ibolme ct ld 20mg/6.25mg tablet - Olmesartan Medoxomil (20mg) + Chlorthalidone (6.25mg) medicine

Biolsar 20 Tablet: Complete Guide to Uses, Side Effects, and Safety

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🏭 Indiabulls pharmaceutical ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Sep 26, 2026
⚠️ Nephrotoxicity Risk 🤰 Pregnancy Category Not recommended. This medicine can cause fetal harm, especially in the second and third trimesters. Use effective contraception and consult your doctor if you are pregnant or planning to become pregnant. 📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Well-established for hypertension.
Reviewed by
SaathiMed Expert Panel | Sep 26, 2026
🩺
Medically Fact-Checked & Clinically Verified by SaathiMed Clinical Review Board
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026

When to Call Your Doctor IMMEDIATELY

  • Severe dizziness or fainting
  • Decreased urine output or swelling in legs
  • Irregular heartbeat or palpitations
  • Muscle weakness or cramps
  • Swelling of face, lips, or throat
  • Severe abdominal pain
  • Yellowing of skin or eyes

If experiencing severe symptoms, call emergency services immediately.

What is ibolme ct ld 20mg/6.25mg tablet used for?

This medicine is a combination of Olmesartan Medoxomil 20 mg and Chlorthalidone 6.25 mg used to treat high blood pressure. It works by relaxing blood vessels and removing excess fluid. Take it once daily as prescribed.

  • Generic Name: Olmesartan Medoxomil (20mg) + Chlorthalidone (6.25mg)
  • Manufacturer: Indiabulls pharmaceutical ltd
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 ibolme ct ld 20mg/6.25mg tablet के बारे में (Hindi Summary)

उपयोग: यह दवा उच्च रक्तचाप (हाइपरटेंशन) के इलाज के लिए इस्तेमाल की जाती है। यह ओल्मेसार्टन मेडोक्सोमिल और क्लोर्थालिडोन का संयोजन है। यह रक्त वाहिकाओं को आराम देकर और शरीर से अतिरिक्त नमक और पानी को बाहर निकालकर रक्तचाप को कम करती है। यह दवा स्ट्रोक, दिल के दौरे और गुर्दे की समस्याओं के जोखिम को कम करने में मदद करती है। इसे डॉक्टर के निर्देशानुसार ही लें।

साइड इफेक्ट्स: आम दुष्प्रभावों में चक्कर आना, सिरदर्द, थकान और बार-बार पेशाब आना शामिल हैं। गंभीर दुष्प्रभाव दुर्लभ हैं लेकिन इनमें गंभीर निर्जलीकरण, इलेक्ट्रोलाइट असंतुलन, गुर्दे की समस्या, एलर्जी और बहुत कम रक्तचाप शामिल हो सकते हैं। यदि आपको मांसपेशियों में कमजोरी, अनियमित दिल की धड़कन या सूजन महसूस हो तो तुरंत डॉक्टर से संपर्क करें।

सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। डॉक्टर से पूछे बिना दवा बंद या मात्रा न बदलें। पर्याप्त पानी पिएं, खासकर गर्म मौसम में। शराब से बचें क्योंकि इससे चक्कर और कम रक्तचाप बढ़ सकता है। धीरे-धीरे उठें ताकि गिरने से बचें। यदि आपको गुर्दे या लीवर की बीमारी, मधुमेह या गाउट है तो डॉक्टर को बताएं। नियमित रूप से गुर्दे की कार्यप्रणाली और इलेक्ट्रोलाइट्स की जांच कराएं। गर्भावस्था में यह दवा नुकसानदायक हो सकती है, इसलिए गर्भनिरोधक का उपयोग करें और गर्भवती होने पर डॉक्टर को बताएं।

💡 Did You Know? India is the largest provider of generic medicines globally, supplying over 50% of global vaccine demand.

💊 ibolme ct ld 20mg/6.25mg tablet Uses & Benefits

[{"condition":"Hypertension","description":"Used to lower high blood pressure when monotherapy is insufficient, reducing cardiovascular and renal risk.","evidence":"Well-established"}]

Off-label uses: []

Primary treatment for: Hypertension

Also treats: Heart failure, Diabetic nephropathy, Stroke prevention

📋 Drug Information

Generic Name(s)Olmesartan Medoxomil (20mg) + Chlorthalidone (6.25mg)
Brand Nameibolme ct ld 20mg/6.25mg tablet
ManufacturerIndiabulls pharmaceutical ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassCARDIAC
Action Class
Route of AdministrationOral
StorageStore at room temperature (15-30°C) in a dry place, away from direct sunlight. Keep in the original container.
Shelf Life24 months from the date of manufacture.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Take this medicine at the same time each day to maintain consistent blood pressure control.
2
Monitor your blood pressure regularly and keep a record to share with your doctor.
3
Stay well hydrated, especially during hot weather or exercise, to prevent dehydration.
4
Avoid alcohol as it can increase dizziness and low blood pressure.
5
Report any muscle cramps, weakness, or irregular heartbeat to your doctor promptly.
6
Do not stop this medicine abruptly without consulting your doctor.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅
High blood pressure
This medicine is commonly prescribed for this.
Likely Use
❌
Swelling in legs
This medicine is not a primary treatment for edema.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionOlmesartan medoxomil is rapidly absorbed after oral administration, with peak plasma concentration reached in 1-2 hours. Chlorthalidone is absorbed slowly from the gastrointestinal tract, with peak levels at about 2-6 hours. Food does not significantly affect absorption.
DistributionOlmesartan is highly protein-bound (99%) and has a volume of distribution of about 17 L. Chlorthalidone is extensively bound to red blood cells and plasma proteins, with a large volume of distribution.
Protein BindingOlmesartan: 99% bound to plasma proteins. Chlorthalidone: approximately 75% bound to plasma proteins and 90% to red blood cells.
MetabolismOlmesartan medoxomil is hydrolyzed to active olmesartan during absorption and is not further metabolized to a significant extent. Chlorthalidone is not metabolized and is excreted unchanged.
Half-LifeOlmesartan: approximately 13 hours. Chlorthalidone: approximately 40-60 hours.
ExcretionOlmesartan is excreted mainly in feces (via bile) and urine. Chlorthalidone is excreted primarily unchanged in urine.
BioavailabilityOlmesartan medoxomil: approximately 26%. Chlorthalidone: approximately 65%.
Onset of ActionBlood pressure lowering begins within 1-2 weeks, with maximal effect after 4-8 weeks.
Peak Plasma TimeOlmesartan: 1-2 hours. Chlorthalidone: 2-6 hours.
Duration of ActionOlmesartan: 24 hours. Chlorthalidone: 24-72 hours.

How It Works

Olmesartan medoxomil blocks angiotensin II type 1 (AT1) receptors, preventing angiotensin II from causing vasoconstriction and aldosterone release, thereby lowering blood pressure. Chlorthalidone inhibits sodium reabsorption in the distal convoluted tubule, increasing excretion of sodium, chloride, and water, which reduces plasma volume and peripheral resistance. Together they provide complementary blood pressure reduction.

Mechanism Steps

1
AT1 receptor blockade: Olmesartan medoxomil is hydrolyzed to olmesartan, which selectively blocks AT1 receptors, preventing angiotensin II-mediated vasoconstriction and aldosterone secretion.
2
Reduced aldosterone: Decreased aldosterone leads to less sodium and water retention, lowering blood volume and blood pressure.
3
Diuretic action: Chlorthalidone inhibits the thiazide-sensitive sodium-chloride cotransporter in the distal convoluted tubule, increasing excretion of sodium, chloride, and water.
4
Combined effect: The combination produces additive blood pressure reduction through complementary mechanisms.

💡 How to Take ibolme ct ld 20mg/6.25mg tablet

Strength: Tablet containing Olmesartan Medoxomil 20 mg and Chlorthalidone 6.25 mg.

1Take one tablet by mouth once daily, with or without food.
2Swallow the tablet whole with a glass of water.
3Take it at the same time each day to maintain consistent levels.
4If you have trouble swallowing, consult your doctor before crushing the tablet.
5Do not stop taking this medicine without consulting your doctor.

Dosage Information

Adult DosageThe usual adult dose is one tablet once daily, taken orally with or without food. The dose may be adjusted by your doctor based on your blood pressure response and tolerability. Do not exceed the recommended dose. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageElderly patients may be more sensitive to the blood pressure-lowering effects. Start with a lower dose and monitor closely for dizziness and falls. Dose must be individualized by a qualified clinician.
Renal ImpairmentIn patients with mild to moderate renal impairment, no dose adjustment is usually needed, but monitor kidney function and electrolytes. In severe renal impairment (eGFR <30 mL/min/1.73 m2), use is not recommended. Dose must be individualized by a qualified clinician.
Hepatic ImpairmentIn patients with mild to moderate hepatic impairment, no dose adjustment is usually needed. In severe hepatic impairment, use is not recommended. Dose must be individualized by a qualified clinician.
Maximum Daily DoseOne tablet (Olmesartan 20 mg + Chlorthalidone 6.25 mg) once daily. Do not exceed the dose prescribed by your doctor.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With or without food
Take at the same time daily
Food does not significantly affect absorption.
High-sodium foods
Limit intake
High sodium can counteract blood pressure lowering.
Alcohol
Avoid
May increase dizziness and low blood pressure.

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of ibolme ct ld 20mg/6.25mg tablet

✅ Common Side Effects

Dizziness (Common (5-10%))
Rise slowly from sitting or lying position. Avoid driving if dizzy.
Headache (Common (5-10%))
Usually resolves. Take paracetamol if needed, but consult doctor if persistent.
Fatigue (Common (5-10%))
Ensure adequate rest and hydration. Consult doctor if severe.
Increased urination (Common (5-10%))
Take dose earlier in the day to avoid nighttime urination.

🚨 Serious Side Effects

Severe hypotension (Rare (<0.1%))
Seek immediate medical attention if you feel faint or have very low blood pressure.
Electrolyte imbalance (Uncommon (0.1-1%))
Report muscle cramps, weakness, or irregular heartbeat to your doctor.
Acute kidney injury (Rare (<0.1%))
Seek medical help if you notice decreased urine output or swelling.
Angioedema (Rare (<0.1%))
Stop the medicine and seek emergency care if you experience swelling of face, lips, or throat.

⚠️ Rare Side Effects

Pancreatitis
Seek immediate medical attention if you have severe abdominal pain.
Severe skin reactions
Stop the medicine and seek emergency care if you develop a rash with blisters or peeling skin.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Lithium Major
NSAIDs Major
Corticosteroids Moderate
Digoxin Moderate
Oral hypoglycemics Moderate
Antacids Minor

🚨 Major Interactions

  • Lithium
  • NSAIDs
  • Other diuretics

⚡ Moderate Interactions

  • Corticosteroids
  • Digoxin
  • Oral hypoglycemics

🍷 Alcohol Interaction

Alcohol may enhance the blood pressure-lowering effect and increase the risk of dizziness, fainting, and falls. It is advisable to avoid alcohol while taking this medicine.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Pregnancy","Anuria","Hypersensitivity to olmesartan, chlorthalidone, or sulfonamide-derived drugs","Severe renal impairment (eGFR

⚠️ Warnings & Precautions

["May cause symptomatic hypotension, especially in volume-depleted patients.","Monitor electrolytes regularly; hypokalemia may occur.","May worsen renal function; monitor kidney function.","Can cause dizziness; avoid driving or operating machinery until you know how it affects you.","Not recommended during pregnancy; can cause fetal harm.","May increase uric acid levels and precipitate gout.","May cause photosensitivity; use sun protection."]

🤱 Lactation Safety

It is not known whether olmesartan or chlorthalidone are excreted in human breast milk. Because of the potential for serious adverse reactions in nursing infants, a decision should be made whether to discontinue nursing or discontinue the medicine, taking into account the importance of the medicine to the mother.

💊 Overdose Management

Overdose may cause severe hypotension, electrolyte imbalance, and dehydration. Treatment is supportive and symptomatic. If overdose is suspected, contact a poison control center or emergency room immediately. Induce vomiting only if advised by a healthcare professional. Monitor vital signs and electrolytes closely.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up.

Additional Safety Advice

General Safety

Take this medicine exactly as prescribed. Do not stop or change the dose without consulting your doctor. Drink enough water to stay hydrated, especially in hot weather or during exercise. Avoid alcohol as it can worsen dizziness and low blood pressure. Stand up slowly to prevent falls. Inform your doctor if you have kidney or liver disease, diabetes, or gout. Regular blood tests for kidney function and electrolytes are important. This medicine can harm an unborn baby; use effective contraception and tell your doctor if you plan to become pregnant or are pregnant.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients may be more sensitive to the blood pressure-lowering effects and are at higher risk of dizziness and falls. Start with a lower dose and monitor closely.

🤰 Pregnancy Planning (TTC)

This medicine is not recommended during pregnancy as it can harm the unborn baby. Use effective contraception while taking this medicine. If you plan to become pregnant, consult your doctor to switch to a safer alternative.

🏥 Post-Surgery Considerations

Inform your surgeon and anesthesiologist that you are taking this medicine. It may need to be temporarily stopped before surgery to prevent low blood pressure during the procedure.

🦷 Dental Procedures

Inform your dentist that you are taking this medicine. It may cause dry mouth or dizziness during dental procedures. Maintain good oral hygiene.

💚 Lifestyle Tips for Better Results

🏃
Maintain a healthy weight to help control blood pressure.
🥗
Engage in regular physical activity like walking or swimming.
😴
Reduce salt intake to less than 5 grams per day.
💧
Eat a balanced diet rich in fruits and vegetables.
🧘
Avoid smoking and limit alcohol consumption.
🌞
Manage stress through relaxation techniques.

🏋️ Exercise Considerations

Exercise is generally safe, but avoid strenuous activity in hot weather to prevent dehydration. Stay hydrated and monitor for dizziness.

🥗 Diet Recommendations

Follow a low-sodium diet.
Include potassium-rich foods like bananas and oranges, unless advised otherwise.
Limit processed and fried foods.
Stay well hydrated.

💼 Impact on Daily Work & Life

This medicine may cause dizziness, especially when standing up quickly. Avoid driving or operating heavy machinery until you know how it affects you. Take breaks and stay hydrated during work.

🛑 When to Stop This Medicine

Do not stop this medicine without consulting your doctor. If you experience severe side effects, contact your doctor immediately. Your doctor may adjust the dose or switch to another medicine.

📅 Long-Term Use Effects

Long-term use may lead to electrolyte imbalances, kidney function changes, and increased uric acid levels. Regular monitoring of blood pressure, kidney function, and electrolytes is essential. Do not stop the medicine without consulting your doctor.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Lifestyle modifications

Diet, exercise, and weight loss can help lower blood pressure.

Evidence: Well-established
Other antihypertensive classes

ACE inhibitors, calcium channel blockers, or beta-blockers may be alternatives.

Evidence: Well-established

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

No specific vaccine interactions are known. Continue routine vaccinations as recommended by your doctor.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

Carry this medicine in its original packaging with a copy of your prescription. Store at room temperature and protect from moisture. If traveling across time zones, take your dose at the usual local time. Keep enough supply for the entire trip. Check customs regulations for carrying prescription medicines.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 55-year-old man with hypertension not controlled on a single medicine.
He was prescribed this medicine once daily. After 4 weeks, his blood pressure improved significantly. He experienced mild dizziness initially, which resolved after a few days. He was advised to drink plenty of water and avoid alcohol.
💡 Lesson: Combination therapy can effectively control blood pressure when monotherapy fails. Adherence and lifestyle changes are key.
👤 A 62-year-old woman with diabetes and hypertension.
She started this medicine and noticed increased urination. Her doctor adjusted the timing to morning to avoid sleep disturbance. Regular monitoring showed stable kidney function and electrolytes.
💡 Lesson: Taking the medicine earlier in the day can reduce nighttime urination. Regular monitoring is essential for safety.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: Blood pressure begins to lower within 1-2 weeks, with maximal effect after 4-8 weeks.

Q: Can I take this medicine with food?

A: Yes, you can take it with or without food. Taking it at the same time daily is important.

Q: What should I do if I miss a dose?

A: If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my kidney function?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?

🔄 Substitutes for ibolme ct ld 20mg/6.25mg tablet

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: This medicine can be stopped once blood pressure is normal.
    Fact: High blood pressure often has no symptoms and requires long-term treatment. Stopping suddenly can cause dangerous increases in blood pressure.
  • Myth: This medicine damages the kidneys.
    Fact: When used appropriately, this medicine can protect kidney function, especially in diabetes. Regular monitoring is important.

🔄 Alternative Options

Generic Alternatives

  • Olmesartan Medoxomil + Chlorthalidone (generic)

Brand Alternatives

  • Olmetor-CH 20 Tablet
  • Olmesar-CH 20 Tablet
  • Olmat-CH 20 Tablet

📊 Comparison with Similar Medicines

[{"medicine":"Olmesartan + Chlorthalidone","class":"ARB + Thiazide-like diuretic","usual_dose":"Once daily","notes":"Effective for hypertension; monitor electrolytes."},{"medicine":"Telmisartan + Chlorthalidone","class":"ARB + Thiazide-like diuretic","usual_dose":"Once daily","notes":"Similar efficacy; may have different side effect profile."}]

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