hhderm cream - Clotrimazole (1% w/w) + Fusidic Acid (2% w/w) medicine

Emcort CF Cream: A Comprehensive Guide to Uses, Side Effects, and Safety

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🏭 Hegde and Hegde Pharmaceutical LLP 📦 Varies by brand 💊 Allopathy 📅 Updated: Oct 23, 2026
📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Well-established for approved indications.
Reviewed by
SaathiMed Expert Panel | Oct 23, 2026
🩺
Medically Fact-Checked & Clinically Verified by SaathiMed Clinical Review Board
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026

When to Call Your Doctor IMMEDIATELY

  • Severe allergic reaction with swelling of face, lips, or throat.
  • Difficulty breathing or swallowing.
  • Severe skin blistering or peeling.
  • Signs of secondary infection such as increased pain, redness, or pus.
  • No improvement after 7 days of use.
  • Fever or chills accompanying the skin infection.

If experiencing severe symptoms, call emergency services immediately.

What is hhderm cream used for?

This medicine is a topical cream combining clotrimazole (antifungal) and fusidic acid (antibiotic) to treat mixed skin infections. Apply a thin layer to the affected area 2-3 times daily as prescribed.

  • Generic Name: Clotrimazole (1% w/w) + Fusidic Acid (2% w/w)
  • Manufacturer: Hegde and Hegde Pharmaceutical LLP
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 hhderm cream के बारे में (Hindi Summary)

उपयोग: यह दवा एक टॉपिकल क्रीम है जिसमें क्लोट्रिमाज़ोल (एंटीफंगल) और फ्यूसिडिक एसिड (एंटीबायोटिक) शामिल हैं। यह त्वचा के उन संक्रमणों के इलाज के लिए उपयोग की जाती है जो फंगस और बैक्टीरिया दोनों के कारण होते हैं, जैसे कि संक्रमित एक्जिमा, एथलीट फुट, और अन्य मिश्रित त्वचा संक्रमण। यह क्रीम प्रभावित क्षेत्र पर पतली परत में लगाई जाती है, आमतौर पर दिन में 2-3 बार, डॉक्टर के निर्देशानुसार।

साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में लगाने की जगह पर हल्की जलन, खुजली, लालिमा या सूखापन शामिल हो सकते हैं। ये आमतौर पर हल्के होते हैं और उपचार जारी रखने पर ठीक हो जाते हैं। गंभीर दुष्प्रभाव दुर्लभ हैं, लेकिन यदि आपको गंभीर एलर्जी प्रतिक्रिया जैसे चकत्ते, सूजन, या सांस लेने में कठिनाई हो, तो तुरंत डॉक्टर से संपर्क करें।

सुरक्षा सलाह: यह दवा केवल बाहरी उपयोग के लिए है। आंखों, नाक, मुंह और अन्य श्लेष्मा झिल्लियों के संपर्क से बचें। यदि गलती से संपर्क हो जाए, तो पानी से अच्छी तरह धो लें। बिना डॉक्टर की सलाह के लंबे समय तक या शरीर के बड़े हिस्से पर इसका उपयोग न करें। गर्भावस्था या स्तनपान के दौरान डॉक्टर से परामर्श करें। बच्चों की पहुंच से दूर रखें। यदि लक्षण बने रहें या बिगड़ जाएं, तो डॉक्टर से मिलें।

💡 Did You Know? The first generic medicine was introduced in India in 1970 after the Patents Act was amended.

💊 hhderm cream Uses & Benefits

[{"condition":"Infected eczema","description":"Treats fungal and bacterial infections that complicate eczema lesions.","evidence":"Well-established"},{"condition":"Infected dermatitis","description":"Used when dermatitis becomes secondarily infected with fungi and bacteria.","evidence":"Well-established"},{"condition":"Athlete's foot with bacterial infection","description":"Combats both fungal and bacterial components of the infection.","evidence":"Well-established"},{"condition":"Fungal skin infections with suspected bacterial co-infection","description":"Provides broad coverage for mixed infections.","evidence":"Well-established"}]

Off-label uses: [{"condition":"Prevention of infection in minor skin injuries","description":"Sometimes used off-label to prevent infection in cuts and abrasions.","evidence":"Limited"}]

Primary treatment for: Mixed fungal and bacterial skin infections

Also treats: Infected eczema, Infected dermatitis, Athlete's foot with bacterial infection

📋 Drug Information

Generic Name(s)Clotrimazole (1% w/w) + Fusidic Acid (2% w/w)
Brand Namehhderm cream
ManufacturerHegde and Hegde Pharmaceutical LLP
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassDERMA
Action Class
Route of AdministrationTopical
StorageStore below 25°C, protected from light and moisture. Do not freeze. Keep the tube tightly closed when not in use.
Shelf Life24 months from the date of manufacture.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Apply the cream exactly as prescribed, usually two to three times daily.
2
Clean and dry the affected area before application to enhance absorption.
3
Avoid using this cream on the face unless specifically directed by a doctor.
4
Complete the full course of treatment even if symptoms improve early.
5
If no improvement is seen after 7 days, consult your doctor for reassessment.
6
Do not share this cream with others, as it may not be suitable for their condition.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅
Itchy, red skin with scaling
This medicine is commonly prescribed for fungal skin infections.
Likely Use
✅
Skin infection with pus and redness
This medicine is used for bacterial skin infections.
Likely Use
❌
Fever
This medicine is not a primary fever reducer.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionNot established from the available information.
DistributionNot established from the available information.
Protein BindingNot established from the available information.
MetabolismNot established from the available information.
Half-LifeNot established from the available information.
ExcretionNot established from the available information.
BioavailabilityNot established from the available information.
Onset of ActionNot established from the available information.
Peak Plasma TimeNot established from the available information.
Duration of ActionNot established from the available information.

How It Works

This medicine combines two active ingredients with distinct mechanisms. Clotrimazole, an imidazole antifungal, inhibits the synthesis of ergosterol, a vital component of fungal cell membranes, by blocking the enzyme lanosterol 14α-demethylase. This leads to increased membrane permeability and leakage of cellular contents, resulting in fungal cell death. Fusidic acid, a steroid antibiotic, inhibits bacterial protein synthesis by preventing the translocation of elongation factor G (EF-G) from the ribosome, thereby stopping bacterial growth. Together, they provide antifungal and antibacterial action.

Mechanism Steps

1
Clotrimazole inhibits ergosterol synthesis: Clotrimazole binds to and inhibits lanosterol 14α-demethylase, blocking the conversion of lanosterol to ergosterol, a key component of fungal cell membranes.
2
Fungal cell membrane damage: The lack of ergosterol and accumulation of toxic sterols increase membrane permeability, causing leakage of intracellular contents and fungal cell death.
3
Fusidic acid inhibits bacterial protein synthesis: Fusidic acid binds to elongation factor G (EF-G) and prevents its release from the ribosome, thereby inhibiting the translocation step of protein synthesis.
4
Bacterial growth arrest: Without protein synthesis, bacteria cannot grow or multiply, leading to their eventual death or inhibition.

💡 How to Take hhderm cream

Strength: Cream containing clotrimazole 1% w/w and fusidic acid 2% w/w.

1Wash your hands thoroughly before and after applying the cream, unless treating the hands.
2Clean and dry the affected area gently.
3Apply a thin layer of the cream to the affected area and surrounding skin.
4Rub it in gently until it is absorbed.
5Do not cover the area with a bandage unless instructed by your doctor.
6Avoid contact with eyes, nose, mouth, and other mucous membranes.
7Use as prescribed, typically 2-3 times daily.

Dosage Information

Adult DosageApply a thin layer of this medicine to the affected area and surrounding skin two to three times daily, or as directed by your doctor. The duration of treatment depends on the type and severity of the infection. For fungal infections, treatment may continue for 2-4 weeks. For bacterial infections, duration is typically 1-2 weeks. Dose must be individualized by a qualified clinician based on indication, age, and clinical response.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageNo specific dosage adjustments are required for elderly patients. However, they may be more susceptible to skin irritation. Use with caution and consult a doctor if any adverse effects occur.
Renal ImpairmentNo dosage adjustment is required as systemic absorption is minimal.
Hepatic ImpairmentNo dosage adjustment is required as systemic absorption is minimal.
Maximum Daily DoseNot established from the available information. Use only as prescribed by a doctor.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

No food interactions
Not applicable
This is a topical cream, so food does not affect its use.

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Apply the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not apply a double dose to catch up.

⚠️ Side Effects of hhderm cream

✅ Common Side Effects

Application site burning (Common (1-10%))
Usually resolves on its own. If persistent or severe, consult your doctor.
Application site itching (Common (1-10%))
Avoid scratching. If itching is severe, consult your doctor.
Application site redness (Common (1-10%))
May be a sign of irritation. If it worsens, stop use and consult your doctor.
Application site dryness (Common (1-10%))
Use a moisturizer if needed. Consult your doctor if dryness persists.

🚨 Serious Side Effects

Severe allergic reaction (anaphylaxis) (Rare (<0.1%))
Seek immediate medical attention if you experience rash, swelling, difficulty breathing, or dizziness.
Severe skin irritation or contact dermatitis (Rare (<0.1%))
Discontinue use and consult a doctor if you develop severe redness, blistering, or peeling.

⚠️ Rare Side Effects

Secondary infection
Consult your doctor if you notice new signs of infection such as increased redness, swelling, or pus.

Consult your doctor if you experience any unusual symptoms.

🛡️ Safety & Warnings

🚫 Contraindications

["Hypersensitivity to clotrimazole, fusidic acid, or any component of the cream","Do not use in the eyes or on mucous membranes","Do not use on open wounds or large areas of broken skin without medical advice"]

⚠️ Warnings & Precautions

["For external use only.","Avoid contact with eyes, nose, mouth, and other mucous membranes.","Do not use for prolonged periods without medical supervision.","If irritation or sensitization occurs, discontinue use and consult a doctor.","Do not use on children under 2 years of age unless directed by a doctor.","Keep out of reach of children.","Do not use if the tube seal is broken.","Inform your doctor if you are pregnant, planning pregnancy, or breastfeeding."]

🤱 Lactation Safety

It is not known whether clotrimazole or fusidic acid pass into breast milk when applied topically. However, systemic absorption is minimal. Consult your doctor before use if breastfeeding. Avoid applying to the breast area to prevent infant exposure.

💊 Overdose Management

Overdose with topical application is unlikely. If accidental ingestion occurs, seek medical attention immediately. Symptoms of ingestion may include nausea, vomiting, and abdominal pain. Treatment is symptomatic and supportive.

⏰ Missed Dose

If you miss a dose, apply it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not apply a double dose to make up for a missed one.

Additional Safety Advice

General Safety

For external use only. Avoid contact with eyes, nose, mouth, and other mucous membranes. If accidental contact occurs, rinse thoroughly with water. Do not apply to large areas of the body or use for prolonged periods without medical advice. Wash your hands before and after applying the cream, unless the hands are the treated area. Do not cover the treated area with airtight dressings unless instructed by your doctor. Inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding. Do not use this medicine if you are allergic to any of its components. Keep out of reach of children. If symptoms persist or worsen after a few days of use, consult your doctor.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients may have thinner skin and are more prone to irritation. Use with caution and monitor for any adverse reactions.

🤰 Pregnancy Planning (TTC)

Consult your doctor before using this medicine if you are pregnant, planning to become pregnant, or breastfeeding. The safety of this combination in pregnancy has not been fully established.

🏥 Post-Surgery Considerations

Consult your surgeon before using this cream on surgical wounds, as it may interfere with healing or mask signs of infection.

🦷 Dental Procedures

No specific considerations for dental procedures, as this is a topical skin cream.

💚 Lifestyle Tips for Better Results

🏃
Keep the affected area clean and dry.
🥗
Avoid sharing towels, clothing, or footwear to prevent spread of infection.
😴
Wear loose-fitting, breathable clothing to reduce irritation.
💧
Maintain good hygiene practices.
🧘
Avoid scratching the affected area to prevent worsening of infection.

🏋️ Exercise Considerations

No specific exercise restrictions are required while using this medicine. However, if the infection is on the feet, avoid activities that cause excessive sweating or friction until healed.

🥗 Diet Recommendations

Eat a balanced diet rich in vitamins and minerals to support skin health.
Stay hydrated by drinking plenty of water.
Include probiotic-rich foods like yogurt to support overall immunity.

💼 Impact on Daily Work & Life

This medicine is applied topically and is unlikely to affect your ability to drive or operate machinery. However, if you experience any allergic reaction, avoid these activities until you feel better.

🛑 When to Stop This Medicine

Stop using this medicine and consult your doctor if your symptoms worsen, if you experience severe side effects, or if there is no improvement after the prescribed duration. Do not stop abruptly without consulting your doctor if you are on a long-term treatment plan.

📅 Long-Term Use Effects

Prolonged use of this medicine may lead to skin thinning, secondary infections, or development of resistance. It should only be used for the duration prescribed by your doctor. Regular monitoring by a healthcare professional is advised if long-term use is necessary.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Topical antifungal alone

If only fungal infection is present, a single-agent antifungal cream may be sufficient.

Evidence: Well-established
Topical antibiotic alone

If only bacterial infection is present, a single-agent antibiotic cream may be used.

Evidence: Well-established
Oral medications

For severe or widespread infections, oral antifungals or antibiotics may be prescribed.

Evidence: Well-established

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

No known interactions with vaccines. However, consult your doctor before vaccination if you have an active skin infection.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

When traveling, carry this medicine in its original packaging with the prescription label intact. Bring a copy of your prescription to avoid issues at customs. Store it in a cool, dry place away from direct sunlight. If traveling to a hot climate, keep it in a cool bag. No time zone adjustments are needed for topical application. Ensure you have enough supply for your trip.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 35-year-old woman with infected eczema on her hands.
She was prescribed this cream for a mixed fungal and bacterial infection. After using it twice daily for two weeks, her skin cleared significantly. She noted that applying it after washing and drying her hands helped with absorption.
💡 Lesson: Consistent application and proper skin hygiene enhance the effectiveness of the treatment.
👤 A 50-year-old man with athlete's foot and secondary bacterial infection.
He used this cream as directed for three weeks. The itching and redness reduced within the first week, and the infection resolved completely by the end of the course. He emphasized not skipping doses.
💡 Lesson: Completing the full course prevents recurrence and ensures both fungal and bacterial components are eradicated.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: You may start to see improvement within a few days, but complete healing may take 1-4 weeks depending on the infection.

Q: Can I use this cream on my face?

A: It is not recommended for use on the face unless specifically directed by a doctor, as facial skin is more sensitive.

Q: Is it safe for children?

A: Consult a pediatrician before using this cream on children, especially those under 2 years old.

Q: What if I miss a dose?

A: Apply it as soon as you remember, but if it's almost time for the next dose, skip the missed dose and continue with your regular schedule.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I use this cream on my face?
  • How long does it take to work?
  • Is it safe for children?
  • Can I use it during pregnancy?
  • What if I miss a dose?
  • Are there any food restrictions?

🔄 Substitutes for hhderm cream

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: This cream can cure any skin infection.
    Fact: It is effective only against fungal and bacterial infections. It does not treat viral infections like herpes or warts.
  • Myth: Using more cream will make it work faster.
    Fact: Using more than prescribed does not speed up healing and may increase side effects.
  • Myth: It is safe to use indefinitely.
    Fact: Prolonged use can lead to skin thinning, secondary infections, or resistance. Use only as directed.

🔄 Alternative Options

Generic Alternatives

  • Clotrimazole 1% + Fusidic acid 2% cream

Brand Alternatives

  • Emcort CF Cream

📊 Comparison with Similar Medicines

[{"medicine":"This medicine","composition":"Clotrimazole 1% + Fusidic acid 2%","uses":"Mixed fungal and bacterial skin infections","route":"Topical"},{"medicine":"Clotrimazole 1% cream","composition":"Clotrimazole 1%","uses":"Fungal skin infections only","route":"Topical"},{"medicine":"Fusidic acid 2% cream","composition":"Fusidic acid 2%","uses":"Bacterial skin infections only","route":"Topical"}]

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