dxl 100 capsule - Doxycycline (100mg) + Lactobacillus (5Million spores) medicine

Dxl 100 Capsule: Comprehensive Medicine Guide

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🏭 Abrik Remedies Private Limited 📦 Varies by brand 💊 Allopathy 📅 Updated: Nov 3, 2026
⚠️ Hepatotoxicity Risk 🤰 Pregnancy Category Doxycycline is not recommended during pregnancy because it can harm the developing fetus, including causing permanent discoloration of the teeth if used during the last half of pregnancy. It should only be used if the potential benefit justifies the potential risk, as determined by a doctor. 📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Well-established for indicated uses.
Reviewed by
SaathiMed Expert Panel | Nov 03, 2026
🩺
Medically Fact-Checked & Clinically Verified by SaathiMed Clinical Review Board
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026

When to Call Your Doctor IMMEDIATELY

  • Severe allergic reaction: swelling of face, lips, tongue, or throat, difficulty breathing.
  • Signs of liver problems: yellowing of skin or eyes, dark urine, severe abdominal pain.
  • Severe skin reaction: painful rash with blisters, peeling skin, or sores in the mouth or eyes.
  • Intracranial hypertension: severe headaches, vision changes, or ringing in the ears.
  • Severe diarrhea that does not improve or is accompanied by blood or mucus.
  • Chest pain or difficulty swallowing.
  • Unusual bruising or bleeding.

If experiencing severe symptoms, call emergency services immediately.

What is dxl 100 capsule used for?

This medicine is a combination of doxycycline, an antibiotic, and Lactobacillus, a probiotic. It is used to treat various bacterial infections and helps maintain gut health during antibiotic therapy.

  • Generic Name: Doxycycline + Lactobacillus
  • Manufacturer: Abrik Remedies Private Limited
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 dxl 100 capsule के बारे में (Hindi Summary)

उपयोग: यह दवा डॉक्सीसाइक्लिन और लैक्टोबैसिलस का संयोजन है। इसका उपयोग विभिन्न जीवाणु संक्रमणों जैसे श्वसन तंत्र संक्रमण, त्वचा संक्रमण, मूत्र मार्ग संक्रमण, क्लैमाइडिया, और मुँहासे के इलाज के लिए किया जाता है। यह मलेरिया की रोकथाम में भी प्रयोग किया जाता है। लैक्टोबैसिलस आंतों में अच्छे बैक्टीरिया को बनाए रखने में मदद करता है, जो एंटीबायोटिक के कारण प्रभावित हो सकते हैं।

साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में मतली, उल्टी, दस्त, पेट दर्द, और भूख में कमी शामिल हैं। कुछ लोगों को धूप के प्रति संवेदनशीलता हो सकती है। दुर्लभ मामलों में गंभीर एलर्जी, यकृत की समस्या, या गंभीर त्वचा प्रतिक्रिया हो सकती है। यदि आपको कोई असामान्य लक्षण दिखे तो तुरंत डॉक्टर से संपर्क करें।

सुरक्षा सलाह: इस दवा को एक गिलास पानी के साथ लें। इसे लेने के बाद कम से कम 30 मिनट तक लेटें नहीं। धूप से बचें और सनस्क्रीन का प्रयोग करें। एंटासिड, आयरन, या कैल्शियम सप्लीमेंट को इस दवा से 2 घंटे पहले या बाद में न लें। डॉक्टर द्वारा बताई गई पूरी अवधि तक दवा लें, भले ही आप बेहतर महसूस करें। गर्भवती या स्तनपान कराने वाली महिलाएं बिना डॉक्टर की सलाह के इसका सेवन न करें।

💡 Did You Know? The first generic medicine was introduced in India in 1970 after the Patents Act was amended.

💊 dxl 100 capsule Uses & Benefits

[{"condition":"Respiratory tract infections","description":"Used to treat certain bacterial infections of the respiratory tract, such as acute exacerbations of chronic bronchitis and community-acquired pneumonia caused by susceptible organisms.","evidence":"Well-established"},{"condition":"Skin and soft tissue infections","description":"Effective against many bacteria that cause skin infections, including cellulitis and abscesses, when the causative organism is susceptible.","evidence":"Well-established"},{"condition":"Urinary tract infections","description":"Prescribed for some urinary tract infections, particularly those caused by susceptible bacteria, when other options are not suitable.","evidence":"Established"},{"condition":"Sexually transmitted infections","description":"Used in the treatment of chlamydia, gonorrhea (in combination with other antibiotics), and syphilis in patients allergic to penicillin.","evidence":"Well-established"},{"condition":"Acne vulgaris","description":"Used for moderate to severe acne to reduce inflammation and bacterial growth on the skin.","evidence":"Well-established"},{"condition":"Malaria prevention","description":"Used for prevention of malaria in travelers to certain regions, as recommended by health authorities.","evidence":"Well-established"}]

Off-label uses: [{"condition":"Rosacea","description":"Sometimes prescribed off-label for rosacea to reduce papules and pustules.","evidence":"Limited"},{"condition":"Lyme disease","description":"Used off-label for early Lyme disease in some settings, though other antibiotics are often preferred.","evidence":"Limited"}]

Primary treatment for: Bacterial infections

Also treats: Acne, Malaria prevention, Chlamydia, Lyme disease

📋 Drug Information

Generic Name(s)Doxycycline + Lactobacillus
Brand NameAdoxy LB Capsule
ManufacturerAbrik Remedies Private Limited
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassANTI INFECTIVES
Action ClassTetracycline Antibiotic + Probiotic
Route of AdministrationOral
StorageStore at room temperature between 15°C and 30°C (59°F to 86°F). Protect from light and moisture. Keep in the original container.
Shelf Life24 months from the date of manufacture.
WHO GuidelineDoxycycline is included in the WHO Model List of Essential Medicines for the treatment of several bacterial infections, including cholera, chlamydia, and malaria. It is also recommended for malaria prophylaxis in certain regions.
ICMR GuidelineThe Indian Council of Medical Research (ICMR) recommends doxycycline for the treatment of scrub typhus, community-acquired pneumonia, and other susceptible infections. It is also used for malaria prophylaxis as per national guidelines.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Take this medicine with a full glass of water and remain upright for at least 30 minutes to prevent esophageal irritation.
2
Avoid taking antacids, iron supplements, or calcium supplements within 2 hours of this medicine, as they can reduce its absorption.
3
Use sunscreen and protective clothing while taking this medicine, as it can make your skin more sensitive to sunlight.
4
Complete the full course of antibiotics as prescribed, even if you start feeling better after a few days.
5
If you experience severe diarrhea, abdominal pain, or signs of an allergic reaction, contact your doctor immediately.
6
Inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding before taking this medicine.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅
Bacterial infection symptoms (fever, pain, swelling)
This medicine is commonly prescribed for these.
Likely Use
✅
Acne
This medicine is used for moderate to severe acne.
Likely Use
❌
Viral infection (cold, flu)
This medicine is not effective against viral infections.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionDoxycycline is well absorbed from the gastrointestinal tract after oral administration, with absorption not significantly affected by food, although food may reduce stomach upset. The presence of divalent and trivalent cations such as calcium, magnesium, iron, and aluminum can reduce absorption.
DistributionDoxycycline is highly lipophilic and distributes widely into body tissues and fluids, including the liver, kidneys, lungs, and bile. It also crosses the placenta and is excreted in breast milk.
Protein BindingDoxycycline is approximately 90% bound to plasma proteins.
MetabolismDoxycycline is not extensively metabolized in the liver; it is primarily excreted unchanged.
Half-LifeThe elimination half-life of doxycycline is approximately 18 to 22 hours in patients with normal renal function.
ExcretionDoxycycline is excreted mainly in the feces and urine. It is partially inactivated in the intestine by chelation with calcium.
BioavailabilityThe oral bioavailability of doxycycline is approximately 90% to 100% in fasting individuals.
Onset of ActionThe onset of action for doxycycline is typically within 1 to 2 hours after oral administration, but clinical improvement may take 24 to 48 hours.
Peak Plasma TimePeak plasma concentrations are reached approximately 2 to 3 hours after oral administration.
Duration of ActionThe duration of action is typically 24 hours, allowing for once or twice daily dosing.

How It Works

Doxycycline is a broad-spectrum tetracycline antibiotic that works by binding to the 30S ribosomal subunit of susceptible bacteria. This binding prevents the attachment of aminoacyl-tRNA to the mRNA-ribosome complex, thereby inhibiting protein synthesis and stopping bacterial growth. Lactobacillus is a probiotic that helps restore and maintain the natural balance of beneficial bacteria in the gastrointestinal tract, which can be disrupted by antibiotic therapy.

Mechanism Steps

1
Entry into bacterial cell: Doxycycline enters the bacterial cell through porin channels and energy-dependent transport mechanisms.
2
Binding to ribosome: Once inside, doxycycline binds reversibly to the 30S ribosomal subunit.
3
Inhibition of protein synthesis: This binding blocks the addition of new amino acids to the growing peptide chain, preventing bacterial protein synthesis.
4
Bacteriostatic effect: As a result, bacteria cannot grow or multiply, allowing the body's immune system to eliminate them.
5
Probiotic support: Lactobacillus spores survive passage through the stomach and colonize the gut, helping to restore beneficial bacteria that may be killed by the antibiotic.

💡 How to Take dxl 100 capsule

Strength: Capsule containing Doxycycline 100 mg and Lactobacillus 5 million spores.

1Take this medicine exactly as prescribed by your doctor.
2Swallow the capsule whole with a full glass of water.
3Take with food or milk to reduce stomach upset.
4Do not lie down for at least 30 minutes after taking.
5Avoid taking antacids, iron, or calcium supplements within 2 hours.
6Complete the full course of treatment.

Dosage Information

Adult DosageThe usual adult dose of this medicine is one capsule (doxycycline 100 mg) taken orally once or twice daily, depending on the infection being treated. For acne, a lower dose may be used. For malaria prevention, it is typically taken once daily starting 1-2 days before travel and continuing for 4 weeks after leaving the area. The exact dose and duration must be individualized by a qualified clinician based on the indication, age, weight, renal and hepatic function.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician. This medicine is generally not recommended for children under 8 years of age due to the risk of permanent tooth discoloration.
Elderly DosageElderly patients may be more susceptible to the side effects of this medicine. Dose adjustment may be necessary based on renal and hepatic function. Consult a doctor for individualized dosing.
Renal ImpairmentDoxycycline is generally safe in patients with renal impairment, but dose adjustment may be needed in severe kidney disease. Consult a doctor for individualized dosing.
Hepatic ImpairmentDoxycycline should be used with caution in patients with liver disease. Dose adjustment may be necessary. Consult a doctor for individualized dosing.
Maximum Daily DoseThe maximum recommended daily dose is 200 mg of doxycycline, but this may vary based on the indication. Do not exceed the dose prescribed by your doctor.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With food
Take with meals
Reduces stomach upset.
Dairy products
Avoid within 2 hours
Calcium can reduce absorption of doxycycline.
Iron-rich foods
Avoid within 2 hours
Iron can reduce absorption of doxycycline.
Alcohol
Avoid
May worsen side effects and reduce probiotic effectiveness.

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of dxl 100 capsule

✅ Common Side Effects

Nausea (Common (5-10%))
Take with food or milk to reduce nausea. If it persists, consult your doctor.
Diarrhea (Common (5-10%))
Stay hydrated. If diarrhea is severe or persistent, contact your doctor.
Vomiting (Common (5-10%))
Take with a full glass of water and food. If vomiting occurs soon after taking the dose, consult your doctor.
Stomach pain (Common (5-10%))
Take with food. If pain is severe or persistent, seek medical advice.
Photosensitivity (Common (5-10%))
Avoid sun exposure, use sunscreen, and wear protective clothing.

🚨 Serious Side Effects

Severe allergic reaction (anaphylaxis) (Rare (<0.1%))
Seek immediate medical attention if you experience swelling of the face, lips, tongue, or throat, difficulty breathing, or a severe rash.
Liver toxicity (Rare (<0.1%))
Report yellowing of the skin or eyes, dark urine, or severe abdominal pain to your doctor immediately.
Severe skin reactions (Stevens-Johnson syndrome) (Rare (<0.1%))
Seek emergency care if you develop a painful rash with blisters, peeling skin, or sores in the mouth or eyes.
Intracranial hypertension (Rare (<0.1%))
Report severe headaches, vision changes, or ringing in the ears to your doctor promptly.

⚠️ Rare Side Effects

Esophageal ulceration
Take with plenty of water and remain upright for 30 minutes. Report severe chest pain or difficulty swallowing.
Blood dyscrasias
Report unusual bruising or bleeding to your doctor.
Pancreatitis
Seek medical attention for severe abdominal pain that radiates to the back.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Warfarin Major
Isotretinoin Major
Antacids Major
Iron supplements Major
Phenytoin Moderate
Carbamazepine Moderate
Methotrexate Moderate
Penicillins Minor
Oral contraceptives Minor
Alcohol Minor

🚨 Major Interactions

  • Warfarin
  • Isotretinoin
  • Antacids containing aluminum, calcium, or magnesium
  • Iron supplements

⚡ Moderate Interactions

  • Phenytoin
  • Carbamazepine
  • Methotrexate

🍷 Alcohol Interaction

Alcohol may worsen stomach upset and reduce the effectiveness of this medicine. It is advisable to avoid alcohol while taking this medicine.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Hypersensitivity to doxycycline or other tetracyclines","Pregnancy (especially after 15 weeks)","Breastfeeding without medical advice","Children under 8 years of age","Severe liver disease"]

⚠️ Warnings & Precautions

["Take with plenty of water to avoid esophageal irritation.","Avoid sun exposure and use sunscreen.","Do not take with antacids, iron, or calcium supplements within 2 hours.","May reduce the effectiveness of oral contraceptives; use backup contraception.","May cause photosensitivity; avoid tanning beds.","Do not use in children under 8 years due to risk of tooth discoloration.","Use with caution in patients with liver disease."]

🤱 Lactation Safety

Doxycycline is excreted in breast milk. Short-term use is generally considered compatible with breastfeeding, but prolonged use or high doses may affect the infant's teeth and bones. Consult your doctor before using this medicine while breastfeeding.

💊 Overdose Management

Overdose of this medicine may cause nausea, vomiting, and diarrhea. There is no specific antidote. Treatment is supportive and symptomatic. Seek immediate medical attention if you suspect an overdose.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up.

Additional Safety Advice

General Safety

Take this medicine with a full glass of water to reduce the risk of throat irritation and stomach upset. Do not lie down immediately after taking the capsule; stay upright for at least 30 minutes. Avoid direct sun exposure and use sunscreen while taking this medicine, as it can make your skin more sensitive to sunlight. Do not take antacids, calcium supplements, iron supplements, or multivitamins within two hours before or after this medicine, as they can reduce its absorption. Complete the full course prescribed by your doctor, even if you feel better after a few days. Do not use this medicine if you are pregnant or breastfeeding unless your doctor specifically advises it. Keep this medicine out of the reach of children.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients may be more susceptible to the side effects of this medicine, especially gastrointestinal and photosensitivity reactions. Dose adjustment may be necessary based on renal and hepatic function. Regular monitoring is advised.

🤰 Pregnancy Planning (TTC)

This medicine is not recommended during pregnancy. If you are planning to become pregnant, consult your doctor to discuss alternative treatments. Use effective contraception while taking this medicine.

🏥 Post-Surgery Considerations

If you are scheduled for surgery, inform your surgeon that you are taking this medicine. It may interact with certain anesthetics or affect wound healing. Your doctor may advise you to stop it before surgery.

🦷 Dental Procedures

Inform your dentist that you are taking this medicine before any dental procedure. It may affect the choice of antibiotics or anesthetics used. Also, this medicine can cause tooth discoloration in children under 8 years, so it is not recommended for them.

💚 Lifestyle Tips for Better Results

🏃
Stay well hydrated by drinking plenty of water.
🥗
Avoid excessive sun exposure and use sunscreen.
😴
Maintain a healthy diet rich in probiotics (e.g., yogurt) to support gut health, but avoid taking them within 2 hours of this medicine.
💧
Get adequate rest to help your body fight the infection.
🧘
Practice good hygiene to prevent the spread of infection.

🏋️ Exercise Considerations

This medicine may cause dizziness or photosensitivity. Avoid strenuous outdoor exercise during peak sun hours. If you experience dizziness, avoid driving or operating heavy machinery until you feel better.

🥗 Diet Recommendations

Include probiotic-rich foods like yogurt, but consume them at least 2 hours apart from this medicine.
Avoid dairy products, antacids, and iron supplements within 2 hours of taking this medicine.
Stay well hydrated.
Eat a balanced diet to support your immune system.

💼 Impact on Daily Work & Life

This medicine may cause dizziness or sensitivity to sunlight, which could affect your ability to drive or operate machinery. Avoid driving if you feel dizzy. Take precautions to protect your skin from the sun if you work outdoors.

🛑 When to Stop This Medicine

Do not stop taking this medicine without consulting your doctor, even if you feel better. Stopping early can lead to incomplete treatment and antibiotic resistance. If you experience severe side effects, contact your doctor immediately.

📅 Long-Term Use Effects

Long-term use of this medicine may lead to antibiotic resistance, gut flora imbalance, and rare side effects such as liver toxicity. It should only be used for the duration prescribed by your doctor. Regular monitoring may be required if used for prolonged periods.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Probiotic supplements

Can help maintain gut health during antibiotic therapy.

Evidence: Well-established
Topical treatments for acne

May be used as an alternative or in addition to oral antibiotics for acne.

Evidence: Well-established

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

This medicine does not interact with most vaccines. However, if you are scheduled to receive a live bacterial vaccine (e.g., typhoid vaccine), consult your doctor as antibiotics may affect its efficacy.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

When traveling, carry this medicine in its original packaging along with a copy of your prescription. Store it at room temperature and protect it from extreme heat or moisture. If you are traveling across time zones, consult your doctor about how to adjust your dosing schedule. Keep it in your carry-on luggage to avoid loss or temperature extremes. Check local customs regulations regarding prescription medicines before you travel.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 32-year-old woman with acne
She was prescribed this medicine for moderate acne. She took it regularly with food and used sunscreen as advised. After 4 weeks, her acne improved significantly. She also noticed less stomach upset compared to a previous antibiotic she had taken.
💡 Lesson: Taking this medicine with food and using sun protection can improve tolerability and outcomes.
👤 A 45-year-old man with a respiratory tract infection
He was prescribed this medicine for a bacterial respiratory infection. He completed the full 10-day course as directed. His symptoms resolved within a week, and he did not experience any severe side effects. He was advised to avoid dairy products within 2 hours of taking the medicine.
💡 Lesson: Completing the full course and following dietary restrictions are important for effective treatment.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: You may start feeling better within 1-2 days, but it may take a few days to a week for full effect. Complete the full course as prescribed.

Q: Can I take this medicine with food?

A: Yes, you can take it with food to reduce stomach upset. However, avoid dairy products, antacids, and iron supplements within 2 hours of taking it.

Q: What should I do if I miss a dose?

A: If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose.

Q: Is this medicine safe during pregnancy?

A: This medicine is not recommended during pregnancy as it can harm the developing fetus. Consult your doctor for alternative treatment options.

Q: Can I drink alcohol while taking this medicine?

A: It is advisable to avoid alcohol while taking this medicine as it may worsen side effects and reduce the effectiveness of the probiotic.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my kidney function?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?

🔄 Substitutes for dxl 100 capsule

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: This medicine can be taken with milk.
    Fact: Milk and dairy products can reduce the absorption of doxycycline. It is best taken with water, and dairy should be avoided within 2 hours of taking the medicine.
  • Myth: This medicine can be used to treat viral infections like the flu.
    Fact: This medicine is an antibiotic and is only effective against bacterial infections. It does not treat viral infections.
  • Myth: You can stop taking this medicine once you feel better.
    Fact: You must complete the full course prescribed by your doctor to prevent the infection from returning and to reduce the risk of antibiotic resistance.

🔄 Alternative Options

Generic Alternatives

  • Doxycycline 100 mg + Lactobacillus 5 million spores capsule

Brand Alternatives

  • DXL 100 Capsule

📊 Comparison with Similar Medicines

[{"medicine":"Doxycycline alone","difference":"Does not contain Lactobacillus, so may cause more gut-related side effects."},{"medicine":"Doxycycline + Lactobacillus","difference":"Contains a probiotic to help maintain gut flora during antibiotic therapy."}]

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