hiril 5mg tablet - Enalapril (5mg) medicine

Envas 5 Tablet (Enalapril 5 mg): Complete Medicine Guide

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🏭 Hinglaj Laboratories 📦 Varies by brand 💊 Allopathy 📅 Updated: Sep 26, 2026
⚠️ Nephrotoxicity Risk 🤰 Pregnancy Category This medicine is contraindicated in pregnancy. It can cause fetal harm, including oligohydramnios, fetal renal failure, and death. Women of childbearing potential should use effective contraception. If pregnancy is detected, discontinue this medicine immediately and consult a doctor. 📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: High
Reviewed by
SaathiMed Expert Panel | Sep 26, 2026
🩺
Medically Fact-Checked & Clinically Verified by SaathiMed Clinical Review Board
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026

When to Call Your Doctor IMMEDIATELY

  • Swelling of the face, lips, throat, or tongue
  • Difficulty breathing or swallowing
  • Severe dizziness or fainting
  • Decreased urine output or swelling in legs
  • Irregular heartbeat or palpitations
  • Severe abdominal pain
  • Yellowing of skin or eyes

If experiencing severe symptoms, call emergency services immediately.

What is hiril 5mg tablet used for?

This medicine contains Enalapril 5 mg, an ACE inhibitor used to treat high blood pressure and heart failure. It works by relaxing blood vessels to lower blood pressure and reduce the heart's workload. It is taken orally, usually once or twice daily.

  • Generic Name: Enalapril (5mg)
  • Manufacturer: Hinglaj Laboratories
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 hiril 5mg tablet के बारे में (Hindi Summary)

उपयोग: यह दवा एनालाप्रिल 5 मिलीग्राम युक्त है और मुख्य रूप से उच्च रक्तचाप (हाइपरटेंशन) और हृदय विफलता के इलाज के लिए उपयोग की जाती है। यह रक्त वाहिकाओं को आराम देकर रक्तचाप को कम करती है और हृदय पर दबाव कम करती है। यह दवा दिल के दौरे के बाद जीवन रक्षा दर को बढ़ाने और कुछ गुर्दे की बीमारियों की प्रगति को धीमा करने में भी मदद करती है।

साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में चक्कर आना, थकान, सिरदर्द, सूखी खांसी और जी मिचलाना शामिल हैं। ये आमतौर पर हल्के होते हैं और शरीर के अनुकूल होने पर कम हो जाते हैं। गंभीर दुष्प्रभाव दुर्लभ हैं लेकिन इनमें चेहरे, होंठ, गले या जीभ में सूजन (एंजियोएडेमा), गुर्दे की समस्या और उच्च पोटेशियम स्तर शामिल हो सकते हैं। किसी भी गंभीर लक्षण पर तुरंत डॉक्टर से संपर्क करें।

सुरक्षा सलाह: इस दवा को लेने से पहले अपने डॉक्टर को गुर्दे की बीमारी, यकृत की बीमारी, मधुमेह या एंजियोएडेमा के इतिहास के बारे में बताएं। पोटेशियम सप्लीमेंट या नमक के विकल्प का सेवन बिना डॉक्टर की सलाह के न करें। यदि आप गर्भवती हैं या गर्भवती होने की योजना बना रही हैं तो यह दवा न लें। शराब से बचें क्योंकि इससे चक्कर आ सकते हैं। बैठने या लेटने की स्थिति से धीरे-धीरे उठें। डॉक्टर की सलाह के बिना दवा बंद न करें।

💡 Did You Know? The first generic medicine was introduced in India in 1970 after the Patents Act was amended.

💊 hiril 5mg tablet Uses & Benefits

[{"condition":"Hypertension","description":"This medicine is used to lower high blood pressure, reducing the risk of stroke, heart attack, and kidney problems.","evidence":"Well-established"},{"condition":"Heart failure","description":"It helps improve symptoms and survival in patients with heart failure by reducing the workload on the heart.","evidence":"Well-established"},{"condition":"Asymptomatic left ventricular dysfunction","description":"Used to prevent the progression to symptomatic heart failure in patients with reduced ejection fraction.","evidence":"Well-established"},{"condition":"Post-myocardial infarction","description":"Administered after a heart attack to improve survival and reduce the risk of future cardiovascular events.","evidence":"Well-established"},{"condition":"Diabetic nephropathy","description":"Used to slow the progression of kidney disease in patients with diabetes and proteinuria.","evidence":"Well-established"}]

Off-label uses: [{"condition":"Scleroderma renal crisis","description":"Sometimes used off-label for managing scleroderma renal crisis, a rare but serious kidney complication.","evidence":"Limited"},{"condition":"Migraine prophylaxis","description":"Occasionally prescribed off-label to prevent migraines, though evidence is limited.","evidence":"Limited"}]

Primary treatment for: Hypertension

Also treats: Heart failure, Post-myocardial infarction, Diabetic nephropathy

📋 Drug Information

Generic Name(s)Enalapril (5mg)
Brand Namehiril 5mg tablet
ManufacturerHinglaj Laboratories
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassCARDIAC
Action ClassAngiotensin-converting enzyme (ACE) inhibitors
Route of AdministrationOral
StorageStore at room temperature between 15°C and 30°C (59°F to 86°F). Protect from moisture and light. Keep in the original container.
Shelf Life24 months from the date of manufacture.
WHO GuidelineWHO recommends ACE inhibitors like enalapril as first-line treatment for hypertension in certain patient populations, especially those with diabetes or heart failure.
ICMR GuidelineICMR guidelines recommend ACE inhibitors for the management of hypertension, particularly in patients with comorbid conditions like diabetes and heart failure.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Take this medicine at the same time each day to maintain consistent blood pressure control.
2
Monitor your blood pressure regularly and keep a log to share with your doctor.
3
Report any persistent dry cough to your doctor; a different medicine may be needed.
4
Avoid potassium supplements and salt substitutes unless approved by your doctor.
5
Stay hydrated, especially during hot weather or exercise, to prevent dizziness.
6
Do not stop this medicine abruptly without consulting your doctor, as it can cause rebound hypertension.
7
Inform your doctor if you experience swelling of the face, lips, or tongue, as this may be a sign of angioedema.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅
High blood pressure
This medicine is commonly prescribed for hypertension.
Likely Use
✅
Shortness of breath due to heart failure
This medicine helps improve symptoms of heart failure.
Likely Use
❌
Fever
This medicine is not a fever reducer.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionEnalapril is rapidly absorbed from the gastrointestinal tract after oral administration. The absorption is not significantly affected by food. However, the rate of absorption may be slightly reduced when taken with a high-fat meal.
DistributionEnalapril is widely distributed in the body, but it crosses the blood-brain barrier poorly. It crosses the placenta and is distributed into breast milk in small amounts.
Protein BindingEnalapril is approximately 50-60% bound to plasma proteins.
MetabolismEnalapril is a prodrug that is hydrolyzed in the liver to its active metabolite, enalaprilat. This conversion is rapid and extensive.
Half-LifeThe elimination half-life of enalaprilat is approximately 11 hours. In patients with renal impairment, the half-life is prolonged.
ExcretionEnalapril and its metabolites are primarily excreted by the kidneys. About 60-80% of an oral dose is recovered in urine, with the remainder in feces.
BioavailabilityThe oral bioavailability of enalapril is approximately 60%. The bioavailability of the active metabolite, enalaprilat, after oral administration of enalapril is about 40%.
Onset of ActionThe onset of blood pressure-lowering effect is usually within 1 hour after oral administration, with peak effect occurring in 4-6 hours.
Peak Plasma TimePeak plasma concentration of enalaprilat is reached approximately 3-4 hours after oral administration of enalapril.
Duration of ActionThe duration of action is approximately 24 hours, allowing for once-daily dosing in most patients.

How It Works

This medicine works by inhibiting the angiotensin-converting enzyme (ACE). ACE is responsible for converting angiotensin I to angiotensin II, a potent vasoconstrictor. By blocking this conversion, this medicine reduces levels of angiotensin II, leading to relaxation of blood vessels (vasodilation) and decreased secretion of aldosterone. This results in lower blood pressure, reduced sodium and water retention, and decreased workload on the heart. Additionally, it increases levels of bradykinin, a vasodilator, which contributes to its blood pressure-lowering effect but may also cause side effects like cough.

Mechanism Steps

1
Inhibition of ACE: This medicine binds to and inhibits the angiotensin-converting enzyme, preventing the conversion of angiotensin I to angiotensin II.
2
Reduction in angiotensin II: Lower levels of angiotensin II lead to less vasoconstriction and reduced aldosterone release.
3
Vasodilation: Blood vessels relax and widen, lowering blood pressure and reducing the heart's workload.
4
Decreased aldosterone secretion: Reduced aldosterone leads to less sodium and water retention, further lowering blood pressure.
5
Increased bradykinin: ACE inhibition also increases bradykinin levels, contributing to vasodilation but potentially causing cough.

💡 How to Take hiril 5mg tablet

Strength: Enalapril 5 mg immediate-release tablet

1Take this medicine exactly as prescribed by your doctor.
2Swallow the tablet whole with a glass of water.
3You may take it with or without food.
4Take it at the same time each day to maintain consistent levels.
5Do not crush, chew, or break the tablet unless instructed.
6If you miss a dose, follow the missed dose instructions.

Dosage Information

Adult DosageThe usual starting dose for hypertension is 5 mg once daily, but it may be increased to 10-40 mg daily in one or two divided doses. For heart failure, the starting dose is 2.5 mg twice daily, gradually increased to a target of 10-20 mg twice daily. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageElderly patients may have reduced renal function and may require lower initial doses. Start with 2.5 mg once daily and titrate slowly. Monitor renal function and potassium levels.
Renal ImpairmentIn patients with renal impairment, the dose should be reduced. For creatinine clearance 30-80 mL/min, start with 5 mg once daily; for 10-30 mL/min, start with 2.5 mg once daily; for <10 mL/min, start with 2.5 mg on dialysis days. Dose must be individualized by a qualified clinician.
Hepatic ImpairmentIn patients with hepatic impairment, the dose may need to be reduced. Monitor liver function. Dose must be individualized by a qualified clinician.
Maximum Daily DoseThe maximum recommended daily dose is 40 mg for hypertension and 40 mg for heart failure, but individualization is required.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With or without food
Take consistently
Food does not significantly affect absorption.
High-potassium foods
Moderate intake
May increase potassium levels.
Salt substitutes
Avoid
Often contain potassium.

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of hiril 5mg tablet

✅ Common Side Effects

Dizziness (Common (5-10%))
Usually resolves as your body adjusts. Rise slowly from sitting or lying positions. Consult your doctor if persistent.
Fatigue (Common (5-10%))
Get adequate rest. If fatigue interferes with daily activities, consult your doctor.
Dry cough (Common (5-20%))
This may be due to the medicine. Consult your doctor; a different class of medicine may be needed.
Headache (Common (5-10%))
Usually resolves on its own. Consult your doctor if severe or persistent.
Nausea (Common (1-5%))
Take with food to reduce nausea. Consult your doctor if it continues.

🚨 Serious Side Effects

Angioedema (Rare (<0.1%))
Seek immediate medical attention if you experience swelling of the face, lips, tongue, or throat, or difficulty breathing.
Severe allergic reaction (Rare (<0.1%))
Call emergency services if you have rash, itching, severe dizziness, or trouble breathing.
Kidney impairment (Uncommon (0.1-1%))
Regular monitoring of kidney function is required. Report decreased urine output or swelling.
Hyperkalemia (high potassium) (Uncommon (0.1-1%))
Avoid potassium supplements. Report muscle weakness or irregular heartbeat.
Severe hypotension (Uncommon (0.1-1%))
Report fainting or severe dizziness. Dose adjustment may be needed.

⚠️ Rare Side Effects

Neutropenia
Report fever, sore throat, or unusual tiredness. Blood tests may be needed.
Hepatitis
Report yellowing of skin or eyes, dark urine, or abdominal pain.
Pancreatitis
Seek immediate care for severe abdominal pain.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Potassium supplements Major
Spironolactone Major
Ibuprofen Major
Lithium Major
Furosemide Moderate
Metoprolol Moderate
Amitriptyline Moderate
Antacids Minor
Cimetidine Minor

🚨 Major Interactions

  • Potassium supplements
  • Potassium-sparing diuretics (e.g., spironolactone)
  • NSAIDs (e.g., ibuprofen)
  • Lithium

⚡ Moderate Interactions

  • Diuretics
  • Beta-blockers
  • Tricyclic antidepressants

🍷 Alcohol Interaction

Alcohol may enhance the blood pressure-lowering effect of this medicine, leading to dizziness, lightheadedness, and fainting. It is advisable to limit or avoid alcohol while taking this medicine.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["History of angioedema related to ACE inhibitors","Hereditary or idiopathic angioedema","Pregnancy","Bilateral renal artery stenosis","Concomitant use with aliskiren in patients with diabetes"]

⚠️ Warnings & Precautions

["Angioedema: May occur at any time. Discontinue and seek emergency care if suspected.","Hypotension: May occur, especially in volume-depleted patients. Monitor blood pressure.","Hyperkalemia: Risk increased with potassium supplements, potassium-sparing diuretics, or renal impairment.","Renal impairment: Dose adjustment may be needed. Monitor kidney function.","Cough: Persistent dry cough may occur; consider alternative if bothersome.","Neutropenia/Agranulocytosis: Rare, but monitor blood counts in high-risk patients.","Use in children: Safety and efficacy not established for children under 6 years."]

🤱 Lactation Safety

Enalapril is present in breast milk in small amounts. It is generally considered safe during breastfeeding, but consult your doctor to weigh the benefits and risks.

💊 Overdose Management

Overdose may cause severe hypotension, bradycardia, and electrolyte imbalances. Treatment is supportive and symptomatic. If overdose is suspected, contact a poison control center or emergency room immediately. Measures may include intravenous fluids, vasopressors, and monitoring of vital signs and electrolytes.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up.

Additional Safety Advice

General Safety

Before taking this medicine, inform your doctor if you have kidney disease, liver disease, diabetes, or a history of angioedema. Avoid using potassium supplements or salt substitutes containing potassium without consulting your doctor, as this medicine can increase potassium levels. Do not take this medicine if you are pregnant or planning to become pregnant, as it can harm the unborn baby. Use effective contraception while taking this medicine. Avoid alcohol, as it can enhance the blood pressure-lowering effect and cause dizziness. Stand up slowly from a sitting or lying position to prevent dizziness. Do not stop taking this medicine abruptly without consulting your doctor, as this can cause a rebound increase in blood pressure. Keep all appointments for monitoring blood pressure, kidney function, and potassium levels.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients may be more sensitive to the blood pressure-lowering effects and may require lower initial doses. Monitor renal function and potassium levels closely. Risk of falls due to dizziness may be increased.

🤰 Pregnancy Planning (TTC)

This medicine is contraindicated during pregnancy. If you are planning to become pregnant, consult your doctor to switch to a safer alternative before conception. Use effective contraception while taking this medicine.

🏥 Post-Surgery Considerations

Inform your surgeon and anesthesiologist that you are taking this medicine. It may need to be temporarily stopped before surgery to prevent hypotension during anesthesia. Follow your doctor's instructions.

🦷 Dental Procedures

Inform your dentist that you are taking this medicine. It may cause dry mouth or dizziness during dental procedures. Maintain good oral hygiene and stay hydrated.

💚 Lifestyle Tips for Better Results

🏃
Maintain a healthy weight to help control blood pressure.
🥗
Engage in regular physical activity like walking or swimming.
😴
Reduce salt intake to enhance blood pressure control.
💧
Limit alcohol consumption to avoid dizziness and low blood pressure.
🧘
Quit smoking to reduce cardiovascular risk.
🌞
Manage stress through relaxation techniques like yoga or meditation.

🏋️ Exercise Considerations

Exercise is generally safe while taking this medicine, but avoid sudden strenuous activities that may cause dizziness. Stay hydrated and rise slowly after exercise. If you experience dizziness or fainting during exercise, stop and consult your doctor.

🥗 Diet Recommendations

Follow a low-sodium diet (DASH diet).
Include potassium-rich foods in moderation if kidney function is normal.
Avoid salt substitutes containing potassium.
Limit processed foods high in sodium.
Stay well hydrated.

💼 Impact on Daily Work & Life

This medicine may cause dizziness, especially when starting treatment or increasing the dose. Avoid driving or operating heavy machinery until you know how it affects you. Most people can continue their normal activities once adjusted to the medication.

🛑 When to Stop This Medicine

Do not stop this medicine without consulting your doctor. If you experience serious side effects like angioedema, severe hypotension, or kidney problems, seek immediate medical attention. Your doctor may adjust the dose or switch to a different medicine.

📅 Long-Term Use Effects

Long-term use of this medicine is generally safe and effective for managing hypertension and heart failure. Regular monitoring of blood pressure, kidney function, and potassium levels is required. Some patients may develop a persistent dry cough. Rarely, it can cause kidney impairment or high potassium. Do not stop the medicine without consulting your doctor.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Lifestyle modifications

Diet, exercise, and weight loss can help control blood pressure and complement medicine.

Evidence: Well-established
Angiotensin receptor blockers (ARBs)

Alternative class for patients who cannot tolerate ACE inhibitors due to cough.

Evidence: Well-established

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

No specific vaccine interactions are known. However, consult your doctor before receiving any live vaccines while on this medicine.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

Carry this medicine in its original packaging with a copy of your prescription. Keep it in your carry-on luggage to avoid loss. Store at room temperature and protect from moisture. If traveling across time zones, consult your doctor about adjusting dosing times. Check local customs regulations for carrying prescription medicines.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 55-year-old man with newly diagnosed hypertension
He was prescribed this medicine 5 mg once daily. After two weeks, his blood pressure improved from 160/100 to 130/85. He experienced a mild dry cough but it was manageable. He emphasized taking the medicine at the same time every morning and monitoring his blood pressure at home.
💡 Lesson: Consistent daily dosing and regular monitoring lead to better blood pressure control.
👤 A 62-year-old woman with heart failure
She started this medicine at 2.5 mg twice daily and gradually increased to 10 mg twice daily. She noticed improved energy levels and less shortness of breath within a month. She had to avoid potassium-rich foods and salt substitutes as advised by her doctor.
💡 Lesson: Gradual dose titration and dietary precautions are key to safe and effective treatment.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: This medicine starts lowering blood pressure within 1 hour, with peak effect in 4-6 hours. Full benefits may take several weeks.

Q: Can I take this medicine with food?

A: Yes, you can take it with or without food. Taking it with food may reduce stomach upset.

Q: What should I do if I miss a dose?

A: Take it as soon as you remember. If it's almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double dose.

Q: Is it safe during pregnancy?

A: No, this medicine is contraindicated in pregnancy as it can harm the fetus. Consult your doctor immediately if you become pregnant.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my kidney function?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?

🔄 Substitutes for hiril 5mg tablet

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: Enalapril can be stopped once blood pressure is normal.
    Fact: Enalapril controls but does not cure hypertension. It should be continued as prescribed to maintain blood pressure control.
  • Myth: Enalapril is safe to use during pregnancy.
    Fact: Enalapril is contraindicated in pregnancy as it can harm the fetus.
  • Myth: Enalapril causes cough in everyone.
    Fact: Only about 5-20% of patients experience a dry cough; many do not.

🔄 Alternative Options

Generic Alternatives

  • Enalapril maleate 5 mg tablet

Brand Alternatives

  • Envas 5 mg tablet
  • Enalapril 5 mg tablet (various brands)

📊 Comparison with Similar Medicines

[{"medicine":"Enalapril","class":"ACE inhibitor","half_life":"11 hours","common_side_effects":"Cough, dizziness, fatigue"},{"medicine":"Lisinopril","class":"ACE inhibitor","half_life":"12 hours","common_side_effects":"Cough, dizziness, headache"},{"medicine":"Losartan","class":"ARB","half_life":"6-9 hours","common_side_effects":"Dizziness, fatigue, less cough"}]

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