genericart diltiazem hydrochloride 60mg tablet - Diltiazem (60mg) medicine

Diltiazem 60mg Sustained-Release Tablet: Complete Medicine Guide

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🏭 Swast Aushadhi Seva Generic Medicine Store 📦 Varies by brand 💊 Allopathy 📅 Updated: Sep 25, 2026
⚠️ Hepatotoxicity Risk 📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: High level of evidence from randomized controlled trials and meta-analyses supporting its use in hypertension and angina.
Reviewed by
SaathiMed Expert Panel | Sep 25, 2026
🩺
Medically Fact-Checked & Clinically Verified by SaathiMed Clinical Review Board
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026

When to Call Your Doctor IMMEDIATELY

  • Fainting or severe dizziness
  • Chest pain that worsens or is not relieved by rest
  • Difficulty breathing or sudden weight gain
  • Slow or irregular heartbeat
  • Yellowing of skin or eyes (jaundice)
  • Severe abdominal pain or vomiting
  • Swelling of face, lips, or throat

If experiencing severe symptoms, call emergency services immediately.

What is genericart diltiazem hydrochloride 60mg tablet used for?

Diltiazem 60 mg sustained-release tablet is a calcium channel blocker used to treat high blood pressure and chest pain (angina). It works by relaxing blood vessels and slowing the heart rate, reducing the heart's workload. It is taken orally, usually once or twice daily, and should not be crushed or chewed.

  • Generic Name: Diltiazem (60mg)
  • Manufacturer: Swast Aushadhi Seva Generic Medicine Store
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 genericart diltiazem hydrochloride 60mg tablet के बारे में (Hindi Summary)

उपयोग: यह दवा उच्च रक्तचाप (हाइपरटेंशन) और एंजाइना (सीने में दर्द) के इलाज के लिए इस्तेमाल की जाती है। यह रक्त वाहिकाओं को आराम देकर और हृदय की गति को धीमा करके हृदय पर दबाव कम करती है। यह दिल की धड़कन की कुछ समस्याओं में भी उपयोगी हो सकती है।

साइड इफेक्ट्स: आम दुष्प्रभावों में सिरदर्द, चक्कर आना, थकान, मतली और पैरों में सूजन शामिल हैं। गंभीर दुष्प्रभाव दुर्लभ हैं लेकिन धीमी हृदय गति, निम्न रक्तचाप, या यकृत की समस्या हो सकती है। यदि आपको बेहोशी, सीने में दर्द, या सांस लेने में कठिनाई हो तो तुरंत डॉक्टर से संपर्क करें।

सुरक्षा सलाह: इस दवा को डॉक्टर के निर्देशानुसार ही लें। गोली को चबाएं या तोड़ें नहीं, पूरा निगल लें। शराब से बचें क्योंकि इससे चक्कर और निम्न रक्तचाप बढ़ सकता है। डॉक्टर की सलाह के बिना दवा अचानक बंद न करें। नियमित रूप से रक्तचाप और हृदय गति की जांच कराएं।

💡 Did You Know? The Indian pharmaceutical market is expected to reach $130 billion by 2030.

💊 genericart diltiazem hydrochloride 60mg tablet Uses & Benefits

[{"condition":"Hypertension","description":"Lowers blood pressure by relaxing blood vessels, reducing the risk of stroke and heart attack.","evidence":"Well-established"},{"condition":"Chronic stable angina","description":"Reduces the frequency and severity of chest pain by improving blood flow to the heart and decreasing its workload.","evidence":"Well-established"},{"condition":"Vasospastic angina (Prinzmetal's angina)","description":"Helps prevent coronary artery spasms that cause chest pain at rest.","evidence":"Well-established"},{"condition":"Atrial fibrillation or flutter","description":"Used to control heart rate in certain patients with rapid atrial arrhythmias.","evidence":"Established"},{"condition":"Post-myocardial infarction protection","description":"May be used to reduce the risk of further heart events after a heart attack, especially when beta-blockers are not suitable.","evidence":"Established"}]

Off-label uses: [{"condition":"Migraine prophylaxis","description":"Sometimes prescribed off-label to prevent migraines, though evidence is limited.","evidence":"Limited"},{"condition":"Raynaud's phenomenon","description":"May help reduce frequency and severity of Raynaud's attacks by improving circulation.","evidence":"Limited"}]

Primary treatment for: Hypertension

Also treats: Chronic stable angina, Vasospastic angina, Atrial fibrillation/flutter, Post-myocardial infarction

📋 Drug Information

Generic Name(s)Diltiazem (60mg)
Brand Namegenericart diltiazem hydrochloride 60mg tablet
ManufacturerSwast Aushadhi Seva Generic Medicine Store
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassCARDIAC
Action ClassCalcium channel blockers- Nondihydropyridines
Route of AdministrationOral
StorageStore at room temperature between 15°C and 30°C (59°F to 86°F). Protect from light and moisture. Keep in the original container, tightly closed.
Shelf Life24 months from the date of manufacture.
WHO GuidelineThe World Health Organization includes calcium channel blockers like diltiazem as one of the first-line drug classes for the treatment of hypertension in adults, especially in certain populations. However, specific recommendations may vary based on individual patient factors.
ICMR GuidelineThe Indian Council of Medical Research (ICMR) guidelines for hypertension management include calcium channel blockers as first-line therapy, either alone or in combination with other antihypertensives. Diltiazem is among the recommended options.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Take this medicine at the same time each day to maintain consistent blood levels.
2
Swallow the sustained-release tablet whole; do not crush, chew, or break it.
3
Monitor your blood pressure and heart rate regularly and keep a log to share with your doctor.
4
Avoid grapefruit juice and alcohol while taking this medicine.
5
Do not stop this medicine abruptly; your doctor will taper the dose gradually if needed.
6
Report any unusual swelling, weight gain, or difficulty breathing to your doctor promptly.
7
Use caution when driving or operating machinery until you know how this medicine affects you.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅
High blood pressure
This medicine is commonly prescribed for this.
Likely Use
✅
Chest pain (angina)
This medicine helps prevent angina attacks.
Likely Use
❌
Fever
This medicine is not a fever reducer.
Not Primary
❌
Headache
This medicine is not a primary headache treatment.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionDiltiazem is well absorbed from the gastrointestinal tract after oral administration. The sustained-release formulation is designed to release the drug slowly, but absorption may be affected by food. Taking with food may increase bioavailability.
DistributionDiltiazem is widely distributed throughout the body tissues. It crosses the placenta and is excreted in breast milk. The volume of distribution is approximately 3-5 L/kg.
Protein BindingApproximately 70-80% bound to plasma proteins.
MetabolismExtensively metabolized in the liver by cytochrome P450 enzymes, primarily CYP3A4, through deacetylation, N-demethylation, and O-demethylation. The main active metabolite is desacetyldiltiazem, which has about 25-50% of the potency of the parent drug.
Half-LifeThe elimination half-life of diltiazem is approximately 3-4.5 hours for immediate-release formulations, but for sustained-release formulations, the apparent half-life is longer, typically 5-8 hours, allowing for less frequent dosing.
ExcretionDiltiazem and its metabolites are primarily excreted in the urine (about 60%) and feces (about 35%). Only a small amount is excreted unchanged.
BioavailabilityThe oral bioavailability of diltiazem is approximately 40% due to extensive first-pass metabolism. The sustained-release formulation may have a slightly different bioavailability profile.
Onset of ActionFor immediate-release formulations, onset of action is within 30-60 minutes. For sustained-release, the onset is slower, typically within 1-2 hours, but the effect is more gradual.
Peak Plasma TimeFor sustained-release tablets, peak plasma concentration is usually reached in 4-6 hours after oral administration.
Duration of ActionThe antihypertensive and antianginal effects of sustained-release diltiazem last approximately 12-24 hours, depending on the specific formulation and individual patient factors.

How It Works

Diltiazem inhibits the influx of calcium ions into vascular smooth muscle cells and cardiac muscle cells by blocking L-type calcium channels. This leads to relaxation of blood vessels (vasodilation) and a decrease in heart rate and contractility, thereby reducing myocardial oxygen demand and lowering blood pressure.

Mechanism Steps

1
Calcium channel blockade: Diltiazem binds to the L-type calcium channels on the cell membrane of vascular smooth muscle and cardiac cells.
2
Reduced calcium influx: This binding reduces the entry of calcium ions into the cells during depolarization.
3
Vascular smooth muscle relaxation: Decreased intracellular calcium leads to relaxation of vascular smooth muscle, causing vasodilation and reduced peripheral resistance.
4
Cardiac effects: In the heart, reduced calcium influx slows the heart rate, decreases contractility, and slows conduction through the AV node.
5
Clinical outcome: The combined effects lower blood pressure, reduce myocardial oxygen demand, and improve coronary blood flow, relieving angina.

💡 How to Take genericart diltiazem hydrochloride 60mg tablet

Strength: Sustained-release tablet, 60 mg

1Swallow the tablet whole with a glass of water.
2Do not crush, chew, or break the sustained-release tablet.
3Take at the same time each day, preferably with food to reduce stomach upset.
4If you miss a dose, follow the missed dose instructions.
5Do not stop taking this medicine suddenly without consulting your doctor.

Dosage Information

Adult DosageThe usual adult dose for hypertension is 180-240 mg once daily as a sustained-release formulation, but may be adjusted to 120-360 mg daily in divided doses. For angina, the typical dose is 120-180 mg once daily. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function, and response to therapy. Do not crush or chew the sustained-release tablet; swallow it whole.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageElderly patients may be more sensitive to the effects of diltiazem, especially bradycardia and hypotension. Start with a lower dose and titrate slowly. Monitor renal and hepatic function regularly.
Renal ImpairmentNo specific dose adjustment is provided in the manufacturer's labeling for renal impairment. However, diltiazem and its metabolites are excreted by the kidneys, so caution is advised. Monitor renal function and adjust dose as needed.
Hepatic ImpairmentIn patients with hepatic impairment, diltiazem should be started at a lower dose and titrated slowly. Monitor liver function tests regularly.
Maximum Daily DoseThe maximum recommended daily dose is 360 mg for hypertension and 360 mg for angina, but doses above 240 mg/day are rarely used. Individualize as per clinical response.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With food
Take with meals
Reduces stomach upset and may improve absorption consistency.
Grapefruit
Avoid
May increase drug levels and risk of side effects.
Alcohol
Avoid
May enhance dizziness and low blood pressure.

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of genericart diltiazem hydrochloride 60mg tablet

✅ Common Side Effects

Headache (Common (5-10%))
Usually resolves on its own. If persistent or severe, consult your doctor.
Dizziness (Common (5-10%))
Avoid driving or operating machinery until you know how it affects you. Rise slowly from sitting or lying positions.
Fatigue (Common (5-10%))
Get adequate rest. If fatigue interferes with daily activities, consult your doctor.
Nausea (Common (5-10%))
Take with food to reduce stomach upset. If nausea persists, consult your doctor.
Peripheral edema (swelling of ankles/feet) (Common (5-10%))
Elevate your legs when sitting. If swelling is severe or sudden, contact your doctor.

🚨 Serious Side Effects

Symptomatic bradycardia (slow heart rate) (Uncommon (0.1-1%))
Seek immediate medical attention if you experience fainting, severe dizziness, or unusual tiredness.
Hypotension (low blood pressure) (Uncommon (0.1-1%))
If you feel lightheaded, faint, or have blurred vision, lie down and seek medical help.
Worsening heart failure (Rare (<0.1%))
Report sudden weight gain, swelling, or difficulty breathing to your doctor immediately.
Hepatotoxicity (liver injury) (Rare (<0.1%))
Seek medical attention if you notice yellowing of skin or eyes, dark urine, or severe abdominal pain.
Severe allergic reactions (angioedema, anaphylaxis) (Rare (<0.1%))
Call emergency services if you experience swelling of face, lips, throat, or difficulty breathing.

⚠️ Rare Side Effects

Gingival hyperplasia
Maintain good oral hygiene and consult a dentist if gums become swollen or bleed.
Photosensitivity
Use sunscreen and protective clothing when outdoors.
Thrombocytopenia
Report unusual bruising or bleeding to your doctor.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Beta-blockers Major
Digoxin Major
CYP3A4 inhibitors Major
CYP3A4 inducers Major
Statins Major
Cyclosporine Moderate
Carbamazepine Moderate
Midazolam Moderate
Rifampin Moderate
Cimetidine Minor

🚨 Major Interactions

  • Beta-blockers (e.g., propranolol, metoprolol)
  • Digoxin
  • CYP3A4 inhibitors (e.g., ketoconazole, itraconazole, ritonavir, clarithromycin)
  • CYP3A4 inducers (e.g., rifampin, carbamazepine, phenytoin)
  • Statins (e.g., simvastatin, atorvastatin)

⚡ Moderate Interactions

  • Cyclosporine
  • Carbamazepine
  • Midazolam
  • Rifampin

🍷 Alcohol Interaction

Alcohol may enhance the blood pressure-lowering and dizziness effects of diltiazem. It is advisable to avoid or limit alcohol consumption while taking this medicine.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Known hypersensitivity to diltiazem or any component of the formulation","Sick sinus syndrome (unless a functioning pacemaker is present)","Second- or third-degree AV block (unless a functioning pacemaker is present)","Severe hypotension (systolic BP

⚠️ Warnings & Precautions

["Use with caution in patients with impaired liver or kidney function; dose adjustment may be required.","May cause drowsiness or dizziness; avoid driving or operating machinery until effects are known.","Do not abruptly discontinue; taper gradually under medical supervision.","Use with caution in elderly patients; start at lower doses.","May worsen heart failure; monitor for signs of fluid retention.","Avoid grapefruit juice as it can increase drug levels.","Inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding."]

🤱 Lactation Safety

Diltiazem is excreted in human breast milk. Because of the potential for serious adverse reactions in nursing infants, a decision should be made whether to discontinue nursing or discontinue the drug, taking into account the importance of the drug to the mother.

💊 Overdose Management

Overdose of diltiazem can cause severe hypotension, bradycardia, heart block, and cardiac arrest. Treatment is supportive and symptomatic. Gastric lavage may be considered if ingestion is recent. Intravenous calcium gluconate or calcium chloride may be used to reverse calcium channel blockade. Atropine, vasopressors, and cardiac pacing may be required. Seek immediate medical attention.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up.

Additional Safety Advice

General Safety

Take this medicine exactly as prescribed. Do not crush, chew, or break the sustained-release tablet; swallow it whole. Avoid alcohol as it may increase dizziness and low blood pressure. Do not stop this medicine suddenly without consulting your doctor, as it may worsen angina or blood pressure. Inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding. Regular monitoring of blood pressure, heart rate, and liver function may be required. Use caution while driving or operating machinery until you know how this medicine affects you.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients are more sensitive to the blood pressure-lowering and heart rate-slowing effects of diltiazem. Start with a lower dose and titrate slowly. Monitor renal and hepatic function regularly. Falls due to dizziness are a concern; take precautions.

🤰 Pregnancy Planning (TTC)

If you are planning to become pregnant, consult your doctor. Diltiazem is Pregnancy Category C and should be used only if the potential benefit justifies the potential risk. Your doctor may switch you to a safer alternative.

🏥 Post-Surgery Considerations

Inform your surgeon and anesthesiologist that you are taking diltiazem. It may interact with anesthesia and other medications used during surgery. Your doctor may advise temporary discontinuation or dose adjustment.

🦷 Dental Procedures

Inform your dentist that you are taking diltiazem, especially if you are undergoing procedures that may cause bleeding or require anesthesia. Diltiazem can cause gingival hyperplasia, so maintain good oral hygiene.

💚 Lifestyle Tips for Better Results

🏃
Maintain a healthy weight to reduce strain on your heart.
🥗
Engage in regular moderate exercise like walking or swimming, as advised by your doctor.
😴
Follow a heart-healthy diet low in sodium and saturated fats.
💧
Limit alcohol and avoid smoking.
🧘
Manage stress through relaxation techniques like deep breathing or meditation.
🌞
Get adequate sleep and practice good sleep hygiene.

🏋️ Exercise Considerations

Moderate exercise is generally safe and beneficial, but avoid sudden strenuous activities until you know how this medicine affects you. If you experience dizziness, chest pain, or shortness of breath during exercise, stop and consult your doctor.

🥗 Diet Recommendations

Include plenty of fruits, vegetables, and whole grains.
Choose lean proteins and healthy fats.
Reduce salt intake to help control blood pressure.
Avoid grapefruit and grapefruit juice.
Stay well hydrated unless otherwise advised.

💼 Impact on Daily Work & Life

This medicine may cause dizziness or fatigue, especially when you first start taking it. Avoid driving or operating heavy machinery until you know how it affects you. Most people can continue their normal activities with some adjustments.

🛑 When to Stop This Medicine

Do not stop this medicine without consulting your doctor. If you experience serious side effects or your doctor decides to discontinue, the dose will be tapered gradually to prevent rebound effects.

📅 Long-Term Use Effects

Long-term use of diltiazem is generally safe when monitored appropriately. Regular check-ups should include blood pressure, heart rate, and liver function tests. Some patients may develop tolerance or need dose adjustments. It is important to continue lifestyle modifications and attend follow-up appointments.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Lifestyle modifications

Diet, exercise, weight loss, and stress reduction can help manage hypertension and angina.

Evidence: Well-established
Other antihypertensive medications

ACE inhibitors, ARBs, beta-blockers, or diuretics may be alternatives based on individual needs.

Evidence: Well-established
Angioplasty or bypass surgery

For severe coronary artery disease, invasive procedures may be necessary.

Evidence: Well-established

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

No specific interactions between diltiazem and vaccines are known. However, always inform your healthcare provider about all medicines you are taking before receiving any vaccine.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

Carry this medicine in its original packaging with a copy of your prescription. Keep it in your carry-on luggage to avoid loss or temperature extremes. If traveling across time zones, consult your doctor about adjusting dosing times. Store at room temperature and avoid direct sunlight. Check customs regulations for carrying prescription medicines.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 55-year-old man with a history of high blood pressure and angina
He was prescribed this medicine 60 mg once daily. After two weeks, his blood pressure stabilized, and he experienced fewer angina attacks. He initially felt dizzy but it subsided after a few days. He was advised to avoid grapefruit juice and to monitor his heart rate.
💡 Lesson: Consistent daily dosing and lifestyle modifications significantly improve outcomes. Mild side effects often diminish with continued use.
👤 A 62-year-old woman with atrial fibrillation
She was started on this medicine to control her heart rate. Her palpitations decreased, but she developed ankle swelling. Her doctor reduced the dose and added a diuretic. She was advised to elevate her legs and monitor weight.
💡 Lesson: Dose adjustment and additional measures can manage side effects effectively. Regular follow-up is essential.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: This medicine starts lowering blood pressure within a few hours, but full therapeutic effect may take 2-4 weeks of regular use.

Q: Can I stop taking this medicine if I feel better?

A: No, do not stop without consulting your doctor. High blood pressure often has no symptoms, and stopping suddenly can cause rebound hypertension or angina.

Q: What should I do if I miss a dose?

A: If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose.

Q: Are there any food restrictions?

A: Avoid grapefruit juice as it can increase drug levels. Limit alcohol as it may enhance side effects like dizziness.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my kidney function?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?
  • Is it safe during pregnancy?
  • What are the withdrawal effects?

🔄 Substitutes for genericart diltiazem hydrochloride 60mg tablet

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: Diltiazem is a blood thinner.
    Fact: Diltiazem is not a blood thinner; it is a calcium channel blocker that relaxes blood vessels and slows the heart rate.
  • Myth: You can stop diltiazem once your blood pressure is normal.
    Fact: High blood pressure often has no symptoms, and stopping medication can cause dangerous rebound hypertension. Always consult your doctor before stopping.
  • Myth: Diltiazem can be taken with grapefruit juice.
    Fact: Grapefruit juice can increase diltiazem levels and side effects. It is best to avoid grapefruit juice while on this medicine.

🔄 Alternative Options

Generic Alternatives

  • Diltiazem sustained-release tablets are available as generics from various manufacturers.

Brand Alternatives

  • Dilzem SR
  • Diltia
  • Angizem
  • Dilcontin
  • Diltiazem SR

📊 Comparison with Similar Medicines

[{"medicine":"Diltiazem","class":"Calcium channel blocker (benzothiazepine)","primary_use":"Hypertension, angina","common_side_effects":"Headache, dizziness, edema"},{"medicine":"Amlodipine","class":"Calcium channel blocker (dihydropyridine)","primary_use":"Hypertension, angina","common_side_effects":"Edema, flushing, headache"},{"medicine":"Verapamil","class":"Calcium channel blocker (phenylalkylamine)","primary_use":"Hypertension, angina, arrhythmias","common_side_effects":"Constipation, dizziness, bradycardia"},{"medicine":"Metoprolol","class":"Beta-blocker","primary_use":"Hypertension, angina, heart failure","common_side_effects":"Fatigue, bradycardia, cold extremities"}]

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