Eclarin Dry Syrup: Complete Guide to Uses, Dosage, and Safety
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Severe, watery, or bloody diarrhea that does not improve
- Yellowing of the skin or eyes (jaundice)
- Severe abdominal pain that radiates to the back
- Swelling of the face, lips, tongue, or throat, or difficulty breathing
- Palpitations, fainting, or seizures
- Unusual bruising or bleeding
- Signs of a severe skin reaction such as painful rash, blisters, or peeling skin
If experiencing severe symptoms, call emergency services immediately.
What is eclarin dry syrup used for?
This medicine is a macrolide antibiotic used to treat bacterial infections such as pneumonia, bronchitis, sinusitis, and skin infections. It works by stopping bacteria from making proteins they need to survive. It is available as a dry syrup that must be mixed with water before use. Always complete the full course as prescribed.
- Generic Name: Clarithromycin (125mg/5ml)
- Manufacturer: Esquire Drug House
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 eclarin dry syrup के बारे में (Hindi Summary)
उपयोग: यह दवा क्लैरिथ्रोमाइसिन नामक एंटीबायोटिक है, जिसका उपयोग बैक्टीरियल संक्रमणों के इलाज के लिए किया जाता है। यह मुख्य रूप से श्वसन तंत्र के संक्रमण जैसे निमोनिया, ब्रोंकाइटिस, साइनसाइटिस, कान के संक्रमण, गले के संक्रमण और त्वचा के संक्रमण के लिए दी जाती है। यह दवा बैक्टीरिया के प्रोटीन संश्लेषण को रोककर उन्हें मारती है। यह सूखे सिरप के रूप में आती है जिसे पानी में मिलाकर तैयार किया जाता है। इसे डॉक्टर के निर्देशानुसार पूरा कोर्स करना चाहिए, भले ही लक्षण ठीक हो जाएं।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में मतली, दस्त, पेट दर्द, स्वाद में बदलाव और सिरदर्द शामिल हैं। ये आमतौर पर हल्के होते हैं और इलाज जारी रखने पर ठीक हो जाते हैं। कभी-कभी गंभीर दुष्प्रभाव जैसे गंभीर दस्त, लीवर की समस्या, या एलर्जी प्रतिक्रिया हो सकती है। यदि आपको गंभीर या असामान्य लक्षण दिखें, तो तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। पूरा कोर्स पूरा करें, चाहे आप बेहतर महसूस करें। दवा को अच्छी तरह हिलाकर लें और सही मापने वाले चम्मच या कप का उपयोग करें। इसे भोजन के साथ या बिना भोजन के लिया जा सकता है, लेकिन भोजन के साथ लेने से पेट की परेशानी कम हो सकती है। शराब का सेवन न करें। अपने डॉक्टर को अन्य सभी दवाओं के बारे में बताएं जो आप ले रहे हैं। गुर्दे या लीवर की बीमारी हो तो डॉक्टर को बताएं।
💊 eclarin dry syrup Uses & Benefits
- [{"condition":"Community-acquired pneumonia","description":"Used to treat mild to moderate community-acquired pneumonia caused by susceptible bacteria such as Streptococcus pneumoniae, Haemophilus influenzae, and atypical pathogens like Mycoplasma pneumoniae.","evidence":"Well-established"},{"condition":"Acute bacterial exacerbation of chronic bronchitis","description":"Helps clear bacterial infections that worsen chronic bronchitis, reducing symptoms and preventing complications.","evidence":"Well-established"},{"condition":"Acute bacterial sinusitis","description":"Effective against common sinus infection pathogens when antibiotic therapy is deemed necessary.","evidence":"Well-established"},{"condition":"Acute otitis media","description":"Used in children and adults for middle ear infections caused by susceptible bacteria, especially when penicillin cannot be used.","evidence":"Well-established"},{"condition":"Pharyngitis and tonsillitis","description":"Prescribed for streptococcal throat infections in patients who are allergic to penicillin.","evidence":"Well-established"},{"condition":"Skin and soft tissue infections","description":"Treats uncomplicated skin infections such as cellulitis, impetigo, and erysipelas caused by susceptible organisms.","evidence":"Well-established"},{"condition":"Helicobacter pylori eradication","description":"Used as part of combination therapy with a proton pump inhibitor and amoxicillin or metronidazole to eradicate H.
- pylori in peptic ulcer disease.","evidence":"Well-established"},{"condition":"Mycobacterium avium complex (MAC) infection","description":"Used for prevention and treatment of disseminated MAC infection in patients with advanced HIV/AIDS.","evidence":"Well-established"}]
Off-label uses: [{"condition":"Pertussis (whooping cough)","description":"Sometimes used to reduce transmission of Bordetella pertussis, although azithromycin is generally preferred.","evidence":"Limited"},{"condition":"Lyme disease","description":"May be used as an alternative in patients who cannot take doxycycline, but evidence is limited compared to standard therapy.","evidence":"Limited"},{"condition":"Mycoplasma genitalium infection","description":"Occasionally used when other options are not suitable, but resistance is a concern.","evidence":"Limited"}]
Primary treatment for: Bacterial infections
Also treats: Community-acquired pneumonia, Acute bacterial exacerbation of chronic bronchitis, Acute bacterial sinusitis, Acute otitis media, Pharyngitis/tonsillitis, Skin and soft tissue infections, Helicobacter pylori infection, Mycobacterium avium complex infection
📋 Drug Information
| Generic Name(s) | Clarithromycin (125mg/5ml) |
| Brand Name | eclarin dry syrup |
| Manufacturer | Esquire Drug House |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | ANTI INFECTIVES |
| Action Class | Macrolides |
| Route of Administration | Oral |
| Storage | Store the dry powder at room temperature (15-30°C) in a tightly closed container, protected from light and moisture. After reconstitution, store the suspension at room temperature or in the refrigerator (2-8°C) as directed on the label. Do not freeze. Discard any unused suspension after 14 days (or as specified by the manufacturer). Keep out of reach of children. |
| Shelf Life | The shelf life of the dry powder is typically 24 months from the date of manufacture. After reconstitution, the suspension should be used within 14 days if stored at room temperature or in the refrigerator. Refer to the product label for exact expiration dates. |
| WHO Guideline | The World Health Organization (WHO) includes clarithromycin in its Model List of Essential Medicines for the treatment of certain bacterial infections, including community-acquired pneumonia and Helicobacter pylori eradication. However, specific recommendations depend on local resistance patterns and national guidelines. |
| ICMR Guideline | The Indian Council of Medical Research (ICMR) has published treatment guidelines for antimicrobial use. Clarithromycin is recommended for specific indications such as community-acquired pneumonia, especially in patients with penicillin allergy, and as part of H. pylori eradication regimens. Always follow the latest ICMR guidelines and local antibiogram data. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine belongs to the macrolide class of antibiotics. It works by binding reversibly to the 50S subunit of the bacterial ribosome, specifically to the 23S ribosomal RNA. This binding blocks the translocation step of protein synthesis, preventing the growing peptide chain from moving from the A site to the P site. As a result, bacteria cannot produce essential proteins and their growth is halted. This medicine is primarily bacteriostatic, meaning it stops bacteria from multiplying, but it can be bactericidal at higher concentrations against certain highly susceptible organisms. It is effective against a broad range of gram-positive and atypical bacteria, including Streptococcus species, Staphylococcus species, Haemophilus influenzae, Mycoplasma pneumoniae, Chlamydia trachomatis, and Legionella pneumophila. It also has activity against Mycobacterium avium complex and some Helicobacter pylori strains.
Mechanism Steps
💡 How to Take eclarin dry syrup
Strength: Dry syrup for oral suspension, containing clarithromycin 125 mg per 5 mL after reconstitution. The bottle typically contains enough powder to make 50 mL or 100 mL of suspension, providing 1250 mg or 2500 mg of clarithromycin respectively.
Dosage Information
| Adult Dosage | The usual adult dose of this medicine is 250 mg to 500 mg every 12 hours, depending on the type and severity of the infection. For more severe infections, doses up to 500 mg every 12 hours may be used. The duration of therapy typically ranges from 7 to 14 days, but may be longer for certain infections such as Mycobacterium avium complex. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Always follow your doctor's prescription exactly. |
| Pediatric Dosage | Pediatric dosing of this medicine is based on body weight and is individualized by a pediatrician. The usual dose is 7.5 mg/kg every 12 hours for most infections, but dosing may vary depending on the specific infection and the child's renal function. This dry syrup formulation is intended for children who can take oral liquids. Do not attempt to calculate the dose yourself; consult a pediatrician for accurate dosing. |
| Elderly Dosage | Elderly patients may be more sensitive to the side effects of this medicine, especially QT prolongation and renal impairment. Dose adjustment may be necessary based on renal function. Elderly patients should be monitored closely for signs of toxicity. The usual adult dose may be used if renal function is normal, but caution is advised. |
| Renal Impairment | In patients with severe renal impairment (creatinine clearance <30 mL/min), the dose of this medicine should be reduced by half. For example, if the usual dose is 500 mg every 12 hours, it should be reduced to 250 mg every 12 hours. In patients with moderate renal impairment (creatinine clearance 30-60 mL/min), no dose adjustment is usually necessary, but monitoring is advised. Always consult a clinician for dose adjustment. |
| Hepatic Impairment | No specific dose adjustment is provided for patients with hepatic impairment, but caution is advised. This medicine is metabolized in the liver, and patients with severe liver disease may have increased drug levels. Monitor liver function tests and clinical response. Dose reduction may be considered based on clinical judgment. |
| Maximum Daily Dose | The maximum recommended daily dose of this medicine for adults is 1000 mg (e.g., 500 mg every 12 hours). Higher doses may be used in certain serious infections under close medical supervision, but should not exceed 1000 mg per day without specialist guidance. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of eclarin dry syrup
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | |
| Simvastatin | Major | |
| Ergotamine | Major | |
| Cisapride | Major | |
| Pimozide | Major | |
| Digoxin | Major | |
| Carbamazepine | Moderate | |
| Cyclosporine | Moderate | |
| Theophylline | Moderate | |
| Oral hypoglycemics | Moderate |
🚨 Major Interactions
- Ergotamine and dihydroergotamine
- Cisapride
- Pimozide
- Terfenadine and astemizole
- Simvastatin and lovastatin
- Warfarin
- Colchicine
- Digoxin
⚡ Moderate Interactions
- Carbamazepine
- Cyclosporine
- Tacrolimus
- Theophylline
- Oral hypoglycemic agents (e.g., glipizide, glyburide)
- Fluconazole
- Ritonavir
- Verapamil
🍷 Alcohol Interaction
It is advisable to avoid alcohol while taking this medicine. Alcohol can increase the risk of stomach irritation, nausea, and dizziness. It may also put extra strain on the liver, which is already involved in metabolizing this medicine. If you drink alcohol regularly, discuss it with your doctor before starting this medicine.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Known hypersensitivity to clarithromycin or other macrolide antibiotics","Concomitant use with ergotamine or dihydroergotamine","Concomitant use with cisapride","Concomitant use with pimozide","Concomitant use with terfenadine or astemizole","History of QT prolongation or ventricular arrhythmias","Severe hepatic impairment","Hypokalemia or hypomagnesemia (uncorrected)"]
⚠️ Warnings & Precautions
["Do not use this medicine for viral infections such as the common cold or flu; it is ineffective and may promote antibiotic resistance.","Use with caution in patients with liver disease; monitor liver function.","Use with caution in patients with kidney disease; dose adjustment may be needed.","May cause dizziness; avoid driving or operating machinery until you know how it affects you.","Avoid alcohol while taking this medicine.","May interact with many other medicines; always inform your doctor about all medications you are taking.","Prolonged use may lead to overgrowth of non-susceptible bacteria or fungi; monitor for superinfections.","Do not share this medicine with others, even if they have similar symptoms.","Complete the full course as prescribed, even if you feel better, to prevent recurrence and resistance."]
🤱 Lactation Safety
This medicine is excreted in human breast milk. Because of the potential for serious adverse reactions in nursing infants, a decision should be made whether to discontinue nursing or to discontinue the drug, taking into account the importance of the drug to the mother. Caution is advised when used during breastfeeding.
💊 Overdose Management
Overdose of this medicine may cause severe nausea, vomiting, diarrhea, and abdominal pain. In severe cases, it may lead to electrolyte imbalances and QT prolongation. There is no specific antidote. Treatment is supportive and symptomatic. If overdose is suspected, contact a poison control center or emergency room immediately. Gastric lavage may be considered if the overdose is recent and the patient is seen within a short time. Monitor vital signs, electrolytes, and ECG.
⏰ Missed Dose
If you miss a dose of this medicine, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one. If you are unsure, consult your doctor or pharmacist.
Additional Safety Advice
Take this medicine exactly as prescribed by your doctor. Do not skip doses or stop treatment early, even if you feel better, because doing so can allow the infection to return and may lead to antibiotic resistance. Shake the bottle well before each dose to ensure the medicine is evenly mixed. Use a proper measuring device, such as the spoon or cup provided, to measure each dose accurately. This medicine can be taken with or without food, but taking it with food may help reduce stomach upset. Avoid alcohol while taking this medicine, as it can worsen dizziness and stomach irritation. Tell your doctor about all other medicines you are taking, especially blood thinners, statins, diabetes medicines, and migraine medicines, because this medicine can interact with many drugs. If you have kidney or liver problems, your doctor may need to adjust your dose or monitor you more closely. Do not share this medicine with anyone else, even if they have similar symptoms. Store the reconstituted suspension as directed on the label, usually at room temperature, and discard any unused portion after the specified number of days.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients may be more susceptible to the side effects of this medicine, particularly QT prolongation, renal impairment, and liver toxicity. Dose adjustment may be necessary based on kidney function. Regular monitoring of renal and hepatic function is advised. Elderly patients should also be cautious about drug interactions, as they often take multiple medications.
🤰 Pregnancy Planning (TTC)
If you are planning to become pregnant, discuss with your doctor before taking this medicine. This medicine is Pregnancy Category C and should only be used if clearly needed. If you become pregnant while taking this medicine, inform your doctor immediately.
🏥 Post-Surgery Considerations
If you are scheduled for surgery, inform your surgeon that you are taking this medicine. It may interact with anesthetics or other medications used during surgery. Your doctor may advise you to stop the medicine temporarily before surgery.
🦷 Dental Procedures
Inform your dentist that you are taking this medicine before any dental procedure. This medicine may interact with certain antibiotics or anesthetics used in dentistry. It is generally safe to continue, but your dentist may take precautions.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
While taking this medicine, you may feel tired or dizzy. Avoid strenuous exercise until you feel better. Light activities like walking are fine if you feel up to it. If you experience dizziness or palpitations, stop exercising and consult your doctor.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause dizziness or tiredness in some people. Avoid driving or operating heavy machinery until you know how it affects you. If your work involves operating machinery or driving, inform your employer and take necessary precautions. Most people can continue their usual activities, but rest is important for recovery.
🛑 When to Stop This Medicine
Do not stop taking this medicine without consulting your doctor, even if you feel better. Stopping early can lead to recurrence of infection and antibiotic resistance. If you experience severe side effects, contact your doctor immediately; they may advise you to stop or switch to a different antibiotic.
📅 Long-Term Use Effects
Long-term use of this medicine is not usually recommended unless for specific chronic infections like Mycobacterium avium complex. Prolonged use can lead to overgrowth of non-susceptible bacteria or fungi, and may increase the risk of antibiotic resistance. Regular monitoring of liver and kidney function may be required during prolonged therapy. If you need to take this medicine for more than a few weeks, your doctor will monitor you closely.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Another macrolide antibiotic with a longer half-life and simpler dosing regimen.
Evidence: Well-establishedA penicillin antibiotic that may be used if the infection is susceptible and the patient is not allergic.
Evidence: Well-establishedFor viral infections, rest, fluids, and over-the-counter remedies are appropriate; antibiotics are not effective.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
There are no known interactions between this medicine and vaccines. However, if you are scheduled to receive a live bacterial vaccine (e.g., typhoid vaccine), antibiotics may reduce its effectiveness. Consult your doctor for specific advice.
📦 Storage Guide
✅ DO
Store dry powder at room temperature (15-30°C)
❌ DON'T
Do not refrigerate the dry powder
✅ DO
After reconstitution, store suspension in refrigerator (2-8°C) if directed
❌ DON'T
Do not freeze the suspension
✅ DO
Keep in original container with cap tightly closed
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Discard unused suspension after 14 days
❌ DON'T
Do not use beyond the expiration date
✈️ Traveling with This Medicine
When traveling with this medicine, carry it in its original packaging with the prescription label intact. Bring a copy of your prescription or a letter from your doctor, especially for international travel. If you need to reconstitute the syrup during travel, use clean bottled water and follow the instructions carefully. Store the reconstituted suspension as directed, and keep it away from extreme heat or direct sunlight. If crossing time zones, adjust your dosing schedule gradually to maintain even intervals between doses. Check customs regulations for carrying prescription medicines into your destination country.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: This medicine starts working within a few hours, but you may not notice improvement in symptoms for 24 to 48 hours. It is important to complete the full course as prescribed.
A: Yes, you can take this medicine with or without food. Taking it with food may help reduce stomach upset.
A: If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double dose.
A: Yes, this medicine is often prescribed for children, but the dose is based on body weight and must be determined by a pediatrician.
A: No, you must complete the full course as prescribed, even if you feel better, to prevent the infection from returning and to avoid antibiotic resistance.
🤔 Common Patient Concerns
🔄 Substitutes for eclarin dry syrup
View AllAlternative brands with exact same active ingredient:
-
claridac 125mg/5ml oral suspensionIkon Remedies Pvt Ltd ₹115.00 259.4% COSTLIER
-
clarithral 125 oral suspensionInnovative Pharmaceuticals ₹115.00 259.4% COSTLIER
-
euclar dry syrupNovogen Captab ₹117.19 266.2% COSTLIER
-
monoclar dry syrupCaptab Biotec ₹117.19 266.2% COSTLIER
-
claron oral suspensionAgex Laboratories Pvt Ltd ₹118.13 269.2% COSTLIER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: Antibiotics can cure the common cold.
Fact: The common cold is caused by viruses, and this medicine is only effective against bacteria. Using it for viral infections is ineffective and can lead to antibiotic resistance. - Myth: You can stop taking this medicine as soon as you feel better.
Fact: You must complete the full course as prescribed, even if symptoms improve, to ensure all bacteria are killed and prevent recurrence and resistance. - Myth: This medicine is safe to take during pregnancy without any risk.
Fact: This medicine is Pregnancy Category C and should only be used during pregnancy if the potential benefit justifies the potential risk to the fetus. Consult your doctor. - Myth: This medicine can be taken with any other medication without concern.
Fact: This medicine interacts with many drugs, including warfarin, statins, and certain migraine medicines. Always inform your doctor about all medicines you are taking.
🔄 Alternative Options
Generic Alternatives
- Clarithromycin oral suspension
Brand Alternatives
- Eclarin Dry Syrup