dicarb 100mg tablet - Diethylcarbamazine (100mg) medicine

Dicarb 100mg Tablet (Diethylcarbamazine): Complete Medicine Guide

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🏭 Inga Laboratories Pvt Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Sep 21, 2026
⚠️ Hepatotoxicity Risk ⚠️ Nephrotoxicity Risk 📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Well-established for filarial infections.
Reviewed by
SaathiMed Expert Panel | Sep 21, 2026

When to Call Your Doctor IMMEDIATELY

  • Swelling of the face, lips, tongue, or throat.
  • Difficulty breathing or wheezing.
  • Severe skin rash or blistering.
  • High fever with chills and severe weakness.
  • Yellowing of the skin or eyes (jaundice).
  • Dark urine or decreased urine output.
  • Severe abdominal pain or vomiting blood.
  • Confusion, seizures, or loss of consciousness.

If experiencing severe symptoms, call emergency services immediately.

What is dicarb 100mg tablet used for?

This medicine contains Diethylcarbamazine 100 mg, an antifilarial medicine used to treat lymphatic filariasis and other filarial infections. It works by killing the microfilariae and adult worms. It is taken orally, usually after meals, for 12 to 21 days depending on the infection. Common side effects include nausea, headache, and dizziness. Serious reactions like the Mazzotti reaction can occur. Always take it under medical supervision.

  • Generic Name: Diethylcarbamazine
  • Manufacturer: Inga Laboratories Pvt Ltd
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 dicarb 100mg tablet के बारे में (Hindi Summary)

उपयोग: यह दवा डाइएथिलकार्बामाज़ीन 100 मिलीग्राम युक्त एक एंटीफाइलेरियल दवा है, जिसका उपयोग लिम्फैटिक फाइलेरिया (हाथी पांव) और अन्य फाइलेरियल संक्रमणों के इलाज के लिए किया जाता है। यह परजीवी के माइक्रोफाइलेरिया और वयस्क कीड़ों को मारकर काम करती है। यह मलेरिया नहीं है, बल्कि मच्छर के काटने से फैलने वाला संक्रमण है। इस दवा को डॉक्टर के निर्देशानुसार भोजन के बाद लेना चाहिए। आमतौर पर 12 से 21 दिनों तक चलता है। इसके सामान्य दुष्प्रभावों में जी मिचलाना, सिरदर्द और चक्कर आना शामिल हैं। गंभीर मामलों में माज़ोटी प्रतिक्रिया हो सकती है, जिसमें बुखार, दाने और सूजन हो सकती है। इस दवा को बिना डॉक्टर की सलाह के नहीं लेना चाहिए।

साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में जी मिचलाना, उल्टी, भूख न लगना, सिरदर्द, चक्कर आना और नींद आना शामिल हैं। कुछ रोगियों को जोड़ों और मांसपेशियों में दर्द या असहजता महसूस हो सकती है। माज़ोटी प्रतिक्रिया एक गंभीर प्रतिक्रिया है जो अक्सर उन रोगियों में होती है जिनके शरीर में परजीवी की संख्या अधिक होती है। इसमें बुखार, ठंड लगना, त्वचा पर दाने, खुजली, लिम्फ नोड्स में सूजन और तेज़ धड़कन शामिल हो सकते हैं। यह प्रतिक्रिया आमतौर पर इलाज के पहले कुछ दिनों में होती है। गंभीर एलर्जी प्रतिक्रिया दुर्लभ है लेकिन चेहरे, होंठ, जीभ या गले में सूजन, सांस लेने में कठिनाई या गंभीर त्वचा पर दाने हो सकते हैं। ऐसे लक्षण दिखने पर तुरंत डॉक्टर से मिलें।

सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। अपने आप मात्रा कम या ज्यादा न करें। गोली को पानी के साथ निगलें, बेहतर होगा कि भोजन के बाद लें ताकि पेट खराब न हो। अगर आपको खुराक लेना भूल जाए, तो याद आते ही ले लें, लेकिन अगर अगली खुराक का समय नज़दीक हो, तो छूटी हुई खुराक छोड़ दें और सामान्य कार्यक्रम जारी रखें। दोहरी खुराक न लें। अगर आपको चक्कर या नींद आती है तो वाहन चलाने या मशीनरी चलाने से बचें। अगर आप गर्भवती हैं, गर्भवती होने की योजना बना रही हैं या स्तनपान करा रही हैं, तो अपने डॉक्टर को बताएं। बेहतर महसूस होने पर भी दवा बंद न करें, क्योंकि इससे संक्रमण फिर से हो सकता है। इस दवा को बच्चों की पहुंच से दूर रखें और ठंडी, सूखी जगह पर सूरज की सीधी रोशनी से बचाकर रखें।

💡 Did You Know? Over 80% of the antiretroviral drugs used globally to combat AIDS are supplied by Indian pharmaceutical companies.

💊 dicarb 100mg tablet Uses & Benefits

  • [{"condition":"Lymphatic filariasis","description":"This medicine is used to treat lymphatic filariasis caused by Wuchereria bancrofti, Brugia malayi, and Brugia timori.
  • It kills the microfilariae and adult worms, helping to reduce symptoms and prevent transmission.","evidence":"Well-established"},{"condition":"Tropical pulmonary eosinophilia","description":"This medicine is effective in treating tropical pulmonary eosinophilia, a condition characterized by coughing, wheezing, and eosinophilia due to filarial infection.","evidence":"Well-established"},{"condition":"Loiasis (African eye worm)","description":"This medicine is used to treat loiasis caused by Loa loa, although treatment may require careful monitoring due to the risk of severe reactions.","evidence":"Established"},{"condition":"Mansonelliasis","description":"This medicine may be used to treat mansonelliasis, a filarial infection caused by Mansonella species, though evidence is more limited.","evidence":"Limited"}]

Off-label uses: [{"condition":"Cutaneous larva migrans","description":"This medicine has been used off-label for cutaneous larva migrans, a skin infection caused by hookworm larvae, but it is not a first-line treatment.","evidence":"Limited"},{"condition":"Ascariasis","description":"This medicine has some activity against Ascaris lumbricoides, but it is not routinely recommended for this purpose.","evidence":"Limited"}]

Primary treatment for: Lymphatic filariasis

Also treats: Tropical pulmonary eosinophilia, Loiasis, Mansonelliasis

📋 Drug Information

Generic Name(s)Diethylcarbamazine
Brand NameBanocide
ManufacturerInga Laboratories Pvt Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassANTI INFECTIVES
Action ClassAntiprotozoal agents
Route of AdministrationOral
StorageStore at room temperature (15-30°C) in a cool, dry place away from direct sunlight. Keep in the original container.
Shelf Life24 months from the date of manufacture.
WHO GuidelineThe World Health Organization recommends diethylcarbamazine as part of mass drug administration for lymphatic filariasis elimination, often in combination with albendazole or ivermectin.
ICMR GuidelineThe Indian Council of Medical Research recommends diethylcarbamazine for the treatment of lymphatic filariasis in India, following national guidelines.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Take this medicine after a meal to reduce the risk of nausea and stomach upset.
2
Stay well hydrated throughout the day while taking this medicine.
3
Avoid alcohol while taking this medicine as it can increase drowsiness and dizziness.
4
Do not drive or operate heavy machinery until you know how this medicine affects you.
5
Complete the full course as prescribed, even if you feel better, to prevent recurrence of the infection.
6
Report any signs of the Mazzotti reaction, such as fever, rash, or swollen lymph nodes, to your doctor immediately.
7
Inform your doctor if you have kidney or liver problems before starting this medicine.
8
Do not share this medicine with others, even if they have similar symptoms.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

Swelling in legs or arms (lymphedema)
This medicine is commonly prescribed for lymphatic filariasis.
Likely Use
Chronic cough and wheezing
This medicine may be used for tropical pulmonary eosinophilia.
Likely Use
Fever
This medicine is not a primary fever reducer.
Not Primary
Skin itching
This medicine may help with itching due to filarial infection.
Likely Use

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionThis medicine is rapidly absorbed from the gastrointestinal tract after oral administration. The presence of food may delay absorption slightly but does not significantly affect the extent of absorption.
DistributionThis medicine is widely distributed throughout the body, including into the bloodstream, lymphatics, and tissues. It crosses the blood-brain barrier to some extent and is also found in breast milk.
Protein BindingNot established from the available information.
MetabolismThis medicine is partially metabolized in the liver, but the exact metabolic pathways are not fully characterized.
Half-LifeThe elimination half-life of this medicine is approximately 8 to 12 hours, but it may be prolonged in patients with renal impairment.
ExcretionThis medicine and its metabolites are primarily excreted in the urine. A smaller amount is excreted in the feces.
BioavailabilityThe oral bioavailability of this medicine is high, though exact values are not well established.
Onset of ActionThe effect on microfilariae begins within hours after the first dose, but clinical improvement may take several days to weeks.
Peak Plasma TimePeak plasma concentrations are reached within 1 to 2 hours after oral administration.
Duration of ActionThe effect on microfilariae lasts for several days, but repeated doses are needed to clear the infection completely.

How It Works

This medicine works by interfering with the metabolism of arachidonic acid in the filarial parasites, leading to the production of toxic prostaglandins and other metabolites that damage the parasite. It also alters the parasite's cell membrane, making it more susceptible to destruction by the host's immune system. The exact mechanism is not fully understood, but it is believed to involve both direct effects on the parasite and enhancement of the host's immune response against the microfilariae.

Mechanism Steps

1
Uptake by parasites: This medicine is taken up by the filarial parasites, where it accumulates.
2
Disruption of arachidonic acid metabolism: Inside the parasite, this medicine interferes with the metabolism of arachidonic acid, leading to the production of toxic metabolites.
3
Damage to microfilariae: The toxic metabolites damage the microfilariae, causing them to die and be cleared from the bloodstream.
4
Immune system activation: The dying microfilariae release antigens that stimulate the host's immune system, leading to further destruction of the parasites.

💡 How to Take dicarb 100mg tablet

Strength: Diethylcarbamazine 100 mg immediate-release tablet.

1Take this medicine exactly as prescribed by your doctor.
2Swallow the tablet whole with a glass of water.
3Take it after a meal to reduce stomach upset.
4Do not crush or chew the tablet unless instructed.
5If you miss a dose, follow the missed dose instructions.
6Do not stop taking this medicine without consulting your doctor.

Dosage Information

Adult DosageThe usual adult dose of this medicine for lymphatic filariasis is 6 mg per kg of body weight per day, given in three divided doses after meals for 12 days. For tropical pulmonary eosinophilia, the dose is 6 mg per kg per day for 14 to 21 days. For loiasis, the dose may be lower and gradually increased to avoid severe reactions. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageElderly patients may have reduced renal function and may require dose adjustment. Use with caution and monitor renal function.
Renal ImpairmentIn patients with renal impairment, the dose may need to be reduced. Consult your doctor for individualized dosing.
Hepatic ImpairmentIn patients with hepatic impairment, use with caution. Dose adjustment may be necessary. Consult your doctor.
Maximum Daily DoseThe maximum daily dose is not established from available information. Follow your doctor's prescription.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With food
Take with meals
Reduces stomach upset and nausea.
Alcohol
Avoid
May increase drowsiness and dizziness.

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of dicarb 100mg tablet

✅ Common Side Effects

Nausea (Common (5-10%))
Take the medicine with food to reduce nausea. If it persists, consult your doctor.
Vomiting (Common (5-10%))
Stay hydrated and take the medicine with a meal. If vomiting is severe, contact your doctor.
Headache (Common (5-10%))
Rest and stay hydrated. Over-the-counter pain relievers may help, but consult your doctor before taking them.
Dizziness (Common (5-10%))
Avoid driving or operating machinery until you know how this medicine affects you.
Drowsiness (Common (5-10%))
Avoid activities requiring alertness. If drowsiness is excessive, consult your doctor.
Joint pain (Uncommon (1-5%))
Rest and apply warm compresses. If pain is severe, consult your doctor.
Muscle pain (Uncommon (1-5%))
Gentle stretching and warm baths may help. Consult your doctor if it persists.

🚨 Serious Side Effects

Mazzotti reaction (Common in patients with high microfilarial loads)
Seek immediate medical attention if you experience fever, chills, rash, itching, swollen lymph nodes, or rapid heartbeat after starting this medicine.
Severe allergic reaction (anaphylaxis) (Rare (<0.1%))
Call emergency services if you experience swelling of the face, lips, tongue, or throat, difficulty breathing, or a severe skin rash.
Liver toxicity (Rare (<0.1%))
Report yellowing of the skin or eyes, dark urine, or severe abdominal pain to your doctor immediately.
Kidney toxicity (Rare (<0.1%))
Report decreased urine output, swelling in the legs, or fatigue to your doctor immediately.

⚠️ Rare Side Effects

Encephalopathy
Seek immediate medical attention if you experience confusion, seizures, or loss of consciousness.
Retinopathy
Report any changes in vision to your doctor promptly.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Suramin Major
Warfarin Major
Corticosteroids Moderate
Antihistamines Moderate
Alcohol Minor

🚨 Major Interactions

  • Suramin
  • Anticoagulants (e.g., warfarin)

⚡ Moderate Interactions

  • Corticosteroids
  • Antihistamines

🍷 Alcohol Interaction

Alcohol may increase the sedative effects of this medicine, leading to increased drowsiness and dizziness. It is advisable to avoid alcohol while taking this medicine.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Known hypersensitivity to Diethylcarbamazine or any component of the formulation.","Severe renal impairment (dose adjustment required, may be contraindicated).","Severe hepatic impairment.","Concurrent use with suramin (due to increased risk of severe reactions)."]

⚠️ Warnings & Precautions

["This medicine may cause the Mazzotti reaction, especially in patients with high microfilarial loads. This reaction can be severe and may require medical management.","Use with caution in patients with renal or hepatic impairment. Dose adjustment may be necessary.","This medicine may cause drowsiness or dizziness. Avoid driving or operating machinery until you know how it affects you.","Do not use this medicine for self-medication. It should only be taken under medical supervision.","Inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding.","Keep this medicine out of reach of children.","Do not share this medicine with others."]

🤱 Lactation Safety

This medicine is excreted in breast milk. It is generally considered safe for use during breastfeeding, but consult your doctor to weigh the benefits and risks.

💊 Overdose Management

Overdose of this medicine may cause nausea, vomiting, dizziness, and drowsiness. In severe cases, it may lead to seizures or coma. If you suspect an overdose, seek immediate medical attention. Treatment is supportive and symptomatic. There is no specific antidote.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up.

Additional Safety Advice

General Safety

Take this medicine exactly as prescribed by your doctor. Do not take more or less than the recommended dose. Swallow the tablet whole with a glass of water, preferably after a meal to reduce stomach upset. If you miss a dose, take it as soon as you remember, but if it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose. Avoid driving or operating heavy machinery if you feel dizzy or drowsy after taking this medicine. Inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding. Your doctor may adjust the dose or recommend an alternative. Do not stop taking this medicine without consulting your doctor, even if you feel better, as stopping early may allow the infection to return. Keep this medicine out of reach of children and store it in a cool, dry place away from direct sunlight. Do not share this medicine with others, even if they have similar symptoms.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients may have reduced kidney function and may require dose adjustment. Close monitoring for side effects is advised.

🤰 Pregnancy Planning (TTC)

If you are planning to become pregnant, consult your doctor before taking this medicine. It should be used during pregnancy only if clearly needed.

🏥 Post-Surgery Considerations

Inform your surgeon and anesthesiologist that you are taking this medicine before any surgery. It may need to be stopped temporarily.

🦷 Dental Procedures

Inform your dentist that you are taking this medicine before any dental procedure. No specific precautions are usually needed, but it is important for your dentist to know your medication history.

💚 Lifestyle Tips for Better Results

🏃
Maintain good hygiene to prevent secondary infections.
🥗
Elevate swollen limbs to reduce lymphedema.
😴
Wear loose-fitting clothing and footwear.
💧
Avoid mosquito bites by using repellents and bed nets.
🧘
Stay hydrated and eat a balanced diet.
🌞
Get adequate rest and sleep.

🏋️ Exercise Considerations

If you have lymphedema, avoid strenuous exercise that may worsen swelling. Gentle exercises like walking and swimming can help improve circulation. Consult your doctor before starting any exercise program.

🥗 Diet Recommendations

Include plenty of fruits and vegetables.
Reduce salt intake to manage swelling.
Stay well hydrated.
Avoid alcohol while taking this medicine.

💼 Impact on Daily Work & Life

This medicine may cause dizziness or drowsiness. Avoid driving or operating heavy machinery until you know how it affects you. Most people can continue their normal daily activities with caution.

🛑 When to Stop This Medicine

Do not stop taking this medicine without consulting your doctor. Complete the full course as prescribed. If you experience severe side effects, contact your doctor immediately for advice.

📅 Long-Term Use Effects

Long-term use of this medicine is generally not required for filarial infections, as treatment courses are typically 12 to 21 days. However, in rare cases of prolonged use, monitoring of liver and kidney function may be advised. There is no evidence of significant long-term toxicity when used as prescribed.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Ivermectin

Another antifilarial medicine that may be used alone or in combination with other drugs.

Evidence: Well-established
Albendazole

Often used in combination with diethylcarbamazine or ivermectin for mass drug administration.

Evidence: Well-established
Doxycycline

May be used as an adjunct to target Wolbachia bacteria that live inside the filarial worms.

Evidence: Emerging

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

There are no known interactions between this medicine and vaccines. However, consult your doctor before receiving any vaccine while on this medicine.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

When traveling, carry this medicine in its original packaging along with a copy of your prescription. Store it at room temperature and protect it from direct sunlight and moisture. If you are crossing time zones, adjust your dosing schedule gradually to avoid missing doses. Check the customs regulations of your destination country regarding prescription medicines. Always carry enough supply for your entire trip.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 35-year-old man from a filariasis-endemic area presented with swelling in his left leg and fever.
He was diagnosed with lymphatic filariasis and started on this medicine. After the first dose, he developed fever and a rash, which his doctor identified as the Mazzotti reaction. He was managed with antihistamines and continued the treatment. Over the next two weeks, his swelling reduced significantly and his fever subsided.
💡 Lesson: The Mazzotti reaction is common and can be managed with supportive care. It is important to continue treatment under medical supervision.
👤 A 50-year-old woman with tropical pulmonary eosinophilia experienced chronic cough and wheezing.
She was prescribed this medicine for 21 days. Her symptoms improved within the first week. She experienced mild nausea, which was managed by taking the medicine with food. She completed the full course and her follow-up tests showed no microfilariae.
💡 Lesson: Taking this medicine with food helps reduce gastrointestinal side effects. Completing the full course is essential for a cure.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: This medicine starts killing microfilariae within hours, but clinical improvement may take several days to weeks. Complete the full course as prescribed.

Q: Can I take this medicine with food?

A: Yes, it is best taken after a meal to reduce stomach upset.

Q: What should I do if I miss a dose?

A: Take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose.

Q: Is this medicine safe during pregnancy?

A: Consult your doctor. It should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus.

Q: Can I stop taking this medicine if I feel better?

A: No, you must complete the full course as prescribed to ensure the infection is fully cleared and to prevent recurrence.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my kidney function?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?
  • Is it safe during pregnancy?
  • How long does it take to work?

🔄 Substitutes for dicarb 100mg tablet

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: This medicine can cure all types of worm infections.
    Fact: This medicine is specifically effective against filarial worms. It is not a broad-spectrum deworming medicine.
  • Myth: You can stop taking this medicine as soon as symptoms improve.
    Fact: You must complete the full course as prescribed to ensure the infection is fully cleared and to prevent recurrence.
  • Myth: This medicine is safe to take without a prescription.
    Fact: This medicine should only be taken under medical supervision. Self-medication can lead to serious side effects.

🔄 Alternative Options

Generic Alternatives

  • Diethylcarbamazine 100 mg tablet (generic)

Brand Alternatives

  • Dicarb 100mg tablet

📊 Comparison with Similar Medicines

[{"medicine":"Diethylcarbamazine","class":"Piperazine derivative","primary_use":"Lymphatic filariasis","route":"Oral","common_side_effects":"Nausea, headache, dizziness"},{"medicine":"Ivermectin","class":"Avermectin","primary_use":"Lymphatic filariasis, onchocerciasis","route":"Oral","common_side_effects":"Dizziness, nausea, Mazzotti reaction"},{"medicine":"Albendazole","class":"Benzimidazole","primary_use":"Lymphatic filariasis, intestinal worms","route":"Oral","common_side_effects":"Abdominal pain, nausea, headache"}]

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