dxl 100 capsule - Doxycycline (100mg) + Lactobacillus (5Million spores) medicine

dxl 100 capsule

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🏭 Abrik Remedies Private Limited 📦 Varies by brand 💊 Allopathy 📅 Updated: Sep 15, 2026
📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Reviewed by
SaathiMed Expert Panel | Sep 15, 2026

What is dxl 100 capsule used for?

This medicine contains Doxycycline (100mg) + Lactobacillus (5Million spores) and is used to treat ANTI INFECTIVES. Doxycycline inhibits bacterial protein synthesis by binding to the 30S ribosomal subunit, preventing. Always consult your doctor before use.

  • Generic Name: Doxycycline + Lactobacillus
  • Manufacturer: Abrik Remedies Private Limited
  • Form: Allopathy
  • Pregnancy Category: Category A
  • Prescription Required: Yes
💡 Did You Know? The Indian pharmaceutical market is expected to reach $130 billion by 2030.

💊 dxl 100 capsule Uses & Benefits

Acne vulgaris, Rosacea, Respiratory tract infections, Urinary tract infections, Sexually transmitted infections (e.g., chlamydia, gonorrhea), Lyme disease, Malaria prophylaxis, Periodontal disease

Off-label uses: Scleroderma, Rheumatoid arthritis (as adjunct), Chronic prostatitis

📋 Drug Information

Generic Name(s)Doxycycline + Lactobacillus
Brand NameAdoxy LB Capsule
ManufacturerAbrik Remedies Private Limited
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassANTI INFECTIVES
Action ClassTetracycline Antibiotic + Probiotic
Route of AdministrationOral
StorageStore at room temperature (20-25°C), protect from light and moisture.
Shelf LifeAs per manufacturer

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionDoxycycline is almost completely absorbed after oral administration; absorption is not significantly affected by food or milk. Lactobacillus is not absorbed.
DistributionDoxycycline is widely distributed into tissues and body fluids, including cerebrospinal fluid; crosses placenta and enters breast milk.
Protein BindingDoxycycline: 80-90% bound to plasma proteins.
MetabolismDoxycycline is partially metabolized in the liver via glucuronidation.
Half-LifeDoxycycline: 18-22 hours (single dose), up to 22-24 hours with multiple doses.
ExcretionDoxycycline: primarily excreted in feces (via bile) and urine (about 40%). Lactobacillus is eliminated in feces.
BioavailabilityDoxycycline: approximately 90-100%.
Onset of ActionDoxycycline: 1-2 hours.
Peak Plasma TimeDoxycycline: 2-4 hours.
Duration of ActionDoxycycline: 12-24 hours.

How It Works

Doxycycline inhibits bacterial protein synthesis by binding to the 30S ribosomal subunit, preventing aminoacyl-tRNA binding. Lactobacillus restores intestinal flora.

Mechanism Steps

1Doxycycline enters bacterial cell via passive diffusion and active transport.
2Binds reversibly to the 30S ribosomal subunit.
3Prevents binding of aminoacyl-tRNA to the mRNA-ribosome complex.
4Inhibits protein synthesis, leading to bacteriostatic effect.
5Lactobacillus colonizes the gut and restores normal flora, reducing antibiotic-associated diarrhea.

💡 How to Take dxl 100 capsule

Follow your doctor's prescription exactly.

⚠️ Side Effects of dxl 100 capsule

✅ Common Side Effects

Nausea
Vomiting
Diarrhea
Photosensitivity
Esophageal irritation
Vaginal candidiasis

🚨 Serious Side Effects

Pseudomembranous colitis
Stevens-Johnson syndrome
Toxic epidermal necrolysis
Intracranial hypertension
Hepatotoxicity
Nephrotoxicity

⚠️ Rare Side Effects

Blood dyscrasias
Anaphylaxis
Pericarditis
Pancreatitis
Thyroid discoloration

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Warfarin Major Increased anticoagulant effect and bleeding risk
Oral contraceptives Major Reduced contraceptive efficacy
Penicillins Major Antagonistic antibacterial effect
Antacids (Al, Ca, Mg) Major Reduced doxycycline absorption
Iron supplements Major Reduced doxycycline absorption
Bismuth subsalicylate Major Reduced doxycycline absorption
Methoxyflurane Moderate Increased risk of nephrotoxicity
Retinoids Moderate Increased risk of pseudotumor cerebri
Barbiturates Moderate Decreased doxycycline half-life
Carbamazepine Moderate Decreased doxycycline half-life
Phenytoin Moderate Decreased doxycycline half-life
Digoxin Minor Possible increased digoxin levels
Lithium Minor Possible increased lithium levels
Methotrexate Minor Possible increased methotrexate toxicity

🚨 Major Interactions

  • Warfarin
  • Oral contraceptives
  • Penicillins
  • Antacids containing aluminum, calcium, magnesium
  • Iron supplements
  • Bismuth subsalicylate

⚡ Moderate Interactions

  • Methoxyflurane
  • Retinoids
  • Barbiturates
  • Carbamazepine
  • Phenytoin

🍷 Alcohol Interaction

Alcohol may reduce effectiveness and increase risk of hepatotoxicity; avoid concurrent use.

🛡️ Safety & Warnings

🚫 Contraindications

Hypersensitivity to doxycycline or any tetracycline, Pregnancy, Lactation, Children under 8 years (risk of permanent tooth discoloration), Severe hepatic impairment

🤱 Lactation Safety

Doxycycline is excreted in breast milk; avoid breastfeeding or use with caution due to risk of denta

💊 Overdose Management

Induce vomiting or gastric lavage; administer activated charcoal; supportive care. No specific antidote.

⏰ Missed Dose

Take as soon as remembered unless near next dose; do not double dose.

🔄 Substitutes for dxl 100 capsule

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

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