Acebact 375mg Tablet: Complete Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Difficulty breathing or swelling of face, lips, or throat
- Severe or persistent diarrhea, or blood in stool
- Yellowing of skin or eyes
- Severe abdominal pain
- Decreased urine output
- Unusual bleeding or bruising
- Seizures
If experiencing severe symptoms, call emergency services immediately.
What is hyfact 375mg tablet used for?
This medicine is an antibiotic containing sultamicillin, used to treat bacterial infections of the respiratory tract, urinary tract, skin, and teeth. It works by killing bacteria and is available only by prescription.
- Generic Name: Sultamicillin tosilate (375mg)
- Manufacturer: Aarsh Remedies Pvt Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 hyfact 375mg tablet के बारे में (Hindi Summary)
उपयोग: यह दवा एक एंटीबायोटिक है जिसका उपयोग बैक्टीरियल संक्रमणों के इलाज के लिए किया जाता है, जैसे कि श्वसन तंत्र, मूत्र मार्ग, त्वचा और दांतों के संक्रमण। यह बैक्टीरिया को मारकर काम करती है।
साइड इफेक्ट्स: आम दुष्प्रभावों में दस्त, जी मिचलाना, उल्टी, पेट दर्द और त्वचा पर चकत्ते शामिल हैं। गंभीर दुष्प्रभाव दुर्लभ हैं लेकिन एलर्जी प्रतिक्रिया या गंभीर दस्त हो सकते हैं। किसी भी गंभीर लक्षण पर तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: इस दवा को डॉक्टर के निर्देशानुसार ही लें। खाने के साथ लें ताकि पेट खराब न हो। पूरा कोर्स पूरा करें, चाहे आप बेहतर महसूस करें। शराब से बचें। गुर्दे या यकृत की समस्या हो तो डॉक्टर को बताएं।
💊 hyfact 375mg tablet Uses & Benefits
[{"condition":"Upper respiratory tract infections","description":"Used to treat bacterial infections such as sinusitis, pharyngitis, and tonsillitis caused by susceptible organisms.","evidence":"Well-established"},{"condition":"Lower respiratory tract infections","description":"Effective against community-acquired pneumonia and acute exacerbations of chronic bronchitis caused by susceptible bacteria.","evidence":"Well-established"},{"condition":"Urinary tract infections","description":"Treats uncomplicated and complicated urinary tract infections caused by susceptible strains of bacteria.","evidence":"Well-established"},{"condition":"Skin and soft tissue infections","description":"Used for cellulitis, abscesses, and wound infections caused by susceptible bacteria.","evidence":"Well-established"},{"condition":"Dental infections","description":"Effective against dental abscesses and periodontal infections caused by susceptible oral bacteria.","evidence":"Well-established"}]
Off-label uses: [{"condition":"Gonorrhea","description":"Sometimes used off-label for uncomplicated gonorrhea, but resistance patterns may limit effectiveness.","evidence":"Limited"}]
Primary treatment for: Bacterial infections
Also treats: Respiratory tract infections, Urinary tract infections, Skin infections, Dental infections
📋 Drug Information
| Generic Name(s) | Sultamicillin tosilate (375mg) |
| Brand Name | hyfact 375mg tablet |
| Manufacturer | Aarsh Remedies Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | ANTI INFECTIVES |
| Action Class | Ampicillin & Sulbactam ester compound |
| Route of Administration | Oral |
| Storage | Store at room temperature between 15°C and 30°C (59°F to 86°F). Keep in a dry place, away from direct sunlight and moisture. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine contains sultamicillin, a mutual prodrug that is hydrolyzed in the body to release ampicillin and sulbactam in a 1:1 molar ratio. Ampicillin is a beta-lactam antibiotic that inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins (PBPs), leading to bacterial cell lysis and death. Sulbactam is a beta-lactamase inhibitor that irreversibly binds to certain beta-lactamase enzymes produced by bacteria, preventing them from degrading ampicillin. This combination extends the spectrum of ampicillin to include beta-lactamase-producing strains of bacteria.
Mechanism Steps
💡 How to Take hyfact 375mg tablet
Strength: Sultamicillin tosilate 375 mg immediate-release tablet.
Dosage Information
| Adult Dosage | The usual adult dose of this medicine is 375 mg to 750 mg taken orally twice daily, depending on the type and severity of the infection. For severe infections, higher doses may be prescribed. The duration of treatment varies from 5 to 14 days, depending on the infection. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician for appropriate dosing in children. |
| Elderly Dosage | Elderly patients may have reduced renal function and may require dose adjustment. Monitor renal function and adjust dose accordingly. |
| Renal Impairment | In patients with renal impairment (creatinine clearance less than 30 mL/min), the dose should be reduced or the dosing interval extended. Consult a clinician for specific adjustments. |
| Hepatic Impairment | No specific dose adjustment is recommended for hepatic impairment, but monitor liver function closely. |
| Maximum Daily Dose | The maximum recommended daily dose is 1500 mg (as sultamicillin) in divided doses, but this may vary based on the severity of infection and renal function. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of hyfact 375mg tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | |
| Methotrexate | Major | |
| Allopurinol | Major | |
| Oral contraceptives | Moderate | |
| Probenecid | Moderate | |
| Tetracyclines | Moderate | |
| Antacids | Minor |
🚨 Major Interactions
- Warfarin
- Methotrexate
- Allopurinol
⚡ Moderate Interactions
- Oral contraceptives
- Probenecid
- Tetracyclines
🍷 Alcohol Interaction
Alcohol may worsen stomach side effects such as nausea and vomiting. It is advisable to avoid alcohol while taking this medicine.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Hypersensitivity to penicillins, cephalosporins, or sulbactam","History of severe allergic reaction to beta-lactam antibiotics","Infectious mononucleosis (increased risk of rash)","Severe renal impairment without dose adjustment"]
⚠️ Warnings & Precautions
["Serious allergic reactions can occur. Discontinue immediately if signs of anaphylaxis appear.","Clostridioides difficile-associated diarrhea may occur. Use with caution in patients with gastrointestinal disease.","Prolonged use may lead to bacterial or fungal superinfections.","Dose adjustment is required in patients with renal impairment.","May reduce effectiveness of oral contraceptives; use additional contraception.","Not effective against viral infections."]
🤱 Lactation Safety
Ampicillin and sulbactam are excreted in breast milk. Use with caution in nursing mothers. Monitor infant for diarrhea or thrush.
💊 Overdose Management
Overdose may cause nausea, vomiting, diarrhea, and electrolyte imbalance. Treatment is symptomatic and supportive. In severe cases, hemodialysis may be considered to remove ampicillin and sulbactam from the blood. Contact a poison control center or emergency department immediately if overdose is suspected.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up.
Additional Safety Advice
Take this medicine exactly as prescribed by your doctor. Do not skip doses or stop treatment early, even if you feel better, as this can lead to antibiotic resistance. Take this medicine with food to reduce stomach upset. Drink plenty of water throughout the day. Avoid alcohol while taking this medicine, as it may worsen stomach side effects. Inform your doctor if you have kidney or liver problems, or if you are allergic to penicillin or other antibiotics. Do not share this medicine with others. If you experience severe diarrhea, rash, or difficulty breathing, seek medical help immediately. Complete the full course as prescribed.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients may have reduced renal function and may require dose adjustment. Monitor renal function closely.
🤰 Pregnancy Planning (TTC)
If you are planning pregnancy, consult your doctor before taking this medicine. It is generally considered safe but use only if clearly needed.
🏥 Post-Surgery Considerations
This medicine may be prescribed to prevent or treat surgical site infections. Follow your surgeon's instructions.
🦷 Dental Procedures
This medicine may be prescribed before or after dental procedures to prevent or treat infection. Inform your dentist if you are taking it.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
No specific exercise restrictions, but if you feel dizzy or weak, avoid strenuous activities until you feel better.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause dizziness in some people. If affected, avoid driving or operating heavy machinery until you know how it affects you.
🛑 When to Stop This Medicine
Do not stop this medicine without consulting your doctor. Complete the full course as prescribed, even if you feel better. If you experience severe side effects, contact your doctor immediately.
📅 Long-Term Use Effects
Long-term use of this medicine may lead to antibiotic resistance and superinfections. It is generally prescribed for short courses. Prolonged use should be monitored by a clinician.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Another antibiotic combination that may be used for similar infections.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
No specific vaccine interactions reported. Continue routine vaccinations as scheduled.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
Carry this medicine in its original packaging with a copy of your prescription. Store at room temperature and protect from moisture. If traveling across time zones, adjust dosing times gradually. Check customs regulations for carrying antibiotics.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: You may start feeling better within 2-3 days, but you must complete the full course as prescribed.
A: Yes, take it with food to reduce stomach upset.
A: Take it as soon as you remember, but if it's almost time for your next dose, skip the missed dose. Do not double dose.
🤔 Common Patient Concerns
🔄 Substitutes for hyfact 375mg tablet
View AllAlternative brands with exact same active ingredient:
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myclin 375mg tabletJabs Biotech Pvt Ltd ₹77.00 79.5% CHEAPER
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betamp 375mg tabletTorrent Pharmaceuticals Ltd ₹170.00 54.7% CHEAPER
-
ampirok 375mg tabletAstrum Healthcare Pvt Ltd ₹174.10 53.6% CHEAPER
-
sulbage 375mg tabletAllenge India ₹192.00 48.8% CHEAPER
-
Talmic 375mg TabletAssociated Biopharma ₹230.00 38.7% CHEAPER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: Antibiotics can cure viral infections like the common cold.
Fact: This medicine is effective only against bacterial infections and will not treat viral infections. - Myth: You can stop taking antibiotics once you feel better.
Fact: You must complete the full course as prescribed to prevent recurrence and antibiotic resistance.
🔄 Alternative Options
Generic Alternatives
- Sultamicillin tosilate 375 mg tablet
Brand Alternatives
- Acebact 375mg tablet