absorbed orally, reaching peak plasma concentration in about 3-5 hours. Aspirin is rapidly absorbed from the stomach and upper intestine, with peak levels in 1-2 hours. Food may slightly delay absorption but does not significantly affect overall bioavailability.
DistributionRosuvastatin has a large volume of distribution and is taken up by the liver via organic anion transporting polypeptide 1B1. Aspirin is widely distributed throughout body tissues and crosses the placenta.
Protein BindingRosuvastatin is approximately 88% bound to plasma proteins, primarily albumin. Aspirin is about 80-90% bound to albumin, and its active metabolite salicylate is also highly protein-bound.
MetabolismRosuvastatin undergoes minimal metabolism, primarily by cytochrome P450 2C9, with some involvement of 2C19 and 3A4. Aspirin is rapidly hydrolyzed to salicylic acid in the liver and gastrointestinal tract.
Half-LifeRosuvastatin has an elimination half-life of approximately 19 hours. Aspirin has a half-life of 15-20 minutes, but its antiplatelet effect lasts for the lifespan of the platelet (7-10 days).
ExcretionRosuvastatin is excreted mainly unchanged in the feces (90%) and urine (10%). Aspirin metabolites are excreted primarily in the urine.
BioavailabilityRosuvastatin has an absolute bioavailability of about 20%. Aspirin has a bioavailability of approximately 50-75% due to first-pass metabolism.
Onset of ActionRosuvastatin begins to lower cholesterol within 1-2 weeks, with maximum effect in 4-6 weeks. Aspirin's antiplatelet effect begins within 30-60 minutes of ingestion.
Peak Plasma TimeRosuvastatin reaches peak plasma concentration in 3-5 hours. Aspirin reaches peak plasma concentration in 1-2 hours.
Duration of ActionRosuvastatin's lipid-lowering effect persists as long as the medicine is taken. Aspirin's antiplatelet effect lasts for the lifespan of the platelet, approximately 7-10 days.

How It Works

This medicine combines two active ingredients with distinct mechanisms. Rosuvastatin selectively inhibits HMG-CoA reductase, the rate-limiting enzyme in hepatic cholesterol synthesis, leading to upregulation of LDL receptors and increased clearance of LDL cholesterol from the blood. Aspirin irreversibly acetylates cyclooxygenase-1 (COX-1) in platelets, preventing the formation of thromboxane A2, a potent platelet aggregator and vasoconstrictor. The combined effect provides lipid lowering and antithrombotic action.

Mechanism Steps

1
HMG-CoA reductase inhibition: Rosuvastatin competitively inhibits HMG-CoA reductase in the liver, reducing cholesterol synthesis.
2
Upregulation of LDL receptors: Decreased intracellular cholesterol triggers increased expression of LDL receptors on hepatocytes, enhancing LDL clearance from circulation.
3
COX-1 acetylation: Aspirin irreversibly acetylates serine residue 529 in COX-1 within platelets, inhibiting the enzyme.
4
Thromboxane A2 suppression: Inhibition of COX-1 blocks the conversion of arachidonic acid to prostaglandin H2, thereby reducing thromboxane A2 production.
5
Platelet aggregation inhibition: Reduced thromboxane A2 levels impair platelet activation and aggregation, decreasing thrombus formation.

💡 How to Take ibstatin a 10mg/150mg capsule

Strength: Capsule containing Rosuvastatin 10 mg and Aspirin 150 mg.

1Take one capsule orally with a full glass of water.
2Take with food to reduce stomach upset.
3Swallow the capsule whole; do not crush or chew.
4Take at the same time each day.
5Do not take an extra dose if you miss one.

Dosage Information

Adult DosageThe usual adult dose is one capsule once daily, taken with food. The dose may be adjusted by your doctor based on your cholesterol levels, cardiovascular risk, and tolerance. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageElderly patients may be more sensitive to the effects of this medicine. Dose adjustment may be necessary based on renal and hepatic function. Consult your doctor.
Renal ImpairmentUse with caution in patients with renal impairment. Dose adjustment may be required. Consult your doctor.
Hepatic ImpairmentContraindicated in patients with severe liver disease. Use with caution in mild to moderate hepatic impairment. Dose adjustment may be necessary.
Maximum Daily DoseThe maximum recommended daily dose is one capsule (Rosuvastatin 10 mg + Aspirin 150 mg). Do not exceed the prescribed dose.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With food
Take with meals
Reduces stomach upset.
Grapefruit
Avoid
May increase drug levels.
Alcohol
Avoid
Increases risk of bleeding and liver problems.

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of ibstatin a 10mg/150mg capsule

✅ Common Side Effects

Stomach irritation or nausea (Common (5-10%))
Take with food or milk to reduce irritation. Consult doctor if persistent.
Headache (Common (5-10%))
Usually resolves on its own. Stay hydrated and rest.
Muscle aches (Common (5-10%))
Report to doctor if severe or accompanied by weakness.
Increased bleeding tendency (Common (5-10%))
Avoid activities that may cause injury. Report unusual bleeding.

🚨 Serious Side Effects

Gastrointestinal bleeding (Rare (<0.1%))
Seek immediate medical attention if you notice black stool, vomiting blood, or severe abdominal pain.
Rhabdomyolysis (Rare (<0.1%))
Report severe muscle pain, weakness, or dark urine immediately.
Hepatotoxicity (Rare (<0.1%))
Report yellowing of skin or eyes, dark urine, or right upper abdominal pain.
Severe allergic reaction (Rare (<0.1%))
Seek emergency care for swelling of face, lips, throat, or difficulty breathing.

⚠️ Rare Side Effects

Pancreatitis
Seek immediate medical attention for severe abdominal pain radiating to back.
Renal impairment
Report decreased urine output or swelling.
Interstitial lung disease
Report persistent cough or shortness of breath.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Warfarin Major
Methotrexate Major
Cyclosporine Major
Gemfibrozil Major
NSAIDs Moderate
ACE inhibitors Moderate
Fibrates Moderate
Antacids Minor
Oral contraceptives Minor
Digoxin Minor

🚨 Major Interactions

  • Warfarin
  • Methotrexate
  • Cyclosporine
  • Gemfibrozil

⚡ Moderate Interactions

  • NSAIDs
  • ACE inhibitors
  • Fibrates

🍷 Alcohol Interaction

Alcohol increases the risk of gastrointestinal bleeding and liver toxicity. It is advisable to avoid alcohol while taking this medicine.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Active bleeding or bleeding disorders","Severe liver disease","Aspirin-sensitive asthma","Pregnancy and breastfeeding","Hypersensitivity to rosuvastatin or aspirin","Children under 18 years"]

⚠️ Warnings & Precautions

["Avoid in patients with active peptic ulcer disease.","Use with caution in patients with renal impairment.","Monitor for signs of bleeding.","Avoid alcohol consumption.","Inform doctor before any surgery or dental procedure.","Do not use in patients with hereditary fructose intolerance."]

🤱 Lactation Safety

Not recommended during breastfeeding. Both rosuvastatin and aspirin are excreted in breast milk and may cause serious adverse reactions in the infant.

💊 Overdose Management

Overdose may cause severe gastrointestinal bleeding, liver damage, or muscle breakdown. Seek immediate medical attention. Treatment is supportive and symptomatic. There is no specific antidote for rosuvastatin; aspirin overdose may be treated with activated charcoal, gastric lavage, and supportive care.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for the next dose, skip the missed dose and continue with your regular schedule. Do not double dose.

Additional Safety Advice

General Safety

Take this medicine with food to reduce stomach upset. Avoid alcohol as it increases the risk of gastrointestinal bleeding and liver problems. Do not take this medicine if you are pregnant or planning to become pregnant. Inform your doctor about all other medicines you are taking, especially blood thinners, NSAIDs, and certain antibiotics. Regular monitoring of liver function, kidney function, and cholesterol levels is necessary. Report any unusual bleeding, bruising, muscle pain, or dark urine immediately.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients may be more sensitive to the effects of this medicine. Dose adjustment may be necessary based on renal and hepatic function. Regular monitoring is advised.

🤰 Pregnancy Planning (TTC)

This medicine is not recommended during pregnancy or when planning pregnancy. Consult your doctor for alternative treatments.

🏥 Post-Surgery Considerations

Inform your surgeon about this medicine before any surgery. It may need to be stopped temporarily due to bleeding risk.

🦷 Dental Procedures

Inform your dentist about this medicine before any dental procedure. It may increase bleeding during dental work.

💚 Lifestyle Tips for Better Results

🏃
Maintain a healthy weight to reduce cardiovascular risk.
🥗
Regular low-impact exercise like walking or swimming.
😴
Practice good posture.
💧
Include anti-inflammatory foods in your diet.
🧘
Get adequate sleep.
🌞
Manage stress through relaxation techniques.

🏋️ Exercise Considerations

Avoid contact sports or activities that may cause injury due to increased bleeding risk. Consult your doctor before starting any new exercise regimen.

🥗 Diet Recommendations

Include omega-3 rich foods
Reduce processed food intake
Stay well hydrated
Limit saturated and trans fats
Increase fiber intake

💼 Impact on Daily Work & Life

This medicine may cause dizziness or fatigue in some individuals. Avoid driving or operating heavy machinery if you experience these symptoms.

🛑 When to Stop This Medicine

Do not stop this medicine without consulting your doctor. Stopping suddenly may increase the risk of cardiovascular events. Your doctor may adjust or stop the medicine based on your condition.

📅 Long-Term Use Effects

Long-term use requires regular monitoring of liver function, kidney function, and lipid levels. It may increase the risk of bleeding and muscle problems. Do not stop without consulting your doctor.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Lifestyle modifications

Diet and exercise can complement medicine for cardiovascular risk reduction.

Evidence: Well-established
Other statins

Atorvastatin or simvastatin may be alternatives if rosuvastatin is not tolerated.

Evidence: Well-established

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

No specific vaccine interactions are established. However, inform your doctor about this medicine before any vaccination.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

Carry this medicine in its original packaging with a copy of your prescription. Store at room temperature and avoid extreme heat or moisture. If traveling across time zones, adjust the timing of your dose gradually. Check customs regulations for carrying prescription medicines.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 55-year-old man with a history of heart attack
He was prescribed this medicine after a heart attack. He took it regularly with food and avoided alcohol. His cholesterol levels improved, and he did not experience any recurrent cardiac events. He emphasized the importance of regular follow-ups.
💡 Lesson: Consistency with prescribed dose and lifestyle modifications significantly improve outcomes.
👤 A 62-year-old woman with diabetes and high cholesterol
She started this medicine to manage her cholesterol and reduce cardiovascular risk. She experienced mild stomach irritation initially, which subsided after taking it with food. She reported no bleeding episodes and her lipid profile improved.
💡 Lesson: Taking the medicine with food can minimize gastrointestinal side effects.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: Rosuvastatin starts lowering cholesterol within 1-2 weeks, with maximum effect in 4-6 weeks. Aspirin's antiplatelet effect begins within 30-60 minutes.

Q: Can I take this medicine without food?

A: It is recommended to take this medicine with food to reduce stomach upset.

Q: What should I do if I miss a dose?

A: Take it as soon as you remember. If it is almost time for the next dose, skip the missed dose and continue with your regular schedule. Do not double dose.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my kidney function?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?

🔄 Substitutes for ibstatin a 10mg/150mg capsule

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: This medicine can be taken without a prescription.
    Fact: This medicine is a prescription drug and should only be taken under medical supervision.
  • Myth: It is safe to drink alcohol while taking this medicine.
    Fact: Alcohol increases the risk of bleeding and liver problems; it should be avoided.
  • Myth: This medicine can be stopped once cholesterol levels are normal.
    Fact: It should be continued as prescribed to maintain cardiovascular protection.

🔄 Alternative Options

Generic Alternatives

  • Rosuvastatin 10 mg + Aspirin 150 mg capsule

📊 Comparison with Similar Medicines

[{"medicine":"This medicine","composition":"Rosuvastatin 10 mg + Aspirin 150 mg","dosage_form":"Capsule","frequency":"Once daily"},{"medicine":"Atorvastatin + Aspirin","composition":"Atorvastatin 10 mg + Aspirin 75 mg","dosage_form":"Capsule","frequency":"Once daily"}]

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