gaticon-f eye drop - Flurbiprofen (0.03% w/v) + Gatifloxacin (0.3% w/v) medicine

Flubigat Eye Drop: Complete Medicine Guide

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🏭 Maa Enterprise 📦 Varies by brand 💊 Allopathy 📅 Updated: Oct 22, 2026
📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Moderate to well-established for approved indications.
Reviewed by
SaathiMed Expert Panel | Oct 22, 2026
🩺
Medically Fact-Checked & Clinically Verified by SaathiMed Clinical Review Board
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026

When to Call Your Doctor IMMEDIATELY

  • Sudden decrease in vision
  • Severe eye pain that does not improve
  • Swelling of face, lips, or throat
  • Signs of allergic reaction such as rash or itching
  • Persistent redness or discharge that worsens
  • Eye injury or foreign body sensation

If experiencing severe symptoms, call emergency services immediately.

What is gaticon-f eye drop used for?

This medicine is a combination eye drop containing flurbiprofen (an anti-inflammatory) and gatifloxacin (an antibiotic). It is used to treat bacterial eye infections and reduce inflammation after eye surgery.

  • Generic Name: Flurbiprofen (0.03% w/v) + Gatifloxacin (0.3% w/v)
  • Manufacturer: Maa Enterprise
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 gaticon-f eye drop के बारे में (Hindi Summary)

उपयोग: यह दवा आंखों की बैक्टीरियल संक्रमण और सूजन के इलाज के लिए इस्तेमाल की जाती है। इसमें फ्लर्बिप्रोफेन (सूजन कम करने वाला) और गैटीफ्लोक्सासिन (एंटीबायोटिक) होता है। यह आंखों की सर्जरी के बाद भी लगाई जाती है।

साइड इफेक्ट्स: आम दुष्प्रभावों में आंखों में जलन, लालिमा, धुंधली दृष्टि और असुविधा शामिल हैं। गंभीर दुष्प्रभाव दुर्लभ हैं लेकिन एलर्जी, कॉर्निया की क्षति या संक्रमण बढ़ सकता है। किसी भी असामान्य लक्षण पर डॉक्टर से संपर्क करें।

सुरक्षा सलाह: इस दवा को केवल आंखों में डालें। ड्रॉपर की नोक को किसी सतह से न छुएं। उपयोग से पहले और बाद में हाथ धोएं। कॉन्टैक्ट लेंस पहनने से पहले हटा दें और 15 मिनट बाद ही पहनें। डॉक्टर की सलाह के बिना लंबे समय तक उपयोग न करें।

💡 Did You Know? India is the largest provider of generic medicines globally, supplying over 50% of global vaccine demand.

💊 gaticon-f eye drop Uses & Benefits

[{"condition":"Post-operative ocular inflammation and infection prophylaxis","description":"Used after cataract or refractive surgery to prevent bacterial infection and reduce inflammation.","evidence":"Well-established"},{"condition":"Bacterial conjunctivitis with associated inflammation","description":"Treats bacterial conjunctivitis while reducing inflammatory symptoms such as redness and discomfort.","evidence":"Well-established"},{"condition":"Corneal ulcers","description":"Used in the management of bacterial corneal ulcers to eradicate infection and control inflammation.","evidence":"Moderate"},{"condition":"Blepharitis or blepharoconjunctivitis","description":"May be prescribed when bacterial infection and inflammation coexist.","evidence":"Limited"}]

Off-label uses: [{"condition":"Prevention of cystoid macular edema after cataract surgery","description":"Some clinicians use topical NSAIDs like flurbiprofen for this purpose, but evidence is not robust for the combination product.","evidence":"Limited"}]

Primary treatment for: Bacterial eye infections with inflammation

Also treats: Post-operative ocular inflammation, Bacterial conjunctivitis, Corneal ulcers

📋 Drug Information

Generic Name(s)Flurbiprofen (0.03% w/v) + Gatifloxacin (0.3% w/v)
Brand Namegaticon-f eye drop
ManufacturerMaa Enterprise
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassOPHTHAL
Action Class
Route of AdministrationOphthalmic
StorageStore at room temperature (15-30°C). Protect from light and freezing. Keep the bottle tightly closed when not in use.
Shelf Life24 months from the date of manufacture, or as printed on the packaging.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Always wash your hands before and after applying this eye drop.
2
Do not touch the dropper tip to your eye or any surface to avoid contamination.
3
Remove contact lenses before use and wait at least 15 minutes before reinserting.
4
Use the drops at evenly spaced intervals as prescribed by your doctor.
5
Complete the full course even if symptoms improve to prevent recurrence.
6
Report any worsening pain, redness, or vision changes immediately.
7
Store the bottle tightly closed at room temperature and protect from light.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅
Eye redness and discharge
This medicine is commonly prescribed for bacterial eye infections.
Likely Use
✅
Eye pain after surgery
Used to reduce inflammation and prevent infection post-operatively.
Likely Use
❌
Dry eye
This medicine is not a lubricant and is not used for dry eye.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionSystemic absorption after topical ocular administration is minimal but can occur, especially if the nasolacrimal duct is not compressed after instillation. Flurbiprofen and gatifloxacin may be detected in plasma at low levels.
DistributionNot established from the available information for ocular route.
Protein BindingFlurbiprofen is highly protein-bound (>99%) in plasma. Gatifloxacin is approximately 20% protein-bound.
MetabolismFlurbiprofen is metabolized in the liver primarily by CYP2C9. Gatifloxacin undergoes minimal metabolism.
Half-LifeFlurbiprofen plasma half-life is approximately 3-6 hours. Gatifloxacin half-life is approximately 7-14 hours.
ExcretionFlurbiprofen is excreted in urine as metabolites and unchanged drug. Gatifloxacin is primarily excreted unchanged in urine.
BioavailabilitySystemic bioavailability after ocular administration is low but not precisely established.
Onset of ActionAnti-inflammatory effects may begin within 30 minutes to 1 hour after instillation. Antibacterial effects begin immediately upon contact with susceptible bacteria.
Peak Plasma TimeNot established from the available information for ocular route.
Duration of ActionAnti-inflammatory effect lasts approximately 4-6 hours; antibacterial effect depends on dosing frequency and bacterial susceptibility.

How It Works

This medicine combines two mechanisms. Flurbiprofen reversibly inhibits cyclooxygenase enzymes (COX-1 and COX-2), reducing the synthesis of prostaglandins that mediate ocular inflammation, pain, and miosis. Gatifloxacin inhibits bacterial DNA gyrase and topoisomerase IV, enzymes essential for DNA replication, transcription, repair, and recombination, leading to bacterial cell death. The combination provides both anti-inflammatory and antibacterial effects in the eye.

Mechanism Steps

1
Flurbiprofen inhibits cyclooxygenase: Flurbiprofen binds to and reversibly inhibits COX-1 and COX-2 enzymes in the eye, blocking the conversion of arachidonic acid to prostaglandin H2.
2
Reduced prostaglandin synthesis: Lower prostaglandin levels decrease vasodilation, vascular permeability, and pain sensitization, leading to reduced ocular inflammation and discomfort.
3
Gatifloxacin enters bacterial cells: Gatifloxacin penetrates bacterial cell walls and inhibits DNA gyrase and topoisomerase IV, enzymes critical for DNA replication and repair.
4
Bacterial cell death: Inhibition of these enzymes leads to double-strand DNA breaks and rapid bacterial cell death, clearing the infection.

💡 How to Take gaticon-f eye drop

Strength: Ophthalmic solution containing flurbiprofen 0.03% w/v and gatifloxacin 0.3% w/v.

1Wash your hands thoroughly with soap and water.
2Shake the bottle gently before use.
3Tilt your head back and pull down your lower eyelid to form a pouch.
4Hold the dropper above the eye and squeeze one drop into the pouch.
5Close your eye gently and press the inner corner near your nose for 1-2 minutes to prevent drainage.
6Do not blink or rub your eye immediately after instillation.
7Wipe off any excess solution with a clean tissue.
8Replace the cap tightly and wash your hands again.

Dosage Information

Adult DosageThe usual adult dose is one drop in the affected eye(s) every 4 to 6 hours, or as directed by your ophthalmologist. For post-operative use, one drop may be instilled four times daily, starting before surgery and continuing for several days after. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician or ophthalmologist.
Elderly DosageNo specific dose adjustment is required for elderly patients, but caution is advised due to potential systemic absorption and age-related organ function decline.
Renal ImpairmentNo dose adjustment is typically required for ocular use, but systemic absorption may occur. Use with caution in severe renal impairment.
Hepatic ImpairmentNo dose adjustment is typically required for ocular use, but systemic absorption may occur. Use with caution in severe hepatic impairment.
Maximum Daily DoseNot established from the available information. Follow your doctor's prescription.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of gaticon-f eye drop

✅ Common Side Effects

Transient stinging or burning (Common (5-10%))
Usually resolves within minutes. If persistent, consult your eye doctor.
Eye redness (Common (5-10%))
May be due to the medicine or underlying condition. Consult if worsening.
Blurred vision (Common (5-10%))
Wait until vision clears before driving or operating machinery.
Foreign body sensation (Common (5-10%))
Usually temporary. If persistent, consult your doctor.

🚨 Serious Side Effects

Severe allergic reaction (anaphylaxis) (Rare (<0.1%))
Seek immediate medical attention if you experience swelling of face, lips, throat, or difficulty breathing.
Corneal thinning or perforation (Rare (<0.1%))
Report persistent eye pain, redness, or vision changes immediately.
Superinfection (Rare (<0.1%))
If symptoms worsen or new symptoms appear, consult your eye doctor.

⚠️ Rare Side Effects

Tendon rupture
Seek medical attention if you experience sudden joint pain or swelling.
Peripheral neuropathy
Report numbness, tingling, or burning in hands or feet.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Warfarin Moderate
Other ocular NSAIDs Major
Topical corticosteroids Moderate

🚨 Major Interactions

  • Other topical ocular NSAIDs
  • Oral anticoagulants (e.g., warfarin)

⚡ Moderate Interactions

  • Other fluoroquinolones
  • Corticosteroids (topical ocular)

🍷 Alcohol Interaction

No known direct interaction with alcohol when used ophthalmically. However, alcohol may worsen dehydration or systemic effects if absorbed. Consult your doctor if you consume alcohol regularly.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Hypersensitivity to flurbiprofen, gatifloxacin, or other fluoroquinolones","Viral, fungal, or mycobacterial eye infections","Use in children under 1 year of age (safety not established)","Wearing contact lenses during treatment (unless approved by doctor)"]

⚠️ Warnings & Precautions

["For ophthalmic use only; not for injection or oral use.","Prolonged use may lead to bacterial or fungal overgrowth.","May cause temporary blurred vision; avoid driving until clear.","Do not touch dropper tip to eye or any surface.","Use with caution in patients with dry eye or corneal disease.","Systemic absorption may occur; use caution in patients with known NSAID or fluoroquinolone sensitivities."]

🤱 Lactation Safety

It is not known whether flurbiprofen or gatifloxacin are excreted in human milk after ocular administration. Systemically, both are excreted in breast milk. Caution is advised; consult your doctor.

💊 Overdose Management

Overdose is unlikely with ocular use. If accidental ingestion occurs, seek medical attention. Symptoms may include nausea, vomiting, and abdominal pain. Treatment is supportive.

⏰ Missed Dose

If you miss a dose, apply it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose.

Additional Safety Advice

General Safety

For ophthalmic use only. Do not touch the dropper tip to any surface to avoid contamination. Wash your hands before and after use. Remove contact lenses before applying and wait at least 15 minutes before reinserting. Do not use if the solution changes color or contains particles. Do not share this medicine with others. Avoid driving or operating machinery if your vision is temporarily blurred after instillation. Inform your doctor if you are pregnant, planning pregnancy, or breastfeeding. Do not use for longer than prescribed without medical supervision. Keep out of reach of children.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients may be more susceptible to systemic effects of fluoroquinolones and NSAIDs. Use with caution and monitor for side effects.

🤰 Pregnancy Planning (TTC)

Consult your doctor before using this medicine if you are pregnant or planning pregnancy. Flurbiprofen should be avoided in the third trimester. Gatifloxacin should be used only if clearly needed.

🏥 Post-Surgery Considerations

This medicine is commonly prescribed after eye surgery to prevent infection and reduce inflammation. Follow your surgeon's instructions carefully.

🦷 Dental Procedures

No specific precautions for dental procedures, but inform your dentist about all medicines you are using.

💚 Lifestyle Tips for Better Results

🏃
Avoid touching or rubbing your eyes.
🥗
Wash your hands frequently, especially before applying the drops.
😴
Do not share towels or eye makeup with others.
💧
Follow a healthy diet rich in vitamins A, C, and E for eye health.
🧘
Get adequate sleep to support healing.
🌞
Avoid wearing contact lenses until your doctor approves.

🏋️ Exercise Considerations

Avoid swimming or water sports while using this medicine to prevent contamination. Consult your doctor before resuming strenuous activities after eye surgery.

🥗 Diet Recommendations

Include foods rich in vitamin A such as carrots and spinach.
Stay hydrated to maintain tear production.
Limit processed foods and sugary drinks.
Consume omega-3 fatty acids from fish or flaxseed.

💼 Impact on Daily Work & Life

This medicine may cause temporary blurred vision after instillation. Avoid driving or operating heavy machinery until your vision is clear. You can continue most daily activities, but avoid activities that may expose your eyes to dust or contaminants.

🛑 When to Stop This Medicine

Stop using this medicine only when your doctor advises. Do not stop early even if symptoms improve, as this may lead to recurrence or resistance. If you experience serious side effects, stop and seek medical attention immediately.

📅 Long-Term Use Effects

Prolonged use of this medicine may increase the risk of corneal thinning, superinfection, and bacterial resistance. It should only be used for the duration prescribed by your doctor. Regular follow-up with an ophthalmologist is recommended if long-term use is necessary.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Warm compresses

Can help relieve discomfort in bacterial conjunctivitis but does not treat infection.

Evidence: Limited
Lubricating eye drops

May soothe irritation but do not treat infection or inflammation.

Evidence: Well-established for symptom relief

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

No known interaction with vaccines. However, if you are scheduled for vaccination, inform your doctor about this medicine.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

Carry this medicine in its original packaging with a copy of your prescription. Keep it in your carry-on luggage to avoid temperature extremes. Store at room temperature and protect from light. If traveling across time zones, continue your regular dosing schedule as closely as possible. Check customs regulations for carrying prescription medicines.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 60-year-old man after cataract surgery
He was prescribed this medicine four times daily after surgery. He noticed significant reduction in redness and discomfort within three days. He emphasized the importance of not touching the dropper tip and completing the full course.
💡 Lesson: Consistent use and proper technique prevent infection and promote healing after surgery.
👤 A 35-year-old woman with bacterial conjunctivitis
She had redness, discharge, and discomfort in one eye. After using this medicine as prescribed, her symptoms improved in two days. She was advised to avoid sharing towels and to wash hands frequently.
💡 Lesson: Early treatment and hygiene prevent spread of infection to the other eye or to others.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: You may notice improvement in symptoms within 24-48 hours, but complete the full course as prescribed.

Q: Can I use this medicine for allergies?

A: No, this medicine is for bacterial infections and inflammation, not allergic conjunctivitis.

Q: Is it safe to use with other eye drops?

A: Wait at least 5-10 minutes between different eye drops to prevent washing out the previous one.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I use this medicine for more than a week?
  • Will it affect my vision permanently?
  • Can I drive after using this eye drop?
  • Does it interact with my other eye drops?
  • What if I miss a dose?
  • Can I wear contact lenses while using this?

🔄 Substitutes for gaticon-f eye drop

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: This medicine can be used for any eye redness.
    Fact: It is specifically for bacterial infections with inflammation and should only be used as prescribed.
  • Myth: You can stop using it once symptoms improve.
    Fact: You must complete the full course to prevent recurrence and resistance.

📊 Comparison with Similar Medicines

[{"medicine":"Flurbiprofen + Gatifloxacin","class":"NSAID + Fluoroquinolone antibiotic","route":"Ophthalmic","primary_use":"Bacterial infection with inflammation"},{"medicine":"Tobramycin + Dexamethasone","class":"Aminoglycoside + Corticosteroid","route":"Ophthalmic","primary_use":"Bacterial infection with inflammation"}]

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