Dicarb 100mg Tablet (Diethylcarbamazine): Complete Medicine Guide
When to Call Your Doctor IMMEDIATELY
- Swelling of the face, lips, tongue, or throat.
- Difficulty breathing or wheezing.
- Severe skin rash or blistering.
- High fever with chills and severe weakness.
- Yellowing of the skin or eyes (jaundice).
- Dark urine or decreased urine output.
- Severe abdominal pain or vomiting blood.
- Confusion, seizures, or loss of consciousness.
If experiencing severe symptoms, call emergency services immediately.
What is dicarb 100mg tablet used for?
This medicine contains Diethylcarbamazine 100 mg, an antifilarial medicine used to treat lymphatic filariasis and other filarial infections. It works by killing the microfilariae and adult worms. It is taken orally, usually after meals, for 12 to 21 days depending on the infection. Common side effects include nausea, headache, and dizziness. Serious reactions like the Mazzotti reaction can occur. Always take it under medical supervision.
- Generic Name: Diethylcarbamazine
- Manufacturer: Inga Laboratories Pvt Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 dicarb 100mg tablet के बारे में (Hindi Summary)
उपयोग: यह दवा डाइएथिलकार्बामाज़ीन 100 मिलीग्राम युक्त एक एंटीफाइलेरियल दवा है, जिसका उपयोग लिम्फैटिक फाइलेरिया (हाथी पांव) और अन्य फाइलेरियल संक्रमणों के इलाज के लिए किया जाता है। यह परजीवी के माइक्रोफाइलेरिया और वयस्क कीड़ों को मारकर काम करती है। यह मलेरिया नहीं है, बल्कि मच्छर के काटने से फैलने वाला संक्रमण है। इस दवा को डॉक्टर के निर्देशानुसार भोजन के बाद लेना चाहिए। आमतौर पर 12 से 21 दिनों तक चलता है। इसके सामान्य दुष्प्रभावों में जी मिचलाना, सिरदर्द और चक्कर आना शामिल हैं। गंभीर मामलों में माज़ोटी प्रतिक्रिया हो सकती है, जिसमें बुखार, दाने और सूजन हो सकती है। इस दवा को बिना डॉक्टर की सलाह के नहीं लेना चाहिए।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में जी मिचलाना, उल्टी, भूख न लगना, सिरदर्द, चक्कर आना और नींद आना शामिल हैं। कुछ रोगियों को जोड़ों और मांसपेशियों में दर्द या असहजता महसूस हो सकती है। माज़ोटी प्रतिक्रिया एक गंभीर प्रतिक्रिया है जो अक्सर उन रोगियों में होती है जिनके शरीर में परजीवी की संख्या अधिक होती है। इसमें बुखार, ठंड लगना, त्वचा पर दाने, खुजली, लिम्फ नोड्स में सूजन और तेज़ धड़कन शामिल हो सकते हैं। यह प्रतिक्रिया आमतौर पर इलाज के पहले कुछ दिनों में होती है। गंभीर एलर्जी प्रतिक्रिया दुर्लभ है लेकिन चेहरे, होंठ, जीभ या गले में सूजन, सांस लेने में कठिनाई या गंभीर त्वचा पर दाने हो सकते हैं। ऐसे लक्षण दिखने पर तुरंत डॉक्टर से मिलें।
सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। अपने आप मात्रा कम या ज्यादा न करें। गोली को पानी के साथ निगलें, बेहतर होगा कि भोजन के बाद लें ताकि पेट खराब न हो। अगर आपको खुराक लेना भूल जाए, तो याद आते ही ले लें, लेकिन अगर अगली खुराक का समय नज़दीक हो, तो छूटी हुई खुराक छोड़ दें और सामान्य कार्यक्रम जारी रखें। दोहरी खुराक न लें। अगर आपको चक्कर या नींद आती है तो वाहन चलाने या मशीनरी चलाने से बचें। अगर आप गर्भवती हैं, गर्भवती होने की योजना बना रही हैं या स्तनपान करा रही हैं, तो अपने डॉक्टर को बताएं। बेहतर महसूस होने पर भी दवा बंद न करें, क्योंकि इससे संक्रमण फिर से हो सकता है। इस दवा को बच्चों की पहुंच से दूर रखें और ठंडी, सूखी जगह पर सूरज की सीधी रोशनी से बचाकर रखें।
💊 dicarb 100mg tablet Uses & Benefits
- [{"condition":"Lymphatic filariasis","description":"This medicine is used to treat lymphatic filariasis caused by Wuchereria bancrofti, Brugia malayi, and Brugia timori.
- It kills the microfilariae and adult worms, helping to reduce symptoms and prevent transmission.","evidence":"Well-established"},{"condition":"Tropical pulmonary eosinophilia","description":"This medicine is effective in treating tropical pulmonary eosinophilia, a condition characterized by coughing, wheezing, and eosinophilia due to filarial infection.","evidence":"Well-established"},{"condition":"Loiasis (African eye worm)","description":"This medicine is used to treat loiasis caused by Loa loa, although treatment may require careful monitoring due to the risk of severe reactions.","evidence":"Established"},{"condition":"Mansonelliasis","description":"This medicine may be used to treat mansonelliasis, a filarial infection caused by Mansonella species, though evidence is more limited.","evidence":"Limited"}]
Off-label uses: [{"condition":"Cutaneous larva migrans","description":"This medicine has been used off-label for cutaneous larva migrans, a skin infection caused by hookworm larvae, but it is not a first-line treatment.","evidence":"Limited"},{"condition":"Ascariasis","description":"This medicine has some activity against Ascaris lumbricoides, but it is not routinely recommended for this purpose.","evidence":"Limited"}]
Primary treatment for: Lymphatic filariasis
Also treats: Tropical pulmonary eosinophilia, Loiasis, Mansonelliasis
📋 Drug Information
| Generic Name(s) | Diethylcarbamazine |
| Brand Name | Banocide |
| Manufacturer | Inga Laboratories Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | ANTI INFECTIVES |
| Action Class | Antiprotozoal agents |
| Route of Administration | Oral |
| Storage | Store at room temperature (15-30°C) in a cool, dry place away from direct sunlight. Keep in the original container. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | The World Health Organization recommends diethylcarbamazine as part of mass drug administration for lymphatic filariasis elimination, often in combination with albendazole or ivermectin. |
| ICMR Guideline | The Indian Council of Medical Research recommends diethylcarbamazine for the treatment of lymphatic filariasis in India, following national guidelines. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine works by interfering with the metabolism of arachidonic acid in the filarial parasites, leading to the production of toxic prostaglandins and other metabolites that damage the parasite. It also alters the parasite's cell membrane, making it more susceptible to destruction by the host's immune system. The exact mechanism is not fully understood, but it is believed to involve both direct effects on the parasite and enhancement of the host's immune response against the microfilariae.
Mechanism Steps
💡 How to Take dicarb 100mg tablet
Strength: Diethylcarbamazine 100 mg immediate-release tablet.
Dosage Information
| Adult Dosage | The usual adult dose of this medicine for lymphatic filariasis is 6 mg per kg of body weight per day, given in three divided doses after meals for 12 days. For tropical pulmonary eosinophilia, the dose is 6 mg per kg per day for 14 to 21 days. For loiasis, the dose may be lower and gradually increased to avoid severe reactions. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients may have reduced renal function and may require dose adjustment. Use with caution and monitor renal function. |
| Renal Impairment | In patients with renal impairment, the dose may need to be reduced. Consult your doctor for individualized dosing. |
| Hepatic Impairment | In patients with hepatic impairment, use with caution. Dose adjustment may be necessary. Consult your doctor. |
| Maximum Daily Dose | The maximum daily dose is not established from available information. Follow your doctor's prescription. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of dicarb 100mg tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Suramin | Major | |
| Warfarin | Major | |
| Corticosteroids | Moderate | |
| Antihistamines | Moderate | |
| Alcohol | Minor |
🚨 Major Interactions
- Suramin
- Anticoagulants (e.g., warfarin)
⚡ Moderate Interactions
- Corticosteroids
- Antihistamines
🍷 Alcohol Interaction
Alcohol may increase the sedative effects of this medicine, leading to increased drowsiness and dizziness. It is advisable to avoid alcohol while taking this medicine.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Known hypersensitivity to Diethylcarbamazine or any component of the formulation.","Severe renal impairment (dose adjustment required, may be contraindicated).","Severe hepatic impairment.","Concurrent use with suramin (due to increased risk of severe reactions)."]
⚠️ Warnings & Precautions
["This medicine may cause the Mazzotti reaction, especially in patients with high microfilarial loads. This reaction can be severe and may require medical management.","Use with caution in patients with renal or hepatic impairment. Dose adjustment may be necessary.","This medicine may cause drowsiness or dizziness. Avoid driving or operating machinery until you know how it affects you.","Do not use this medicine for self-medication. It should only be taken under medical supervision.","Inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding.","Keep this medicine out of reach of children.","Do not share this medicine with others."]
🤱 Lactation Safety
This medicine is excreted in breast milk. It is generally considered safe for use during breastfeeding, but consult your doctor to weigh the benefits and risks.
💊 Overdose Management
Overdose of this medicine may cause nausea, vomiting, dizziness, and drowsiness. In severe cases, it may lead to seizures or coma. If you suspect an overdose, seek immediate medical attention. Treatment is supportive and symptomatic. There is no specific antidote.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up.
Additional Safety Advice
Take this medicine exactly as prescribed by your doctor. Do not take more or less than the recommended dose. Swallow the tablet whole with a glass of water, preferably after a meal to reduce stomach upset. If you miss a dose, take it as soon as you remember, but if it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose. Avoid driving or operating heavy machinery if you feel dizzy or drowsy after taking this medicine. Inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding. Your doctor may adjust the dose or recommend an alternative. Do not stop taking this medicine without consulting your doctor, even if you feel better, as stopping early may allow the infection to return. Keep this medicine out of reach of children and store it in a cool, dry place away from direct sunlight. Do not share this medicine with others, even if they have similar symptoms.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients may have reduced kidney function and may require dose adjustment. Close monitoring for side effects is advised.
🤰 Pregnancy Planning (TTC)
If you are planning to become pregnant, consult your doctor before taking this medicine. It should be used during pregnancy only if clearly needed.
🏥 Post-Surgery Considerations
Inform your surgeon and anesthesiologist that you are taking this medicine before any surgery. It may need to be stopped temporarily.
🦷 Dental Procedures
Inform your dentist that you are taking this medicine before any dental procedure. No specific precautions are usually needed, but it is important for your dentist to know your medication history.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
If you have lymphedema, avoid strenuous exercise that may worsen swelling. Gentle exercises like walking and swimming can help improve circulation. Consult your doctor before starting any exercise program.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause dizziness or drowsiness. Avoid driving or operating heavy machinery until you know how it affects you. Most people can continue their normal daily activities with caution.
🛑 When to Stop This Medicine
Do not stop taking this medicine without consulting your doctor. Complete the full course as prescribed. If you experience severe side effects, contact your doctor immediately for advice.
📅 Long-Term Use Effects
Long-term use of this medicine is generally not required for filarial infections, as treatment courses are typically 12 to 21 days. However, in rare cases of prolonged use, monitoring of liver and kidney function may be advised. There is no evidence of significant long-term toxicity when used as prescribed.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Another antifilarial medicine that may be used alone or in combination with other drugs.
Evidence: Well-establishedOften used in combination with diethylcarbamazine or ivermectin for mass drug administration.
Evidence: Well-establishedMay be used as an adjunct to target Wolbachia bacteria that live inside the filarial worms.
Evidence: Emerging💉 Vaccination Considerations
💉 If You're Getting Vaccinated
There are no known interactions between this medicine and vaccines. However, consult your doctor before receiving any vaccine while on this medicine.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
When traveling, carry this medicine in its original packaging along with a copy of your prescription. Store it at room temperature and protect it from direct sunlight and moisture. If you are crossing time zones, adjust your dosing schedule gradually to avoid missing doses. Check the customs regulations of your destination country regarding prescription medicines. Always carry enough supply for your entire trip.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: This medicine starts killing microfilariae within hours, but clinical improvement may take several days to weeks. Complete the full course as prescribed.
A: Yes, it is best taken after a meal to reduce stomach upset.
A: Take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose.
A: Consult your doctor. It should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus.
A: No, you must complete the full course as prescribed to ensure the infection is fully cleared and to prevent recurrence.
🤔 Common Patient Concerns
🔄 Substitutes for dicarb 100mg tablet
View AllAlternative brands with exact same active ingredient:
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esnotone tabletSarmain Pharmaceuticals ₹8.00 52.4% CHEAPER
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filocar 100 tabletZeelab Pharmacy Pvt Ltd ₹9.90 41.1% CHEAPER
-
deecee 100mg tabletShrinivas Gujarat Laboratories Pvt Ltd ₹16.00 4.8% CHEAPER
-
banocide forte tabletGlaxo SmithKline Pharmaceuticals Ltd ₹52.61 213% COSTLIER
-
benocide 100mg forte tabletGlaxo SmithKline Pharmaceuticals Ltd ₹52.61 213% COSTLIER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can cure all types of worm infections.
Fact: This medicine is specifically effective against filarial worms. It is not a broad-spectrum deworming medicine. - Myth: You can stop taking this medicine as soon as symptoms improve.
Fact: You must complete the full course as prescribed to ensure the infection is fully cleared and to prevent recurrence. - Myth: This medicine is safe to take without a prescription.
Fact: This medicine should only be taken under medical supervision. Self-medication can lead to serious side effects.
🔄 Alternative Options
Generic Alternatives
- Diethylcarbamazine 100 mg tablet (generic)
Brand Alternatives
- Dicarb 100mg tablet