florocid injection - Sodium Fluoride (1% w/v) + Procaine (2% w/v) medicine

Florocid Injection: Complete Medicine Guide

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🏭 East India Pharmaceutical Works Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Sep 24, 2026
🤰 Pregnancy Category Not established from the available information. Use only if clearly needed and advised by a healthcare professional. 📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Moderate for dental caries prevention; Well-established for local anesthesia.
Reviewed by
SaathiMed Expert Panel | Sep 24, 2026

When to Call Your Doctor IMMEDIATELY

  • Difficulty breathing or swallowing
  • Swelling of the face, lips, or throat
  • Bluish discoloration of lips or skin
  • Severe dizziness or fainting
  • Irregular heartbeat or palpitations
  • Seizures
  • Persistent numbness or weakness in the mouth or face

If experiencing severe symptoms, call emergency services immediately.

What is florocid injection used for?

This medicine is a combination of sodium fluoride and procaine used in dental procedures to provide local anesthesia and prevent tooth decay. It is given as an injection by a dentist or healthcare professional.

  • Generic Name: Sodium Fluoride (1% w/v) + Procaine (2% w/v)
  • Manufacturer: East India Pharmaceutical Works Ltd
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 florocid injection के बारे में (Hindi Summary)

उपयोग: यह दवा दांतों की सड़न रोकने और दांतों के इलाज के दौरान सुन्न करने के लिए इस्तेमाल की जाती है। इसमें सोडियम फ्लोराइड और प्रोकेन दोनों होते हैं। सोडियम फ्लोराइड दांतों की इनेमल को मजबूत बनाता है और कैविटी से बचाता है, जबकि प्रोकेन उस जगह को सुन्न कर देता है जहां इंजेक्शन लगाया जाता है। यह दवा केवल डॉक्टर या दंत चिकित्सक द्वारा ही दी जाती है। इसे घर पर खुद से नहीं लगाया जाना चाहिए।

साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में इंजेक्शन की जगह पर दर्द, लालिमा या सूजन, हल्का चक्कर आना, और मुंह या चेहरे का सुन्न होना शामिल है। कुछ लोगों को मतली या मुंह में धातु जैसा स्वाद भी आ सकता है। गंभीर दुष्प्रभाव दुर्लभ हैं, लेकिन एलर्जी, सांस लेने में कठिनाई, या ब्लड प्रेशर में अचानक गिरावट हो सकती है। अगर आपको कोई असामान्य लक्षण दिखे तो तुरंत डॉक्टर को बताएं।

सुरक्षा सलाह: यह दवा केवल योग्य डॉक्टर या दंत चिकित्सक द्वारा ही दी जानी चाहिए। इंजेक्शन लगवाने से पहले अपने डॉक्टर को बताएं कि आपको प्रोकेन या किसी अन्य सुन्न करने वाली दवा से एलर्जी है या नहीं। अगर आपको दिल, लीवर, किडनी या खून से जुड़ी कोई बीमारी है, या आप गर्भवती या स्तनपान करा रही हैं, तो भी डॉक्टर को जरूर बताएं। इंजेक्शन के बाद कम से कम 2-3 घंटे तक गाड़ी न चलाएं और मशीन न चलाएं। जब तक मुंह का सुन्नपन पूरी तरह खत्म न हो जाए, तब तक कुछ न खाएं-पिएं।

💡 Did You Know? Over 80% of the antiretroviral drugs used globally to combat AIDS are supplied by Indian pharmaceutical companies.

💊 florocid injection Uses & Benefits

[{"condition":"Dental caries prevention","description":"Used as a professional fluoride application to strengthen tooth enamel and reduce the risk of cavities, especially in high-risk patients.","evidence":"Well-established"},{"condition":"Local anesthesia for dental procedures","description":"Procaine provides temporary numbness for minor dental procedures such as fillings, extractions, or scaling.","evidence":"Well-established"},{"condition":"Dentinal hypersensitivity","description":"Fluoride application helps reduce sensitivity in exposed dentin by occluding dentinal tubules.","evidence":"Moderate"}]

Off-label uses: [{"condition":"Treatment of oral lichen planus","description":"Sometimes used off-label for symptomatic relief of oral lichen planus due to anti-inflammatory effects of procaine and fluoride.","evidence":"Limited"}]

Primary treatment for: Dental caries

Also treats: Dentinal hypersensitivity, Oral lichen planus

📋 Drug Information

Generic Name(s)Sodium Fluoride (1% w/v) + Procaine (2% w/v)
Brand Nameflorocid injection
ManufacturerEast India Pharmaceutical Works Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassANTI INFECTIVES
Action Class
Route of AdministrationParenteral (injection)
StorageStore in a cool, dry place, protected from light. Do not freeze. Keep in the original container.
Shelf Life24 months from the date of manufacture.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Always aspirate before injecting to avoid intravascular administration.
2
Use the smallest effective dose to minimize the risk of systemic toxicity.
3
Monitor patients with a history of methemoglobinemia or cardiac disease closely.
4
Advise patients not to eat or drink until the numbness has completely resolved.
5
Document any allergic reactions and avoid re-exposure.
6
Consider alternative local anesthetics in patients with pseudocholinesterase deficiency.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

Tooth sensitivity
This medicine is used to reduce tooth sensitivity.
Likely Use
Dental cavity
This medicine helps prevent and treat early cavities.
Likely Use
Toothache
This medicine is not a primary painkiller for toothache.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionProcaine is rapidly absorbed from the injection site into the bloodstream. Sodium fluoride is also absorbed, but its systemic absorption is limited when given as a local dental injection. The exact absorption kinetics are not established from the available information.
DistributionProcaine distributes widely into body tissues after absorption. Sodium fluoride is taken up by teeth and bones. The volume of distribution for procaine is not established from the available information.
Protein BindingProcaine is approximately 5-10% bound to plasma proteins. The protein binding of sodium fluoride is not established from the available information.
MetabolismProcaine is hydrolyzed by plasma pseudocholinesterase to para-aminobenzoic acid (PABA) and diethylaminoethanol. Sodium fluoride is not metabolized and is excreted unchanged.
Half-LifeThe elimination half-life of procaine is very short, approximately 40-84 seconds in plasma. The half-life of sodium fluoride is not established from the available information.
ExcretionProcaine metabolites are excreted mainly in urine. Sodium fluoride is excreted primarily in urine, with some excretion in feces and sweat.
BioavailabilityBioavailability of procaine from the injection site is high but variable. The bioavailability of sodium fluoride from this injection is not established from the available information.
Onset of ActionLocal anesthesia from procaine begins within 2-5 minutes after injection. Fluoride effects on enamel are not immediate and develop over time with repeated applications.
Peak Plasma TimePeak plasma concentration of procaine occurs within a few minutes after injection. The peak plasma time for sodium fluoride is not established from the available information.
Duration of ActionLocal anesthesia from procaine typically lasts 30-60 minutes. The duration of fluoride's effect on enamel is long-lasting, as it becomes incorporated into the tooth structure.

How It Works

This medicine works through two main components. Sodium fluoride acts on tooth enamel by promoting remineralization and forming fluorapatite, which is more resistant to acid attacks from bacteria. It also inhibits bacterial enzymes involved in carbohydrate metabolism, reducing acid production. Procaine is a local anesthetic of the ester type. It blocks sodium channels in nerve cell membranes, preventing the generation and conduction of nerve impulses. This results in reversible loss of sensation in the area where it is injected. The combination allows for painless delivery of fluoride to the target site.

Mechanism Steps

1
Sodium channel blockade by procaine: Procaine binds to voltage-gated sodium channels on nerve membranes, preventing sodium influx and blocking nerve impulse transmission.
2
Loss of sensation: The blockade of sodium channels results in reversible loss of pain and touch sensation in the injected area.
3
Fluoride uptake by enamel: Sodium fluoride reacts with hydroxyapatite in tooth enamel to form fluorapatite, which is more acid-resistant.
4
Inhibition of bacterial enzymes: Fluoride inhibits enolase and other enzymes in oral bacteria, reducing their ability to produce acid from sugars.
5
Remineralization and prevention: The combined effects help repair early enamel lesions and prevent further demineralization, reducing caries risk.

💡 How to Take florocid injection

Strength: Injection containing Sodium Fluoride 1% w/v and Procaine 2% w/v.

1This medicine is given by a healthcare professional as an injection.
2You will be asked to sit or lie down comfortably.
3The injection site will be cleaned with an antiseptic.
4The injection is given slowly into the appropriate area.
5You may feel a slight pinch or burning during injection.
6After the injection, remain seated for a few minutes.
7Do not eat or drink until the numbness has completely worn off.
8Avoid touching your mouth or face while numb to prevent injury.

Dosage Information

Adult DosageThe dose of this medicine is determined by the healthcare professional based on the specific dental procedure and the patient's condition. It is typically given as a single injection for local anesthesia and fluoride application. The exact volume and concentration used depend on the site and extent of the procedure. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageElderly patients may be more sensitive to the effects of procaine. Use with caution and monitor for dizziness, confusion, or cardiac effects. Dose must be individualized by a qualified clinician.
Renal ImpairmentCaution is advised in patients with severe renal impairment. Sodium fluoride is excreted by the kidneys, and accumulation may occur. Dose adjustment may be necessary. Consult a healthcare professional.
Hepatic ImpairmentCaution is advised in patients with severe hepatic impairment. Procaine is metabolized in the liver, and reduced metabolism may increase the risk of toxicity. Dose adjustment may be necessary. Consult a healthcare professional.
Maximum Daily DoseNot established from the available information. The maximum dose is determined by the healthcare professional based on the procedure and patient factors.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

Eating after injection
Wait until numbness wears off
Prevents choking or biting your cheek.
Drinking hot beverages
Avoid until numbness wears off
May cause burns if you cannot feel the temperature.

⏰ What to Do If You Miss a Dose

📌 This medicine is given as a single dose by a healthcare professional.
→ Missed dose instructions are not applicable.
💡 If you miss your appointment, reschedule with your dentist.

⚠️ Side Effects of florocid injection

✅ Common Side Effects

Injection site pain (Common (5-10%))
Apply a cold compress if needed. It usually resolves within a day.
Dizziness (Common (5-10%))
Sit or lie down until it passes. Avoid driving or operating machinery.
Nausea (Common (5-10%))
Take slow, deep breaths. It usually subsides quickly.
Metallic taste (Common (5-10%))
Rinse your mouth with water after the numbness wears off.

🚨 Serious Side Effects

Allergic reaction (anaphylaxis) (Rare (<0.1%))
Seek immediate medical attention if you experience rash, swelling, difficulty breathing, or a drop in blood pressure.
Methemoglobinemia (Rare (<0.1%))
Seek immediate medical attention if you notice bluish lips or skin, shortness of breath, or confusion.
Seizures (Rare (<0.1%))
Call emergency services immediately if seizures occur.
Cardiac arrhythmias (Rare (<0.1%))
Seek immediate medical attention if you feel palpitations, chest pain, or fainting.

⚠️ Rare Side Effects

Nerve damage
Report persistent numbness, tingling, or weakness to your doctor.
Tissue necrosis at injection site
Report any severe pain, blistering, or skin discoloration at the injection site.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Sulfonamides Major
Cholinesterase inhibitors Major
Methemoglobinemia-inducing agents Major
Beta-blockers Moderate
Digoxin Moderate
Antihistamines Minor

🚨 Major Interactions

  • Sulfonamides
  • Cholinesterase inhibitors
  • Methemoglobinemia-inducing agents

⚡ Moderate Interactions

  • Beta-blockers
  • Digoxin

🍷 Alcohol Interaction

Alcohol may increase the sedative and dizzy effects of this medicine. It is advisable to avoid alcohol for at least 24 hours after receiving this injection.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Known hypersensitivity to procaine or other ester-type local anesthetics","Known hypersensitivity to sodium fluoride","Patients with methemoglobinemia or a history of methemoglobinemia","Patients with severe heart block or severe cardiac disease","Patients with pseudocholinesterase deficiency","Children under 12 years of age unless specifically advised by a specialist"]

⚠️ Warnings & Precautions

["For professional use only. Not for self-administration.","Do not inject into inflamed or infected areas.","Avoid intravascular injection to prevent systemic toxicity.","Use with caution in patients with epilepsy, heart disease, or liver/kidney disease.","May impair ability to drive or operate machinery; avoid these activities for a few hours after injection.","Do not eat or drink until numbness has worn off to prevent choking.","Keep out of reach of children."]

🤱 Lactation Safety

It is not known whether this medicine passes into breast milk. Consult your doctor before receiving this injection if you are breastfeeding.

💊 Overdose Management

Overdose with this medicine is unlikely when used as directed by a healthcare professional. If excessive dose occurs, it may cause severe central nervous system effects such as seizures, respiratory depression, and cardiac arrest. Treatment is supportive and symptomatic. There is no specific antidote for procaine toxicity. For sodium fluoride overdose, monitor for hypocalcemia and treat with intravenous calcium gluconate if needed. Seek immediate medical attention.

⏰ Missed Dose

This medicine is given as a single dose by a healthcare professional. Missed dose instructions are not applicable.

Additional Safety Advice

General Safety

This medicine must only be given by a qualified healthcare professional in a properly equipped setting. Before receiving this injection, tell your doctor if you have ever had an allergic reaction to procaine, lidocaine, or any other numbing medicine. Also inform them if you have heart problems, liver disease, kidney disease, a blood disorder called methemoglobinemia, or if you are pregnant or breastfeeding. Do not drive or operate heavy machinery for at least a few hours after the injection, as it may cause dizziness or numbness. Avoid touching your mouth or face while it is still numb to prevent accidental injury. Do not eat or drink until the numbness has completely worn off, usually within one to two hours. Keep all follow-up appointments and report any unusual symptoms promptly.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients may be more sensitive to the effects of procaine, including dizziness and cardiac effects. Use with caution and monitor closely.

🤰 Pregnancy Planning (TTC)

If you are planning pregnancy, consult your doctor before receiving this medicine. It should be used only if clearly needed.

🏥 Post-Surgery Considerations

After dental surgery, follow your dentist's instructions for care. Avoid eating until numbness subsides, and use ice packs to reduce swelling.

🦷 Dental Procedures

This medicine is used during dental procedures to provide local anesthesia and fluoride application. It is not for home use.

💚 Lifestyle Tips for Better Results

🏃
Maintain good oral hygiene by brushing twice daily and flossing.
🥗
Limit sugary snacks and drinks to prevent tooth decay.
😴
Visit your dentist regularly for check-ups and cleanings.
💧
Avoid smoking and tobacco products, which can worsen dental health.
🧘
Stay hydrated to maintain saliva production, which protects teeth.

🏋️ Exercise Considerations

Avoid strenuous exercise immediately after receiving this injection, as it may worsen dizziness. Wait until the numbness has worn off and you feel normal.

🥗 Diet Recommendations

Eat a balanced diet rich in calcium and vitamin D for strong teeth.
Avoid very hot or cold foods until numbness subsides.
Choose soft foods after dental procedures to avoid irritation.
Limit acidic and sugary foods to protect tooth enamel.

💼 Impact on Daily Work & Life

This medicine may cause dizziness and numbness, affecting your ability to drive or operate machinery. It is advisable to rest for a few hours after the injection and avoid demanding tasks until you feel fully alert.

🛑 When to Stop This Medicine

This medicine is given as a single dose by a healthcare professional. Do not self-administer. If you experience any severe side effects, inform your doctor immediately. Do not stop any prescribed treatment without consulting your doctor.

📅 Long-Term Use Effects

Long-term effects of this medicine are not well established as it is typically used for single-dose procedures. Repeated use may increase the risk of allergic reactions or local tissue damage. Monitoring for any signs of toxicity is advised if used frequently.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Topical fluoride varnish

A non-invasive alternative for caries prevention.

Evidence: Well-established
Lidocaine injection

Another local anesthetic option for dental procedures.

Evidence: Well-established

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

No known interactions with vaccines. However, inform your healthcare provider about your vaccination status before any procedure.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not freeze

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Protect from light

❌ DON'T

Do not store in direct sunlight

✈️ Traveling with This Medicine

This medicine is given by a healthcare professional and is not for self-administration. If you are traveling and need dental treatment, carry a copy of your prescription and medical records. Store the medicine in its original packaging, protected from light and extreme temperatures. Check with the airline and customs about carrying injectable medicines. It is best to have dental procedures done before travel to avoid complications.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 35-year-old woman undergoing a dental filling
She received this medicine before a cavity filling. The injection numbed the area within minutes, and the procedure was painless. She felt slight dizziness for a few minutes but it passed. She was advised not to eat for two hours and had no complications.
💡 Lesson: This medicine provides effective local anesthesia for dental procedures, but patients should be aware of temporary dizziness and avoid eating until numbness subsides.
👤 A 50-year-old man with a history of heart disease
He needed a tooth extraction and was given this medicine. His dentist monitored his heart rate and blood pressure closely. The procedure went well, but he was advised to avoid driving for the rest of the day due to mild drowsiness.
💡 Lesson: Patients with heart conditions require careful monitoring when receiving this medicine, and should arrange for transportation after the procedure.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: The numbing effect starts within 2-5 minutes after injection.

Q: How long does the numbness last?

A: The numbness typically lasts 30-60 minutes.

Q: Can I eat after the injection?

A: You should wait until the numbness has completely worn off, usually 1-2 hours, to avoid choking or biting your cheek.

Q: Is this medicine safe for children?

A: Pediatric dosing is not established. Consult a pediatrician.

Q: What are the serious side effects?

A: Serious side effects are rare but include allergic reactions, methemoglobinemia, seizures, and cardiac arrhythmias. Seek immediate medical attention if you experience difficulty breathing, bluish lips, or irregular heartbeat.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my kidney function?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?

🛑 Myths vs. Facts

  • Myth: This medicine can be used at home for toothache.
    Fact: This medicine is for professional use only and must be given by a healthcare provider.
  • Myth: It is safe to drive immediately after the injection.
    Fact: You should avoid driving for at least 2-3 hours as it may cause dizziness or numbness.
  • Myth: You can eat immediately after the injection.
    Fact: You should wait until the numbness wears off to avoid choking or biting your cheek.

📊 Comparison with Similar Medicines

[{"medicine":"This medicine","active_ingredient":"Sodium fluoride + Procaine","route":"Parenteral","main_use":"Dental anesthesia and caries prevention"},{"medicine":"Lidocaine injection","active_ingredient":"Lidocaine","route":"Parenteral","main_use":"Local anesthesia"},{"medicine":"Sodium fluoride varnish","active_ingredient":"Sodium fluoride","route":"Topical","main_use":"Caries prevention"}]

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