dorsun eye drop - Dorzolamide (2% w/v) medicine

dorsun eye drop

No reviews yet
🏭 Sunways India Pvt Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Sep 23, 2026
📋 Prescription Required 💊 Generic Available
Medically Reviewed
12 min read
Reviewed by
SaathiMed Expert Panel | Sep 23, 2026

What is dorsun eye drop used for?

This medicine contains Dorzolamide (2% w/v) and is used to treat OPHTHAL. Inhibits carbonic anhydrase II in the ciliary processes of the eye, reducing aqueous humor secretion. Always consult your doctor before use.

  • Generic Name: Dorzolamide
  • Manufacturer: Sunways India Pvt Ltd
  • Form: Allopathy
  • Pregnancy Category: Category C
  • Prescription Required: Yes
💡 Did You Know? India has the highest number of USFDA-compliant plants outside the USA.

💊 dorsun eye drop Uses & Benefits

Treatment of elevated intraocular pressure in ocular hypertension or open-angle glaucoma.

Off-label uses: Cystoid macular edema, Pseudotumor cerebri

📋 Drug Information

Generic Name(s)Dorzolamide
Brand NameDorzox
ManufacturerSunways India Pvt Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassOPHTHAL
Action ClassCarbonic anhydrase inhibitor
Route of AdministrationOphthalmic (eye drops)
StorageStore at 15-30°C (59-86°F). Protect from light. Keep bottle tightly closed.
Shelf LifeAs per manufacturer

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionAbsorbed systemically after ocular administration; peak plasma concentrations reached within 1-2 hours.
DistributionDistributes into erythrocytes due to binding to carbonic anhydrase; volume of distribution not well defined.
Protein BindingApproximately 33% bound to plasma proteins.
MetabolismMetabolized in the liver to N-desethyl dorzolamide, which is less active.
Half-LifePlasma half-life is about 4 months due to accumulation in erythrocytes; elimination half-life from e
ExcretionExcreted primarily in urine as unchanged drug and metabolites.
BioavailabilitySystemic bioavailability after ocular administration is low due to limited absorption.
Onset of ActionReduction in intraocular pressure begins within 1-2 hours after administration.
Peak Plasma TimePeak plasma concentrations occur 1-2 hours after ocular administration.
Duration of ActionDuration of action is approximately 8-12 hours.

How It Works

Inhibits carbonic anhydrase II in the ciliary processes of the eye, reducing aqueous humor secretion and lowering intraocular pressure.

Mechanism Steps

1Dorzolamide is administered as eye drops and penetrates the cornea.
2It reaches the ciliary processes of the eye.
3Inhibits carbonic anhydrase II enzyme in the ciliary epithelium.
4Reduces formation of bicarbonate ions from carbon dioxide and water.
5Decreases sodium and fluid transport into the posterior chamber.
6Reduces aqueous humor secretion.
7Lowers intraocular pressure.

💡 How to Take dorsun eye drop

Follow your doctor's prescription exactly.

⚠️ Side Effects of dorsun eye drop

✅ Common Side Effects

Stinging and burning sensation
Blurred vision
Bitter taste
Eye irritation
Headache
Nausea
Fatigue

🚨 Serious Side Effects

Stevens-Johnson syndrome
Toxic epidermal necrolysis
Metabolic acidosis
Renal calculi
Corneal edema

⚠️ Rare Side Effects

Uveitis
Iritis
Transient myopia
Hypokalemia
Paresthesia

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Acetazolamide Major Additive effect on lowering intraocular pressure and increased risk of metabolic acidosis.
Aspirin Moderate Increased risk of salicylate toxicity due to competition for renal excretion.
Corticosteroids Moderate May increase intraocular pressure, counteracting effect of dorzolamide.

🚨 Major Interactions

  • Acetazolamide
  • Methazolamide
  • Sulfonamides

⚡ Moderate Interactions

  • Aspirin
  • Salicylates
  • Corticosteroids

🍷 Alcohol Interaction

No known interaction.

🛡️ Safety & Warnings

🚫 Contraindications

Severe renal impairment (CrCl

🤱 Lactation Safety

Not recommended; unknown if excreted in human milk.

💊 Overdose Management

If accidentally ingested, induce vomiting or perform gastric lavage. Monitor electrolytes and acid-base balance. Supportive care.

⏰ Missed Dose

Apply the missed dose as soon as remembered. If it is almost time for the next dose, skip the missed dose. Do not double the dose.

🔄 Substitutes for dorsun eye drop

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

😊 Was this information helpful?

Browse Medicines A-Z

A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
Back to Medicines Directory