Acnerus I 20 Soft Gelatin Capsule (Isotretinoin 20mg): Complete Medicine Guide
When to Call Your Doctor IMMEDIATELY
- Severe headache with blurred vision or vomiting
- Yellowing of skin or eyes, dark urine, or severe fatigue
- Severe abdominal pain, nausea, or vomiting
- Rash, blisters, or peeling skin
- Mood changes, depression, or thoughts of self-harm
- Hearing loss or ringing in the ears
- Persistent diarrhea or blood in stool
- Swelling of face, lips, or throat or difficulty breathing
If experiencing severe symptoms, call emergency services immediately.
What is elvac 20mg soft gelatin capsule used for?
This medicine is a prescription retinoid used to treat severe nodular acne that has not responded to other treatments. It works by reducing oil production and preventing blocked pores. It can cause serious side effects, including birth defects, so strict pregnancy prevention is required.
- Generic Name: Isotretinoin (20mg)
- Manufacturer: Elnova Pharma
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 elvac 20mg soft gelatin capsule के बारे में (Hindi Summary)
उपयोग: यह दवा आइसोट्रेटिनोइन 20 मिलीग्राम सॉफ्ट जिलेटिन कैप्सूल के रूप में उपलब्ध है। यह मुख्य रूप से गंभीर मुँहासे (नोड्यूलर एक्ने) के इलाज के लिए इस्तेमाल की जाती है, जो अन्य दवाओं और क्रीम से ठीक नहीं हुए हों। यह त्वचा के तेल ग्रंथियों को छोटा करके तेल का उत्पादन कम करती है और बंद रोमछिद्रों को खोलने में मदद करती है। यह दवा केवल त्वचा रोग विशेषज्ञ की देखरेख में ही लेनी चाहिए। गर्भवती महिलाओं या गर्भधारण की योजना बना रही महिलाओं को यह दवा बिल्कुल नहीं लेनी चाहिए क्योंकि इससे बच्चे में गंभीर जन्म दोष हो सकते हैं।
साइड इफेक्ट्स: इस दवा के सबसे आम दुष्प्रभावों में होंठों का सूखना, त्वचा का सूखना, आँखों का सूखना और नाक का सूखना शामिल हैं। कुछ लोगों को सिरदर्द, मांसपेशियों में दर्द और धूप के प्रति संवेदनशीलता भी हो सकती है। गंभीर दुष्प्रभावों में लीवर एंजाइम का बढ़ना, रक्त में ट्राइग्लिसराइड और कोलेस्ट्रॉल का बढ़ना, मूड में बदलाव और दृष्टि में परिवर्तन शामिल हैं। अगर आपको गंभीर सिरदर्द, धुंधली दृष्टि, पेट में तेज दर्द, या त्वचा पर चकत्ते दिखें तो तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: यह दवा केवल त्वचा रोग विशेषज्ञ के परामर्श से ही लें। गर्भवती महिलाओं को यह दवा नहीं लेनी चाहिए। प्रजनन आयु की महिलाओं को इस दवा को शुरू करने से कम से कम एक महीने पहले, दवा लेने के दौरान और दवा बंद करने के एक महीने बाद तक दो विश्वसनीय गर्भनिरोधक तरीकों का इस्तेमाल करना चाहिए। इस दवा को लेते समय और बंद करने के एक महीने बाद तक रक्तदान न करें। विटामिन ए की खुराक न लें। धूप से बचाव करें और सनस्क्रीन का इस्तेमाल करें। रात में गाड़ी चलाने में परेशानी हो तो डॉक्टर को बताएं।
💊 elvac 20mg soft gelatin capsule Uses & Benefits
[{"condition":"Severe nodular acne","description":"This medicine is indicated for the treatment of severe recalcitrant nodular acne that has not responded to adequate trials of conventional therapy, including oral antibiotics and topical treatments.","evidence":"Well-established"},{"condition":"Acne conglobata","description":"A severe form of acne with deep nodules and interconnected abscesses; this medicine is used when other treatments fail.","evidence":"Well-established"},{"condition":"Acne fulminans","description":"A rare, severe form of acne with sudden onset, fever, and joint pain; this medicine may be used as part of treatment.","evidence":"Limited"},{"condition":"Gram-negative folliculitis","description":"A complication of long-term antibiotic use for acne; this medicine may be effective when other treatments are not.","evidence":"Limited"}]
Off-label uses: [{"condition":"Rosacea","description":"Sometimes prescribed off-label for severe rosacea that has not responded to other treatments.","evidence":"Limited"},{"condition":"Hidradenitis suppurativa","description":"May be used off-label in some cases, but evidence is limited and it is not a standard treatment.","evidence":"Limited"},{"condition":"Keratosis pilaris","description":"Rarely used off-label for severe keratosis pilaris, but not routinely recommended.","evidence":"Limited"},{"condition":"Cutaneous lupus erythematosus","description":"Occasionally used off-label for skin lesions of lupus, but not a first-line treatment.","evidence":"Limited"}]
Primary treatment for: Severe nodular acne
Also treats: Acne conglobata, Acne fulminans, Gram-negative folliculitis
📋 Drug Information
| Generic Name(s) | Isotretinoin (20mg) |
| Brand Name | elvac 20mg soft gelatin capsule |
| Manufacturer | Elnova Pharma |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | DERMA |
| Action Class | Retinoids- First generation |
| Route of Administration | Oral |
| Storage | Store at room temperature between 15°C and 30°C (59°F to 86°F). Protect from light and moisture. Keep in the original container. Do not refrigerate unless specified by the manufacturer. |
| Shelf Life | The shelf life is typically 24 months from the date of manufacture. Check the expiry date on the pack. Do not use after the expiry date. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine works by binding to retinoic acid receptors in the skin. This binding reduces the size and activity of sebaceous glands, decreases sebum production, and helps skin cells inside hair follicles to shed normally instead of clumping together. It also reduces the growth of Cutibacterium acnes bacteria by changing the environment inside the follicle. The result is fewer new acne lesions and less inflammation.
Mechanism Steps
💡 How to Take elvac 20mg soft gelatin capsule
Strength: This medicine is available as a soft gelatin capsule containing 20 mg of Isotretinoin.
Dosage Information
| Adult Dosage | The dose of this medicine must be individualized by a qualified clinician based on the severity of acne, response to treatment, and tolerability. A typical starting dose is 0.5 mg per kg per day, which may be increased to 1 mg per kg per day. The usual duration of treatment is 15 to 20 weeks. The dose may be adjusted based on blood test results and side effects. Do not change the dose without consulting your doctor. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatric dermatologist for individualized dosing. |
| Elderly Dosage | There is limited information on the use of this medicine in elderly patients. It should be used with caution and the dose should be individualized by a qualified clinician based on renal and hepatic function and other medicines being taken. |
| Renal Impairment | The effect of kidney impairment on this medicine is not well established. Use with caution in patients with kidney disease. The dose may need to be adjusted by a qualified clinician. |
| Hepatic Impairment | This medicine is contraindicated in patients with severe liver disease. In patients with mild to moderate liver impairment, the dose should be individualized by a qualified clinician and liver function should be monitored closely. |
| Maximum Daily Dose | The maximum recommended daily dose is 1 mg per kg per day, but the exact maximum must be determined by a qualified clinician based on individual factors. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of elvac 20mg soft gelatin capsule
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Tetracycline antibiotics | Major | |
| Vitamin A supplements | Major | |
| Other retinoids | Major | |
| Low-dose progestin-only contraceptives | Major | |
| Phenytoin | Moderate | |
| Carbamazepine | Moderate | |
| St. John's wort | Moderate | |
| Alcohol | Moderate | |
| Corticosteroids | Minor | |
| Grapefruit juice | Minor |
🚨 Major Interactions
- Tetracycline antibiotics (e.g., doxycycline, minocycline)
- Vitamin A supplements
- Other retinoids (e.g., acitretin, tretinoin)
- Hormonal contraceptives (low-dose progestin-only pills)
⚡ Moderate Interactions
- Phenytoin
- Carbamazepine
- St. John's wort
🍷 Alcohol Interaction
Alcohol may increase the risk of liver problems and raise triglyceride levels when taken with this medicine. It is best to avoid alcohol or limit intake while taking this medicine. Consult your doctor for personalized advice.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Pregnancy or planning to become pregnant","Breastfeeding","Known hypersensitivity to isotretinoin or any component of the formulation","Severe liver disease","Very high blood triglyceride levels","Use of tetracycline antibiotics","Use of vitamin A supplements"]
⚠️ Warnings & Precautions
["This medicine can cause severe birth defects. Women must use two forms of contraception and have regular pregnancy tests.","Do not donate blood while taking this medicine and for one month after stopping.","Avoid vitamin A supplements and multivitamins containing vitamin A.","This medicine may cause dry eyes and decreased night vision. Use caution when driving at night.","This medicine may cause mood changes or depression. Report any changes to your doctor immediately.","This medicine can increase blood triglycerides and cholesterol. Follow a low-fat diet if advised.","This medicine can increase liver enzymes. Avoid alcohol and other liver-toxic medicines.","This medicine may cause increased pressure inside the skull. Report severe headache, blurred vision, or vomiting.","This medicine may cause severe skin reactions. Report rash, blisters, or peeling skin.","This medicine may cause hearing changes. Report any hearing loss.","This medicine may cause inflammatory bowel disease. Report persistent diarrhea or abdominal pain.","This medicine may interact with other medicines. Tell your doctor about all medicines you take."]
🤱 Lactation Safety
This medicine is present in breast milk and may harm a nursing infant. Breastfeeding is not recommended while taking this medicine. Consult your doctor for alternative feeding options.
💊 Overdose Management
Overdose of this medicine may cause severe headache, nausea, vomiting, and other symptoms. If you suspect an overdose, seek immediate medical attention or contact a poison control center. Treatment is supportive and symptomatic. There is no specific antidote.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for a missed one.
Additional Safety Advice
This medicine must only be taken under the supervision of a dermatologist. Women of childbearing age must use two reliable forms of contraception for at least one month before starting, during treatment, and for one month after the last dose. A negative pregnancy test is required before starting and at regular intervals during treatment. Do not donate blood while taking this medicine and for one month after stopping, because the medicine can harm a pregnant recipient. Avoid vitamin A supplements and multivitamins containing vitamin A, as they can increase side effects. Protect your skin from the sun with sunscreen and protective clothing. Do not drive at night if you notice reduced night vision. Tell your doctor about all other medicines you take, especially tetracycline antibiotics, because they can increase the risk of increased pressure inside the skull. Do not start or stop this medicine without your doctor's advice.
👴 Special Considerations for Elderly
💡 For Patients Above 65
There is limited information on the use of this medicine in elderly patients. It should be used with caution, and the dose should be individualized by a qualified clinician based on renal and hepatic function and other medicines being taken. Elderly patients may be more susceptible to side effects.
🤰 Pregnancy Planning (TTC)
This medicine causes severe birth defects. Women who are planning to become pregnant must not take this medicine. If you are taking this medicine and wish to become pregnant, stop the medicine and consult your doctor. You must wait at least one month after stopping the medicine before attempting to conceive. Use two forms of contraception during treatment and for one month after stopping.
🏥 Post-Surgery Considerations
This medicine may affect wound healing and increase the risk of bleeding. Inform your surgeon that you are taking this medicine before any surgery. Your doctor may advise you to stop the medicine temporarily before surgery. Do not stop without consulting your doctor.
🦷 Dental Procedures
This medicine can cause dry mouth and increase the risk of dental problems. Inform your dentist that you are taking this medicine before any dental procedure. Maintain good oral hygiene and stay hydrated. Your dentist may recommend additional preventive care.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
This medicine can cause muscle and joint pain. Avoid strenuous exercise if you experience pain. Mild to moderate exercise is generally safe. Stay hydrated. Consult your doctor if pain persists or worsens.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause dry eyes and decreased night vision, which can affect driving, especially at night. Use caution when driving or operating machinery until you know how this medicine affects you. It may also cause mood changes, which can impact work and social life. Report any such changes to your doctor. Take regular breaks if you work on a computer to manage dry eyes.
🛑 When to Stop This Medicine
Do not stop this medicine without consulting your doctor. Stopping early may lead to relapse of acne. Your doctor will decide when to stop based on your response and completion of the course. If you experience serious side effects, contact your doctor immediately; they may advise you to stop. Always follow your doctor's instructions.
📅 Long-Term Use Effects
Long-term use of this medicine is not recommended beyond the prescribed course. Prolonged use may increase the risk of liver problems, high blood lipids, and bone density loss. Regular monitoring of liver function, lipid profile, and pregnancy status is required. Some people may experience persistent dry eyes or skin sensitivity after stopping. Acne may relapse after treatment, requiring further evaluation. Always follow your doctor's guidance on duration and monitoring.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Can be used for mild to moderate acne but are less effective for severe nodular acne.
Evidence: Well-establishedMay be used for moderate to severe acne but are not as effective as this medicine for nodular acne.
Evidence: Well-establishedFor women with hormonal acne, but not a substitute for this medicine in severe cases.
Evidence: Well-establishedCan help with acne scars but does not treat active severe nodular acne.
Evidence: Limited💉 Vaccination Considerations
💉 If You're Getting Vaccinated
There are no known interactions between this medicine and vaccines. However, consult your doctor before receiving any vaccine while taking this medicine.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✅ DO
Keep out of reach of children
❌ DON'T
Do not use after expiry date
✈️ Traveling with This Medicine
When traveling, carry this medicine in its original packaging with the prescription label. Bring a copy of your prescription and a letter from your doctor explaining the medical need, especially for international travel. Store it at room temperature and protect it from extreme heat or cold. If crossing time zones, continue taking your doses at the same intervals as prescribed; do not double up. Keep enough supply for your entire trip. Women should continue pregnancy prevention and carry contraception. Do not donate blood during travel.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: You may notice some improvement after 2 to 4 weeks, but significant improvement usually takes 1 to 2 months. The full effect may take 4 to 6 months.
A: Yes, take it with food, preferably a high-fat meal, to improve absorption.
A: Serious side effects include birth defects, liver problems, increased blood lipids, mood changes, increased pressure inside the skull, and pancreatitis. Report any unusual symptoms to your doctor.
A: It is best to avoid alcohol because it can increase the risk of liver problems and raise triglyceride levels.
A: Yes, women of childbearing age must use two reliable forms of contraception before, during, and for one month after treatment.
A: No, you must not donate blood while taking this medicine and for one month after stopping.
A: If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double dose.
A: Yes, this medicine can cause mood changes or depression. Report any changes in mood or thoughts of self-harm to your doctor immediately.
A: Treatment usually lasts 15 to 20 weeks, but your doctor will determine the exact duration based on your response.
A: Do not use other acne treatments without consulting your doctor, as some may interact or increase side effects.
🤔 Common Patient Concerns
🔄 Substitutes for elvac 20mg soft gelatin capsule
View AllAlternative brands with exact same active ingredient:
-
actinin o 20mg soft gelatin capsuleZeelab Pharmacy Pvt Ltd ₹36.00 72.3% CHEAPER
-
davaindia isotretinoin 20mg capsuleDavaindia Generic Pharmacy ₹42.00 67.7% CHEAPER
-
aczit 20mg capsuleCanixa Life Sciences Pvt ₹108.17 16.8% CHEAPER
-
stayhappi isotretinoin 20mg capsuleSarvagunaushdhi Pvt Ltd ₹108.89 16.2% CHEAPER
-
face 20mg capsuleBonsai Pharma ₹112.50 13.5% CHEAPER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine is a quick fix for any acne.
Fact: This medicine is only for severe nodular acne that has not responded to other treatments. It is not for mild or moderate acne. - Myth: You can stop this medicine as soon as your acne clears.
Fact: You must complete the full course as prescribed by your doctor to prevent relapse and ensure the best results. - Myth: This medicine is safe to take during pregnancy.
Fact: This medicine causes severe birth defects and must never be taken during pregnancy. Strict pregnancy prevention is required. - Myth: You can donate blood while taking this medicine.
Fact: You must not donate blood while taking this medicine and for one month after stopping, because it can harm a pregnant recipient. - Myth: This medicine only affects the skin.
Fact: This medicine can affect the liver, blood lipids, eyes, and mood. Regular monitoring is required.
🔄 Alternative Options
Generic Alternatives
- Isotretinoin 20 mg soft gelatin capsule
Brand Alternatives
- Accufine 20
- Sotret 20
- Tretiva 20
- Isotroin 20