glenmark clotrimazole 1 vaginal tablet - Clotrimazole (500mg) medicine

Clotrimazole 500mg Vaginal Tablet: Complete Guide

No reviews yet
🏭 Glenmark Pharmaceuticals Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Sep 25, 2026
📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Well-established for vulvovaginal candidiasis.
Reviewed by
SaathiMed Expert Panel | Sep 25, 2026
🩺
Medically Fact-Checked & Clinically Verified by SaathiMed Clinical Review Board
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026

When to Call Your Doctor IMMEDIATELY

  • Severe allergic reaction (rash, swelling, difficulty breathing)
  • Severe vaginal pain or bleeding
  • Fever with chills
  • Foul-smelling discharge
  • No improvement after 7 days of treatment
  • New symptoms such as pelvic pain

If experiencing severe symptoms, call emergency services immediately.

What is glenmark clotrimazole 1 vaginal tablet used for?

This medicine is a vaginal tablet containing clotrimazole 500mg, used to treat vaginal yeast infections. It works by damaging the fungal cell membrane, leading to fungal cell death. It is inserted into the vagina as a single dose, usually at bedtime.

  • Generic Name: Clotrimazole (500mg)
  • Manufacturer: Glenmark Pharmaceuticals Ltd
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 glenmark clotrimazole 1 vaginal tablet के बारे में (Hindi Summary)

उपयोग: यह दवा योनि में होने वाले फंगल संक्रमण (यीस्ट इन्फेक्शन) के इलाज के लिए इस्तेमाल की जाती है। इसमें क्लोट्रिमाजोल 500mg होता है, जो फंगस को मारता है। यह योनि में डालने वाली टैबलेट है, इसे मुंह से नहीं लेना चाहिए।

साइड इफेक्ट्स: आम दुष्प्रभावों में योनि में जलन, खुजली या असुविधा शामिल हैं। ये आमतौर पर हल्के होते हैं और अपने आप ठीक हो जाते हैं। गंभीर एलर्जी प्रतिक्रिया दुर्लभ है, लेकिन अगर सांस लेने में कठिनाई, चेहरे या गले में सूजन हो तो तुरंत डॉक्टर से मिलें।

सुरक्षा सलाह: इस दवा का इस्तेमाल डॉक्टर के निर्देशानुसार ही करें। टैबलेट को योनि में गहराई तक डालें, रात को सोने से पहले। उपयोग से पहले और बाद में हाथ धोएं। इलाज के दौरान संभोग से बचें। टैम्पोन या डूश का इस्तेमाल न करें। गर्भवती या स्तनपान कराने वाली महिलाएं डॉक्टर से सलाह लें।

💡 Did You Know? India is the largest provider of generic medicines globally, supplying over 50% of global vaccine demand.

💊 glenmark clotrimazole 1 vaginal tablet Uses & Benefits

  • [{"condition":"Vulvovaginal candidiasis (vaginal yeast infection)","description":"Treats vaginal yeast infections caused by Candida albicans and other Candida species.
  • Relieves symptoms such as itching, burning, and abnormal discharge.","evidence":"Well-established"}]

Off-label uses: []

Primary treatment for: Vulvovaginal candidiasis

📋 Drug Information

Generic Name(s)Clotrimazole (500mg)
Brand Nameglenmark clotrimazole 1 vaginal tablet
ManufacturerGlenmark Pharmaceuticals Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassDERMA
Action ClassFungal ergosterol synthesis inhibitor
Route of AdministrationVaginal
StorageStore at room temperature (15-30°C). Protect from light and moisture.
Shelf Life24 months from the date of manufacture.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Insert the tablet at bedtime to allow it to dissolve overnight.
2
Wash your hands before and after using the applicator.
3
Avoid sexual intercourse during treatment to prevent irritation and reinfection.
4
Wear loose-fitting cotton underwear to allow air circulation.
5
Complete the full course even if symptoms improve early.
6
If symptoms persist beyond 7 days, consult your doctor.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅
Vaginal itching
This medicine is commonly prescribed for this.
Likely Use
✅
Vaginal discharge
This medicine treats abnormal discharge caused by yeast.
Likely Use
❌
Fever
This medicine is not a fever reducer.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionMinimal systemic absorption after vaginal administration. Plasma levels are very low and often undetectable.
DistributionNot established from the available information.
Protein BindingNot established from the available information.
MetabolismNot established from the available information.
Half-LifeNot established from the available information.
ExcretionNot established from the available information.
BioavailabilityLow systemic bioavailability after vaginal administration.
Onset of ActionSymptom relief may begin within 1-2 days, but complete resolution may take up to 7 days.
Peak Plasma TimeNot established from the available information.
Duration of ActionThe antifungal effect lasts for several days after application.

How It Works

Clotrimazole works by inhibiting the synthesis of ergosterol, a key component of the fungal cell membrane. This leads to increased permeability of the cell membrane and leakage of cellular contents, ultimately causing fungal cell death.

Mechanism Steps

1
Binding to fungal enzyme: Clotrimazole binds to lanosterol 14α-demethylase, a cytochrome P450 enzyme in fungi.
2
Inhibition of ergosterol synthesis: This binding inhibits the conversion of lanosterol to ergosterol, a vital component of the fungal cell membrane.
3
Membrane damage: Without ergosterol, the fungal cell membrane becomes permeable, leading to leakage of essential cellular components.
4
Fungal cell death: The loss of membrane integrity results in fungal cell death, resolving the infection.

💡 How to Take glenmark clotrimazole 1 vaginal tablet

Strength: Vaginal tablet, 500mg

1Wash your hands thoroughly before and after inserting the tablet.
2Lie on your back with your knees bent and feet flat on the floor.
3Insert the tablet high into the vagina using the applicator provided.
4Push the plunger to release the tablet.
5Withdraw the applicator and wash it with warm soapy water.
6Wash your hands again.

Dosage Information

Adult DosageThe usual adult dose is one 500mg vaginal tablet inserted high into the vagina at bedtime as a single dose. In some cases, your doctor may prescribe a different regimen. Dose must be individualized by a qualified clinician based on the severity of infection and patient factors.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageNo specific dose adjustments are required for elderly patients. Use as directed by a doctor.
Renal ImpairmentNo dose adjustment is required for patients with renal impairment.
Hepatic ImpairmentNo dose adjustment is required for patients with hepatic impairment.
Maximum Daily Dose500mg as a single dose. Do not exceed the prescribed dose.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of glenmark clotrimazole 1 vaginal tablet

✅ Common Side Effects

Vaginal burning or irritation (Common (1-10%))
Usually resolves on its own. If persistent or severe, consult your doctor.
Vaginal itching (Common (1-10%))
May be due to the infection or the medicine. Consult if it worsens.
Vaginal discharge (Common (1-10%))
Usually temporary. Maintain hygiene and consult if abnormal.

🚨 Serious Side Effects

Severe allergic reaction (anaphylaxis) (Rare (<0.1%))
Seek immediate medical attention if you experience rash, swelling of face/lips/throat, or difficulty breathing.
Severe skin reaction (Rare (<0.1%))
Discontinue use and consult a doctor if you develop blistering or peeling skin.

⚠️ Rare Side Effects

Abdominal pain
Consult your doctor if pain is severe or persistent.
Headache
Usually resolves. Consult if severe.

Consult your doctor if you experience any unusual symptoms.

🛡️ Safety & Warnings

🚫 Contraindications

["Hypersensitivity to clotrimazole or any other azole antifungal","First trimester of pregnancy (unless prescribed by a doctor)"]

⚠️ Warnings & Precautions

["For vaginal use only. Do not take by mouth.","Consult a doctor if symptoms persist beyond 7 days.","Avoid sexual intercourse during treatment.","Do not use tampons or douches during treatment.","Keep out of reach of children."]

🤱 Lactation Safety

Clotrimazole is unlikely to be excreted in breast milk in significant amounts. Consult your doctor before use.

💊 Overdose Management

Overdose is unlikely due to the vaginal route. If accidental ingestion occurs, seek medical attention immediately.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose.

Additional Safety Advice

General Safety

Use this medicine only as prescribed by your doctor. Insert the tablet into the vagina using the applicator provided, preferably at bedtime. Wash your hands before and after use. Avoid sexual intercourse while using this medicine, as it may reduce effectiveness and cause irritation. Do not use tampons or douches during treatment. If you are pregnant or breastfeeding, consult your doctor before use. Keep out of reach of children. Do not use if the tablet is discolored or damaged. Complete the full course even if symptoms improve.

👴 Special Considerations for Elderly

💡 For Patients Above 65

No specific dose adjustments are required for elderly patients. Use as directed by a doctor.

🤰 Pregnancy Planning (TTC)

If you are planning pregnancy, consult your doctor before using this medicine. Clotrimazole is generally considered safe, but medical advice is recommended.

🏥 Post-Surgery Considerations

Consult your doctor before using this medicine after surgery, especially gynecological procedures.

🦷 Dental Procedures

No specific considerations for dental procedures.

💚 Lifestyle Tips for Better Results

🏃
Wear loose-fitting cotton underwear.
🥗
Avoid douching and scented feminine products.
😴
Keep the vaginal area clean and dry.
💧
Avoid tight clothing and synthetic fabrics.
🧘
Maintain a healthy diet and manage stress.

🏋️ Exercise Considerations

No specific exercise restrictions. However, avoid strenuous activities if you experience discomfort.

🥗 Diet Recommendations

Include probiotics like yogurt to support vaginal health.
Reduce sugar intake as yeast thrives on sugar.
Stay well hydrated.
Eat a balanced diet rich in fruits and vegetables.

💼 Impact on Daily Work & Life

This medicine is unlikely to affect your ability to drive or operate machinery. You can continue your daily activities as usual.

🛑 When to Stop This Medicine

Stop using this medicine if you experience a severe allergic reaction. Otherwise, complete the full course as prescribed. Consult your doctor before stopping if symptoms persist.

📅 Long-Term Use Effects

Long-term use of this medicine is not recommended without medical supervision. Prolonged use may lead to fungal resistance. If symptoms persist or recur, consult your doctor for further evaluation.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Oral antifungal medication

Fluconazole is an oral alternative for vaginal yeast infections.

Evidence: Well-established
Probiotics

May help prevent recurrent yeast infections.

Evidence: Limited

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

No known interaction with vaccines. Continue with your regular vaccination schedule.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

Carry this medicine in its original packaging with the prescription label. Keep it in your carry-on luggage to avoid extreme temperatures. Bring a copy of your prescription in case of customs checks. If traveling across time zones, continue with your regular schedule. Store at room temperature and protect from moisture.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 32-year-old woman with recurrent vaginal yeast infections
She was prescribed this medicine as a single dose. She inserted it at bedtime and noticed significant relief from itching within two days. She completed the treatment as directed and avoided intercourse for a week.
💡 Lesson: Proper insertion and adherence to the single-dose regimen can effectively resolve vaginal yeast infections.
👤 A 28-year-old pregnant woman in her second trimester
She developed a vaginal yeast infection and was advised by her doctor to use this medicine. She used it as a single dose and experienced mild burning that resolved quickly. Her infection cleared without complications.
💡 Lesson: This medicine can be safe in pregnancy when used under medical supervision.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: Symptom relief may begin within 1-2 days, but complete resolution may take up to 7 days.

Q: Can I use this medicine during my period?

A: It is best to avoid using this medicine during your period as it may be washed out. Consult your doctor for alternative timing.

Q: Is it safe to use this medicine while pregnant?

A: Clotrimazole is considered safe during pregnancy when used as directed. Consult your doctor before use.

Q: Can I have sex while using this medicine?

A: It is recommended to avoid sexual intercourse during treatment to prevent irritation and reinfection.

Q: What should I do if I miss a dose?

A: If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose. Do not double the dose.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my kidney function?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?

🔄 Substitutes for glenmark clotrimazole 1 vaginal tablet

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: This medicine can be taken orally.
    Fact: This medicine is for vaginal use only and should not be swallowed.
  • Myth: You can stop treatment once symptoms improve.
    Fact: Complete the full course as prescribed to prevent recurrence.

🔄 Alternative Options

Generic Alternatives

  • Clotrimazole vaginal tablet

Brand Alternatives

  • Candid-V
  • Canesten
  • Clotrimazole Vaginal Tablet

📊 Comparison with Similar Medicines

[{"medicine":"Clotrimazole vaginal tablet","class":"Azole antifungal","route":"Vaginal","typical_dose":"500mg single dose","notes":"Local treatment, minimal systemic absorption."},{"medicine":"Fluconazole oral tablet","class":"Azole antifungal","route":"Oral","typical_dose":"150mg single dose","notes":"Systemic treatment, requires prescription."}]

😊 Was this information helpful?

Browse Medicines A-Z

A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
Back to Medicines Directory